Best TWAS P=2.34e-10 · Best GWAS P=1.77e-11 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Colon Adenocarcinoma | NGEF | 0.14 | 0.03 | lasso | 4 | 0.03 | 6.2e-03 | 6.7 | 6.3 | 2.3e-10 | 0.98 | 0.00 | 0.94 | TRUE |
| 2 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | EFHD1 | 0.11 | 0.01 | blup | 70 | 0.03 | 1.0e-02 | 6.2 | 5.5 | 4.8e-08 | 0.37 | 0.01 | 0.88 | TRUE |
| 3 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | NGEF | 0.28 | 0.11 | enet | 11 | 0.18 | 1.1e-05 | 6.7 | 5.5 | 4.1e-08 | 0.85 | 0.00 | 0.96 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | KCNJ13 | 0.03 | 0.00 | blup | 35 | 0.01 | 4.3e-02 | 6.1 | -5.3 | 1.1e-07 | -0.43 | 0.01 | 0.66 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | NGEF | 0.04 | 0.03 | enet | 7 | 0.03 | 5.6e-04 | 6.0 | -5.5 | 2.8e-08 | -0.42 | 0.15 | 0.73 | FALSE |