Best TWAS P=8.95e-09 · Best GWAS P=1.38e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | MCHR1 | 0.15 | 0.07 | lasso | 7 | 0.14 | 7.5e-17 | 5.4 | -5.7 | 1.1e-08 | 0.77 | 0.01 | 0.99 | FALSE |
| 2 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | XPNPEP3 | 0.07 | 0.05 | enet | 6 | 0.07 | 1.2e-06 | 4.0 | 5.4 | 6.8e-08 | -0.90 | 0.01 | 0.99 | FALSE |
| 3 | The Cancer Genome Atlas | Colon Adenocarcinoma | XPNPEP3 | 0.10 | 0.06 | lasso | 3 | 0.06 | 1.4e-04 | -5.6 | 5.8 | 9.0e-09 | -0.96 | 0.00 | 0.99 | TRUE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | XPNPEP3 | 0.23 | 0.26 | lasso | 5 | 0.26 | 1.5e-29 | -5.0 | 5.2 | 2.3e-07 | -0.92 | 0.03 | 0.97 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | XPNPEP3 | 0.33 | 0.38 | lasso | 4 | 0.40 | 7.4e-41 | -5.0 | 5.1 | 3.0e-07 | -0.85 | 0.03 | 0.97 | FALSE |