Best TWAS P=2.46e-08 · Best GWAS P=1.68e-08 conditioned to 0.0171
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ETV7 | 0.04 | 0.01 | lasso | 7 | 0.04 | 5.3e-08 | -3.6 | 5.4 | 7.9e-08 | -0.75 | 0.03 | 0.97 | FALSE |
| 2 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | ETV7 | 0.07 | 0.02 | blup | 63 | 0.04 | 1.1e-03 | -3.9 | 5.2 | 1.9e-07 | -0.76 | 0.02 | 0.80 | FALSE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | ETV7 | 0.08 | 0.11 | enet | 6 | 0.11 | 3.6e-11 | -3.9 | 5.2 | 2.6e-07 | -0.68 | 0.81 | 0.14 | FALSE |
| 4 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | ETV7 | 0.15 | 0.01 | blup | 67 | 0.04 | 2.0e-02 | -5.6 | 5.6 | 2.5e-08 | -0.71 | 0.01 | 0.62 | TRUE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | ETV7 | 0.10 | 0.08 | enet | 2 | 0.08 | 5.4e-08 | -5.5 | 5.6 | 2.7e-08 | -0.81 | 0.00 | 1.00 | FALSE |