Best TWAS P=1.44e-08 · Best GWAS P=3.81e-09 conditioned to 0.0383
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | ICAM5 | 0.03 | 0.02 | blup | 48 | 0.02 | 0.0045 | 5.3 | 5.7 | 1.4e-08 | 0.84 | 0.01 | 0.90 | TRUE |
2 | The Cancer Genome Atlas | Rectum Adenocarcinoma | MRPL4 | 0.24 | 0.14 | blup | 40 | 0.10 | 0.0025 | 5.5 | 5.2 | 2.1e-07 | 0.91 | 0.00 | 0.77 | FALSE |