[Hub]/) : Traits : Bipolar Disorder or Schizophrenia :

chr1:149,672,809-151,435,941

Best TWAS P=3.5e-11 · Best GWAS P=1.02e-11 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells Transformed fibroblasts HIST2H2BF 0.07 0.05 lasso 5 0.05 8.9e-05 -5.6 -6.0 2.7e-09 0.86 0.12 0.82 FALSE
2 GTEx Colon Transverse CTSS 0.10 0.15 lasso 4 0.16 2.7e-08 -5.1 5.3 9.4e-08 -0.43 0.09 0.87 FALSE
3 GTEx Esophagus Mucosa MRPS21 0.09 0.06 lasso 2 0.05 3.0e-04 -5.4 -5.2 1.8e-07 0.61 0.35 0.16 FALSE
4 GTEx Esophagus Muscularis PLEKHO1 0.06 0.05 lasso 4 0.02 1.4e-02 -6.0 5.8 7.1e-09 -0.83 0.05 0.48 FALSE
5 GTEx Esophagus Muscularis RPRD2 0.09 0.07 lasso 4 0.06 1.8e-04 -5.0 -5.3 1.2e-07 0.69 0.52 0.13 FALSE
6 GTEx Esophagus Muscularis RP11-196G18.22 0.18 0.02 enet 9 0.01 1.2e-01 -5.8 5.7 1.5e-08 -0.73 0.05 0.12 FALSE
7 GTEx Testis RPRD2 0.33 0.13 lasso 7 0.19 9.1e-09 2.8 -5.2 2.0e-07 0.59 0.68 0.28 FALSE
8 NTR Blood ANP32E 0.01 0.01 enet 6 0.00 1.3e-02 -6.7 -5.6 2.2e-08 0.89 0.02 0.95 FALSE
9 YFS Blood RPRD2 0.14 0.20 lasso 8 0.20 1.2e-63 -5.5 -5.6 1.7e-08 0.65 0.98 0.02 FALSE
10 The Cancer Genome Atlas Prostate Adenocarcinoma RPRD2 0.05 0.02 enet 5 0.02 1.6e-03 -5.5 -6.1 1.3e-09 0.66 0.00 0.88 FALSE
11 The Cancer Genome Atlas Testicular Germ Cell Tumors PLEKHO1 0.05 0.08 lasso 1 0.05 6.6e-03 -6.6 -6.6 3.5e-11 0.96 0.00 0.64 TRUE