Best TWAS P=6.98e-08 · Best GWAS P=1.02e-07 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | CASS4 | 0.38 | 0.21 | enet | 15 | 0.24 | 4.3e-18 | -5.3 | -5.4 | 7.0e-08 | 0.97 | 0 | 1 | TRUE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | CASS4 | 0.06 | 0.06 | enet | 4 | 0.06 | 4.3e-12 | -5.3 | -5.4 | 7.2e-08 | 0.99 | 0 | 1 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CASS4 | 0.07 | 0.07 | lasso | 1 | 0.07 | 2.9e-08 | -5.3 | -5.3 | 1.0e-07 | 1.00 | 0 | 1 | FALSE |