Best TWAS P=3.11e-08 · Best GWAS P=1.36e-06 conditioned to 0.019
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | CPNE7 | 0.09 | 0.02 | bslmm | 452 | 0.04 | 1.4e-05 | 4.2 | -5.4 | 7.1e-08 | -0.55 | 0.16 | 0.75 | FALSE |
| 2 | GTEx | Adrenal Gland | SPATA33 | 0.21 | 0.12 | enet | 15 | 0.18 | 6.9e-07 | -3.5 | 5.4 | 5.3e-08 | 0.71 | 0.09 | 0.83 | FALSE |
| 3 | GTEx | Colon Sigmoid | SPG7 | 0.13 | -0.01 | lasso | 5 | -0.01 | 7.2e-01 | 4.5 | -5.4 | 8.0e-08 | -0.83 | 0.04 | 0.33 | FALSE |
| 4 | GTEx | Pancreas | CDK10 | 0.18 | -0.01 | lasso | 5 | 0.02 | 5.1e-02 | -3.5 | 5.2 | 2.4e-07 | 0.46 | 0.06 | 0.20 | FALSE |
| 5 | GTEx | Skin Sun Exposed Lower leg | SPATA33 | 0.10 | 0.01 | enet | 25 | 0.05 | 6.3e-05 | -4.6 | 5.5 | 3.1e-08 | 0.51 | 0.07 | 0.83 | TRUE |
| 6 | The Cancer Genome Atlas | Prostate Adenocarcinoma | SPG7 | 0.07 | 0.03 | enet | 11 | 0.04 | 3.7e-05 | -4.7 | -5.1 | 3.1e-07 | -0.32 | 0.01 | 0.91 | FALSE |