TWAS hub - ADD3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0580	0.0240	1.4e-03	0.032	0.039	0.039	0.041	0.020	8.3e-05	1.4e-05	1.2e-05	8.5e-06	1.3e-03
2	GTEx	Adipose Visceral Omentum	0.0560	0.0260	4.4e-03	0.035	NA	0.039	NA	0.034	6.6e-03	NA	4.1e-03	NA	7.2e-03
3	GTEx	Artery Aorta	0.1240	0.0430	1.3e-05	0.103	NA	0.093	NA	0.112	2.8e-06	NA	7.8e-06	NA	9.4e-07
4	GTEx	Brain Cerebellar Hemisphere	0.3950	0.0840	3.2e-09	0.339	NA	0.434	NA	0.453	1.6e-09	NA	1.8e-12	NA	4.2e-13
5	GTEx	Brain Cerebellum	0.3600	0.0770	1.4e-08	0.309	NA	0.311	NA	0.332	7.8e-10	NA	6.8e-10	NA	1.4e-10
6	GTEx	Breast Mammary Tissue	0.0820	0.0420	8.5e-03	0.053	NA	0.010	NA	0.041	1.1e-03	NA	9.9e-02	NA	3.4e-03
7	GTEx	Breast Mammary Tissue (Male)	0.1869	0.1097	8.3e-02	-0.006	NA	-0.013	NA	-0.002	4.8e-01	NA	9.0e-01	NA	3.5e-01
8	GTEx	Breast Mammary Tissue (Female)	0.0742	0.0522	5.8e-02	0.021	NA	0.002	NA	0.089	7.8e-02	NA	2.7e-01	NA	1.3e-03
9	GTEx	Colon Sigmoid	0.1040	0.0460	2.4e-03	0.041	NA	0.027	NA	0.029	1.4e-02	NA	3.8e-02	NA	3.3e-02
10	GTEx	Heart Left Ventricle	0.0973	0.0389	2.4e-04	0.018	NA	0.028	NA	0.020	3.5e-02	NA	1.2e-02	NA	2.8e-02
11	GTEx	Lung	0.0671	0.0285	7.5e-04	0.052	NA	0.038	NA	0.045	7.1e-05	NA	6.1e-04	NA	2.2e-04
12	GTEx	Nerve Tibial	0.0788	0.0345	9.6e-04	0.075	NA	0.016	NA	0.044	5.6e-06	NA	2.6e-02	NA	4.3e-04
13	GTEx	Pituitary	0.2670	0.0980	3.7e-04	0.052	NA	0.083	NA	0.048	1.9e-02	NA	4.0e-03	NA	2.4e-02
14	GTEx	Skin Sun Exposed Lower leg	0.1300	0.0520	1.0e-03	-0.001	NA	0.013	NA	0.003	3.8e-01	NA	2.6e-02	NA	1.9e-01
15	GTEx	Spleen	0.3620	0.1000	6.3e-05	0.267	NA	0.266	NA	0.279	1.6e-07	NA	1.6e-07	NA	7.2e-08
16	GTEx	Thyroid	0.0590	0.0320	6.7e-03	0.000	NA	0.005	NA	0.003	3.2e-01	NA	1.2e-01	NA	1.7e-01
17	ROSMAP	Brain Pre-frontal Cortex	0.0396	0.0174	7.8e-04	0.029	0.008	0.006	0.010	0.018	1.1e-04	2.6e-02	4.3e-02	1.6e-02	2.1e-03
18	TCGA	Brain Lower Grade Glioma	0.0432	0.0348	6.1e-03	0.034	0.010	0.008	NA	0.024	9.4e-05	2.2e-02	4.1e-02	NA	8.5e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Bipolar Disorder (2018)	13.2	20.8	28.5	3.4	5.3	4.5	5.1	4.8	4.7	3.0	4.8	4.9	5.2	4.7	4.9	4.7	1.6	5.3	5.0	4.9	3.7
Schizophrenia vs Biploar Disorder	7.2	9.6	17.0	-2.9	-3.2	-2.4	-3.6	-3.9	-2.5	-1.4	-3.9	-2.6	-3.6	-4.1	-2.6	-3.1	-1.8	-3.3	-2.7	-2.8	-3.7
Myopia	7.2	10.5	14.7	2.7	3.6	3.4	3.5	3.8	3.1	0.1	3.8	3.3	2.9	3.5	3.3	3.8	-0.8	3.6	3.3	3.5	3.4
Taking other prescription medications	6.5	10.0	16.9	-2.8	-3.4	-3.1	-3.6	-3.5	-3.1	-0.5	-4.1	-3.4	-2.5	-3.2	-3.3	-3.7	0.4	-3.4	-3.4	-3.3	-3.5
Blood Eosinophil Count	6.1	46.7	63.5	-4.8	-7.0	-7.1	-8.0	-7.8	-7.7	-3.6	-7.4	-7.5	-7.1	-7.1	-7.7	-7.5	-1.4	-7.7	-7.9	-6.4	-5.3
Diabetes (father)	6.1	7.5	11.6	-0.9	-3.1	-3.4	-2.7	-2.2	-3.3	-0.7	-2.4	-3.2	-3.1	-2.0	-3.4	-3.0	-1.2	-3.1	-3.4	-3.0	-2.9
Number of children fathered	5.7	6.4	10.0	-0.1	-2.7	-2.8	-2.8	-2.5	-3.1	-0.3	-2.7	-2.8	-3.2	-2.2	-3.1	-2.8	-1.7	-3.1	-3.1	-2.1	-1.8
Lung FEV1/FVC ratio	5.4	27.3	37.9	-5.5	-6.2	-5.4	-5.7	-5.4	-5.6	-2.7	-5.3	-5.3	-5.3	-5.2	-5.8	-5.3	-2.2	-6.0	-5.7	-5.8	-3.9
Number of operations (self-reported)	5.4	8.0	13.3	-2.0	-3.2	-2.8	-3.3	-3.2	-2.8	-1.3	-3.2	-2.9	-3.7	-3.0	-2.9	-2.9	0.8	-3.2	-3.0	-3.1	-2.1
Qualifications: College or University degree	5.3	16.7	27.2	2.2	4.2	5.2	4.3	4.1	5.0	1.3	3.8	4.9	3.9	3.7	5.0	4.8	-1.1	4.3	5.2	4.7	2.0
Rheumatoid Arthritis	4.7	6.5	8.9	-0.9	-3.0	-2.7	-2.9	-2.7	-2.7	-1.3	-2.9	-3.0	-2.7	-2.5	-2.7	-2.7	-1.5	-2.9	-2.9	-3.0	-1.9
Bipolar Disorder or Schizophrenia	4.4	10.7	15.0	2.9	3.9	3.6	3.7	3.1	3.8	2.1	3.1	3.8	2.9	2.8	3.8	3.7	0.6	3.6	3.8	3.8	1.6
Long-standing illness, disability or infirmity	4.4	6.7	12.1	-2.9	-2.5	-2.6	-3.3	-3.2	-2.7	-0.8	-3.5	-2.2	-1.7	-3.1	-2.7	-2.9	0.9	-2.8	-2.8	-2.3	-1.5
Mouth/teeth dental problems	4.2	6.5	8.9	2.5	2.8	2.8	2.8	2.7	2.7	1.4	2.6	2.4	2.1	2.8	2.8	2.8	-0.0	3.0	2.8	2.5	2.5
Eye problems/disorders: Cataract	4.0	4.7	7.3	-2.7	-2.5	-2.2	-2.6	-2.4	-1.9	-0.9	-2.5	-1.9	-2.0	-2.7	-2.0	-2.1	-0.1	-2.3	-2.0	-2.2	-2.3
Tinnitus: Yes, now most or all of the time	4.0	4.6	13.5	-3.7	-2.4	-1.8	-2.3	-2.3	-1.7	-3.5	-2.1	-1.7	-1.0	-2.1	-1.9	-1.8	1.3	-2.5	-1.7	-2.1	-1.1
Fluid intelligence score	3.7	7.7	20.5	1.7	2.7	3.0	2.8	2.9	2.5	-1.0	2.9	2.9	3.2	3.1	2.7	2.9	1.2	2.7	2.7	2.6	4.5
Medication: Seretide 50 evohaler	3.7	4.3	8.9	-2.3	-1.9	-1.8	-2.4	-2.6	-1.9	-2.7	-1.7	-2.0	-2.1	-3.0	-1.9	-2.1	0.9	-2.3	-2.0	-1.8	0.2
Wears glasses or contact lenses	3.7	4.3	6.7	-1.8	-2.6	-1.6	-2.5	-2.1	-2.1	-2.5	-2.1	-2.3	-2.4	-1.8	-2.1	-1.9	-0.5	-2.3	-2.0	-2.5	-0.8
Qualifications: None of the above	3.5	7.6	10.6	-3.0	-2.7	-3.3	-3.0	-3.0	-3.2	-0.1	-2.8	-3.0	-2.6	-2.9	-3.2	-3.1	0.5	-3.1	-3.2	-2.8	-1.1
Back pain experienced in last month	3.5	5.1	8.5	-2.0	-2.3	-2.3	-2.7	-2.7	-2.6	-0.3	-2.7	-2.6	-1.4	-2.2	-2.6	-2.9	0.9	-2.4	-2.5	-2.5	-0.5
Hearing difficulty/problems: Yes	3.4	5.1	7.9	-1.3	-2.4	-2.4	-2.6	-2.7	-2.7	-1.9	-2.5	-2.0	-2.0	-2.6	-2.6	-2.3	1.0	-2.8	-2.8	-2.1	-0.5
Family relationship satisfaction	3.4	4.2	8.2	1.5	2.2	2.0	2.9	2.4	2.1	1.4	2.7	2.2	1.6	2.1	2.1	2.3	0.1	2.3	2.1	2.0	1.3
Coronary Artery Disease (CAD)	3.3	3.9	6.1	-1.6	-2.3	-2.1	-2.2	-1.8	-2.4	-1.6	-1.8	-2.2	-1.0	-1.6	-2.4	-2.2	1.1	-2.5	-2.4	-2.3	-1.0
Mouth/teeth dental problems: Bleeding gums	3.3	4.3	6.9	-2.3	-2.3	-2.5	-2.1	-2.1	-2.5	-1.1	-1.8	-2.0	-1.3	-1.9	-2.6	-2.2	-0.4	-2.3	-2.6	-2.4	-1.4
Hayfever/allergic rhinitis (self-reported)	3.2	4.2	7.3	1.4	2.5	2.0	2.0	2.1	2.0	-0.3	2.0	2.2	1.9	2.2	2.2	2.2	1.3	2.1	2.1	2.5	2.7
Qualifications: nursing, teaching	3.2	5.0	7.6	1.8	2.0	2.3	2.8	2.6	2.4	2.1	2.0	2.2	2.4	2.4	2.4	2.0	0.8	2.4	2.6	2.1	2.0
Eye problems/disorders: Glaucoma	3.2	3.8	6.0	1.7	2.2	1.9	2.1	2.2	1.8	0.5	1.9	1.7	2.4	2.4	1.9	1.7	2.4	2.3	1.7	1.9	1.6
Pain experienced in last month	3.2	5.4	11.0	1.4	2.9	2.5	2.1	2.0	2.6	-0.7	2.1	3.2	0.5	1.7	2.7	3.2	-1.1	2.8	2.8	3.3	1.2
Bipolar Disorder (2011)	3.1	3.0	5.1	0.3	1.9	1.8	1.9	1.6	1.9	1.3	1.7	2.3	1.9	1.4	1.9	1.8	0.5	2.1	2.0	2.1	1.8
Financial difficulties in last 2 years	3.1	4.1	8.1	1.3	2.2	2.0	2.6	2.7	1.9	0.8	2.8	2.2	1.4	2.5	1.8	2.4	-0.4	2.4	2.0	2.2	1.1
Prospective memory result	3.1	3.8	5.5	-0.6	-1.9	-2.1	-1.8	-2.2	-2.0	1.0	-2.2	-2.2	-2.2	-2.3	-2.1	-2.2	0.8	-1.8	-2.1	-2.1	-2.1
Average weekly red wine intake	3.1	4.6	8.0	0.9	2.2	2.7	2.3	2.1	2.8	1.5	1.9	1.9	2.6	1.5	2.7	1.6	2.3	2.6	2.7	2.0	0.5
Number of self-reported non-cancer illnesses	3.1	5.3	9.4	-2.7	-1.6	-2.5	-2.9	-2.8	-2.3	-1.4	-3.1	-2.1	-1.6	-2.9	-2.2	-2.8	1.2	-2.3	-2.3	-1.7	-2.1
Medication: Levothyroxine sodium	3.0	5.1	9.5	-2.0	-2.4	-2.4	-2.6	-2.8	-2.2	-0.3	-3.1	-2.1	-2.0	-3.0	-2.2	-2.7	0.1	-2.8	-2.2	-2.0	-1.6
Hearing difficulty/problems with background noise	2.9	4.6	7.7	-0.4	-1.9	-2.5	-2.5	-2.7	-2.7	-0.3	-2.2	-2.2	-1.7	-2.5	-2.6	-2.8	0.9	-2.4	-2.8	-1.7	-0.9
Friendships satisfaction	2.9	3.6	6.7	1.3	2.3	1.9	2.1	2.2	1.9	-0.5	2.6	1.9	0.9	1.9	2.0	2.1	-0.5	2.1	1.8	2.4	1.9
Alzheimer’s Disease (including proxy)	2.8	4.0	5.8	-1.8	-2.4	-1.9	-2.4	-2.3	-2.1	-1.9	-2.1	-2.0	-1.8	-1.8	-2.1	-1.9	0.4	-2.4	-2.1	-2.3	-1.6
Verbal and Numeric Reasoning (VNR)	2.8	6.8	12.1	1.9	2.5	3.2	2.8	2.8	2.7	-0.5	2.7	2.7	3.0	3.0	2.7	2.7	0.8	2.6	2.7	2.3	3.5
Average weekly fortified wine intake	2.8	3.3	5.3	1.1	1.8	2.3	1.8	2.1	2.0	-0.9	2.0	2.0	1.7	2.2	2.1	2.1	0.5	1.8	2.1	1.9	1.2
Tense / ‘highly strung’	2.8	4.6	6.9	1.1	2.4	2.6	2.4	2.5	2.4	1.1	2.0	2.4	1.8	2.4	2.4	2.4	-0.7	2.5	2.5	2.4	-0.5
Illnesses of father: None of the above (group 1)	2.8	3.4	12.7	-1.1	-1.8	-1.5	-1.7	-1.5	-1.5	-0.8	-1.5	-2.0	-2.2	-1.8	-1.6	-1.6	-3.6	-1.6	-1.6	-1.7	-2.5
Qualifications: A levels/AS levels or equivalent	2.6	5.8	8.7	1.8	2.3	3.0	2.8	2.5	2.9	0.9	2.7	2.6	2.4	2.4	2.9	2.7	-0.1	2.3	2.9	2.7	1.4
Gout (self-reported)	2.6	3.6	7.4	1.5	2.1	1.8	1.8	1.6	1.9	1.4	1.5	2.1	2.7	1.4	1.9	1.7	2.4	1.9	1.9	2.1	1.9
Health satisfaction	2.6	3.4	7.4	-2.7	-1.9	-1.4	-2.3	-2.5	-1.5	-1.2	-2.2	-1.6	-1.3	-2.5	-1.6	-1.7	1.2	-2.1	-1.7	-1.9	-0.5
Chest pain or discomfort	2.6	3.7	6.2	-0.9	-2.1	-2.0	-2.3	-2.0	-2.0	-2.5	-2.0	-2.1	-0.7	-2.0	-2.0	-2.3	0.7	-2.1	-2.1	-1.9	-1.6
Blood White Count	2.5	18.5	35.4	-4.5	-4.3	-3.6	-5.3	-4.8	-3.8	-6.0	-4.7	-3.9	-5.5	-4.9	-3.8	-3.9	-1.7	-5.0	-3.8	-3.2	-2.6
Type 2 Diabetes (T2D) (2018)	2.5	4.6	7.7	-1.1	-1.7	-2.6	-2.3	-2.4	-2.7	-0.6	-1.9	-2.6	-1.7	-2.4	-2.5	-2.8	-0.7	-2.5	-2.6	-1.7	-2.1
Neck or shoulder pain in last month	2.5	3.6	6.8	0.2	-2.1	-2.4	-1.8	-1.6	-2.4	-0.2	-1.7	-2.6	-1.1	-1.1	-2.5	-2.6	-0.5	-2.2	-2.5	-2.3	-0.6
Blood Platelet Count	2.4	28.3	44.6	-3.2	-6.0	-5.2	-6.7	-6.0	-5.7	-5.5	-5.7	-5.3	-5.6	-5.3	-5.8	-5.0	-0.6	-6.5	-5.7	-5.5	-2.6
Stomach or abdominal pain in last month	2.4	3.0	5.0	-1.2	-2.0	-2.1	-1.7	-1.5	-2.0	0.7	-1.5	-1.8	-1.2	-1.4	-2.2	-2.1	-0.4	-1.9	-2.1	-2.0	-2.2
Knee pain experienced in last month	2.4	3.7	6.8	-1.9	-2.5	-1.8	-2.1	-1.9	-1.9	-0.2	-2.0	-2.3	-1.7	-1.8	-2.0	-2.3	-0.5	-2.2	-1.9	-2.6	-1.2
Supplements: Calcium	2.4	2.7	4.6	-1.8	-1.5	-1.5	-1.8	-1.9	-1.4	-0.6	-2.0	-1.4	-2.2	-1.9	-1.5	-1.6	-1.0	-1.7	-1.5	-1.5	-2.0
Glaucoma (self-reported)	2.3	2.7	4.0	1.6	1.9	1.7	1.7	1.9	1.6	-0.3	1.6	1.6	1.9	1.9	1.6	1.7	2.0	1.8	1.5	1.8	0.8
Commuting to job workplace: Car/motor vehicle	2.3	2.6	5.5	-0.6	-1.7	-2.2	-1.1	-1.5	-1.7	1.4	-1.4	-2.0	-1.1	-1.9	-1.8	-2.3	-1.1	-1.7	-1.7	-1.4	-1.6
Number of treatments/medications taken	2.2	3.9	6.0	-2.1	-1.9	-2.3	-2.0	-2.0	-2.0	0.5	-2.4	-2.2	-1.0	-1.9	-2.1	-2.4	1.1	-1.8	-2.0	-2.2	-2.4
Medication: Metformin	2.2	3.1	5.0	-0.6	-1.7	-2.1	-1.9	-1.6	-2.2	-1.1	-1.3	-2.1	-1.4	-1.6	-2.2	-1.9	-0.9	-2.0	-2.2	-1.7	-1.8
Medication: Ramipril	2.2	2.8	5.4	-0.2	-1.5	-1.9	-1.6	-1.9	-1.8	0.8	-1.9	-1.7	-1.9	-1.8	-1.8	-2.0	-0.5	-1.9	-1.8	-1.3	-2.3
Diabetes (self-reported)	2.1	3.2	6.2	0.3	-1.3	-2.4	-1.8	-1.8	-2.4	-0.1	-1.3	-2.0	-1.9	-1.9	-2.2	-2.0	-1.2	-2.0	-2.5	-1.2	-1.7
Headache pain in last month	2.1	3.6	7.6	-1.2	-2.4	-2.1	-1.7	-1.5	-2.4	-0.9	-1.6	-2.6	-0.5	-0.8	-2.5	-2.4	0.2	-2.0	-2.7	-2.8	-1.1
Prostate Cancer	2.0	2.8	5.7	-2.4	-1.9	-1.0	-1.9	-2.2	-1.1	-1.8	-1.9	-1.3	-1.8	-2.3	-1.2	-1.5	0.3	-1.9	-1.3	-1.9	-0.2
Leg pain on walking	2.0	2.5	5.0	-1.5	-1.5	-1.8	-1.3	-1.2	-1.4	-1.2	-0.9	-2.1	-2.2	-1.8	-1.5	-1.8	-0.6	-1.4	-1.7	-1.7	-2.2
Diabetes diagnosed by doctor	1.9	3.1	5.2	-0.6	-1.2	-2.1	-1.9	-2.0	-2.1	-0.1	-1.6	-1.7	-1.7	-2.2	-2.0	-2.0	-0.4	-1.9	-2.2	-1.0	-2.3
Intelligence (Savage-Jansen 2018)	1.8	5.6	9.3	1.6	2.7	2.9	2.5	2.3	2.4	0.1	2.3	2.6	3.1	2.5	2.6	2.4	0.5	2.4	2.3	2.5	2.8
Angina (self-reported)	1.8	2.4	3.9	-1.4	-2.0	-1.7	-1.6	-1.2	-1.6	-1.4	-1.6	-1.8	-1.1	-1.2	-1.7	-1.7	-0.1	-1.8	-1.7	-1.8	-1.4
Heart disease (mother)	1.8	2.2	4.1	-1.2	-1.8	-1.4	-1.7	-1.8	-1.5	-0.8	-1.5	-1.6	-1.4	-1.8	-1.6	-1.6	0.3	-2.0	-1.4	-1.6	-0.9
Medication: Aspirin	1.8	2.3	4.4	-1.2	-1.2	-2.0	-1.5	-1.5	-1.8	-1.0	-1.3	-2.1	-1.2	-1.6	-1.7	-2.0	0.3	-1.4	-2.0	-1.5	-1.3
Medication: Aspirin	1.8	2.4	4.9	-1.3	-1.3	-1.9	-1.4	-1.5	-1.8	-0.6	-1.3	-2.2	-1.1	-1.6	-1.7	-2.2	0.8	-1.3	-1.9	-1.6	-1.1
Commuting to job workplace: Cycle	1.8	2.2	3.8	-0.4	1.7	1.7	1.8	1.5	1.6	-0.8	1.8	1.5	0.4	1.3	1.7	1.6	-0.4	1.9	1.7	1.3	2.0
Vascular/heart problems diagnosed by doctor	1.8	5.0	7.5	1.2	2.3	2.4	2.7	2.4	2.7	1.3	2.6	2.3	1.9	1.7	2.7	2.4	-1.3	2.6	2.7	2.2	1.4
Heart attack/myocardial infarction (self-reported)	1.8	2.4	8.6	-2.9	-1.5	-1.8	-1.6	-1.4	-1.3	-0.6	-1.4	-1.7	-0.9	-1.9	-1.3	-1.7	0.1	-1.5	-1.3	-1.4	-1.5
Alzheimer’s Disease (in mother)	1.7	2.0	5.1	-1.1	-1.8	-1.3	-1.6	-1.5	-1.5	-2.3	-1.3	-1.3	-1.4	-1.1	-1.5	-1.1	0.1	-1.7	-1.5	-1.6	-0.2
Heel T-Score	1.7	13.6	31.9	3.8	3.5	3.4	4.1	3.6	3.5	3.3	3.3	3.3	3.7	3.7	3.6	3.2	5.7	3.7	3.6	3.3	3.2
Sensitivity / hurt feelings	1.7	3.0	11.3	-1.4	-1.4	-1.6	-1.5	-1.1	-1.3	-0.2	-1.3	-1.5	-2.8	-1.8	-1.4	-1.6	-2.4	-1.3	-1.4	-1.2	-3.4
Angina	1.7	2.2	3.5	-1.0	-1.9	-1.7	-1.5	-1.1	-1.5	-1.5	-1.5	-1.8	-1.2	-1.0	-1.6	-1.6	-0.3	-1.7	-1.6	-1.7	-1.4
Current tobacco smoking	1.7	2.7	4.0	0.4	1.9	1.8	1.7	1.3	1.7	1.7	1.6	1.9	1.9	1.2	1.8	1.8	0.3	1.8	1.9	1.9	2.0
Mouth/teeth dental problems: Dentures	1.7	2.8	5.8	-1.4	-1.5	-1.6	-1.8	-1.8	-1.5	-1.7	-1.9	-1.6	-2.4	-2.3	-1.4	-1.9	0.0	-1.6	-1.5	-1.6	-1.6
Suffer from ‘nerves’	1.7	2.6	4.2	1.4	1.9	2.0	1.7	1.6	2.0	0.2	1.6	1.5	1.6	1.4	2.0	1.5	1.6	1.8	1.8	1.8	0.3
Fed-up feelings	1.6	2.9	6.7	-0.0	1.6	2.6	1.4	1.4	2.5	0.9	1.0	2.0	2.1	1.2	2.3	2.0	0.5	2.1	2.4	1.2	0.3
Pulse wave peak to peak time	1.6	1.9	4.4	1.5	1.4	1.1	1.9	1.7	1.2	2.1	1.6	1.0	1.7	1.7	1.2	1.1	-0.3	1.6	1.2	1.2	0.4
Eye problems/disorders: None of the above	1.6	1.9	5.3	1.1	1.4	1.3	1.6	1.2	1.2	2.3	1.3	1.3	1.3	1.4	1.2	1.3	-1.1	1.2	1.3	1.4	1.3
Osteoporosis (self-reported)	1.6	1.9	8.0	-2.8	-0.8	-1.1	-1.2	-1.4	-1.1	-2.2	-1.4	-1.1	-1.3	-1.3	-1.1	-1.5	1.4	-1.2	-1.0	-1.0	0.3
Smoking status: Current	1.6	2.5	3.9	0.2	1.7	1.7	1.7	1.3	1.6	1.6	1.5	1.9	2.0	1.2	1.7	1.7	0.2	1.7	1.9	1.8	1.6
Ulcerative Colitis (UC)	1.5	2.7	9.6	-2.0	-1.8	-1.3	-1.6	-1.1	-1.4	-3.1	-1.3	-1.2	-2.6	-1.0	-1.5	-0.9	-0.8	-1.8	-1.3	-1.8	-1.5
Ever had hysterectomy (womb removed)	1.5	1.7	2.8	-0.2	-1.5	-1.6	-1.2	-1.1	-1.6	-0.5	-1.4	-1.5	-1.5	-0.8	-1.7	-1.2	-1.0	-1.3	-1.6	-1.5	-1.5
Overall health rating	1.5	3.2	7.2	-2.7	-1.3	-1.8	-2.3	-2.4	-1.5	-1.1	-2.3	-1.5	-1.0	-2.5	-1.5	-1.9	1.1	-1.8	-1.7	-1.3	-1.2
Forced expiratory volume in 1-second (FEV1), predicted	1.5	3.2	6.1	2.2	2.2	1.6	2.3	1.7	1.7	2.5	1.9	1.4	1.4	1.6	1.7	1.3	-1.1	2.2	1.6	1.9	0.8
Pack years of smoking	1.5	2.3	5.4	-1.3	-1.8	-1.3	-1.6	-1.4	-1.3	0.2	-1.2	-1.8	-2.3	-1.4	-1.3	-1.6	-1.4	-1.6	-1.3	-1.8	-1.1
Heel bone mineral density (BMD) T-score, automated (left)	1.4	3.3	9.2	1.9	1.8	1.7	1.5	1.8	1.6	1.1	1.5	1.9	1.4	2.5	1.6	1.9	3.0	1.7	1.7	1.9	1.3
Qualifications: CSEs or equivalent	1.4	1.8	4.6	0.1	-1.0	-1.7	-1.1	-1.3	-1.4	1.4	-1.2	-1.6	-1.5	-1.3	-1.4	-1.8	-0.6	-1.2	-1.4	-1.0	-2.2
Alcohol usually taken with meals	1.4	2.3	5.2	2.3	2.0	1.8	1.2	1.2	1.4	0.1	1.3	1.7	1.6	1.4	1.5	1.6	0.4	1.7	1.4	2.0	1.1
Time employed in main current job	1.4	1.6	2.6	-1.3	-1.1	-1.4	-1.6	-1.6	-1.3	-1.1	-1.6	-1.0	-0.5	-1.5	-1.3	-1.1	1.3	-1.5	-1.3	-0.9	-1.1
Noisy workplace	1.4	1.7	5.1	-0.6	-0.8	-1.5	-1.2	-1.4	-1.3	-0.1	-1.3	-1.3	-1.1	-1.6	-1.3	-1.3	-2.3	-1.1	-1.3	-0.8	-1.6
Commuting to job workplace: Walk	1.4	1.5	4.0	2.0	1.1	1.1	1.5	1.7	1.2	-0.3	1.5	1.0	0.6	1.9	1.1	1.4	-0.1	1.3	1.0	1.3	0.3
Mouth/teeth dental problems: Mouth ulcers	1.4	2.2	5.1	-0.4	-1.2	-2.3	-1.4	-1.1	-2.1	0.5	-1.1	-1.8	-1.0	-1.1	-2.0	-2.0	-0.6	-1.5	-2.1	-1.3	-1.2
Alcohol drinker status: Previous	1.4	1.6	4.8	-0.4	-1.0	-1.1	-1.4	-1.8	-1.1	-1.3	-1.9	-0.9	-2.2	-1.5	-1.3	-0.9	0.3	-1.2	-1.3	-0.9	-0.9
Medication for hormone replacement therapy	1.3	1.5	10.0	0.4	-1.1	-0.4	-1.3	-0.6	-0.8	-3.2	-0.9	-1.1	-1.9	-0.3	-0.8	-0.4	-1.2	-0.9	-0.7	-1.1	-1.3
Heart attack	1.3	1.6	6.6	-2.6	-1.2	-1.5	-1.3	-1.1	-1.1	-0.6	-1.1	-1.5	-0.6	-1.5	-1.0	-1.5	0.3	-1.2	-1.1	-1.1	-1.2
Hypothyroidism/myxoedema (self-reported)	1.3	2.5	4.8	-1.2	-1.9	-1.4	-1.6	-1.8	-1.3	0.0	-2.2	-1.5	-1.4	-2.0	-1.4	-1.8	0.5	-1.9	-1.4	-1.7	-1.9
Loneliness, isolation	1.3	1.8	3.3	1.2	1.6	1.3	1.7	1.7	1.5	1.0	1.5	1.1	1.0	1.3	1.4	0.9	-0.8	1.8	1.6	1.3	0.6
Guilty feelings	1.3	2.0	4.9	1.8	1.1	1.3	1.8	1.8	1.1	2.2	1.8	0.9	0.8	1.9	1.1	1.1	-1.5	1.6	1.1	0.8	-0.5
Pain type(s) experienced in last month: Hip pain	1.3	1.6	3.7	-0.2	-1.2	-1.9	-1.0	-1.1	-1.6	1.1	-0.9	-1.6	-0.7	-1.3	-1.5	-1.9	-0.1	-1.1	-1.4	-1.3	-1.1
Ovarian Cancer	1.2	1.6	3.8	0.7	1.2	1.0	1.6	1.7	1.1	0.8	1.5	1.1	-0.1	1.7	1.1	1.3	-1.9	1.4	1.3	1.1	0.1
Hayfever, allergic rhinitis or eczema	1.2	2.6	5.5	1.8	2.0	1.1	1.7	1.8	1.0	0.1	2.0	1.5	1.7	2.0	1.2	1.6	0.6	1.8	1.2	1.6	2.4
Pulse wave Arterial Stiffness index	1.2	1.4	3.7	-1.5	-1.2	-0.7	-1.7	-1.5	-0.8	-1.9	-1.4	-0.6	-1.3	-1.6	-0.8	-0.8	0.2	-1.3	-0.8	-0.9	-0.3
Breastfed as a baby	1.2	1.4	2.9	1.7	1.3	1.3	1.3	1.4	1.1	-0.1	1.4	1.0	1.3	1.4	1.2	1.3	-0.1	1.3	1.2	1.1	0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	1.2	1.8	4.3	2.1	1.4	1.0	1.4	1.7	1.2	1.3	1.4	1.1	1.2	1.5	1.2	1.3	0.8	1.8	1.3	1.1	0.4
Medication: Gliclazide	1.2	1.3	2.8	-1.3	-1.1	-1.5	-1.0	-1.1	-1.3	-0.7	-0.7	-1.5	-0.6	-1.3	-1.3	-1.7	-0.4	-1.2	-1.4	-1.2	-0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.2	2.5	5.4	-0.8	-2.2	-1.7	-1.5	-0.9	-1.8	-1.5	-1.2	-1.9	-1.3	-0.6	-1.9	-1.4	-1.2	-1.6	-1.7	-2.3	-1.6
Risk taking	1.2	1.7	4.9	1.8	1.1	1.0	1.5	1.8	0.9	0.9	1.4	1.1	1.6	2.2	0.9	1.4	-0.3	1.3	0.9	1.2	0.7
High blood pressure	1.1	3.2	5.5	-0.7	-1.7	-2.1	-2.1	-1.9	-2.4	-1.1	-2.0	-1.8	-1.6	-1.3	-2.3	-1.9	1.4	-2.0	-2.3	-1.6	-0.9
Heel bone mineral density (BMD) T-score, automated (right)	1.1	2.6	7.2	1.8	1.6	1.3	1.4	1.7	1.2	0.8	1.4	1.6	1.2	2.5	1.2	1.7	2.7	1.5	1.2	1.6	1.3
Ever unenthusiastic/disinterested for a whole week	1.1	1.3	2.7	1.3	1.6	1.0	1.2	1.0	1.1	0.9	1.1	1.2	0.7	1.1	1.1	1.4	0.4	1.4	1.1	1.5	1.0
Comparative body size at age 10	1.1	3.0	6.1	-0.2	-1.9	-2.2	-1.6	-2.0	-2.0	0.9	-1.4	-1.8	-2.5	-2.0	-2.0	-1.7	-0.6	-2.1	-2.1	-1.4	-0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	1.1	1.4	2.8	1.7	1.3	1.1	1.4	1.3	1.3	1.6	1.0	1.1	0.5	0.9	1.3	1.1	0.7	1.4	1.5	1.2	0.7
Medication for cholesterol	1.1	1.7	3.8	0.0	1.5	1.1	1.4	1.1	1.4	1.0	1.4	1.0	1.8	0.7	1.5	0.8	1.1	1.6	1.4	1.1	2.0
Financial situation satisfaction	1.1	1.4	2.9	0.3	1.3	1.1	1.5	1.4	1.1	0.1	1.7	1.0	1.5	1.0	1.2	1.3	1.3	1.3	1.0	1.0	0.9
Deep venous thrombosis (DVT) (self-reported)	1.1	1.4	3.4	-1.0	-0.9	-1.4	-0.7	-1.5	-1.4	0.6	-0.8	-1.6	-0.5	-1.6	-1.3	-1.8	0.5	-1.2	-1.4	-1.0	0.2
Type 2 Diabetes (T2D) (2012)	1.0	1.2	6.5	0.9	1.0	1.5	0.8	0.7	1.3	-0.4	0.5	0.5	0.2	0.9	1.4	0.9	1.2	0.8	1.1	1.0	2.6
Hair Pigment	1.0	27.9	36.1	-3.3	-6.0	-5.6	-5.8	-5.5	-5.6	-0.7	-5.8	-5.7	-5.3	-5.7	-5.8	-5.9	-0.1	-5.8	-5.6	-5.8	-5.9
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	5.6	0.2	-0.9	-1.1	-1.2	-0.5	-0.9	-2.4	-0.5	-1.2	-1.4	-0.8	-0.9	-1.0	-0.4	-0.9	-1.0	-0.7	-1.4
Father’s age at death	1.0	1.3	2.6	0.4	1.3	1.5	1.5	0.7	1.4	1.6	0.8	1.0	1.4	0.5	1.4	0.8	0.2	1.5	1.5	0.9	-0.4
Mouth/teeth dental problems: Loose teeth	1.0	1.2	3.1	-0.3	-0.8	-0.9	-1.2	-1.8	-1.1	0.8	-1.4	-0.6	-0.8	-1.7	-1.1	-1.4	0.0	-1.5	-1.3	-0.1	-1.0
Primary Biliary Cirrhosis	0.9	1.2	2.9	-0.6	-0.8	-1.4	-1.1	-1.2	-1.4	0.2	-1.1	-1.1	-0.8	-0.9	-1.4	-1.1	1.7	-1.0	-1.4	-1.3	0.3
Bilateral oophorectomy (both ovaries removed)	0.9	1.0	2.1	-0.3	-1.2	-1.0	-0.9	-0.8	-1.2	-0.4	-0.9	-1.2	-1.4	-0.8	-1.1	-1.1	-1.4	-1.0	-1.1	-1.1	-0.7
Body mass index (BMI)	0.9	4.0	6.7	-1.5	-2.6	-2.3	-2.1	-2.0	-2.1	0.3	-1.9	-2.6	-1.6	-1.6	-2.3	-2.3	0.1	-2.3	-2.4	-2.5	-1.2
Had other major operations	0.9	1.1	2.9	-0.6	-0.9	-0.7	-1.3	-1.5	-0.6	-0.4	-1.7	-0.7	-1.3	-1.6	-0.6	-1.0	-0.5	-0.9	-0.7	-0.6	-1.4
Neuroticism score	0.9	1.9	3.3	1.3	1.5	1.7	1.6	1.5	1.6	1.0	1.4	1.2	0.4	1.4	1.5	1.2	-1.4	1.8	1.5	1.3	-0.6
Blood clot in the leg (DVT)	0.9	1.1	2.7	-0.6	-0.8	-1.3	-0.7	-1.4	-1.3	0.6	-0.8	-1.5	-0.6	-1.4	-1.2	-1.6	0.5	-1.1	-1.3	-0.8	0.3
Had major operations	0.9	1.0	3.1	-0.6	-1.8	-1.0	-0.8	-0.2	-1.2	-0.8	-0.3	-1.0	-1.5	0.0	-1.3	-0.6	0.3	-1.2	-1.1	-1.6	-0.3
Illnesses of father: Heart disease	0.9	1.3	6.9	0.0	1.0	1.1	0.8	0.8	0.9	0.2	0.9	1.0	1.2	1.1	0.9	0.7	2.6	1.0	0.9	0.8	1.8
Asthma (self-reported)	0.9	1.8	4.8	-1.7	-0.6	-1.3	-1.4	-1.4	-1.1	-2.2	-1.4	-1.1	-0.5	-1.7	-1.0	-1.6	2.0	-1.0	-1.3	-0.9	0.0
Miserableness	0.9	1.5	2.9	-0.1	1.4	1.6	1.5	1.2	1.7	1.0	1.1	1.4	0.8	1.0	1.6	1.1	0.2	1.7	1.5	1.1	0.4
Heart disease (siblings)	0.9	1.2	2.2	-0.9	-0.8	-1.2	-1.1	-1.2	-1.1	-1.2	-1.1	-1.1	-1.1	-1.5	-1.1	-1.3	0.7	-1.2	-1.1	-0.7	-0.6
Depression (Nagel 2018)	0.8	1.2	5.7	-1.1	-1.0	-1.1	-0.7	-0.7	-0.9	0.0	-0.8	-1.2	-1.2	-0.9	-1.0	-1.1	-0.8	-0.7	-1.0	-1.4	-2.4
Alzheimer’s Disease (in father)	0.8	0.9	1.8	-0.3	-1.0	-1.0	-1.3	-1.0	-1.1	-0.3	-1.1	-1.2	-0.7	-0.5	-1.1	-0.8	0.3	-1.1	-1.0	-1.2	-0.9
Irritable Bowel Disease (IBD)	0.8	2.0	8.7	-1.8	-1.4	-1.0	-1.3	-0.5	-1.0	-2.9	-0.4	-0.8	-2.7	-0.7	-1.0	-0.4	-1.4	-1.4	-0.9	-1.4	-1.1
Major Depression (MDD)	0.8	0.9	3.0	1.7	1.0	0.9	0.5	0.8	0.7	-1.0	0.6	1.3	-0.5	0.7	0.7	1.4	-0.1	0.8	1.2	1.4	-0.1
Lupus	0.8	1.3	3.8	-1.9	-0.5	-1.2	-1.1	-1.4	-1.1	0.2	-1.4	-1.2	0.1	-1.7	-1.1	-1.4	-0.9	-0.8	-1.1	-0.9	-0.2
Hypothyroidism (self reported)	0.8	1.8	3.4	-0.9	-1.3	-1.4	-1.2	-1.5	-1.1	0.5	-1.8	-1.4	-1.1	-1.7	-1.1	-1.8	0.6	-1.3	-1.2	-1.3	-1.9
Serious illness, injury or assault to yourself	0.8	1.0	1.6	-1.3	-1.0	-1.1	-1.0	-1.2	-1.2	1.1	-1.2	-0.8	0.2	-0.9	-1.2	-1.1	0.6	-1.0	-1.3	-1.0	-0.0
Diverticular disease/diverticulitis (self-reported)	0.8	0.9	3.4	-1.9	-1.2	-0.2	-0.9	-1.2	-0.3	0.1	-1.2	-0.8	-0.3	-1.0	-0.5	-0.8	0.9	-0.7	-0.2	-1.5	-1.1
Impedance of leg (left)	0.8	3.9	7.0	1.4	2.6	1.9	2.3	1.9	1.9	1.4	2.1	2.2	2.0	1.9	2.1	2.1	1.0	2.2	2.0	2.2	2.0
Asthma	0.8	1.7	4.9	-1.6	-0.5	-1.2	-1.3	-1.3	-0.9	-2.1	-1.4	-1.1	-0.2	-1.6	-0.9	-1.5	2.2	-0.9	-1.2	-0.9	-0.0
Lung cancer (father)	0.8	1.0	5.7	-0.4	-0.9	-0.7	-0.7	-0.5	-0.6	-0.3	-0.6	-0.9	-1.8	-0.5	-0.7	-0.5	-2.4	-0.8	-0.7	-0.7	-1.3
Pulse wave reflection index	0.8	1.0	2.0	1.0	1.0	0.9	1.1	1.2	0.9	0.6	1.4	0.9	0.3	1.4	0.9	1.1	0.2	0.9	0.9	0.9	1.4
Qualifications: O levels/GCSEs or equivalent	0.8	1.3	2.8	0.9	1.1	1.3	1.3	1.3	1.0	0.7	1.1	1.1	1.5	1.7	1.0	1.2	-0.8	1.3	1.0	0.9	0.5
Medication for cholesterol, blood pressure or diabetes	0.8	1.3	2.6	1.0	0.6	1.6	1.2	1.1	1.6	1.2	0.9	1.2	0.4	1.0	1.5	1.5	-1.3	1.0	1.6	0.5	0.2
Medication: Allopurinol	0.8	1.1	3.7	0.9	0.9	0.7	1.0	1.2	0.9	1.0	0.7	1.0	1.7	0.8	0.9	0.8	1.9	1.0	1.0	1.0	0.4
Hypertension (Self-reported)	0.8	2.3	4.0	-0.7	-1.4	-1.6	-1.8	-1.6	-2.0	-0.9	-1.8	-1.5	-1.3	-1.2	-1.9	-1.6	1.3	-1.7	-1.9	-1.3	-0.8
Average weekly champagne plus white wine intake	0.8	1.0	2.3	1.2	0.9	1.1	0.9	0.8	1.0	0.9	0.8	1.4	1.2	1.2	0.9	1.5	-0.8	1.0	1.0	0.9	-0.2
Medication: Omeprazole (e.g. Zanprol)	0.8	1.0	1.9	0.8	-0.9	-1.0	-1.0	-0.8	-1.4	0.8	-1.2	-1.1	-0.8	-0.1	-1.4	-0.9	-0.8	-1.0	-1.3	-1.0	-1.0
BMI	0.7	4.3	7.5	-2.0	-2.6	-2.3	-2.3	-2.0	-2.2	-0.3	-2.0	-2.7	-1.2	-1.6	-2.4	-2.6	0.5	-2.4	-2.4	-2.4	-1.1
Ever used hormone-replacement therapy (HRT)	0.7	0.9	2.2	-0.6	-1.0	-0.5	-1.2	-1.2	-0.6	-0.4	-1.5	-0.7	-1.3	-1.0	-0.7	-0.7	-0.3	-0.9	-0.7	-1.1	-1.3
Severe depression (siblings)	0.7	0.8	1.4	-0.8	-0.9	-0.4	-1.0	-1.2	-0.6	-0.3	-1.0	-0.9	-0.8	-1.2	-0.7	-0.9	-1.0	-1.0	-0.9	-0.7	-1.2
Impedance of leg (right)	0.7	3.4	5.7	1.4	2.4	1.9	2.2	1.8	1.8	1.2	2.0	2.0	2.0	1.9	1.9	1.9	0.6	2.1	1.9	1.8	1.7
Arm fat percentage (right)	0.7	2.7	5.0	-1.5	-2.1	-1.8	-1.8	-1.6	-1.7	0.1	-1.6	-2.1	-0.7	-1.2	-1.8	-1.9	0.9	-1.9	-2.0	-2.2	-0.1
Medication: Blood pressure	0.7	1.2	1.8	-0.7	-0.8	-1.2	-1.3	-1.1	-1.3	-1.4	-1.1	-1.2	-0.8	-0.7	-1.3	-1.3	0.9	-0.9	-1.3	-0.9	-0.8
Medication: Omeprazole	0.7	0.8	1.6	0.5	-0.9	-0.9	-1.0	-0.6	-1.3	0.4	-1.1	-1.0	-0.7	-0.2	-1.2	-0.9	-0.9	-0.9	-1.2	-0.9	-0.7
Alcohol intake frequency.	0.7	1.6	3.2	0.1	-1.1	-1.6	-1.5	-1.2	-1.6	-1.5	-1.1	-1.2	-1.8	-0.8	-1.7	-1.0	-0.2	-1.3	-1.7	-1.1	-1.0
Mother’s age at death	0.7	0.9	3.1	-1.8	0.7	1.3	0.5	0.6	1.1	-0.9	0.5	1.3	0.6	1.1	1.0	1.1	0.3	0.9	1.1	0.5	0.5
Age started oral contraceptive pill	0.7	0.9	4.8	-1.1	-1.1	-0.2	-1.0	-0.8	-0.6	-2.2	-0.8	-0.5	-0.9	-0.6	-0.7	-0.4	0.9	-1.1	-0.6	-0.9	-0.9
Impedance of whole body	0.7	3.3	5.7	1.4	2.2	1.8	1.9	1.7	1.7	1.1	1.8	2.0	2.0	1.8	1.9	2.0	1.0	2.0	1.8	1.7	2.4
LDL Cholesterol	0.6	0.9	1.7	-0.1	0.9	1.2	0.5	0.7	1.2	-0.8	0.7	1.3	0.9	0.7	1.2	1.0	0.6	0.8	1.3	1.2	0.9
Allergy or Eczema	0.6	1.6	4.0	1.9	1.7	0.8	1.3	1.2	0.7	0.5	1.2	1.2	1.0	1.5	0.9	1.2	-0.1	1.6	0.8	1.5	2.0
Cardiovascular Disease	0.6	1.8	3.5	-1.1	-0.9	-1.8	-1.4	-1.4	-1.9	-0.4	-1.3	-1.3	-0.3	-1.2	-1.8	-1.7	1.7	-1.4	-1.8	-0.7	-0.4
Age when periods started (menarche)	0.6	1.4	3.9	-0.7	1.0	1.1	0.6	0.8	1.2	-0.5	0.8	1.8	2.0	0.8	1.1	1.8	1.9	0.9	1.4	1.1	0.5
Supplements: Glucosamine	0.6	0.8	2.1	0.9	0.5	0.5	1.4	1.2	0.7	1.4	1.2	-0.2	1.0	1.1	0.7	0.3	-1.0	1.1	0.6	-0.1	0.7
Nervous feelings	0.6	1.0	2.8	-0.2	1.1	1.7	0.9	0.7	1.5	0.1	0.6	1.1	0.7	0.8	1.4	0.9	0.9	1.3	1.4	1.0	0.1
Had menopause	0.6	0.7	2.4	1.5	1.0	0.9	0.5	0.5	0.7	-1.1	0.5	0.6	-0.4	0.7	0.8	1.1	-0.3	0.9	0.7	0.7	1.2
Medication: Lansoprazole	0.6	0.7	1.0	0.1	-0.9	-1.0	-0.9	-0.8	-0.9	0.4	-1.0	-0.9	-0.4	-1.0	-0.9	-0.9	-0.1	-0.9	-0.9	-0.7	-1.0
Illnesses of mother	0.6	0.8	6.3	0.4	0.2	-0.0	0.5	0.9	0.2	0.4	0.2	-0.2	-0.3	0.7	0.1	0.2	-2.5	0.5	0.0	-0.0	-2.4
Peak expiratory flow (PEF)	0.6	1.5	3.0	-0.8	-1.6	-0.8	-1.4	-1.3	-0.9	-0.0	-1.7	-1.1	-0.9	-1.2	-1.0	-1.3	-1.6	-1.4	-1.0	-1.4	-1.4
Birth weight	0.6	1.4	3.8	0.1	-1.3	-1.2	-0.6	-0.2	-1.4	-1.7	-0.4	-1.4	-1.0	0.5	-1.5	-0.9	-1.1	-1.0	-1.4	-1.4	-1.9
Medication: Ibuprofen	0.6	0.8	7.2	-1.1	0.1	0.1	0.6	0.1	0.2	2.7	0.3	0.4	1.6	0.1	0.1	0.2	0.7	0.2	0.3	0.0	1.3
Pulse rate, automated reading	0.6	1.9	6.1	0.2	1.4	1.2	1.0	1.5	1.2	-1.5	1.3	1.7	2.5	1.4	1.2	1.9	0.8	1.3	1.3	1.6	0.8
Illness, injury, bereavement, stress in last 2 years	0.6	0.7	4.7	-1.5	-0.5	-0.2	-0.8	-0.7	-0.0	-2.2	-0.7	-0.7	-0.5	-1.0	-0.0	-0.6	1.1	-0.6	-0.3	-0.6	-0.2
Handedness (chirality/laterality): Left-handed	0.6	0.7	1.7	0.1	0.6	0.8	0.8	1.3	0.8	-1.3	0.8	0.9	0.3	1.2	0.7	1.1	-0.3	1.0	0.9	0.5	1.0
Medication: Paracetamol	0.6	0.9	3.1	-0.3	-0.9	-1.3	-0.0	0.1	-1.3	1.8	-0.3	-1.2	-0.3	0.2	-1.4	-1.2	-0.4	-0.6	-1.3	-1.3	-0.4
Alcohol drinker status: Never	0.6	0.7	2.7	-0.4	-0.9	-0.7	-1.1	-0.7	-0.6	-1.6	-0.8	-0.8	-0.2	-0.6	-0.8	-0.5	1.0	-0.7	-0.8	-1.0	-1.3
Irritability	0.6	1.1	3.3	-0.7	0.7	1.5	1.3	1.1	1.2	-0.2	1.1	0.9	1.8	0.9	1.2	0.9	-0.7	0.8	1.2	0.7	0.4
Unable to work because of sickness or disability	0.6	0.8	2.2	-1.5	-1.1	-0.8	-1.2	-1.2	-0.7	-0.0	-1.0	-0.5	-0.6	-1.1	-0.9	-0.7	0.2	-1.1	-0.8	-0.6	-1.2
Breast Cancer	0.5	1.3	3.1	1.2	0.8	1.8	1.0	0.9	1.5	1.6	0.5	1.0	1.2	1.2	1.4	1.1	0.4	1.2	1.4	0.3	0.4
Body Mass Index (BMI) (2010)	0.5	0.7	1.6	0.7	0.8	1.1	0.7	0.5	1.2	1.0	0.3	1.0	0.5	0.6	1.1	0.7	-0.0	0.9	1.0	1.3	-0.2
Crohns Disease (2012)	0.5	0.8	3.1	-1.8	-0.7	-0.8	-1.0	-0.7	-0.7	-0.4	-0.7	-0.7	-1.3	-1.2	-0.6	-0.9	-0.2	-0.8	-0.7	-0.8	-0.9
Ulcerative Colitis	0.5	0.7	3.4	-0.9	-1.1	-0.7	-0.1	0.4	-0.8	-1.4	0.1	-0.5	-1.8	0.4	-0.9	0.1	0.3	-0.7	-0.7	-1.0	-0.7
Smoking Status	0.5	1.3	2.2	0.1	0.9	1.4	1.2	1.4	1.3	0.2	1.5	1.2	1.5	1.2	1.3	1.2	-0.9	1.1	1.3	1.1	0.5
Pack years adult smoking proportion	0.5	0.8	2.6	-0.6	-1.0	-0.8	-0.9	-0.6	-0.8	0.8	-0.4	-1.2	-1.6	-0.5	-0.8	-1.0	-1.0	-0.9	-0.8	-1.0	-0.7
High blood pressure (mother)	0.5	0.7	4.6	0.9	0.6	0.3	0.3	-0.3	0.2	1.7	0.1	0.5	0.7	-0.1	0.3	0.1	2.1	0.4	0.4	0.5	1.5
Waist circumference	0.5	2.0	3.4	-1.9	-1.7	-1.5	-1.6	-1.5	-1.3	-0.1	-1.3	-1.8	-0.8	-1.4	-1.4	-1.7	0.1	-1.6	-1.5	-1.7	-0.4
Alcohol intake versus 10 years previously	0.5	0.7	1.9	0.6	-0.0	-1.2	-0.7	-0.5	-1.4	-1.0	-0.2	-0.8	-0.2	-0.6	-1.1	-0.8	0.8	-0.4	-1.3	-0.4	1.0
Hair/balding pattern: Pattern 3	0.5	0.7	2.4	0.3	-0.7	-1.1	0.3	0.5	-1.0	0.6	0.6	-1.6	-0.3	0.2	-1.0	-1.1	-0.5	-0.3	-1.0	-1.1	-1.1
Number of live births	0.5	0.7	3.9	0.9	-0.2	-0.5	-0.5	-0.1	-0.4	-1.9	-0.1	-0.2	-1.4	-0.2	-0.4	-0.3	-2.0	-0.5	-0.4	0.0	-0.7
Pulse rate	0.5	0.9	3.2	-1.8	-0.9	-0.7	-0.9	-1.0	-0.7	-1.7	-0.9	-0.6	0.4	-1.3	-0.7	-0.8	0.9	-1.0	-0.6	-0.6	-0.5
Impedance of arm (left)	0.5	2.4	7.0	1.1	1.7	1.5	1.4	1.5	1.4	0.5	1.6	1.6	1.9	1.6	1.6	1.7	0.7	1.6	1.5	1.2	2.6
Arm fat mass (right)	0.5	2.2	4.2	-1.5	-2.0	-1.6	-1.5	-1.6	-1.4	0.7	-1.5	-2.0	-0.6	-1.3	-1.5	-1.9	0.8	-1.7	-1.7	-2.1	-0.4
Exposure to tobacco smoke at home	0.5	0.5	1.9	-0.9	-0.4	-0.8	-0.3	-0.3	-0.9	-0.5	-0.2	-1.1	-0.4	-0.2	-0.9	-1.0	-1.4	-0.3	-0.9	-0.6	-0.6
Loud music exposure frequency	0.5	0.6	1.4	-1.1	-0.8	-0.7	-1.0	-1.0	-0.8	-0.1	-0.9	-0.5	-0.1	-0.8	-0.9	-0.4	0.3	-1.2	-0.9	-0.5	-0.1
Leg fat percentage (right)	0.5	1.8	3.4	-1.4	-1.6	-1.5	-1.4	-1.3	-1.4	0.5	-1.1	-1.7	-0.8	-0.9	-1.5	-1.5	0.6	-1.5	-1.6	-1.8	-0.0
Worry too long after embarrassment	0.5	0.8	5.2	1.4	0.1	0.2	0.7	0.7	0.2	1.3	0.6	-0.2	-0.9	0.5	0.1	0.3	-2.3	0.4	0.2	0.0	-1.6
Supplements: Vitamin C	0.5	0.6	4.8	0.4	-0.1	-0.6	0.5	0.6	-0.4	-0.8	0.7	-0.8	-1.2	-0.0	-0.3	-0.3	-2.2	0.1	-0.2	-0.0	-1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.5	4.3	2.1	0.3	0.4	0.0	0.3	0.2	0.4	-0.3	0.5	-0.4	0.5	0.2	0.6	-1.8	0.6	0.3	0.1	-0.6
Arm fat percentage (left)	0.5	2.1	4.0	-1.4	-1.8	-1.6	-1.6	-1.5	-1.5	0.2	-1.3	-1.9	-0.5	-1.0	-1.6	-1.6	1.0	-1.7	-1.8	-2.0	0.3
Arm fat mass (left)	0.5	1.9	3.5	-1.3	-1.8	-1.4	-1.4	-1.5	-1.3	0.7	-1.3	-1.8	-0.3	-1.2	-1.4	-1.6	0.9	-1.6	-1.5	-1.9	-0.1
Ever had prostate specific antigen (PSA) test	0.5	0.5	1.4	0.4	0.7	1.2	0.7	0.5	0.8	-0.4	0.8	0.9	0.3	0.5	0.8	0.8	-0.4	0.6	0.8	1.0	0.8
Basal cell carcinoma (self-reported)	0.5	0.5	1.2	0.4	0.7	1.1	0.6	0.3	1.1	0.3	0.3	1.1	0.4	-0.0	1.0	1.0	-0.9	0.8	1.0	0.7	0.0
Fasting Glucose	0.4	0.4	3.1	0.7	-0.6	-0.3	-0.3	-0.6	-0.2	1.8	-1.0	-0.5	-0.8	-0.4	-0.4	-0.3	0.1	-0.6	-0.2	-0.5	-0.6
Vitamin and mineral supplements	0.4	0.6	3.9	-0.0	0.6	0.5	0.4	0.4	0.5	0.6	0.5	1.0	1.0	0.4	0.5	0.9	2.0	0.3	0.5	0.6	0.8
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	2.1	-0.7	-0.3	-0.9	-0.4	-0.2	-0.9	0.7	-0.2	-0.7	-1.0	-0.5	-0.9	-0.6	0.6	-0.3	-0.9	-0.5	-1.4
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	2.0	0.1	1.1	0.3	1.2	1.3	0.2	0.9	1.4	0.4	0.2	1.2	0.3	0.5	-0.2	1.0	0.2	0.8	0.5
Allergy	0.4	0.9	3.1	-0.7	-1.4	-0.5	-0.9	-0.8	-0.5	0.8	-0.9	-0.7	-1.4	-0.8	-0.7	-0.7	-1.4	-1.1	-0.5	-1.0	-1.8
Falls in the last year	0.4	0.6	1.3	1.1	0.6	0.4	1.0	1.1	0.6	0.6	0.7	0.7	-0.8	1.1	0.5	1.0	0.4	0.9	0.5	0.6	0.3
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	4.9	-1.1	-0.2	0.0	0.3	-0.2	0.1	2.2	-0.0	0.3	1.0	-0.1	-0.0	0.1	0.5	-0.1	0.1	-0.1	1.2
Birth weight of first child	0.4	0.8	1.6	-0.5	-0.9	-1.0	-0.8	-0.9	-0.9	0.8	-1.0	-1.2	-0.6	-0.8	-0.9	-1.0	-0.9	-0.7	-1.3	-1.0	-0.7
Medication: Paracetamol	0.4	0.6	1.6	-0.4	-1.0	-0.9	-0.1	0.1	-1.0	1.1	-0.3	-1.1	-0.3	0.3	-1.1	-1.0	-0.4	-0.5	-1.1	-1.3	-0.5
Medication: Ventolin 100micrograms inhaler	0.4	0.5	2.2	-0.4	0.9	0.3	0.8	0.5	0.4	-0.7	0.8	0.5	1.5	0.2	0.5	0.3	1.2	0.7	0.4	1.1	0.3
Chronic bronchitis/emphysema (mother)	0.4	0.4	1.8	-1.2	-0.5	-0.6	-0.5	-0.6	-0.3	0.2	-0.5	-0.7	-0.2	-1.4	-0.2	-0.9	1.0	-0.6	-0.2	-0.3	-0.6
Shortness of breath walking on level ground	0.4	0.4	2.9	-0.5	-0.1	0.0	-0.7	-1.2	-0.3	-0.5	-0.6	0.1	-0.2	-1.2	-0.2	-0.0	1.7	-0.7	-0.4	0.1	0.3
Mean time to correctly identify matches	0.4	0.8	4.4	-0.3	-0.5	-0.9	-0.8	-0.6	-1.1	-2.1	-0.2	-1.2	-0.1	-0.6	-0.9	-0.8	1.0	-0.8	-1.1	-0.6	0.1
Leg fat mass (right)	0.4	1.6	3.5	-1.4	-1.7	-1.4	-1.2	-1.3	-1.2	1.0	-1.0	-1.7	-0.5	-1.0	-1.3	-1.5	0.7	-1.3	-1.4	-1.9	-0.3
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	1.4	0.2	-0.8	-0.7	-0.3	-0.3	-0.7	-0.7	-0.1	-0.9	-1.1	-0.1	-0.8	-0.8	0.8	-0.4	-0.8	-1.2	0.3
Osteoarthritis (self-reported)	0.4	0.6	5.4	0.7	0.2	0.2	0.8	0.6	0.3	2.3	0.7	0.2	0.6	0.9	0.3	0.2	0.6	0.4	0.5	-0.1	0.8
Commuting to job workplace: Public transport	0.4	0.4	2.4	-0.2	0.5	0.5	0.2	0.7	0.5	-1.6	0.7	0.3	-0.1	0.6	0.7	0.5	0.5	0.3	0.6	0.7	1.2
Medication: Blood pressure	0.4	0.7	1.6	-0.2	-0.8	-0.8	-0.9	-1.0	-0.8	0.7	-1.0	-0.6	-1.3	-1.0	-0.9	-0.7	-0.8	-1.0	-0.8	-0.6	-1.2
Leg fat percentage (left)	0.4	1.5	2.6	-1.4	-1.5	-1.4	-1.3	-1.2	-1.3	0.4	-1.0	-1.6	-0.8	-0.8	-1.4	-1.4	0.8	-1.4	-1.5	-1.6	-0.0
Leg fat mass (left)	0.4	1.5	3.2	-1.4	-1.6	-1.3	-1.1	-1.2	-1.2	0.8	-1.0	-1.7	-0.6	-0.9	-1.3	-1.5	0.7	-1.3	-1.4	-1.8	-0.2
Crohns Disease (2017)	0.3	0.8	4.0	-1.2	-0.5	-0.4	-0.9	-0.4	-0.3	-1.3	-0.0	-0.2	-2.0	-0.8	-0.3	-0.2	-1.7	-0.7	-0.3	-0.5	-0.9
Mean Putamen Volume	0.3	0.3	0.7	0.1	0.8	0.8	0.2	0.1	0.6	-0.8	0.3	0.3	0.5	0.2	0.7	0.2	-0.3	0.7	0.5	0.5	-0.9
HbA1C	0.3	0.4	5.1	-0.2	-0.2	0.3	0.2	-0.0	0.3	2.3	-0.1	0.1	0.6	0.3	0.1	0.0	0.7	-0.0	0.5	0.3	-0.2
HDL Cholesterol	0.3	0.5	1.5	-0.6	-0.5	-0.6	-0.8	-1.2	-0.7	-0.4	-0.3	-0.5	-1.0	-0.8	-0.7	-0.5	0.0	-0.7	-0.8	-0.5	0.5
Systolic Blood Pressure	0.3	1.5	7.8	0.6	1.2	0.4	0.2	0.3	0.4	-0.2	0.8	1.2	2.6	0.8	0.6	0.9	2.0	0.6	0.5	1.1	2.8
Respiratory disease	0.3	0.6	3.5	-1.5	0.1	-0.3	-0.5	-0.4	-0.0	-1.9	-0.6	-0.1	0.6	-0.7	-0.0	-0.4	1.7	-0.3	-0.2	0.1	0.2
Average weekly spirits intake	0.3	0.3	1.7	-1.1	-0.2	0.2	-0.3	-0.5	0.2	1.0	-0.2	-0.1	0.0	-0.7	0.0	-0.2	-0.9	-0.0	0.1	-0.3	-1.3
Systolic blood pressure, automated reading	0.3	1.0	4.2	-0.5	-0.8	-0.6	-1.5	-1.3	-0.7	-2.0	-1.3	-0.5	0.4	-1.0	-0.6	-0.5	0.9	-1.2	-0.8	-0.8	0.9
Hand grip strength (right)	0.3	0.8	2.3	-0.1	-1.0	-0.7	-0.9	-1.2	-0.7	1.0	-1.4	-1.0	0.1	-1.0	-0.8	-1.5	0.2	-0.9	-0.8	-0.8	-0.7
Townsend deprivation index at recruitment	0.3	0.4	3.0	-1.7	-0.1	0.1	-0.0	0.0	0.4	-0.8	-0.0	0.3	0.4	-0.3	0.3	0.2	1.6	-0.1	0.4	-0.0	-0.1
Multivitamins +/- minerals	0.3	0.4	2.3	0.9	0.1	0.8	0.3	0.3	0.7	0.1	0.1	0.6	-0.1	0.3	0.6	0.5	-1.5	0.3	0.7	0.5	0.5
Chronic bronchitis/emphysema (father)	0.3	0.3	2.2	-0.2	0.2	0.5	0.4	0.6	0.5	-1.5	0.4	0.6	0.3	0.7	0.5	0.7	0.0	0.3	0.7	0.3	0.6
Number of incorrect matches in round	0.3	0.6	1.6	-1.1	-0.4	-0.7	-0.9	-1.0	-0.5	-0.1	-0.8	-0.7	-0.3	-0.9	-0.6	-1.3	0.7	-0.5	-0.6	-0.6	-1.0
Forced vital capacity (FVC)	0.3	1.3	5.1	1.7	0.7	1.1	1.1	1.2	0.9	1.4	0.9	0.5	1.2	1.4	0.9	0.6	-2.3	1.0	1.0	0.6	-0.9
Pain all over the body in last month	0.3	0.3	3.3	-0.6	-0.5	-0.6	-0.3	0.2	-0.3	-0.5	-0.1	-0.5	0.1	-0.3	-0.3	-0.3	1.8	-0.5	-0.4	-0.4	0.0
Medication: Simvastatin	0.3	0.4	2.3	-0.7	-0.2	-0.6	-0.7	-0.3	-0.6	-1.3	-0.7	-0.4	-0.0	-0.1	-0.6	-0.4	1.5	-0.4	-0.6	-0.1	-0.0
Illnesses of siblings	0.3	0.4	1.7	1.1	0.3	0.6	0.5	0.4	0.4	0.7	0.3	0.6	-0.1	0.9	0.4	0.9	-1.3	0.3	0.5	0.6	-0.4
Weight	0.3	1.5	3.3	-1.0	-1.8	-1.1	-1.1	-1.3	-1.0	1.3	-1.2	-1.7	-0.6	-1.0	-1.1	-1.5	0.1	-1.4	-1.2	-1.8	-0.7
Impedance of arm (right)	0.3	1.6	4.2	0.8	1.4	1.2	1.1	1.3	1.1	-0.0	1.2	1.2	1.7	1.3	1.2	1.3	0.9	1.3	1.2	1.0	2.0
Hip circumference	0.3	1.4	2.5	-1.3	-1.5	-0.9	-1.3	-1.6	-0.8	0.8	-1.5	-1.5	-0.4	-1.2	-0.9	-1.4	0.6	-1.3	-1.0	-1.6	-0.1
Worrier / anxious feelings	0.3	0.6	3.2	1.5	-0.2	-0.1	-0.2	0.2	-0.2	-0.2	0.0	0.0	-1.8	0.0	-0.3	0.1	-1.7	-0.2	-0.1	0.0	-1.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.9	5.4	0.4	-1.4	-0.5	-0.5	-0.3	-0.8	-0.1	-0.5	-0.9	-0.6	0.2	-1.0	-0.5	-2.3	-0.9	-0.8	-1.4	-1.3
Standing height	0.3	2.6	7.0	1.0	1.2	2.2	2.0	1.1	2.1	2.6	1.3	1.4	1.9	0.9	2.1	1.2	-0.0	1.6	2.2	1.1	0.8
Length of working week for main job	0.3	0.4	1.7	0.4	-0.2	-0.3	-0.7	-0.9	-0.1	0.9	-0.8	0.5	-1.3	-1.0	-0.3	0.3	0.1	-0.6	-0.2	0.5	-0.4
Medication: Amlodipine	0.3	0.4	1.3	-0.3	-0.8	-0.4	-1.1	-0.7	-0.4	-0.9	-1.0	-0.1	-0.9	-0.7	-0.5	-0.3	-0.2	-0.8	-0.3	-0.3	-0.8
Body fat percentage	0.3	1.1	2.6	-1.0	-1.3	-1.1	-1.0	-0.9	-1.0	0.7	-0.8	-1.5	-0.1	-0.5	-1.0	-1.1	1.0	-1.1	-1.2	-1.6	0.5
Exposure to tobacco smoke outside home	0.3	0.4	1.0	-1.0	-0.8	-0.2	-0.7	-0.6	-0.4	-0.3	-0.6	-0.6	-0.3	-0.3	-0.5	-0.7	-1.0	-0.8	-0.6	-0.7	-1.0
Medication for pain relief, constipation, heartburn	0.3	0.5	1.4	1.0	0.5	0.8	0.0	0.1	0.9	-1.2	0.2	0.9	-0.1	-0.0	0.9	1.0	-0.6	0.4	1.0	0.8	0.2
Whole body fat mass	0.3	1.1	2.6	-1.1	-1.4	-0.9	-0.9	-1.0	-0.8	1.0	-0.8	-1.5	0.0	-0.7	-0.9	-1.2	0.9	-1.1	-1.1	-1.6	0.2
Number of full sisters	0.3	0.4	1.1	-1.1	0.0	-1.0	-0.5	-0.8	-0.9	0.4	-0.7	-0.5	-0.2	-1.0	-0.6	-0.8	-0.2	-0.4	-0.8	0.2	0.3
Age at last live birth	0.3	0.4	2.4	-0.2	0.0	0.6	0.2	0.2	0.6	-1.2	0.3	0.2	-1.0	-0.2	0.6	0.0	-1.5	0.2	0.6	0.1	-0.2
Illnesses of siblings: Diabetes	0.3	0.4	1.4	-0.7	0.7	-0.7	0.1	0.2	-0.5	-0.8	0.5	-0.3	0.9	-0.4	-0.3	-0.3	1.0	0.3	-0.5	0.1	1.2
Smoking status: Previous	0.3	0.4	2.2	-1.2	-0.5	-0.2	-0.4	0.1	0.1	-1.0	-0.4	-0.4	-0.4	-0.7	0.0	-0.7	-1.5	-0.1	-0.0	-0.4	-1.0
Mood swings	0.3	0.6	1.2	0.4	0.4	0.8	0.8	1.1	0.8	0.8	1.1	0.4	0.8	1.1	0.7	0.7	-1.0	0.9	0.7	0.3	-0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.4	1.9	-1.4	-0.4	-0.4	-0.4	-0.8	-0.4	-0.5	-0.5	-0.3	-0.5	-1.0	-0.3	-0.8	-0.2	-0.2	-0.4	-0.6	-0.1
Hearing aid user	0.3	0.4	4.9	0.3	0.2	-0.4	-0.2	-0.0	-0.3	0.8	-0.2	0.2	0.5	0.3	-0.4	-0.1	2.2	0.1	-0.2	0.4	0.4
Medication: Lisinopril	0.3	0.4	4.4	-0.7	-0.0	-0.0	-0.6	-0.3	-0.2	-2.1	-0.5	-0.7	-0.5	-0.2	-0.1	-0.7	-0.1	-0.0	-0.3	-0.0	-0.3
Medication: Atorvastatin	0.3	0.4	1.3	0.0	-0.2	-0.8	-0.2	-0.2	-0.7	0.4	-0.2	-0.9	0.2	-0.2	-0.7	-0.8	-0.9	-0.2	-0.8	-0.5	-1.1
Illnesses of father: High blood pressure	0.3	0.4	1.4	0.8	0.8	0.4	0.2	0.0	0.2	0.6	0.3	1.0	0.4	0.3	0.4	0.5	0.5	0.2	0.4	1.1	1.2
Fractured/broken bones in last 5 years	0.3	0.3	2.6	-1.0	0.7	0.2	0.4	0.0	0.3	-0.2	0.3	0.5	0.1	-0.2	0.4	0.2	-0.1	0.3	0.5	0.6	1.6
Neuroticism (Nagel 2018)	0.2	0.5	4.7	-0.1	0.1	0.4	0.3	0.5	0.3	0.9	0.4	-0.1	-0.3	0.2	0.1	0.1	-1.5	0.4	0.3	-0.2	-2.2
Schizophrenia (2018)	0.2	0.5	1.0	1.0	0.6	0.9	0.6	0.0	1.0	0.3	0.0	0.9	-0.4	-0.2	1.0	0.9	-0.5	0.4	0.8	1.0	-0.9
Schizophrenia (2014)	0.2	0.5	1.1	0.3	0.9	1.0	0.8	0.2	1.0	0.3	0.2	1.1	0.3	0.1	1.0	0.8	-0.1	0.6	0.9	1.1	-0.5
Triglycerides	0.2	0.3	2.2	1.5	0.5	0.3	0.4	0.5	0.2	0.8	-0.2	0.5	0.7	0.6	0.3	0.2	-0.3	0.2	0.2	0.5	-0.2
Height	0.2	4.8	11.5	1.5	1.9	2.7	2.6	1.6	2.8	3.4	1.8	2.2	2.2	1.2	2.8	1.7	-0.4	2.0	2.9	2.1	1.9
Lung FVC	0.2	1.1	12.3	1.0	-0.2	-0.2	-0.3	0.7	-0.4	-1.1	0.2	-0.8	-0.7	1.0	-0.3	-0.2	-3.5	0.1	-0.3	-0.4	-1.1
Neuroticism	0.2	0.5	3.4	-0.2	0.4	0.5	0.4	0.6	0.5	-0.4	0.6	0.0	-0.9	0.3	0.5	0.1	-1.8	0.7	0.4	0.3	-1.7
Chronotype (morning person)	0.2	0.4	4.9	-0.4	0.4	-0.4	0.1	0.2	-0.2	-2.2	0.3	-0.2	-0.3	-0.3	0.0	-0.3	0.6	0.0	-0.1	0.4	0.2
Hand grip strength (left)	0.2	0.5	2.4	1.6	-0.3	-0.4	-0.2	-0.3	-0.3	1.0	-0.3	-0.8	-0.1	-0.1	-0.3	-0.9	-1.5	-0.1	-0.5	-0.2	-1.0
Frequency of depressed mood in last 2 weeks	0.2	0.3	2.2	-0.3	-0.2	-0.6	0.4	0.6	-0.3	0.7	0.6	-0.4	-0.4	0.1	-0.4	-0.3	-0.5	0.2	-0.2	-0.4	-1.5
Diabetes (mother)	0.2	0.3	1.2	1.1	0.2	-0.4	0.6	0.8	-0.3	0.1	0.9	-0.1	0.3	1.0	-0.2	0.2	-0.3	0.0	-0.3	0.2	0.9
Trunk fat percentage	0.2	0.8	2.0	-0.9	-1.1	-0.7	-0.9	-0.9	-0.6	1.1	-0.8	-1.1	0.3	-0.5	-0.7	-0.9	1.1	-0.9	-0.9	-1.4	0.9
Maternal smoking around birth	0.2	0.3	0.6	0.7	0.1	-0.7	-0.3	-0.5	-0.8	0.6	-0.1	-0.7	0.3	-0.7	-0.6	-0.5	-0.4	-0.3	-0.7	0.3	0.4
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	1.2	0.2	-0.3	-0.1	-0.3	-0.1	-0.3	0.7	-0.1	0.2	0.1	0.1	-0.4	0.1	1.1	-0.5	-0.3	0.2	0.7
Medication: Atenolol	0.2	0.2	1.7	-0.8	0.1	-0.2	-0.1	-0.4	0.1	-0.2	-0.4	0.0	-0.4	-0.7	0.0	-0.2	0.7	-0.1	0.0	0.4	-1.3
Trunk fat mass	0.2	0.9	2.1	-0.9	-1.2	-0.7	-0.8	-0.9	-0.6	1.4	-0.8	-1.2	0.3	-0.6	-0.7	-1.1	1.0	-0.9	-0.8	-1.4	0.5
Past tobacco smoking	0.2	0.4	2.0	1.2	-0.1	-0.3	-0.1	-0.4	-0.6	1.1	-0.1	-0.3	-0.1	0.3	-0.6	0.2	1.4	-0.3	-0.7	-0.3	0.5
Hair/balding pattern: Pattern 2	0.2	0.2	0.6	0.4	0.6	0.5	0.4	0.2	0.4	0.2	0.8	0.7	0.3	0.3	0.4	0.7	-0.3	0.5	0.2	0.4	0.3
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.4	1.0	-0.3	-0.2	-0.7	-0.5	-0.8	-0.7	0.3	-0.3	-0.6	-0.2	-1.0	-0.7	-0.8	0.8	-0.6	-0.9	-0.0	0.0
Forced expiratory volume in 1-second (FEV1)	0.2	0.6	5.6	0.6	-0.6	-0.1	-0.0	0.1	-0.3	0.7	-0.2	-0.6	0.2	0.4	-0.4	-0.4	-2.4	-0.3	-0.3	-0.6	-1.5
Happiness	0.2	0.3	0.7	-0.1	0.7	0.7	0.4	0.1	0.8	-0.4	0.0	0.7	0.1	-0.2	0.8	0.6	0.6	0.5	0.8	0.7	0.6
Medication: Cholesterol lowering	0.2	0.3	1.2	-1.0	0.1	-0.7	-0.5	-0.3	-0.6	-0.8	-0.3	-0.4	0.2	-0.5	-0.5	-0.7	1.1	-0.1	-0.5	0.2	-0.1
Ever highly irritable/argumentative for 2 days	0.2	0.2	0.9	0.9	0.8	0.0	0.4	0.3	0.2	0.1	0.4	0.3	0.3	0.2	0.3	0.3	-0.3	0.6	0.3	0.9	-0.2
Forced vital capacity (FVC), Best measure	0.2	0.6	3.1	1.1	-0.0	0.8	0.7	0.9	0.6	0.3	0.6	0.4	0.6	1.3	0.5	0.6	-1.7	0.5	0.7	-0.1	-0.3
Wheeze or whistling in the chest in last year	0.2	0.4	2.2	-1.0	0.0	-0.6	-0.5	-0.3	-0.2	-1.1	-0.2	-0.3	0.6	-0.9	-0.1	-0.6	1.5	-0.5	-0.2	0.4	0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.3	0.8	0.7	-0.4	-0.2	-0.5	-0.6	-0.5	-0.2	-0.6	-0.3	-0.7	-0.0	-0.6	-0.2	0.9	-0.5	-0.7	-0.4	0.3
Age at first live birth	0.2	0.3	1.8	-0.2	-0.1	0.4	0.2	0.5	0.2	-1.4	0.7	0.0	-0.8	0.5	0.2	0.3	-0.8	0.3	0.3	-0.2	0.6
Emphysema/chronic bronchitis	0.2	0.3	2.4	0.1	-0.3	0.0	-0.5	-0.4	-0.1	0.0	-0.8	-0.2	-0.4	-0.2	-0.1	-0.2	-1.6	-0.4	-0.3	-0.0	-0.8
Migraine (self-reported)	0.2	0.2	1.8	0.4	-0.3	-0.1	0.3	0.0	-0.2	1.4	0.1	-0.4	0.2	0.5	-0.3	-0.2	-0.6	0.0	-0.3	-0.8	-0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.2	1.1	0.5	0.7	-0.0	-0.0	0.0	0.2	0.1	-0.1	0.7	0.6	-0.6	0.2	0.1	-0.0	0.4	0.3	1.1	-0.6
Comparative height size at age 10	0.2	1.1	12.0	0.8	0.2	0.9	1.3	0.5	1.0	3.5	0.5	0.3	0.3	0.2	0.9	0.3	-0.4	0.8	0.9	0.0	-0.1
Ever had bowel cancer screening	0.2	0.3	1.2	-1.1	-0.7	0.2	-0.5	-0.5	0.1	-0.6	-0.8	-0.3	0.3	-0.6	0.1	-0.4	-0.3	-0.5	0.2	-0.6	-0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	0.9	0.4	0.1	0.6	0.5	0.6	0.5	0.3	0.4	0.2	0.3	0.6	0.3	0.2	0.3	0.2	0.5	0.3	-1.0
Breast cancer (self-reported)	0.2	0.2	1.5	0.1	-0.2	0.6	-0.1	-0.2	0.2	-0.5	-0.3	0.5	1.1	0.3	0.2	0.5	0.0	0.0	0.3	-0.2	1.2
Ever taken oral contraceptive pill	0.2	0.2	0.7	0.8	-0.5	-0.2	-0.3	-0.7	-0.4	0.6	-0.7	0.0	0.1	-0.9	-0.4	-0.2	-0.2	-0.6	-0.3	0.0	-0.3
Medication: Bendroflumethiazide	0.2	0.3	0.7	0.6	0.5	0.7	0.5	0.2	0.4	0.4	0.4	0.6	0.6	0.6	0.4	0.4	0.4	0.5	0.4	0.4	0.8
Ever smoked	0.2	0.3	4.5	-0.4	-0.0	0.1	0.1	0.5	0.3	-0.6	0.2	0.2	-0.2	-0.2	0.3	-0.1	-2.1	0.1	0.5	0.3	-0.3
Average weekly beer plus cider intake	0.2	0.3	0.9	-0.4	-0.1	-0.9	-0.4	-0.1	-0.7	-0.8	0.1	-0.8	-0.7	-0.3	-0.6	-0.4	0.5	-0.2	-0.5	-0.5	-0.1
Cholesterol lowering medication	0.2	0.3	2.3	0.6	-0.4	-0.1	-0.3	-0.0	-0.3	-1.1	-0.4	-0.1	0.2	0.3	-0.3	0.2	1.5	-0.6	-0.4	-0.2	-0.1
Depressed Affect (Nagel 2018)	0.1	0.3	1.1	-0.4	0.4	0.8	0.3	0.4	0.7	0.5	0.5	0.3	0.5	0.3	0.6	0.4	-1.1	0.7	0.6	-0.1	-0.6
Worry (Nagel 2018)	0.1	0.3	3.6	0.4	0.4	0.4	0.2	0.3	0.2	0.3	0.1	-0.0	-0.3	0.4	0.1	0.1	-0.8	0.5	0.2	0.3	-1.9
Reaction Time	0.1	0.3	1.6	0.1	0.3	-0.2	0.2	0.2	-0.3	-0.8	0.5	-0.6	0.9	0.3	-0.1	-0.2	1.3	0.2	-0.3	-0.1	0.8
Age at First Birth	0.1	0.1	0.8	0.5	0.4	0.1	0.4	0.4	0.2	0.5	0.9	-0.0	-0.3	0.4	0.2	0.3	0.3	0.4	0.2	0.1	0.2
Neuroticism (2016)	0.1	0.1	0.5	0.0	0.2	-0.1	0.2	-0.2	0.0	0.5	-0.3	-0.2	-0.4	-0.7	-0.0	-0.3	-0.3	0.1	0.0	0.1	-0.7
Blood Red Count	0.1	1.1	4.9	-0.3	0.9	1.1	0.0	-0.5	0.9	1.1	-0.2	1.4	1.6	0.3	0.9	0.9	1.4	0.5	0.9	0.8	2.2
Waist Hip Ratio (WHR)	0.1	0.5	4.0	-1.0	0.2	-0.1	0.1	0.8	0.0	-2.0	1.0	0.1	-0.2	0.2	0.1	0.3	-1.1	0.2	0.0	0.3	-0.1
Tanning	0.1	0.7	3.0	1.7	0.4	0.5	0.8	1.1	0.1	0.8	0.9	0.2	-0.3	1.1	0.2	0.8	-1.6	0.6	0.2	0.0	-0.8
Relative age of first facial hair	0.1	0.2	0.8	-0.3	-0.1	0.5	0.5	0.4	0.4	0.1	0.2	0.7	0.9	0.5	0.4	0.8	0.1	0.1	0.4	-0.2	0.6
Other serious medical condition/disability diagnosed by doctor	0.1	0.2	0.6	-0.7	0.1	0.1	-0.3	-0.4	0.2	0.5	-0.6	0.5	-0.2	-0.8	0.2	-0.1	0.5	-0.3	0.2	0.7	-0.4
Supplements: Zinc	0.1	0.1	0.9	0.0	0.1	-0.3	0.0	0.1	-0.2	-1.0	0.0	-0.1	0.4	0.3	-0.1	0.0	-0.2	-0.2	-0.1	0.2	0.4
Medication: Co-codamol	0.1	0.1	0.3	-0.1	-0.0	-0.2	0.0	0.5	0.0	0.0	0.2	0.3	-0.4	0.3	-0.1	0.4	-0.4	0.1	0.0	-0.0	-0.6
Leg fat-free mass (left)	0.1	0.5	1.6	-0.7	-1.3	-0.6	-0.5	-0.7	-0.4	1.0	-0.5	-1.1	-0.0	-0.6	-0.6	-1.0	-0.0	-0.7	-0.6	-1.2	-0.4
Relative age voice broke	0.1	0.1	0.5	-0.1	-0.4	0.2	0.0	0.4	-0.1	-0.4	-0.1	0.2	-0.2	0.5	-0.0	0.3	-0.7	-0.1	0.2	-0.6	-0.2
Sitting height	0.1	0.9	3.3	-0.2	0.5	1.2	1.1	0.5	1.4	1.8	0.5	0.8	0.5	0.0	1.3	0.4	-0.3	1.0	1.5	0.7	-0.9
Leg predicted mass (left)	0.1	0.5	1.5	-0.7	-1.2	-0.6	-0.4	-0.6	-0.4	1.0	-0.5	-1.1	0.1	-0.5	-0.5	-0.9	0.0	-0.7	-0.5	-1.1	-0.3
Trunk fat-free mass	0.1	0.3	2.2	-0.3	-0.6	0.2	0.2	-0.3	0.4	1.5	-0.2	-0.4	0.3	-0.4	0.2	-0.5	-0.4	-0.1	0.2	-0.4	-1.1
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.2	0.5	0.7	-0.1	-0.5	0.1	0.2	-0.5	-0.4	0.1	-0.3	-0.1	0.4	-0.4	-0.5	0.7	-0.2	-0.4	-0.0	0.7
Depression (self-reported)	0.1	0.1	0.3	0.4	-0.2	-0.1	-0.3	-0.3	-0.0	0.6	-0.3	0.0	-0.1	-0.1	-0.1	-0.0	-0.4	-0.3	-0.1	-0.0	-0.5
Trunk predicted mass	0.1	0.3	2.3	-0.3	-0.6	0.2	0.2	-0.3	0.3	1.5	-0.2	-0.4	0.3	-0.4	0.2	-0.5	-0.4	-0.1	0.2	-0.4	-1.2
High blood pressure (siblings)	0.1	0.1	0.4	-0.6	-0.1	-0.3	-0.5	-0.5	-0.2	0.2	-0.4	-0.1	0.3	-0.5	-0.2	-0.4	0.5	0.1	-0.2	-0.4	0.6
Arm fat-free mass (right)	0.1	0.3	1.8	-0.4	-0.7	-0.1	-0.0	-0.5	0.1	1.3	-0.4	-0.5	0.1	-0.5	0.0	-0.5	0.2	-0.3	0.0	-0.5	-0.8
Number of full brothers	0.1	0.1	0.8	-0.3	0.0	-0.2	-0.1	0.2	-0.1	0.4	0.1	-0.0	0.7	0.2	-0.1	-0.2	0.9	-0.1	-0.2	0.1	0.5
Whole body fat-free mass	0.1	0.4	1.8	-0.5	-0.9	-0.1	-0.2	-0.5	0.0	1.4	-0.4	-0.8	0.1	-0.6	-0.2	-0.8	-0.2	-0.4	-0.1	-0.8	-0.9
Leg fat-free mass (right)	0.1	0.4	1.3	-0.6	-1.1	-0.5	-0.4	-0.5	-0.3	1.1	-0.4	-0.9	0.0	-0.5	-0.4	-0.8	0.1	-0.6	-0.4	-1.0	-0.3
Mineral and other dietary supplements	0.1	0.2	0.9	-0.4	0.5	0.3	0.0	0.1	0.4	0.0	-0.1	0.8	0.2	-0.2	0.4	0.4	1.0	0.2	0.3	0.7	0.6
Whole body water mass	0.1	0.4	1.4	-0.5	-1.0	-0.2	-0.2	-0.5	-0.0	1.2	-0.5	-0.8	0.1	-0.6	-0.2	-0.8	-0.2	-0.5	-0.2	-0.8	-0.9
Leg predicted mass (right)	0.1	0.3	1.3	-0.5	-1.0	-0.4	-0.2	-0.4	-0.2	1.1	-0.3	-0.8	0.2	-0.4	-0.3	-0.7	0.2	-0.5	-0.3	-0.8	-0.3
Supplements: Fish oil (including cod liver oil)	0.1	0.1	0.7	0.9	-0.2	0.4	0.1	0.1	0.2	-0.4	0.3	-0.3	0.4	0.4	0.2	-0.0	-0.5	0.3	0.2	-0.3	-0.3
High cholesterol (Self-reported)	0.1	0.3	1.4	0.4	0.6	0.3	0.2	0.2	0.1	-1.0	0.2	0.6	0.5	0.2	0.2	0.4	1.2	0.1	-0.0	0.8	0.4
Basal metabolic rate	0.1	0.5	2.0	-0.6	-1.1	-0.3	-0.3	-0.6	-0.2	1.4	-0.5	-0.9	0.1	-0.6	-0.3	-0.9	-0.0	-0.6	-0.3	-1.0	-0.8
Arm fat-free mass (left)	0.1	0.6	2.0	-0.4	-1.1	-0.4	-0.3	-0.7	-0.2	1.4	-0.6	-1.0	-0.1	-0.7	-0.3	-1.0	-0.3	-0.7	-0.4	-0.9	-1.3
Diastolic blood pressure, automated reading	0.1	0.4	0.9	0.7	-0.2	-0.3	-0.9	-0.9	-0.3	-0.8	-0.8	0.3	0.7	-0.6	-0.1	0.2	0.7	-0.9	-0.4	0.4	0.9
Ever depressed for a whole week	0.1	0.1	0.4	0.2	-0.1	-0.3	-0.3	-0.3	-0.2	0.3	-0.3	0.1	-0.6	-0.1	-0.3	0.2	0.5	-0.2	-0.2	-0.0	-0.2
Arm predicted mass (left)	0.1	0.6	2.0	-0.6	-1.1	-0.5	-0.4	-0.8	-0.3	1.4	-0.8	-1.0	-0.1	-0.8	-0.4	-1.1	-0.1	-0.7	-0.4	-0.9	-1.2
Hair/balding pattern: Pattern 4	0.0	0.1	0.4	0.2	0.3	0.1	-0.0	-0.2	0.1	-0.5	-0.0	-0.2	-0.3	-0.5	0.3	-0.1	-0.3	0.1	0.2	0.1	0.6
Arm predicted mass (right)	0.0	0.2	2.3	-0.5	-0.5	0.2	0.2	-0.3	0.4	1.5	-0.1	-0.3	0.3	-0.4	0.3	-0.3	0.0	-0.1	0.3	-0.3	-0.6

Hub : Genes

ADD3

Models

Trait associations