Best TWAS P=2.71e-09 · Best GWAS P=5.62e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Liver | LCLAT1 | 0.34 | 0.24 | lasso | 4 | 0.18 | 7.2e-06 | -5.8 | -5.8 | 7.0e-09 | 0.99 | 0.00 | 0.99 | FALSE |
| 2 | GTEx | Pancreas | LCLAT1 | 0.23 | 0.09 | lasso | 6 | 0.07 | 7.0e-04 | -5.7 | -5.7 | 1.4e-08 | 0.93 | 0.01 | 0.98 | FALSE |
| 3 | GTEx | Stomach | LCLAT1 | 0.26 | 0.10 | lasso | 5 | 0.08 | 7.7e-05 | -5.8 | -6.0 | 2.7e-09 | 0.95 | 0.01 | 0.99 | TRUE |
| 4 | METSIM | Adipose | LCLAT1 | 0.13 | 0.10 | bslmm | 608 | 0.11 | 2.6e-16 | -5.7 | -5.2 | 1.7e-07 | 0.92 | 0.00 | 1.00 | FALSE |
| 5 | NTR | Blood | LCLAT1 | 0.15 | 0.25 | enet | 24 | 0.25 | 6.5e-81 | -5.8 | -5.4 | 5.4e-08 | 0.98 | 0.00 | 1.00 | FALSE |
| 6 | ROSMAP | Brain Pre-frontal Cortex | LCLAT1 | 0.06 | 0.03 | lasso | 4 | 0.02 | 5.7e-04 | -5.7 | -5.4 | 5.4e-08 | 0.96 | 0.00 | 1.00 | FALSE |
| 7 | YFS | Blood | LCLAT1 | 0.38 | 0.63 | bslmm | 593 | 0.63 | 7.7e-276 | -5.8 | -5.8 | 5.9e-09 | 0.99 | 0.00 | 1.00 | FALSE |
| 8 | The Cancer Genome Atlas | Lung Adenocarcinoma | LCLAT1 | 0.08 | 0.06 | blup | 137 | 0.04 | 7.6e-06 | -5.4 | -5.2 | 2.4e-07 | 0.76 | 0.04 | 0.96 | FALSE |
| 9 | The Cancer Genome Atlas | Prostate Adenocarcinoma | LCLAT1 | 0.04 | 0.02 | blup | 137 | 0.03 | 5.6e-04 | -5.4 | -5.3 | 9.6e-08 | 0.81 | 0.02 | 0.95 | FALSE |