[Hub]/) : Traits : Allergy or Eczema :

chr18:51,100,222-52,540,420

Best TWAS P=5.98e-11 · Best GWAS P=8.7e-11 conditioned to 0.173

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous POLI 0.55 0.37 lasso 5 0.44 7.6e-40 -6.4 5.4 5.5e-08 -0.96 0.00 1.00 FALSE
2 GTEx Adipose Visceral Omentum POLI 0.36 0.34 enet 26 0.34 3.5e-18 -6.4 5.3 1.2e-07 -0.93 0.00 1.00 FALSE
3 GTEx Artery Aorta POLI 0.26 0.23 lasso 6 0.23 5.4e-13 -6.4 5.7 1.2e-08 -0.94 0.00 1.00 FALSE
4 GTEx Artery Coronary POLI 0.54 0.18 lasso 30 0.13 4.1e-05 -6.4 5.4 8.3e-08 -0.89 0.00 1.00 FALSE
5 GTEx Artery Tibial POLI 0.50 0.31 lasso 8 0.36 2.5e-29 -6.4 6.0 2.4e-09 -0.96 0.00 1.00 FALSE
6 GTEx Brain Cerebellar Hemisphere POLI 0.48 0.38 lasso 7 0.34 1.3e-09 -6.4 6.2 6.1e-10 -0.98 0.00 1.00 FALSE
7 GTEx Brain Cerebellum POLI 0.52 0.32 lasso 5 0.34 8.8e-11 -6.4 5.9 3.9e-09 -0.95 0.00 1.00 FALSE
8 GTEx Breast Mammary Tissue POLI 0.33 0.28 lasso 7 0.32 6.8e-17 -6.4 5.6 2.4e-08 -0.95 0.00 1.00 FALSE
9 GTEx Breast Mammary Tissue (Male) POLI 0.31 0.35 lasso 3 0.32 4.5e-08 -6.4 6.4 2.0e-10 -1.00 0.00 1.00 FALSE
10 GTEx Cells EBV-transformed lymphocytes POLI 0.33 0.30 lasso 5 0.34 1.0e-11 -6.4 5.9 2.7e-09 -0.95 0.00 1.00 FALSE
11 GTEx Cells Transformed fibroblasts POLI 0.46 0.36 enet 18 0.36 9.9e-28 -6.4 6.2 7.4e-10 -0.97 0.00 1.00 FALSE
12 GTEx Colon Transverse POLI 0.24 0.26 lasso 4 0.25 4.5e-12 -6.4 6.1 1.2e-09 -0.99 0.00 1.00 FALSE
13 GTEx Esophagus Gastroesophageal Junction POLI 0.21 0.19 lasso 4 0.30 2.0e-11 3.3 5.3 1.2e-07 -0.88 0.01 0.99 FALSE
14 GTEx Esophagus Mucosa POLI 0.42 0.26 lasso 5 0.29 1.2e-19 -6.4 5.5 3.5e-08 -0.96 0.00 1.00 FALSE
15 GTEx Esophagus Muscularis POLI 0.30 0.20 lasso 7 0.29 4.3e-18 3.2 5.1 3.0e-07 -0.89 0.01 0.99 FALSE
16 GTEx Heart Atrial Appendage POLI 0.29 0.26 enet 12 0.28 3.8e-13 -6.4 5.8 8.5e-09 -0.94 0.00 1.00 FALSE
17 GTEx Heart Left Ventricle POLI 0.12 0.09 lasso 10 0.10 6.7e-06 -6.4 5.8 8.9e-09 -0.95 0.00 1.00 FALSE
18 GTEx Lung POLI 0.39 0.31 lasso 5 0.35 2.1e-27 -6.5 6.0 1.4e-09 -0.96 0.00 1.00 FALSE
19 GTEx Muscle Skeletal POLI 0.30 0.13 lasso 12 0.13 1.2e-12 -6.5 5.2 1.7e-07 -0.94 0.00 1.00 FALSE
20 GTEx Spleen POLI 0.44 0.26 lasso 3 0.36 3.4e-10 3.2 5.3 1.3e-07 -0.87 0.01 0.99 FALSE
21 GTEx Testis POLI 0.32 0.25 lasso 4 0.23 1.4e-10 -6.4 6.2 7.3e-10 -0.98 0.00 1.00 FALSE
22 GTEx Thyroid POLI 0.47 0.37 enet 14 0.44 3.3e-36 -6.4 5.7 1.4e-08 -0.94 0.00 1.00 FALSE
23 GTEx Whole Blood POLI 0.05 0.04 enet 8 0.05 1.6e-05 -6.4 5.9 4.0e-09 -0.92 0.00 1.00 FALSE
24 METSIM Adipose POLI 0.23 0.27 enet 25 0.27 2.8e-40 -6.4 5.8 5.9e-09 -0.97 0.00 1.00 FALSE
25 NTR Blood POLI 0.09 0.05 enet 19 0.07 9.2e-22 -6.4 5.3 1.1e-07 -0.89 0.00 1.00 FALSE
26 YFS Blood POLI 0.05 0.05 lasso 3 0.05 1.1e-15 -6.4 5.8 6.8e-09 -0.94 0.00 1.00 FALSE
27 The Cancer Genome Atlas Bladder Urothelial Carcinoma POLI 0.18 0.12 lasso 3 0.11 8.2e-10 -6.4 6.3 2.4e-10 -1.00 0.00 1.00 FALSE
28 The Cancer Genome Atlas Breast Invasive Carcinoma POLI 0.11 0.11 lasso 4 0.11 2.1e-22 -6.5 6.3 3.5e-10 -0.99 0.00 1.00 FALSE
29 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma POLI 0.16 0.13 lasso 3 0.13 2.0e-14 -6.4 6.4 1.5e-10 -1.00 0.00 1.00 FALSE
30 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma POLI 0.18 0.16 enet 4 0.16 1.4e-17 -6.4 6.2 5.0e-10 -0.99 0.00 1.00 FALSE
31 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma POLI 0.10 0.04 blup 43 0.05 8.4e-04 -6.4 5.6 2.6e-08 -0.93 0.00 0.98 FALSE
32 The Cancer Genome Atlas Brain Lower Grade Glioma POLI 0.20 0.17 lasso 6 0.18 3.6e-20 -6.5 5.8 7.6e-09 -0.97 0.00 1.00 FALSE
33 The Cancer Genome Atlas Lung Adenocarcinoma POLI 0.08 0.07 blup 43 0.08 7.1e-10 -6.5 6.5 6.0e-11 -0.90 0.00 1.00 TRUE
34 The Cancer Genome Atlas Lung Squamous Cell Carcinoma POLI 0.11 0.07 blup 43 0.09 4.5e-10 -6.4 5.7 1.3e-08 -0.86 0.00 1.00 FALSE
35 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma POLI 0.23 0.15 lasso 4 0.16 6.0e-11 -6.4 6.2 4.2e-10 -0.95 0.00 1.00 FALSE
36 The Cancer Genome Atlas Pancreatic Adenocarcinoma POLI 0.20 0.17 lasso 4 0.14 1.6e-06 -6.4 6.5 9.7e-11 -0.99 0.00 1.00 FALSE
37 The Cancer Genome Atlas Prostate Adenocarcinoma POLI 0.16 0.17 lasso 7 0.17 3.5e-17 -6.5 6.1 9.5e-10 -0.99 0.00 1.00 FALSE
38 The Cancer Genome Atlas Rectum Adenocarcinoma POLI 0.20 0.03 blup 43 0.05 3.3e-02 -6.4 6.5 8.8e-11 -0.79 0.00 0.60 FALSE
39 The Cancer Genome Atlas Soft Tissue Sarcoma POLI 0.10 0.07 lasso 2 0.06 2.7e-04 -6.4 6.4 1.6e-10 -1.00 0.00 0.98 FALSE
40 The Cancer Genome Atlas Stomach Adenocarcinoma POLI 0.13 0.11 enet 5 0.11 1.8e-08 -6.4 6.2 5.9e-10 -0.97 0.00 1.00 FALSE
41 The Cancer Genome Atlas Testicular Germ Cell Tumors POLI 0.14 0.05 lasso 3 0.04 1.1e-02 -6.4 6.1 9.1e-10 -0.98 0.00 0.97 FALSE
42 The Cancer Genome Atlas Thyroid Carcinoma POLI 0.24 0.28 lasso 2 0.28 7.3e-27 -6.5 6.4 1.3e-10 -1.00 0.00 1.00 FALSE