Best TWAS P=1.09e-10 · Best GWAS P=7.04e-09 conditioned to 0.00217
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | CEP170 | 0.05 | 0.02 | bslmm | 378 | 0.03 | 1.9e-04 | -3.2 | 6.5 | 1.1e-10 | -0.48 | 0.23 | 0.39 | TRUE |
| 2 | GTEx | Cells EBV-transformed lymphocytes | SDCCAG8 | 0.36 | 0.24 | lasso | 8 | 0.34 | 5.7e-12 | -5.2 | -5.1 | 2.7e-07 | 0.14 | 0.60 | 0.39 | FALSE |
| 3 | NTR | Blood | SDCCAG8 | 0.03 | 0.01 | blup | 356 | 0.01 | 1.4e-04 | -2.4 | -5.7 | 1.2e-08 | 0.15 | 0.95 | 0.01 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | AKT3 | 0.02 | 0.00 | blup | 155 | 0.00 | 3.2e-01 | -5.0 | -5.8 | 5.2e-09 | 0.87 | 0.04 | 0.70 | FALSE |