Best TWAS P=3.73e-10 · Best GWAS P=4.82e-10 conditioned to 0.0832
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Breast Mammary Tissue (Female) | RP11-53O19.1 | 0.06 | -0.01 | lasso | 4 | 0.00 | 0.301 | 5.8 | 5.1 | 3.0e-07 | 0.88 | 0.03 | 0.19 | FALSE |
2 | GTEx | Esophagus Gastroesophageal Junction | RP11-53O19.3 | 0.08 | 0.05 | lasso | 3 | 0.02 | 0.059 | 6.0 | -6.3 | 3.7e-10 | -0.85 | 0.03 | 0.75 | TRUE |