Best TWAS P=9.55e-08 · Best GWAS P=4.5e-08 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Visceral Omentum | ADD3 | 0.06 | 0.03 | enet | 7 | 0.04 | 4.1e-03 | 4.9 | 5.3 | 9.6e-08 | 0.95 | 0.04 | 0.93 | TRUE |
2 | GTEx | Heart Left Ventricle | ADD3 | 0.10 | 0.02 | enet | 17 | 0.03 | 1.2e-02 | 4.9 | 5.2 | 2.5e-07 | 0.79 | 0.05 | 0.93 | FALSE |
3 | GTEx | Spleen | ADD3 | 0.36 | 0.27 | lasso | 5 | 0.28 | 7.2e-08 | 4.6 | 5.3 | 1.1e-07 | 0.89 | 0.08 | 0.88 | FALSE |