Best TWAS P=6.37e-283 · Best GWAS P=8.13e-305 conditioned to 3.03e-80
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | HERC2 | 0.07 | 0.00 | bslmm | 317 | 0.01 | 6.7e-03 | 35.1 | 25.5 | 8.8e-144 | 0.35 | 0.04 | 0.21 | TRUE |
| 2 | CommonMind | Brain Pre-frontal Cortex | OCA2 | 0.07 | 0.02 | bslmm | 474 | 0.02 | 7.2e-04 | 1.4 | 7.1 | 1.1e-12 | 0.15 | 0.52 | 0.22 | TRUE |
| 3 | GTEx | Whole Blood | HERC2 | 0.29 | 0.28 | lasso | 4 | 0.28 | 9.2e-26 | 33.1 | 33.6 | 8.0e-248 | 0.52 | 1.00 | 0.00 | FALSE |
| 4 | YFS | Blood | HERC2 | 0.10 | 0.10 | bslmm | 279 | 0.10 | 1.1e-30 | 35.8 | 35.9 | 6.4e-283 | 0.54 | 1.00 | 0.00 | TRUE |
| 5 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | OCA2 | 0.28 | 0.12 | lasso | 5 | 0.09 | 4.4e-05 | 7.7 | 6.9 | 5.1e-12 | 0.19 | 0.70 | 0.02 | TRUE |