TWAS
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Models
Genes
Traits
[Hub]/) :
Traits
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Bipolar Disorder or Schizophrenia
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chr2:224,636,490-226,142,508
Best TWAS P=1.55e-07 · Best GWAS P=2.21e-06 conditioned to 0.211
224.6M
224.8M
225M
225.2M
225.4M
225.6M
225.8M
226M
226.2M
0
1
2
3
4
5
6
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
ROSMAP
Brain Pre-frontal Cortex
CUL3
0.04
0.01
blup
498
0.01
0.0076
-4.7
-5.2
1.5e-07
0.74
0
0.96
TRUE