TWAS
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Models
Genes
Traits
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Traits
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Bipolar Disorder or Schizophrenia
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chr1:154,219,485-155,625,602
Best TWAS P=2.1e-07 · Best GWAS P=4.42e-07 conditioned to 0.342
154.2M
154.4M
154.6M
154.8M
155M
155.2M
155.4M
155.6M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
YFS
Blood
PBXIP1
0.04
0.03
enet
13
0.03
6.2e-10
4.7
-5.2
2.1e-07
-0.89
0.03
0.96
TRUE
1
GTEx
Adipose Subcutaneous
PBXIP1
0.06
0.04
lasso
5
0.02
5.8e-03
5.0
-5.1
3.0e-07
-0.96
0.02
0.97
FALSE