Best TWAS P=1.1e-07 · Best GWAS P=5.45e-07 conditioned to 0.254
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells EBV-transformed lymphocytes | TMEM110 | 0.13 | 0.00 | enet | 11 | 0.04 | 1.6e-02 | -4.7 | -5.1 | 2.8e-07 | 0.64 | 0.10 | 0.52 | FALSE |
| 2 | GTEx | Muscle Skeletal | ITIH4-AS1 | 0.06 | 0.03 | lasso | 4 | 0.06 | 2.3e-06 | -4.4 | -5.3 | 1.1e-07 | 0.82 | 0.15 | 0.84 | TRUE |
| 3 | The Cancer Genome Atlas | Rectum Adenocarcinoma | ITIH4 | 0.12 | 0.09 | blup | 53 | 0.06 | 1.4e-02 | -4.9 | -5.2 | 2.4e-07 | 0.94 | 0.02 | 0.68 | FALSE |