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chr1:149,672,809-151,435,941

Best TWAS P=3.5e-11 · Best GWAS P=1.02e-11 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
11	The Cancer Genome Atlas	Testicular Germ Cell Tumors	PLEKHO1	0.05	0.08	lasso	1	0.05	6.6e-03	-6.6	-6.6	3.5e-11	0.96	0.00	0.64	TRUE
10	The Cancer Genome Atlas	Prostate Adenocarcinoma	RPRD2	0.05	0.02	enet	5	0.02	1.6e-03	-5.5	-6.1	1.3e-09	0.66	0.00	0.88	FALSE
1	GTEx	Cells Transformed fibroblasts	HIST2H2BF	0.07	0.05	lasso	5	0.05	8.9e-05	-5.6	-6.0	2.7e-09	0.86	0.12	0.82	FALSE
4	GTEx	Esophagus Muscularis	PLEKHO1	0.06	0.05	lasso	4	0.02	1.4e-02	-6.0	5.8	7.1e-09	-0.83	0.05	0.48	FALSE
6	GTEx	Esophagus Muscularis	RP11-196G18.22	0.18	0.02	enet	9	0.01	1.2e-01	-5.8	5.7	1.5e-08	-0.73	0.05	0.12	FALSE
9	YFS	Blood	RPRD2	0.14	0.20	lasso	8	0.20	1.2e-63	-5.5	-5.6	1.7e-08	0.65	0.98	0.02	FALSE
8	NTR	Blood	ANP32E	0.01	0.01	enet	6	0.00	1.3e-02	-6.7	-5.6	2.2e-08	0.89	0.02	0.95	FALSE
2	GTEx	Colon Transverse	CTSS	0.10	0.15	lasso	4	0.16	2.7e-08	-5.1	5.3	9.4e-08	-0.43	0.09	0.87	FALSE
5	GTEx	Esophagus Muscularis	RPRD2	0.09	0.07	lasso	4	0.06	1.8e-04	-5.0	-5.3	1.2e-07	0.69	0.52	0.13	FALSE
3	GTEx	Esophagus Mucosa	MRPS21	0.09	0.06	lasso	2	0.05	3.0e-04	-5.4	-5.2	1.8e-07	0.61	0.35	0.16	FALSE
7	GTEx	Testis	RPRD2	0.33	0.13	lasso	7	0.19	9.1e-09	2.8	-5.2	2.0e-07	0.59	0.68	0.28	FALSE