Best TWAS P=1.21e-07 · Best GWAS P=1.8e-07 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | METTL21A | 0.18 | 0.20 | lasso | 7 | 0.21 | 2.0e-25 | 5.1 | -5.2 | 2.0e-07 | -0.97 | 0.03 | 0.97 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | METTL21A | 0.10 | 0.11 | enet | 10 | 0.12 | 3.7e-15 | 5.2 | -5.3 | 1.2e-07 | -0.96 | 0.02 | 0.98 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | CREB1 | 0.08 | 0.02 | lasso | 3 | 0.03 | 9.1e-05 | 5.0 | 5.3 | 1.3e-07 | 0.88 | 0.04 | 0.95 | FALSE |