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chr19:44,190,626-46,967,227

Best TWAS P=1.89e-197 · Best GWAS P=1.75e-208 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	CLPTM1	0.11	0.09	enet	10	0.08	2.0e-10	5.71	-9.2	2.3e-20	-0.01	1.00	0.00	FALSE
2	CommonMind	Brain Pre-frontal Cortex	PVR	0.22	0.17	enet	26	0.17	2.3e-20	-7.57	-5.7	1.6e-08	0.06	1.00	0.00	TRUE
3	CommonMind	Brain Pre-frontal Cortex	PVRL2	0.10	0.03	lasso	2	0.03	9.2e-05	-3.37	-13.5	1.4e-41	-0.07	0.68	0.03	TRUE
4	GTEx	Adipose Subcutaneous	CEACAM19	0.13	0.11	enet	9	0.12	4.6e-10	9.31	9.5	1.7e-21	-0.11	0.98	0.00	FALSE
5	GTEx	Adipose Visceral Omentum	ZNF285	0.17	0.05	enet	20	0.07	1.3e-04	-2.20	-20.1	1.9e-89	0.17	0.39	0.15	TRUE
6	GTEx	Adrenal Gland	CEACAM19	0.31	0.17	lasso	5	0.18	5.8e-07	9.31	8.4	4.9e-17	-0.12	0.21	0.06	FALSE
7	GTEx	Artery Coronary	CEACAM19	0.28	0.23	lasso	4	0.22	4.4e-08	9.31	8.4	5.7e-17	-0.11	0.62	0.02	FALSE
8	GTEx	Artery Tibial	VASP	0.08	0.00	enet	19	0.00	5.5e-01	-2.83	6.7	2.1e-11	-0.07	0.09	0.05	TRUE
9	GTEx	Artery Tibial	ZNF229	0.20	0.06	enet	40	0.05	7.2e-05	2.85	5.7	1.2e-08	-0.08	0.23	0.04	TRUE
10	GTEx	Artery Tibial	CEACAM19	0.26	0.14	lasso	12	0.20	2.7e-15	9.31	8.5	2.2e-17	-0.16	1.00	0.00	FALSE
11	GTEx	Cells Transformed fibroblasts	PVR	0.27	0.09	lasso	8	0.12	1.2e-09	-8.22	-6.2	4.3e-10	0.08	1.00	0.00	FALSE
12	GTEx	Cells Transformed fibroblasts	CEACAM19	0.35	0.26	lasso	2	0.28	8.7e-21	9.31	9.0	2.6e-19	-0.12	1.00	0.00	TRUE
13	GTEx	Cells Transformed fibroblasts	CTB-179K24.3	0.15	0.12	enet	7	0.09	1.6e-07	-3.08	-6.9	5.0e-12	0.10	0.99	0.00	TRUE
14	GTEx	Colon Transverse	CEACAM19	0.34	0.24	lasso	5	0.25	3.6e-12	9.31	8.6	9.6e-18	-0.15	1.00	0.00	FALSE
15	GTEx	Esophagus Muscularis	CEACAM19	0.19	0.06	lasso	5	0.08	8.6e-06	9.31	6.1	1.1e-09	-0.06	0.54	0.02	FALSE
16	GTEx	Esophagus Muscularis	CTB-179K24.3	0.15	0.10	enet	12	0.07	4.5e-05	-3.08	-5.2	1.8e-07	-0.05	0.44	0.02	TRUE
17	GTEx	Liver	PVRL2	0.29	0.24	lasso	4	0.21	1.4e-06	-9.68	9.6	8.9e-22	0.12	0.21	0.05	TRUE
18	GTEx	Nerve Tibial	CEACAM19	0.19	0.04	lasso	7	0.09	7.4e-07	9.31	7.0	2.5e-12	-0.14	0.27	0.03	FALSE
19	GTEx	Pancreas	BCAM	0.29	0.01	lasso	6	0.00	2.6e-01	3.49	-5.2	2.1e-07	0.11	0.04	0.09	FALSE
20	GTEx	Skin Not Sun Exposed Suprapubic	ZNF229	0.28	0.09	enet	58	0.08	2.2e-05	-2.97	-21.4	6.2e-102	-0.03	0.17	0.16	FALSE
21	GTEx	Skin Sun Exposed Lower leg	PVR	0.11	0.05	lasso	2	0.06	2.1e-05	-7.57	-6.0	2.4e-09	0.04	0.84	0.01	FALSE
22	GTEx	Stomach	BCAM	0.33	0.00	enet	3	0.01	9.6e-02	2.58	-7.0	2.7e-12	0.09	0.07	0.07	FALSE
23	GTEx	Testis	CEACAM19	0.26	0.05	enet	33	0.06	1.1e-03	-7.57	8.2	1.8e-16	-0.15	0.18	0.05	TRUE
24	GTEx	Thyroid	CEACAM19	0.34	0.28	enet	26	0.30	9.9e-24	9.31	14.9	2.6e-50	-0.18	1.00	0.00	TRUE
25	METSIM	Adipose	CEACAM19	0.24	0.07	enet	29	0.12	7.7e-18	-2.39	7.9	2.3e-15	-0.13	1.00	0.00	FALSE
26	NTR	Blood	KLC3	0.02	0.00	blup	367	0.00	2.6e-02	-2.92	-6.8	1.5e-11	0.14	0.31	0.02	TRUE
27	NTR	Blood	SIX5	0.03	0.00	blup	381	0.00	2.6e-02	2.00	5.2	2.2e-07	-0.09	0.01	0.10	TRUE
28	YFS	Blood	TOMM40	0.04	0.00	bslmm	371	0.01	2.6e-04	-15.34	14.4	2.6e-47	0.09	0.03	0.36	TRUE
29	The Cancer Genome Atlas	Breast Invasive Carcinoma	APOC1	0.08	0.07	lasso	2	0.07	1.5e-13	7.50	7.5	5.3e-14	-0.02	1.00	0.00	FALSE
30	The Cancer Genome Atlas	Breast Invasive Carcinoma	APOC4	0.09	0.12	enet	6	0.11	5.9e-22	7.50	6.4	2.0e-10	0.01	1.00	0.00	FALSE
31	The Cancer Genome Atlas	Breast Invasive Carcinoma	APOE	0.06	0.05	lasso	2	0.04	7.9e-09	7.50	7.5	8.8e-14	-0.03	1.00	0.00	FALSE
32	The Cancer Genome Atlas	Breast Invasive Carcinoma	BLOC1S3	0.03	0.01	blup	31	0.02	1.4e-05	-0.87	7.7	1.3e-14	0.00	0.10	0.12	TRUE
33	The Cancer Genome Atlas	Glioblastoma Multiforme	GEMIN7	0.24	0.05	lasso	3	0.13	9.6e-05	11.02	10.0	1.6e-23	-0.14	0.01	0.64	TRUE
34	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CEACAM16	0.04	0.00	enet	6	0.02	1.4e-03	-9.55	10.1	3.9e-24	-0.17	0.03	0.16	FALSE
35	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	APOC1	0.05	0.03	enet	4	0.04	5.4e-05	7.50	6.5	9.0e-11	-0.01	0.55	0.01	TRUE
36	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	APOC1P1	0.05	0.03	blup	37	0.03	5.2e-04	-20.91	28.3	1.3e-175	0.53	0.14	0.20	FALSE
37	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	APOC4	0.11	0.10	lasso	8	0.12	9.3e-14	3.99	7.3	3.7e-13	-0.04	1.00	0.00	FALSE
38	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PVR	0.08	0.10	lasso	4	0.09	9.8e-11	-8.32	-7.8	4.1e-15	0.06	0.90	0.10	FALSE
39	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TOMM40	0.04	0.03	lasso	2	0.02	1.4e-03	-30.09	30.0	1.9e-197	0.65	0.12	0.09	TRUE
40	The Cancer Genome Atlas	Brain Lower Grade Glioma	APOC1P1	0.17	0.04	enet	10	0.09	3.2e-10	-25.35	6.2	4.1e-10	0.60	1.00	0.00	FALSE
41	The Cancer Genome Atlas	Brain Lower Grade Glioma	APOC4	0.06	0.03	blup	34	0.04	8.4e-06	3.66	12.2	4.3e-34	0.14	0.70	0.02	TRUE
42	The Cancer Genome Atlas	Brain Lower Grade Glioma	CEACAM19	0.08	0.05	lasso	4	0.05	3.3e-06	9.31	9.5	2.5e-21	-0.13	0.01	0.98	FALSE
43	The Cancer Genome Atlas	Brain Lower Grade Glioma	PVR	0.14	0.01	blup	51	0.06	3.4e-07	-8.22	-6.3	2.4e-10	-0.04	0.01	0.90	TRUE
44	The Cancer Genome Atlas	Brain Lower Grade Glioma	PVRL2	0.04	0.01	blup	55	0.02	1.5e-03	-7.34	8.3	8.0e-17	-0.26	0.04	0.04	FALSE
45	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	PVRL2	0.09	0.01	blup	57	0.04	4.0e-03	-9.68	-5.7	1.1e-08	-0.23	0.06	0.04	TRUE
46	The Cancer Genome Atlas	Lung Adenocarcinoma	APOC1P1	0.03	0.00	blup	37	0.01	1.5e-02	-7.68	6.0	2.1e-09	0.51	0.02	0.03	FALSE
47	The Cancer Genome Atlas	Lung Adenocarcinoma	APOC4	0.09	0.07	blup	34	0.09	1.2e-10	4.56	6.1	9.2e-10	-0.04	1.00	0.00	TRUE
48	The Cancer Genome Atlas	Lung Adenocarcinoma	APOE	0.04	0.04	lasso	4	0.04	2.2e-05	7.50	7.2	6.3e-13	-0.02	0.58	0.02	FALSE
49	The Cancer Genome Atlas	Lung Adenocarcinoma	NKPD1	0.03	0.00	blup	37	0.01	4.5e-02	6.82	-8.7	4.2e-18	0.12	0.02	0.47	FALSE
50	The Cancer Genome Atlas	Lung Adenocarcinoma	PVR	0.03	0.02	blup	51	0.02	1.4e-03	-8.22	-6.2	5.9e-10	0.06	0.08	0.03	TRUE
51	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	APOC1	0.05	0.00	blup	47	0.01	4.3e-02	-1.06	-22.7	3.4e-114	0.32	0.01	0.06	TRUE
52	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	APOE	0.06	0.00	blup	49	0.01	4.5e-02	-1.06	-18.3	6.5e-75	0.19	0.02	0.06	FALSE
53	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	APOC2	0.27	0.18	enet	12	0.29	1.1e-19	5.48	-7.4	1.0e-13	-0.15	1.00	0.00	TRUE
54	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	APOC2	0.18	0.12	enet	14	0.13	5.2e-06	3.66	10.3	8.9e-25	-0.11	0.65	0.03	FALSE
55	The Cancer Genome Atlas	Prostate Adenocarcinoma	APOE	0.10	0.08	lasso	4	0.07	6.7e-08	7.50	7.2	8.6e-13	-0.01	0.98	0.00	FALSE
56	The Cancer Genome Atlas	Prostate Adenocarcinoma	CEACAM19	0.15	0.08	lasso	3	0.07	4.0e-08	9.31	9.3	1.4e-20	-0.12	0.01	0.99	FALSE
57	The Cancer Genome Atlas	Prostate Adenocarcinoma	PVR	0.09	0.02	enet	18	0.07	1.4e-07	-4.09	-6.7	2.6e-11	0.05	0.24	0.28	FALSE
58	The Cancer Genome Atlas	Prostate Adenocarcinoma	PVRL2	0.10	0.04	blup	56	0.04	1.8e-05	-7.34	-7.8	6.7e-15	0.07	0.93	0.00	TRUE
59	The Cancer Genome Atlas	Prostate Adenocarcinoma	TOMM40	0.08	0.07	enet	13	0.07	2.2e-07	-30.09	18.9	4.7e-80	0.67	1.00	0.00	TRUE
60	The Cancer Genome Atlas	Prostate Adenocarcinoma	TRAPPC6A	0.03	0.02	blup	37	0.01	3.2e-02	7.02	-6.9	4.0e-12	0.08	0.07	0.17	TRUE
61	The Cancer Genome Atlas	Soft Tissue Sarcoma	APOC4	0.13	0.10	blup	34	0.13	3.2e-08	8.09	14.7	7.5e-49	-0.03	0.96	0.00	TRUE
62	The Cancer Genome Atlas	Stomach Adenocarcinoma	APOC4	0.07	0.09	lasso	2	0.09	3.2e-07	7.50	8.3	8.0e-17	-0.03	0.78	0.01	FALSE
63	The Cancer Genome Atlas	Testicular Germ Cell Tumors	APOC1P1	0.14	0.01	blup	36	0.06	3.8e-03	-3.37	19.3	3.6e-83	0.51	0.01	0.07	TRUE
64	The Cancer Genome Atlas	Testicular Germ Cell Tumors	APOC2	0.14	0.15	enet	5	0.16	3.5e-06	3.66	-5.2	2.1e-07	-0.07	0.43	0.03	FALSE
65	The Cancer Genome Atlas	Testicular Germ Cell Tumors	CEACAM19	0.17	0.11	enet	7	0.14	1.3e-05	9.31	8.1	4.2e-16	-0.16	0.01	0.86	FALSE
66	The Cancer Genome Atlas	Thyroid Carcinoma	BLOC1S3	0.08	0.06	blup	31	0.08	4.2e-08	-0.91	7.7	1.7e-14	-0.05	0.62	0.19	FALSE
67	The Cancer Genome Atlas	Thyroid Carcinoma	CEACAM19	0.26	0.13	lasso	3	0.14	4.0e-13	9.31	8.7	4.3e-18	-0.14	0.01	0.99	FALSE
68	The Cancer Genome Atlas	Thyroid Carcinoma	PVRL2	0.09	0.05	blup	55	0.03	4.6e-04	-2.73	-12.9	6.2e-38	0.45	0.48	0.05	TRUE
69	The Cancer Genome Atlas	Thyroid Carcinoma	TOMM40	0.05	0.07	lasso	3	0.06	1.1e-06	-26.50	25.1	1.4e-139	0.62	0.89	0.01	FALSE
70	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	APOC2	0.20	0.14	enet	10	0.14	7.9e-05	5.48	-13.7	7.1e-43	0.12	0.15	0.05	FALSE