TWAS hub - ITIH4-AS1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.0340	0.0210	7.2e-03	0.062	NA	0.034	NA	0.035	8.8e-06	NA	8.4e-04	NA	6.7e-04
2	GTEx	Artery Aorta	0.3760	0.0650	0.0e+00	0.452	NA	0.395	NA	0.415	2.4e-27	NA	4.0e-23	NA	1.4e-24
3	GTEx	Artery Coronary	0.1090	0.0450	5.9e-05	0.125	NA	0.158	NA	0.122	5.5e-05	NA	5.5e-06	NA	6.7e-05
4	GTEx	Artery Tibial	0.6807	0.0669	0.0e+00	0.493	NA	0.502	NA	0.519	1.1e-43	NA	7.3e-45	NA	5.5e-47
5	GTEx	Brain Cerebellum	0.2470	0.0810	4.7e-05	0.005	NA	0.028	NA	0.048	2.3e-01	NA	5.1e-02	NA	1.5e-02
6	GTEx	Brain Cortex	0.2030	0.0910	3.5e-03	0.014	NA	0.082	NA	0.044	1.3e-01	NA	2.8e-03	NA	2.3e-02
7	GTEx	Brain Putamen basal ganglia	0.1840	0.0800	2.1e-03	0.005	NA	0.057	NA	0.021	2.4e-01	NA	1.8e-02	NA	1.0e-01
8	GTEx	Cells EBV-transformed lymphocytes	0.1140	0.0590	2.1e-03	0.052	NA	0.025	NA	0.001	8.5e-03	NA	5.2e-02	NA	3.0e-01
9	GTEx	Colon Sigmoid	0.2520	0.1040	1.1e-04	0.185	NA	0.134	NA	0.188	4.0e-07	NA	1.9e-05	NA	3.2e-07
10	GTEx	Colon Transverse	0.1980	0.1020	2.9e-03	0.030	NA	0.048	NA	0.048	1.4e-02	NA	2.5e-03	NA	2.4e-03
11	GTEx	Esophagus Mucosa	0.0600	0.0310	6.8e-04	0.033	NA	0.046	NA	0.052	2.6e-03	NA	4.8e-04	NA	2.2e-04
12	GTEx	Esophagus Muscularis	0.0720	0.0370	1.4e-03	0.052	NA	0.068	NA	0.070	4.3e-04	NA	6.1e-05	NA	4.7e-05
13	GTEx	Lung	0.3160	0.0685	1.7e-16	0.262	NA	0.242	NA	0.258	3.7e-20	NA	1.6e-18	NA	8.0e-20
14	GTEx	Muscle Skeletal	0.0647	0.0293	2.0e-06	0.029	NA	0.057	NA	0.058	7.2e-04	NA	2.5e-06	NA	2.3e-06
15	GTEx	Nerve Tibial	0.1896	0.0493	3.6e-12	0.223	NA	0.204	NA	0.206	8.5e-16	NA	1.9e-14	NA	1.5e-14
16	GTEx	Pancreas	0.1740	0.0800	3.4e-04	0.054	NA	0.069	NA	0.049	2.6e-03	NA	7.5e-04	NA	4.0e-03
17	GTEx	Pituitary	0.3800	0.1270	2.3e-04	0.310	NA	0.330	NA	0.289	1.5e-08	NA	4.5e-09	NA	5.7e-08
18	GTEx	Skin Not Sun Exposed Suprapubic	0.1230	0.0680	4.5e-03	0.039	NA	0.066	NA	0.053	3.4e-03	NA	1.6e-04	NA	7.0e-04
19	GTEx	Skin Sun Exposed Lower leg	0.1490	0.0600	2.2e-07	0.106	NA	0.109	NA	0.106	4.2e-09	NA	2.4e-09	NA	4.7e-09
20	GTEx	Spleen	0.3330	0.1030	3.4e-05	0.351	NA	0.300	NA	0.338	7.2e-10	NA	2.0e-08	NA	1.7e-09
21	GTEx	Testis	0.2350	0.0630	2.5e-07	0.133	NA	0.213	NA	0.201	1.7e-06	NA	8.2e-10	NA	2.7e-09
22	GTEx	Thyroid	0.3070	0.0640	0.0e+00	0.238	NA	0.244	NA	0.267	3.4e-18	NA	1.2e-18	NA	1.6e-20
23	GTEx	Whole Blood	0.3290	0.0670	0.0e+00	0.244	NA	0.222	NA	0.248	2.6e-22	NA	2.9e-20	NA	9.7e-23

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23
Worry (Nagel 2018)	17.7	37.4	57.2	-6.5	-6.7	-6.7	-6.8	-5.6	-2.9	-7.6	-6.5	-6.0	-6.6	-6.0	-4.5	-6.5	-7.3	-6.5	4.0	-6.1	-5.7	-6.3	-6.5	-3.5	-6.2	-7.1
Worrier / anxious feelings	17.3	32.7	54.9	-6.2	-6.1	-5.6	-6.3	-5.4	-2.5	-7.4	-6.2	-5.4	-6.1	-5.7	-4.5	-6.2	-6.1	-6.5	5.2	-5.7	-5.9	-6.0	-6.2	-2.5	-5.1	-6.2
Bipolar Disorder (2011)	15.5	15.0	28.2	-4.2	-4.1	-4.7	-3.8	-3.6	-1.4	-3.8	-4.8	-3.6	-4.4	-3.6	-2.6	-4.0	-5.3	-3.9	4.0	-3.8	-4.5	-3.1	-4.4	-1.5	-3.2	-4.0
Bipolar Disorder or Schizophrenia	11.8	28.8	61.4	-5.9	-5.9	-5.0	-5.5	-4.9	-2.1	-5.9	-7.8	-4.9	-6.4	-5.8	-3.3	-6.1	-7.1	-5.8	5.9	-4.8	-5.3	-3.6	-5.6	-0.2	-4.3	-5.9
Nervous feelings	10.0	18.6	28.1	-4.8	-4.9	-4.5	-4.7	-3.8	-2.3	-5.0	-5.3	-4.1	-4.9	-4.2	-2.9	-4.7	-5.3	-4.7	3.2	-4.0	-3.5	-3.9	-4.8	-2.1	-4.3	-5.2
Number of incorrect matches in round	9.8	16.3	22.6	-3.1	-4.6	-4.2	-4.5	-4.2	-2.9	-3.6	-2.4	-4.7	-3.1	-3.5	-4.4	-4.5	-4.2	-4.7	4.2	-4.6	-4.8	-4.4	-4.0	-2.4	-4.2	-4.6
Schizophrenia (2014)	9.4	20.7	43.6	-5.1	-5.1	-4.0	-4.7	-4.2	-2.7	-4.8	-6.6	-4.4	-5.4	-4.6	-2.8	-5.5	-5.5	-4.9	4.8	-4.3	-4.1	-2.8	-4.3	-0.4	-4.1	-5.5
Schizophrenia (2018)	8.6	17.9	32.7	-4.2	-4.9	-4.0	-4.6	-3.9	-2.3	-4.6	-5.7	-4.3	-4.7	-4.4	-3.1	-5.0	-4.9	-4.7	3.7	-4.3	-4.0	-2.6	-4.2	-0.8	-4.1	-5.1
BMI	8.1	46.7	83.4	7.0	8.0	6.3	7.5	5.8	2.8	8.8	9.1	6.8	6.6	6.6	5.0	7.8	8.4	8.0	-7.8	6.4	6.2	5.7	7.5	1.1	5.2	7.2
Neuroticism (Nagel 2018)	7.7	18.0	25.8	-4.7	-4.5	-4.7	-4.7	-4.4	-2.5	-4.5	-3.6	-4.3	-5.1	-4.1	-3.5	-4.2	-4.9	-4.1	2.1	-4.1	-4.2	-4.5	-4.3	-3.6	-4.8	-4.8
Headache pain in last month	7.6	13.1	24.4	-4.9	-3.8	-3.8	-3.5	-2.8	-3.1	-4.6	-3.8	-3.4	-4.9	-4.5	-2.2	-3.7	-4.2	-3.2	2.7	-3.0	-2.2	-4.0	-4.1	-2.0	-3.0	-3.5
Smoking Status	7.5	18.1	28.8	3.7	5.0	5.4	4.9	3.9	2.8	4.7	3.5	4.5	3.5	4.2	4.4	4.6	4.7	5.0	-3.4	4.3	4.5	3.8	4.8	2.6	3.8	4.3
Tense / ‘highly strung’	7.5	12.5	17.7	-3.6	-4.0	-3.9	-4.0	-2.9	-2.3	-3.6	-3.2	-3.6	-4.2	-3.3	-2.8	-3.6	-4.0	-3.8	2.6	-3.6	-3.5	-3.5	-4.0	-2.6	-3.6	-4.0
Verbal and Numeric Reasoning (VNR)	7.4	17.8	29.6	3.3	4.9	4.7	4.6	3.5	2.2	4.8	4.9	4.3	3.0	4.9	3.1	4.9	5.4	4.7	-2.2	4.2	3.7	4.9	4.2	1.6	4.6	5.4
Major Depression (MDD)	7.3	8.8	12.7	-2.6	-3.2	-3.4	-3.4	-3.6	-1.3	-2.7	-3.5	-3.0	-2.8	-2.4	-2.5	-3.1	-3.6	-3.1	1.6	-3.2	-3.4	-3.2	-2.8	-2.2	-3.2	-3.4
Neuroticism	7.2	17.3	24.7	-4.5	-4.4	-5.0	-4.5	-4.4	-2.2	-3.9	-3.7	-4.2	-4.9	-3.9	-3.7	-4.2	-4.7	-4.2	2.2	-4.4	-4.6	-3.9	-4.0	-3.4	-4.7	-4.7
Depression (self-reported)	7.2	8.7	13.9	-2.7	-3.3	-2.8	-3.4	-3.3	-1.3	-2.6	-2.7	-3.2	-2.8	-3.3	-2.7	-3.5	-2.4	-3.3	1.7	-3.3	-2.7	-3.1	-3.3	-2.0	-3.2	-3.7
Bipolar Disorder (2018)	7.0	11.1	28.0	-4.2	-3.3	-2.7	-3.0	-2.7	-0.5	-3.8	-5.3	-2.5	-4.3	-3.8	-1.4	-3.5	-5.1	-3.3	4.6	-2.2	-3.5	-2.5	-3.7	0.8	-1.8	-3.0
Frequency of tenseness / restlessness in last 2 weeks	7.0	10.9	16.0	-2.9	-3.4	-4.0	-3.6	-3.8	-1.4	-3.0	-3.2	-3.4	-3.3	-3.5	-3.2	-3.3	-3.5	-3.4	1.2	-3.7	-3.2	-3.4	-3.3	-2.9	-3.7	-3.9
Height	6.9	133.1	201.6	-11.6	-12.3	-13.9	-12.5	-10.7	-9.8	-11.6	-6.6	-12.4	-12.4	-10.4	-13.4	-9.9	-11.0	-12.2	6.5	-12.1	-12.3	-14.2	-12.9	-13.4	-10.4	-8.8
Intelligence (Savage-Jansen 2018)	6.7	20.6	34.3	3.6	5.3	5.1	5.0	3.6	2.5	5.2	4.8	4.5	3.3	4.9	4.0	4.9	5.9	5.3	-1.4	4.2	3.9	5.8	4.9	2.6	5.1	5.5
Past tobacco smoking	6.6	12.1	21.3	-2.4	-3.9	-4.6	-4.0	-3.1	-1.9	-4.3	-2.9	-3.6	-2.3	-3.3	-3.4	-3.7	-4.0	-4.0	2.7	-3.9	-4.0	-3.7	-3.8	-1.9	-3.2	-3.7
Suffer from ‘nerves’	6.5	10.3	16.8	-3.3	-3.5	-4.0	-3.8	-3.2	-2.3	-2.9	-1.9	-3.5	-3.7	-2.2	-2.9	-3.5	-3.4	-3.2	1.2	-3.4	-3.1	-3.2	-2.7	-2.8	-4.1	-4.1
Ulcerative Colitis	6.3	9.1	16.2	-2.7	-3.1	-3.3	-3.4	-3.3	-3.1	-2.0	-2.0	-3.2	-2.9	-2.5	-3.2	-3.1	-2.6	-3.2	-0.3	-3.7	-2.9	-3.1	-2.6	-3.5	-4.0	-3.8
Sitting height	6.3	44.7	72.8	-6.2	-7.3	-8.0	-7.6	-6.3	-5.0	-5.2	-2.7	-7.5	-6.8	-5.6	-8.0	-6.2	-6.0	-7.3	1.8	-7.6	-7.8	-7.8	-7.7	-8.5	-6.8	-5.6
Townsend deprivation index at recruitment	6.2	8.8	15.4	1.2	3.5	2.6	3.4	3.1	1.0	3.7	1.8	3.5	0.9	2.4	3.4	3.3	2.7	3.9	-3.2	3.4	3.2	3.3	3.7	1.9	2.9	3.0
Fluid intelligence score	5.9	12.3	21.2	2.6	4.0	3.9	4.1	3.3	2.3	3.5	3.4	3.7	2.2	3.7	3.1	4.0	3.9	3.9	-1.2	3.7	3.1	4.5	3.2	1.8	4.3	4.6
Standing height	5.9	58.9	91.2	-7.6	-8.3	-9.6	-8.2	-6.8	-5.3	-8.8	-4.8	-8.1	-8.4	-7.2	-8.6	-6.8	-7.7	-8.3	4.7	-7.9	-8.3	-8.9	-9.1	-8.3	-6.4	-5.7
Neuroticism (2016)	5.7	8.2	12.8	-2.8	-3.2	-3.6	-3.4	-3.1	-1.4	-2.6	-2.2	-3.2	-3.0	-2.5	-2.7	-2.8	-3.2	-3.2	1.5	-3.3	-3.5	-2.5	-2.8	-2.2	-3.0	-2.9
Body mass index (BMI)	5.5	23.6	44.4	5.0	5.7	4.8	5.1	4.0	1.7	6.7	6.1	4.9	5.0	4.7	3.7	5.2	5.7	5.6	-5.7	4.4	4.4	4.6	5.6	1.2	3.5	4.8
Ever smoked	5.5	9.6	16.7	2.3	3.3	4.1	3.4	2.6	1.6	3.9	2.8	2.9	2.2	2.8	3.0	3.0	4.0	3.5	-1.9	3.2	3.5	3.9	3.5	2.1	3.0	3.2
Seen doctor (GP) for nerves, anxiety, tension or depression	5.4	8.3	14.3	-2.9	-3.3	-2.7	-3.5	-2.8	-1.0	-3.6	-2.9	-3.1	-3.2	-2.7	-2.1	-3.3	-3.3	-3.2	1.8	-2.9	-2.2	-2.7	-3.0	-1.6	-3.2	-3.8
Diabetes diagnosed by doctor	5.4	8.9	12.4	3.4	3.5	2.8	3.5	2.6	2.2	2.6	2.0	3.4	3.2	2.1	3.0	3.4	3.3	3.4	-2.8	3.0	3.3	2.9	3.1	2.2	3.0	3.1
Impedance of whole body	5.3	26.8	69.6	-6.1	-5.5	-5.2	-4.8	-2.9	-1.7	-7.9	-8.3	-3.9	-5.4	-5.7	-1.9	-5.2	-7.9	-5.3	6.7	-3.5	-3.6	-4.7	-5.9	0.5	-3.0	-4.9
Smoking status: Previous	5.2	7.7	12.0	1.8	3.2	3.5	3.2	2.6	1.6	3.3	2.3	2.9	1.7	2.8	2.8	3.0	2.9	3.3	-2.1	3.1	3.5	2.7	3.1	1.5	2.6	2.9
LDL Cholesterol	5.1	8.1	11.9	2.6	3.2	3.5	3.0	3.3	2.9	2.3	1.6	3.3	2.9	2.7	3.1	2.8	2.6	3.0	-2.2	3.1	2.9	2.4	2.7	2.7	3.2	2.9
Blood Eosinophil Count	5.1	39.1	82.6	5.8	6.9	7.0	6.7	5.0	4.1	5.3	5.6	6.3	5.5	7.3	4.7	6.6	7.2	6.9	-9.1	7.1	7.4	5.5	7.6	1.4	4.4	6.1
Type 2 Diabetes (T2D) (2018)	5.1	9.6	15.2	3.1	3.7	3.0	3.9	3.1	1.9	2.2	1.5	3.7	2.9	2.0	3.5	3.7	3.1	3.7	-2.6	3.6	3.7	2.5	3.3	2.5	3.1	3.4
Happiness	5.1	6.2	8.5	-2.4	-2.6	-2.9	-2.6	-2.7	-1.6	-2.1	-2.0	-2.6	-2.8	-2.3	-2.8	-2.2	-2.6	-2.8	2.0	-2.5	-2.7	-2.6	-2.8	-2.4	-2.4	-2.3
Impedance of arm (right)	5.0	23.3	52.6	-5.3	-5.3	-5.0	-4.7	-3.1	-1.8	-7.2	-7.2	-4.0	-4.6	-5.1	-2.6	-4.8	-7.0	-5.1	6.1	-3.5	-3.6	-4.8	-5.6	-0.3	-3.0	-4.4
Ever highly irritable/argumentative for 2 days	5.0	6.1	9.1	2.2	3.0	2.3	2.9	2.0	2.2	2.1	2.5	2.7	1.8	2.3	2.1	2.8	3.0	2.9	-2.4	2.4	2.3	2.6	2.9	1.0	2.5	2.9
Diabetes (self-reported)	4.9	7.6	11.6	3.1	3.3	2.8	3.3	2.3	1.2	2.3	2.1	3.1	2.9	2.0	2.6	3.2	3.2	3.1	-2.9	2.9	3.4	2.5	3.1	1.7	2.5	2.7
Impedance of arm (left)	4.9	22.6	51.3	-5.3	-5.2	-5.2	-4.6	-3.0	-1.8	-6.8	-7.2	-3.9	-4.7	-5.1	-2.5	-4.8	-7.1	-5.0	5.7	-3.5	-3.8	-4.5	-5.5	-0.3	-3.1	-4.5
Hand grip strength (left)	4.8	12.7	22.7	-3.6	-4.1	-3.6	-3.9	-2.3	-2.7	-4.5	-2.3	-3.6	-3.3	-4.0	-3.1	-3.9	-3.3	-4.2	4.3	-3.5	-3.3	-4.8	-4.5	-1.0	-2.4	-3.1
Guilty feelings	4.8	7.2	13.7	-2.3	-2.8	-3.1	-2.9	-3.7	-0.0	-1.9	-3.5	-2.9	-2.5	-2.1	-2.4	-2.9	-3.1	-2.6	2.0	-3.1	-3.2	-2.1	-2.0	-1.8	-2.9	-3.2
Depression (Nagel 2018)	4.7	7.0	15.0	-2.0	-3.0	-3.0	-2.8	-2.3	-0.8	-3.9	-2.2	-2.8	-2.4	-2.8	-2.3	-2.9	-3.4	-2.9	1.6	-2.7	-2.7	-2.4	-2.8	-1.7	-2.5	-3.1
Forced expiratory volume in 1-second (FEV1), predicted	4.7	9.7	14.4	-3.1	-3.4	-3.8	-3.4	-2.7	-2.8	-3.3	-2.3	-3.1	-3.1	-3.4	-3.0	-2.8	-3.7	-3.2	1.6	-2.9	-3.5	-3.3	-3.7	-3.2	-2.9	-2.5
Prospective memory result	4.6	5.6	9.4	-2.3	-2.7	-3.0	-2.7	-2.2	-0.7	-2.5	-2.6	-2.5	-2.2	-1.9	-2.1	-2.5	-3.1	-2.6	1.8	-2.2	-2.6	-2.6	-2.1	-1.5	-2.4	-2.5
Friendships satisfaction	4.6	5.7	9.1	-3.0	-2.6	-2.7	-2.8	-1.9	-1.8	-2.5	-1.7	-2.5	-3.0	-1.9	-2.0	-2.2	-2.3	-2.6	2.0	-2.3	-2.4	-3.0	-2.4	-1.8	-2.3	-2.4
Frequency of depressed mood in last 2 weeks	4.4	6.1	9.8	-2.4	-2.6	-2.7	-2.5	-2.4	-1.2	-2.9	-1.8	-2.5	-3.1	-2.5	-2.3	-2.5	-2.9	-2.5	0.4	-2.5	-2.5	-2.1	-2.6	-2.4	-2.8	-3.0
Forced vital capacity (FVC), Best measure	4.4	16.2	22.1	-3.7	-4.6	-4.6	-4.6	-3.6	-3.1	-4.3	-2.4	-4.6	-3.7	-4.5	-4.0	-4.2	-3.8	-4.4	1.8	-4.5	-4.4	-3.8	-4.7	-3.9	-3.9	-4.0
Seen a psychiatrist for nerves, anxiety, tension or depression	4.1	5.4	8.7	-2.4	-2.6	-2.1	-2.8	-1.8	-0.7	-2.9	-2.4	-2.2	-2.6	-2.4	-1.6	-2.7	-2.9	-2.6	1.5	-2.1	-2.2	-2.1	-2.8	-1.0	-2.2	-2.9
Comparative height size at age 10	4.1	22.5	38.1	-4.8	-5.0	-6.2	-5.0	-4.3	-2.1	-5.6	-4.1	-4.8	-5.0	-3.6	-4.9	-4.0	-5.8	-4.9	2.6	-5.0	-5.5	-5.7	-5.3	-5.3	-3.9	-3.4
Average weekly spirits intake	3.9	4.8	12.0	2.5	2.4	1.9	2.1	1.6	1.3	3.2	2.8	1.9	2.3	3.5	1.0	2.5	2.5	2.2	-1.6	1.6	1.3	2.2	3.0	0.5	1.6	2.3
Gout (self-reported)	3.9	5.3	13.6	-1.9	-2.5	-2.1	-2.5	-2.7	-2.0	-2.3	-1.6	-2.5	-2.0	-1.5	-2.2	-2.9	-1.7	-2.5	-1.1	-2.2	-1.8	-2.0	-1.4	-2.3	-3.7	-3.6
Family relationship satisfaction	3.8	4.7	9.2	-2.5	-2.5	-2.5	-2.3	-1.9	0.1	-2.8	-3.0	-2.2	-2.4	-2.1	-1.3	-2.3	-2.9	-2.2	2.4	-2.0	-1.7	-1.8	-2.2	-0.4	-1.5	-1.9
Impedance of leg (left)	3.7	18.0	56.0	-5.1	-4.3	-3.6	-3.6	-1.8	-0.9	-7.1	-7.5	-2.7	-4.6	-4.7	-0.7	-4.2	-6.5	-4.1	6.1	-2.4	-2.4	-3.7	-4.7	1.5	-1.8	-3.9
Forced vital capacity (FVC)	3.7	14.2	21.9	-3.6	-4.2	-4.4	-4.2	-3.3	-2.8	-4.1	-2.6	-4.1	-3.4	-4.2	-3.7	-3.8	-3.7	-4.0	1.3	-4.1	-3.8	-4.0	-4.7	-3.9	-3.6	-3.6
Neuroticism score	3.7	7.8	14.6	-3.3	-2.7	-3.2	-2.9	-3.0	-1.5	-2.7	-2.1	-2.6	-3.8	-2.6	-2.6	-2.6	-3.1	-2.6	0.6	-2.5	-2.9	-2.6	-2.6	-3.2	-3.5	-3.2
Leg fat percentage (left)	3.7	13.4	21.1	2.9	4.5	3.5	4.2	3.8	1.5	4.1	3.1	4.4	3.3	3.0	4.1	4.1	3.4	4.6	-2.8	4.0	4.0	3.4	4.1	2.4	3.4	3.8
Birth weight	3.6	7.8	14.0	-2.4	-2.9	-3.7	-3.1	-2.8	-2.8	-3.0	-0.3	-3.2	-2.6	-2.2	-3.4	-2.4	-2.2	-2.8	1.6	-3.2	-3.5	-3.1	-2.8	-3.5	-2.5	-2.0
Leg fat percentage (right)	3.6	13.1	21.2	2.6	4.5	3.6	4.2	3.8	1.8	3.9	3.1	4.4	3.1	2.9	4.2	4.1	3.3	4.6	-2.4	4.0	3.9	3.4	4.0	2.6	3.5	3.9
Impedance of leg (right)	3.5	16.8	51.6	-5.1	-4.0	-3.4	-3.4	-1.7	-0.6	-7.0	-7.2	-2.5	-4.5	-4.7	-0.5	-3.8	-6.3	-3.8	6.1	-2.2	-2.4	-3.8	-4.5	1.5	-1.6	-3.5
Hand grip strength (right)	3.5	9.4	19.8	-3.5	-3.4	-3.7	-3.3	-2.2	-2.6	-3.6	-1.2	-3.2	-3.0	-3.3	-3.0	-2.9	-2.4	-3.3	3.7	-3.1	-3.1	-4.4	-3.6	-1.8	-2.2	-2.2
Alcohol intake versus 10 years previously	3.5	5.2	10.7	1.9	2.8	2.6	2.5	1.1	1.1	2.3	2.3	2.4	2.3	3.0	1.2	2.6	2.6	2.5	-2.2	2.7	2.0	1.6	3.3	0.2	1.9	2.6
Irritable Bowel Disease (IBD)	3.4	8.2	11.3	-3.1	-3.0	-3.3	-3.2	-3.1	-2.5	-2.9	-1.4	-3.1	-3.3	-2.6	-3.1	-3.0	-2.5	-3.2	1.9	-3.4	-2.8	-2.3	-2.8	-2.6	-2.9	-3.0
Chest pain or discomfort	3.3	4.8	8.1	-2.3	-2.5	-2.3	-2.5	-2.4	-2.1	-2.3	-2.5	-2.3	-2.6	-2.1	-1.8	-2.4	-2.8	-2.2	1.7	-2.0	-1.8	-1.6	-2.1	-0.8	-2.1	-2.5
Hearing aid user	3.3	3.7	11.1	2.3	2.0	1.6	1.9	1.6	1.3	2.8	2.6	1.7	2.6	2.1	0.8	2.0	2.5	1.8	-3.3	1.0	1.3	1.3	1.8	-0.5	1.0	1.6
Basal cell carcinoma (self-reported)	3.3	3.9	7.9	-2.7	-2.0	-2.1	-2.0	-1.2	-0.5	-2.3	-2.6	-1.7	-2.8	-2.5	-0.9	-2.1	-2.6	-1.8	2.7	-1.9	-1.6	-1.1	-2.3	0.2	-1.1	-1.8
Myopia	3.2	4.6	8.7	1.8	2.4	2.1	2.6	2.1	2.4	1.8	2.0	2.4	1.6	1.1	1.8	2.0	2.4	2.1	-0.5	2.1	1.7	2.9	2.1	2.3	3.0	2.6
Eye problems/disorders: None of the above	3.1	3.6	6.2	1.5	1.9	2.5	1.9	2.3	1.2	1.8	1.4	2.0	1.8	2.1	2.1	2.0	1.6	1.8	0.2	2.2	1.5	1.9	2.0	2.2	2.3	2.2
Heel bone mineral density (BMD) T-score, automated (right)	3.0	6.8	12.3	1.6	3.0	3.1	2.7	2.2	1.4	1.9	1.4	2.9	2.2	2.7	2.9	2.8	2.8	3.4	-2.3	3.0	3.5	2.6	3.4	1.8	2.3	2.4
Forced expiratory volume in 1-second (FEV1), Best measure	3.0	9.5	14.7	-2.7	-3.3	-3.5	-3.4	-2.5	-2.6	-3.4	-0.8	-3.5	-2.8	-3.8	-3.2	-3.0	-2.8	-3.1	1.2	-3.5	-3.5	-3.1	-3.8	-3.5	-2.9	-2.8
Waist Hip Ratio (WHR)	2.9	13.2	72.2	-2.2	-2.4	-1.4	-1.5	0.9	1.0	-8.1	-8.5	0.0	-2.4	-5.0	2.7	-2.6	-6.8	-1.9	3.5	0.4	1.0	-1.5	-3.0	4.8	0.3	-2.8
Heel bone mineral density (BMD) T-score, automated (left)	2.9	6.5	11.6	1.6	3.0	3.0	2.8	2.4	1.2	2.2	1.6	3.0	2.0	2.1	2.8	3.0	2.4	3.3	-2.7	3.0	3.4	2.5	2.8	1.4	2.4	2.6
Pulse rate	2.9	4.8	20.6	-2.3	-1.9	-1.4	-1.7	-1.5	-0.4	-3.6	-4.5	-1.1	-2.1	-3.6	-0.4	-2.3	-3.4	-2.0	2.3	-1.0	-0.9	-1.7	-2.0	1.9	-0.8	-2.1
Comparative body size at age 10	2.9	7.9	11.0	3.2	3.2	3.1	2.9	2.9	2.1	2.8	2.6	3.0	3.0	2.5	2.7	3.1	3.0	3.3	-2.0	2.7	2.0	2.7	2.9	1.8	3.1	3.1
Migraine (self-reported)	2.9	3.6	5.5	-1.8	-2.3	-2.3	-2.0	-2.0	-1.4	-1.6	-1.9	-2.1	-1.7	-1.7	-2.0	-2.2	-2.0	-2.1	1.8	-1.7	-1.9	-1.2	-2.1	-1.4	-2.0	-1.7
Ulcerative Colitis (UC)	2.8	5.2	9.5	-2.3	-2.2	-2.6	-2.5	-2.5	-2.2	-1.8	-1.1	-2.3	-2.3	-2.2	-2.6	-2.3	-1.7	-2.5	-0.7	-2.7	-2.1	-1.6	-1.9	-3.0	-3.1	-2.9
Heel T-Score	2.8	22.6	47.7	3.2	5.7	4.9	5.9	4.9	1.5	3.2	2.5	5.9	3.6	3.3	5.2	5.8	4.0	5.9	-4.2	6.5	6.9	3.5	5.0	3.8	4.7	5.2
Blood Red Count	2.7	26.6	61.2	-6.7	-5.9	-5.1	-5.4	-2.6	-2.3	-7.2	-7.8	-4.3	-6.1	-5.3	-1.9	-6.2	-7.5	-5.4	3.5	-3.6	-2.9	-4.4	-5.3	-0.3	-4.7	-6.2
Emphysema/chronic bronchitis	2.7	3.0	8.5	-0.5	-1.8	-1.9	-2.0	-2.9	-0.8	-1.0	-1.5	-2.2	-0.9	-0.8	-2.6	-1.7	-1.1	-2.0	-0.0	-2.4	-2.1	-0.9	-0.9	-2.3	-2.1	-1.7
Type 2 Diabetes (T2D) (2012)	2.6	2.9	7.9	1.9	1.6	0.7	1.6	1.9	2.8	0.8	-0.5	1.9	1.8	2.1	2.4	1.0	0.6	1.9	-1.8	1.8	2.2	1.7	2.2	1.8	1.1	0.7
Average weekly fortified wine intake	2.6	3.0	6.2	-1.6	-1.8	-2.2	-1.9	-1.4	-1.5	-1.8	-0.1	-1.7	-1.8	-1.7	-2.2	-1.4	-1.2	-2.1	0.5	-1.9	-1.9	-2.4	-2.5	-2.2	-1.3	-1.0
Pulse wave reflection index	2.6	3.3	12.2	2.4	2.0	1.2	1.9	1.6	1.2	3.0	3.5	1.6	1.4	1.5	1.1	2.1	1.7	2.0	-2.4	0.9	0.4	1.7	1.3	-0.3	1.3	1.8
Forced expiratory volume in 1-second (FEV1)	2.5	8.5	15.0	-2.5	-3.1	-3.4	-3.2	-2.4	-2.1	-3.2	-1.0	-3.2	-2.5	-3.5	-3.0	-2.7	-2.6	-3.0	0.7	-3.2	-3.1	-3.2	-3.9	-3.7	-2.7	-2.6
Knee pain experienced in last month	2.5	3.9	6.5	1.4	2.4	2.2	2.1	2.5	1.3	2.0	1.8	2.4	1.5	2.3	2.0	2.4	1.2	2.5	-1.3	2.5	1.8	1.2	2.3	1.0	1.8	2.2
Eye problems/disorders: Cataract	2.5	2.9	5.9	-1.7	-1.8	-1.7	-1.7	-2.0	-1.8	-1.7	-1.9	-1.6	-2.2	-2.4	-1.9	-1.8	-1.0	-1.7	0.4	-1.6	-1.0	-1.3	-1.5	-1.6	-1.9	-1.8
Age started oral contraceptive pill	2.5	3.2	7.5	-1.9	-1.8	-1.1	-1.8	-2.0	-1.4	-1.3	0.1	-2.2	-2.1	-1.0	-2.5	-1.4	-0.7	-1.9	1.2	-1.7	-2.2	-2.1	-1.9	-2.7	-2.0	-1.6
Frequency of unenthusiasm / disinterest in last 2 weeks	2.4	3.3	6.5	-1.4	-1.9	-2.1	-1.9	-1.9	-0.6	-2.5	-1.4	-1.8	-1.8	-1.9	-2.0	-1.8	-2.0	-2.0	0.8	-2.0	-2.0	-1.4	-1.8	-1.7	-1.8	-2.0
Worry too long after embarrassment	2.4	4.0	8.9	-2.2	-1.9	-1.9	-1.8	-1.5	-0.0	-2.7	-2.5	-1.4	-2.7	-2.8	-0.6	-2.0	-3.0	-2.0	1.5	-1.8	-1.7	-0.6	-3.0	-0.8	-1.6	-2.3
Medication for cholesterol	2.4	3.6	8.9	-0.9	-2.2	-2.3	-2.1	-2.1	-3.0	-1.1	-0.8	-2.3	-0.9	-1.5	-2.7	-1.9	-0.9	-2.2	0.7	-2.0	-1.5	-1.6	-1.7	-2.4	-2.5	-2.1
HDL Cholesterol	2.3	3.8	9.2	-0.7	-1.9	-2.0	-2.0	-2.7	-2.6	-1.2	0.9	-2.5	-1.3	-1.2	-3.0	-1.5	-0.2	-1.9	2.0	-2.2	-2.5	-1.8	-1.9	-2.9	-1.8	-1.3
Alcohol usually taken with meals	2.3	3.8	8.3	-1.9	-2.1	-1.2	-1.9	-1.0	0.0	-2.6	-1.6	-1.8	-2.1	-2.4	-1.5	-1.8	-2.3	-2.4	2.6	-1.8	-2.1	-2.7	-2.9	-0.1	-1.1	-1.5
Arm fat percentage (right)	2.3	9.2	15.9	2.8	3.7	2.9	3.4	2.9	1.0	4.0	3.4	3.3	3.1	2.6	2.7	3.3	3.1	3.7	-3.2	3.1	3.1	2.8	3.4	1.1	2.3	3.1
Tinnitus: Yes, now most or all of the time	2.3	2.7	5.5	-0.9	-1.9	-2.4	-1.7	-1.3	-1.2	-1.8	-1.3	-1.6	-0.9	-1.5	-1.5	-1.8	-1.9	-2.0	0.0	-2.0	-2.3	-1.4	-1.1	-0.8	-2.1	-2.3
Diabetes (father)	2.2	2.7	4.8	1.5	1.8	1.5	1.7	2.2	0.8	1.7	1.0	2.0	1.4	1.0	2.1	1.7	1.1	1.9	-1.4	1.8	1.9	2.2	1.6	1.9	1.7	1.2
Length of working week for main job	2.2	2.5	6.4	0.9	1.6	1.5	1.1	0.9	-0.7	2.5	2.1	1.1	0.3	2.1	1.0	1.5	2.0	2.1	-2.0	1.6	1.6	1.5	2.4	-0.8	0.4	1.4
Medication: Paracetamol	2.2	3.6	7.9	-2.3	-2.2	-1.3	-1.9	-1.1	-0.6	-2.1	-2.8	-1.7	-2.4	-1.9	-0.9	-2.5	-2.5	-2.1	2.3	-1.7	-2.1	-1.3	-1.9	0.9	-1.2	-2.2
Leg fat mass (right)	2.2	8.6	16.0	2.4	3.6	2.5	3.2	2.9	0.9	3.8	4.0	3.2	2.3	2.6	2.4	3.5	3.1	3.7	-3.2	2.9	2.7	2.4	3.2	0.3	2.4	3.4
Mineral and other dietary supplements	2.2	2.9	6.0	-1.9	-1.8	-2.0	-1.9	-1.9	-1.6	-1.6	-2.5	-1.4	-1.8	-1.9	-0.9	-2.0	-2.0	-1.8	1.3	-1.6	-0.9	-0.7	-2.0	-0.2	-1.5	-2.0
Leg fat mass (left)	2.2	8.5	16.0	2.5	3.6	2.5	3.1	2.8	0.7	3.9	4.0	3.2	2.4	2.7	2.3	3.4	3.1	3.6	-3.5	2.9	2.7	2.3	3.2	0.1	2.2	3.3
Age at First Birth	2.1	3.1	11.3	2.2	1.5	1.4	1.2	0.2	2.2	1.6	2.5	0.8	1.8	3.4	-0.7	1.5	3.0	1.2	-1.9	0.9	0.6	1.8	2.4	-1.6	0.7	1.5
Cardiovascular Disease	2.1	7.0	14.9	3.5	3.0	2.0	2.5	2.2	0.6	2.7	3.6	2.4	3.3	2.8	1.7	3.2	3.3	3.2	-3.9	2.0	2.1	0.9	3.2	-0.1	1.6	2.7
Relative age voice broke	2.1	3.2	6.2	2.1	2.0	1.8	1.9	1.2	1.4	1.9	1.5	1.7	1.7	1.7	1.4	1.7	2.5	2.0	-0.2	1.5	1.4	2.2	2.2	1.8	2.3	2.0
Stomach or abdominal pain in last month	2.1	2.7	6.6	-1.1	-2.0	-1.1	-2.1	-1.3	-0.4	-2.6	-2.5	-1.5	-1.3	-1.2	-1.1	-2.2	-1.9	-2.1	1.8	-1.2	-1.2	-1.7	-1.2	0.4	-1.4	-2.0
Arm fat percentage (left)	2.1	8.4	15.7	2.7	3.5	2.7	3.2	2.7	0.9	4.0	3.2	3.2	3.0	2.4	2.6	3.1	2.8	3.6	-3.3	2.9	2.8	2.8	3.3	1.0	2.1	2.8
Mood swings	2.1	3.9	11.3	-2.0	-1.6	-2.3	-1.7	-2.1	-2.6	-1.3	-0.2	-1.8	-2.5	-1.3	-2.5	-1.2	-1.5	-1.5	-1.3	-1.6	-1.4	-2.7	-1.4	-3.4	-2.8	-1.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.1	2.4	6.2	-1.9	-1.5	-1.6	-1.2	-1.2	-1.9	-0.8	0.0	-1.7	-2.3	-1.0	-1.7	-1.1	-1.4	-1.0	-0.4	-1.3	-0.9	-2.3	-1.5	-2.5	-2.2	-1.6
Pain type(s) experienced in last month: Hip pain	2.1	2.7	6.0	1.3	1.9	1.7	1.8	2.2	2.1	1.3	0.9	2.0	1.0	1.1	2.5	1.4	0.6	1.9	-0.7	1.6	1.5	1.9	1.6	2.0	1.8	1.4
Body Mass Index (BMI) (2010)	2.0	2.8	5.1	0.7	2.2	1.3	1.8	1.7	1.5	1.9	2.2	2.0	0.3	1.2	1.5	2.2	1.7	2.3	-1.5	1.8	1.4	1.4	1.8	0.0	1.4	2.2
Frequency of tiredness / lethargy in last 2 weeks	2.0	3.2	5.2	-1.7	-2.0	-1.6	-2.1	-1.9	-0.1	-1.9	-2.1	-1.8	-2.0	-1.7	-1.4	-2.0	-2.3	-1.8	1.0	-1.9	-1.8	-1.6	-2.0	-1.3	-1.8	-2.1
Qualifications: College or University degree	2.0	6.4	14.7	-3.2	-2.8	-2.0	-2.1	-2.4	-1.2	-3.3	-3.0	-2.4	-3.8	-3.1	-2.0	-3.1	-2.5	-2.8	2.9	-2.0	-2.2	-0.8	-3.3	-0.5	-1.2	-2.3
Medication: Allopurinol	2.0	2.7	6.7	-1.6	-1.6	-1.5	-1.5	-2.1	-1.3	-1.9	-1.8	-1.6	-1.6	-1.1	-1.3	-1.8	-1.3	-1.6	-0.7	-1.5	-1.2	-1.7	-0.7	-1.7	-2.6	-2.6
Crohns Disease (2017)	1.9	4.1	11.0	-2.3	-2.1	-2.3	-2.2	-2.1	-1.7	-2.0	-0.7	-2.1	-2.5	-1.4	-2.2	-2.0	-1.9	-2.2	3.3	-2.3	-2.2	-1.7	-2.2	-1.1	-1.1	-1.3
Multivitamins +/- minerals	1.9	2.4	6.5	2.0	1.7	1.5	1.7	1.5	0.7	0.7	2.5	1.2	1.9	1.9	0.5	1.9	2.4	1.5	-0.2	1.3	1.1	0.6	2.1	0.4	1.7	1.9
Depressed Affect (Nagel 2018)	1.8	3.8	11.2	-2.0	-1.7	-1.9	-2.0	-2.3	-1.6	-0.9	-0.1	-2.1	-2.4	-1.0	-2.5	-1.4	-1.4	-1.5	-0.7	-1.7	-2.2	-2.5	-1.0	-3.3	-3.0	-2.0
Primary Biliary Cirrhosis	1.8	2.6	4.4	1.4	1.8	1.9	1.8	1.2	1.1	1.5	1.5	1.6	1.4	2.0	1.2	1.7	1.9	1.7	-0.4	1.6	1.5	2.1	1.8	1.1	1.8	2.0
Serious illness, injury or assault of a close relative in last 2 years	1.8	2.0	5.7	-1.3	-1.7	-0.4	-1.8	-1.1	0.1	-2.1	-1.8	-1.5	-1.7	-1.2	-0.9	-2.0	-1.4	-1.7	2.4	-0.8	-1.0	-1.2	-1.4	1.1	-0.6	-1.3
Pulse wave peak to peak time	1.8	2.1	5.7	-1.7	-1.5	-1.4	-1.4	-1.3	-1.7	-2.4	-1.5	-1.3	-1.5	-1.0	-1.5	-1.2	-1.2	-1.6	1.8	-0.7	-0.9	-1.9	-1.2	-1.2	-1.3	-1.1
Mouth/teeth dental problems: Mouth ulcers	1.8	2.9	5.9	1.2	2.0	1.5	1.8	1.6	0.7	1.4	1.2	2.0	1.0	2.1	1.5	1.9	1.1	2.1	-2.1	2.4	1.9	2.2	2.1	0.6	1.5	1.8
Smoking status: Current	1.8	2.8	5.1	1.4	2.1	2.2	2.0	1.4	0.8	2.0	0.7	1.8	1.2	1.1	2.0	2.0	1.6	2.2	-1.2	1.7	1.8	1.7	1.7	1.2	1.6	1.9
Arm fat mass (left)	1.8	7.3	15.3	2.6	3.2	2.2	2.8	2.3	0.6	3.9	3.9	2.7	2.7	2.4	1.8	3.1	3.0	3.2	-3.7	2.4	2.3	2.2	2.9	-0.3	1.8	2.9
Triglycerides	1.7	2.8	7.2	-0.2	1.8	2.0	1.6	2.7	2.2	0.8	-0.3	2.4	0.1	0.8	2.6	1.5	-0.4	1.7	-0.9	2.3	2.0	0.5	1.1	2.4	1.9	1.5
Hair/balding pattern: Pattern 4	1.7	4.2	7.3	2.5	2.4	1.7	2.3	1.9	2.2	2.3	2.4	2.2	2.5	2.4	1.7	2.5	1.8	2.4	-1.0	1.8	0.8	0.7	1.9	0.9	2.2	2.7
Number of full brothers	1.7	2.2	5.6	1.9	1.5	1.6	1.7	1.3	1.1	2.3	1.4	1.3	1.4	0.6	1.1	1.4	1.5	1.5	-0.9	1.2	1.1	2.4	1.3	1.2	1.4	1.5
Pulse rate, automated reading	1.7	5.6	36.6	-1.0	0.1	1.4	0.6	0.8	2.4	-2.9	-5.0	1.4	-0.2	-2.1	3.5	-0.9	-2.5	0.4	3.2	1.9	1.6	1.3	-0.2	6.0	2.3	-0.1
Long-standing illness, disability or infirmity	1.7	2.6	5.7	0.7	2.1	2.0	2.0	1.9	1.8	1.0	0.4	2.2	0.6	1.0	2.2	1.8	0.9	1.9	-2.4	1.8	1.7	1.4	1.2	0.9	1.6	1.5
Ever had bowel cancer screening	1.7	1.9	5.6	-1.3	-1.2	-1.8	-1.3	-1.2	-0.9	-2.4	-1.0	-1.4	-1.1	-2.1	-1.4	-0.8	-1.3	-1.2	0.9	-1.5	-1.0	-1.6	-1.7	-1.8	-1.2	-0.9
Ever taken oral contraceptive pill	1.7	1.9	6.7	1.8	1.4	1.0	1.4	1.0	1.2	1.6	1.5	1.3	1.5	0.6	1.2	1.3	1.4	1.5	-2.6	0.8	1.4	2.0	1.3	0.3	1.0	1.1
Crohns Disease (2012)	1.6	2.5	12.0	-1.5	-1.6	-1.7	-1.5	-1.2	-0.9	-1.7	-1.1	-1.4	-1.7	-1.3	-0.9	-1.4	-2.1	-1.5	3.5	-1.4	-1.9	-1.5	-2.0	-0.1	-0.4	-0.8
Blood White Count	1.6	11.7	31.9	1.9	3.6	3.9	3.7	4.3	3.2	1.0	-0.5	4.3	2.5	1.3	5.7	3.1	1.2	3.9	-1.4	4.1	4.6	2.9	3.0	5.2	4.0	3.0
Medication: Metformin	1.6	2.2	4.0	1.9	1.8	1.0	1.8	1.2	0.9	1.4	1.9	1.6	1.3	0.8	1.2	1.8	1.8	1.8	-2.0	1.2	1.5	1.6	1.6	0.5	1.1	1.5
Hayfever/allergic rhinitis (self-reported)	1.6	2.1	3.7	-1.7	-1.4	-1.3	-1.4	-1.3	-1.6	-1.9	-1.8	-1.2	-1.4	-1.9	-0.8	-1.2	-1.7	-1.3	0.5	-1.1	-0.1	-1.9	-1.9	-1.0	-1.5	-1.5
Arm fat mass (right)	1.6	6.5	13.8	2.5	3.0	2.1	2.6	2.1	0.5	3.6	3.7	2.5	2.6	2.3	1.5	2.9	2.9	3.0	-3.5	2.3	2.2	2.0	2.7	-0.4	1.7	2.8
Medication: Paracetamol	1.5	2.3	4.1	-1.8	-1.7	-1.3	-1.6	-1.3	-1.2	-1.3	-1.5	-1.6	-2.0	-1.6	-1.3	-1.9	-1.4	-1.7	0.9	-1.8	-1.8	-1.0	-1.3	-0.3	-1.5	-1.8
Ever had prostate specific antigen (PSA) test	1.5	1.8	5.8	-0.2	-1.3	-1.4	-1.4	-1.2	-0.7	-0.3	0.9	-1.8	-0.4	-0.9	-1.9	-0.9	0.0	-1.2	-0.6	-2.0	-1.4	-1.7	-1.1	-2.4	-2.0	-1.3
Prostate Cancer	1.4	2.0	3.8	-1.3	-1.6	-1.4	-1.2	-1.0	-1.8	-1.1	-0.8	-1.6	-1.3	-0.9	-1.9	-1.4	-1.2	-1.6	0.5	-1.3	-1.6	-1.9	-1.1	-1.6	-1.9	-1.4
Rheumatoid Arthritis	1.4	2.0	3.9	1.6	1.7	1.1	1.5	0.5	0.4	0.8	0.8	1.5	1.9	1.6	1.1	1.9	1.6	1.7	-0.2	1.6	1.8	1.2	1.5	0.6	1.7	2.0
Osteoarthritis (self-reported)	1.4	1.8	4.0	1.3	1.4	2.0	1.4	1.4	0.8	1.6	0.9	1.4	1.4	1.8	1.5	1.3	1.1	1.5	-0.4	1.6	1.4	0.1	1.7	0.9	1.1	1.2
Medication: Gliclazide	1.4	1.6	2.8	1.5	1.3	1.1	1.3	1.5	0.9	0.8	0.5	1.5	1.3	0.5	1.6	1.4	0.4	1.4	-1.4	1.5	1.7	1.4	0.9	1.3	1.4	1.3
Breast Cancer	1.3	3.1	8.5	1.2	2.2	1.5	2.0	1.4	1.5	2.9	1.4	2.2	1.7	1.6	1.6	1.7	1.7	1.9	-0.2	1.7	0.5	2.7	1.3	1.1	2.2	2.1
Mean Putamen Volume	1.3	1.5	6.1	-0.6	-1.2	-1.3	-0.9	-1.8	0.1	-1.1	-2.5	-1.2	-0.7	-1.0	-0.8	-1.2	-1.7	-1.1	1.9	-1.2	-1.7	-0.7	-1.1	-0.4	-0.9	-1.1
Blood Platelet Count	1.3	14.8	27.0	3.6	4.3	5.2	3.7	2.9	2.5	4.4	4.2	3.7	5.0	3.2	3.4	3.3	5.0	4.0	-1.9	3.5	3.6	4.3	4.6	3.1	3.4	3.6
Tanning	1.3	15.3	25.7	4.6	4.4	3.7	4.2	2.9	2.2	5.1	4.9	3.4	4.7	4.2	2.6	4.5	4.9	4.5	-3.2	3.4	3.3	3.1	4.8	0.6	3.2	4.4
Diabetes (mother)	1.3	1.6	5.6	0.1	1.2	1.3	1.3	1.2	1.3	-0.3	-1.0	1.7	-0.2	0.4	2.0	0.9	0.1	1.3	-0.3	2.0	2.0	1.1	0.8	2.4	1.6	1.0
Heart attack	1.3	1.7	3.7	0.6	1.7	1.9	1.4	1.2	0.9	1.0	1.1	1.6	0.8	0.1	1.3	1.6	1.4	1.6	-1.3	1.7	1.7	1.0	1.3	0.3	1.0	1.5
Medication: Cholesterol lowering	1.3	2.0	6.7	1.6	1.5	1.7	1.1	0.7	0.6	1.7	2.3	1.1	1.7	1.2	0.6	1.5	2.6	1.5	-1.5	1.2	1.4	0.6	1.8	-0.0	0.8	1.4
Loud music exposure frequency	1.3	1.4	3.1	-1.0	-1.4	-1.4	-1.8	-1.6	-0.2	-0.9	-0.8	-1.6	-1.1	-0.4	-1.1	-1.6	-0.8	-1.2	0.9	-1.5	-1.4	-0.8	-0.8	-0.5	-1.5	-1.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.3	1.5	2.3	0.6	1.4	1.4	1.3	1.4	1.4	1.5	1.3	1.4	0.4	1.3	1.5	1.4	1.1	1.4	-1.4	1.2	1.3	0.6	1.1	0.9	1.0	1.1
Commuting to job workplace: Walk	1.3	1.4	6.8	1.6	0.5	1.6	1.0	1.4	1.1	0.8	-0.4	0.8	2.3	1.1	0.9	0.2	0.5	0.4	-0.0	0.9	1.2	1.0	1.2	2.6	1.1	0.3
Illnesses of father: High blood pressure	1.3	1.6	4.0	-0.2	-1.4	-1.0	-1.6	-1.9	-1.4	-0.1	0.2	-1.7	-0.2	-0.1	-2.0	-1.6	0.6	-1.4	-0.4	-1.5	-1.5	-0.8	-0.4	-1.6	-1.9	-1.7
Medication for hormone replacement therapy	1.2	1.3	7.2	-0.0	0.9	1.2	0.9	1.6	1.8	0.1	-0.4	1.1	0.2	0.8	2.1	0.5	-0.1	1.1	0.2	1.2	1.4	0.7	0.4	2.7	1.4	0.7
Current tobacco smoking	1.2	2.0	3.8	1.4	1.7	1.9	1.8	1.1	0.7	1.6	0.4	1.5	1.1	0.9	1.9	1.7	1.1	2.0	-0.8	1.4	1.5	1.5	1.4	1.1	1.3	1.5
Qualifications: None of the above	1.2	2.6	11.4	1.3	1.6	0.6	1.1	0.1	-0.2	2.4	1.8	0.8	0.9	2.4	-0.2	1.8	2.0	1.7	-3.4	0.7	0.4	-0.2	3.2	-1.9	-0.7	0.7
Time employed in main current job	1.2	1.4	3.5	1.3	1.2	1.2	0.9	1.3	0.8	0.4	0.2	1.3	1.8	0.7	1.6	0.9	0.9	1.1	-0.2	1.1	1.6	1.8	1.4	1.9	0.9	0.5
Falls in the last year	1.2	1.6	5.4	0.4	1.4	0.7	1.2	0.3	1.9	0.8	-1.1	1.4	0.3	0.4	2.3	1.0	-0.1	1.9	-0.6	1.0	1.1	2.1	1.3	1.7	1.4	1.1
Mouth/teeth dental problems: Bleeding gums	1.2	1.6	10.2	-1.7	-1.1	-0.8	-1.1	-0.7	-0.1	-0.9	-3.2	-0.6	-2.1	-0.4	0.6	-1.4	-2.2	-0.7	1.6	-0.1	-0.5	-0.0	-1.0	0.9	-0.5	-1.0
Back pain experienced in last month	1.2	1.8	6.0	1.1	1.4	1.4	1.0	0.9	0.3	1.1	2.1	1.0	0.9	2.5	0.2	1.7	1.5	1.4	-1.9	1.0	0.6	0.9	1.7	-1.2	0.5	1.4
Medication: Lisinopril	1.2	1.6	6.6	0.3	1.2	1.7	0.7	1.6	-0.0	1.2	1.1	1.4	0.5	0.3	1.5	1.2	1.7	1.4	-2.6	1.6	1.7	1.0	1.0	0.5	0.5	0.9
Alcohol drinker status: Never	1.2	1.5	3.4	-0.8	-1.4	-0.7	-1.3	-1.1	-0.4	-0.8	-1.1	-1.3	-0.8	-1.4	-1.1	-1.4	-1.1	-1.3	0.6	-1.2	-1.4	-1.9	-1.1	-1.2	-1.8	-1.6
Systolic blood pressure, automated reading	1.1	3.1	13.1	2.1	0.9	0.6	0.0	-0.3	-0.4	3.1	3.2	-0.2	2.6	2.5	-1.0	1.0	2.8	0.9	-3.6	-1.0	0.1	0.4	1.9	-2.0	-0.9	0.3
Age when periods started (menarche)	1.1	2.7	14.0	0.2	0.7	0.8	0.3	-1.1	-2.9	1.5	3.5	-0.5	0.1	1.0	-2.3	1.2	3.1	0.5	-1.3	-0.1	-0.3	-0.1	1.3	-3.7	-0.6	1.2
Medication: Atenolol	1.1	1.3	2.5	0.8	1.2	1.4	1.2	1.1	1.1	1.2	1.0	1.2	1.0	0.9	1.6	1.2	1.4	1.3	-0.7	1.0	1.6	0.9	1.2	1.0	0.9	1.0
Body fat percentage	1.1	4.3	8.0	1.2	2.7	1.8	2.5	2.3	0.6	2.4	1.8	2.7	1.6	1.5	2.4	2.5	1.5	2.8	-2.0	2.5	2.3	1.8	2.2	0.9	1.8	2.3
Ever had stillbirth, spontaneous miscarriage or termination	1.1	1.2	2.8	0.3	1.3	0.8	1.2	1.4	1.0	0.5	0.2	1.5	0.6	1.0	1.7	1.4	0.6	1.5	-1.5	1.2	1.6	0.2	1.0	0.5	0.9	1.1
Supplements: Fish oil (including cod liver oil)	1.1	1.5	5.3	1.7	1.0	1.0	1.0	0.9	1.2	0.9	2.3	0.4	1.6	1.4	-0.0	1.4	2.0	1.0	-1.4	0.5	0.7	-0.1	1.6	-1.1	0.4	1.1
Heart attack/myocardial infarction (self-reported)	1.1	1.4	3.3	0.4	1.5	1.8	1.2	1.3	0.9	0.8	0.9	1.5	0.5	0.1	1.2	1.4	1.2	1.4	-1.2	1.6	1.6	0.9	1.1	0.4	0.9	1.2
Chronotype (morning person)	1.0	2.4	7.7	0.7	1.8	1.3	1.3	2.0	1.7	0.7	2.3	1.5	1.3	1.1	1.3	2.0	1.4	1.7	-2.8	1.1	2.0	-0.2	1.5	-0.2	1.0	1.5
Sensitivity / hurt feelings	1.0	1.7	5.3	-1.8	-1.1	-1.1	-1.0	-1.1	-0.4	-2.3	-1.9	-0.7	-2.1	-2.1	-0.3	-1.2	-1.6	-1.1	0.9	-0.7	-0.6	-0.5	-1.4	-0.5	-1.0	-1.4
Ever used hormone-replacement therapy (HRT)	1.0	1.2	5.0	0.2	0.8	1.6	0.7	1.9	2.2	0.6	0.3	1.0	0.2	0.8	1.9	0.3	-0.1	0.8	0.1	0.8	1.0	0.7	0.7	2.2	1.2	0.3
Ever had hysterectomy (womb removed)	1.0	1.1	2.6	-0.3	1.2	1.3	0.8	1.4	1.1	0.1	1.4	1.1	0.0	1.2	1.2	0.7	1.0	1.1	-1.2	0.9	1.2	1.1	1.6	0.7	1.1	0.9
Hearing difficulty/problems with background noise	1.0	1.5	4.5	-0.7	-1.1	-2.1	-1.1	-1.5	-0.8	-1.6	-1.6	-1.1	-0.9	-1.3	-0.9	-1.1	-1.8	-1.1	0.1	-1.6	-1.4	0.0	-0.8	-1.0	-1.3	-1.4
Medication for cholesterol, blood pressure or diabetes	1.0	1.6	7.0	-1.5	-1.1	-1.2	-0.7	-0.2	0.6	-1.8	-2.5	-0.6	-1.5	-0.8	0.3	-1.1	-2.6	-0.8	2.2	-0.4	-1.0	-0.7	-1.3	0.9	-0.0	-0.8
Number of children fathered	1.0	1.2	3.0	0.1	1.3	1.3	1.3	1.7	0.6	1.1	1.5	1.3	0.1	0.9	0.8	1.3	1.0	1.0	-0.9	1.2	1.0	0.3	0.7	0.6	1.3	1.4
Medication: Blood pressure	1.0	1.8	7.6	1.1	0.9	1.0	0.5	-0.4	-1.8	1.8	2.3	0.4	0.9	0.7	-0.9	1.0	2.7	0.6	-2.7	0.3	0.9	0.7	1.2	-1.9	-0.6	0.5
Had major operations	1.0	1.2	3.4	1.7	0.9	1.5	0.9	-0.0	0.7	0.8	-0.2	0.6	1.6	1.2	0.6	0.7	1.4	0.9	0.2	0.9	0.9	1.2	1.8	1.9	1.2	0.8
Leg pain on walking	1.0	1.3	3.5	1.7	1.4	0.8	1.3	-0.0	-0.6	0.7	0.4	1.3	1.5	0.2	0.6	1.3	1.2	1.2	-1.9	0.9	1.7	1.2	1.4	0.2	0.8	1.0
Eye problems/disorders: Glaucoma	1.0	1.2	3.3	-0.7	-1.1	-1.8	-1.0	-1.4	-0.0	-1.3	-1.8	-0.9	-0.5	-1.2	-0.2	-1.3	-1.7	-0.9	1.0	-1.4	-0.8	-0.7	-0.9	0.1	-0.9	-1.4
High cholesterol (Self-reported)	1.0	1.8	5.3	1.6	1.4	0.6	0.9	0.3	1.2	1.3	2.3	0.9	1.6	1.8	0.4	1.4	2.0	1.4	-2.1	0.6	0.9	0.6	2.0	-0.8	0.3	1.0
HbA1C	0.9	1.0	4.0	0.1	1.1	1.0	1.0	0.6	0.4	0.7	1.0	0.9	0.1	1.2	0.5	1.2	0.8	1.2	-2.0	1.5	1.3	0.2	1.6	-0.1	0.1	1.0
Severe depression (siblings)	0.9	1.0	2.2	-0.8	-1.1	-0.7	-1.3	-0.3	-0.3	-1.5	-1.2	-0.8	-0.9	-1.5	-0.2	-1.2	-1.3	-1.0	1.4	-0.8	-1.0	-0.3	-1.4	0.6	-0.3	-1.0
High blood pressure (mother)	0.9	1.3	3.3	-0.3	-1.2	-0.9	-1.4	-0.7	0.4	-1.2	-1.2	-1.0	-0.6	-1.5	-0.3	-1.5	-1.3	-1.2	0.5	-1.5	-1.0	-1.8	-1.6	0.6	-0.9	-1.6
Hip circumference	0.9	3.8	18.4	1.3	2.1	1.5	1.6	1.3	-1.0	3.5	4.3	1.4	1.4	1.8	0.3	2.1	2.7	2.0	-2.3	1.2	0.6	1.4	1.7	-1.5	1.0	2.3
Lung cancer (father)	0.9	1.1	2.3	-0.4	-1.2	-0.9	-1.1	-0.7	-1.0	-1.0	-0.5	-1.1	-0.1	-0.9	-1.0	-1.1	-1.1	-1.4	0.6	-1.5	-1.0	-0.9	-1.4	-0.6	-1.3	-1.5
Pulse wave Arterial Stiffness index	0.9	1.0	3.5	1.2	1.0	0.8	0.9	0.9	1.4	1.9	1.2	0.8	1.1	0.7	0.9	0.7	0.7	1.0	-1.4	0.2	0.4	1.3	0.6	0.8	1.0	0.8
Peak expiratory flow (PEF)	0.9	2.1	6.9	-0.2	-1.4	-2.1	-1.5	-0.9	-0.3	-0.8	0.3	-1.7	-0.3	-1.3	-1.9	-0.8	-1.0	-1.4	-0.6	-1.9	-1.9	-1.9	-1.8	-2.6	-1.6	-1.1
Shortness of breath walking on level ground	0.9	1.0	4.8	1.7	1.0	-0.0	1.0	0.3	1.1	1.2	1.2	0.8	1.8	0.7	-0.0	1.1	0.7	1.0	-2.2	0.3	0.5	-0.5	1.4	-0.3	0.2	0.6
Loneliness, isolation	0.9	1.3	9.2	-0.9	-0.4	-1.1	-0.7	-1.5	-1.3	-0.0	0.0	-0.7	-1.7	-0.7	-1.6	-0.1	-0.6	-0.4	-1.3	-0.6	-1.2	-0.6	-0.2	-3.0	-1.7	-0.5
Wears glasses or contact lenses	0.9	1.0	6.2	-0.2	0.8	0.9	0.5	-0.4	-0.2	1.2	2.5	0.3	0.1	1.3	-1.1	0.9	2.3	0.4	-0.9	0.5	-0.3	0.2	0.9	-1.4	0.0	1.0
Mother’s age at death	0.9	1.1	2.3	-0.7	-1.2	-1.5	-1.2	-1.5	-0.5	-0.9	-0.3	-1.5	-0.2	0.3	-1.5	-1.0	-0.7	-1.0	1.5	-1.1	-1.0	-0.6	-0.9	-1.5	-1.0	-0.7
Medication: Bendroflumethiazide	0.9	1.3	5.0	1.3	1.2	1.2	0.6	0.9	0.4	1.4	2.2	0.8	1.4	1.3	0.4	1.2	1.6	1.1	-2.0	0.8	1.4	0.4	0.9	-0.3	0.6	1.0
Systolic Blood Pressure	0.8	4.0	20.7	2.5	1.7	1.4	0.8	0.7	0.6	2.7	3.3	0.7	2.6	2.7	0.5	1.8	3.1	1.9	-4.5	-0.0	1.0	0.9	2.2	-1.2	0.1	1.0
Maternal smoking around birth	0.8	1.2	3.8	1.6	1.0	0.7	1.0	0.4	0.6	0.9	-1.1	1.4	1.5	0.9	1.3	0.7	-0.1	1.0	-0.4	1.1	1.2	1.9	1.3	1.7	0.9	0.5
Bilateral oophorectomy (both ovaries removed)	0.8	0.9	4.4	0.8	1.0	1.0	0.7	1.0	2.0	0.3	0.5	1.0	0.9	0.7	1.1	0.6	0.1	0.8	0.2	0.3	0.4	0.4	1.0	2.1	1.2	0.4
Waist circumference	0.8	2.8	5.8	1.3	2.1	1.5	2.0	2.1	0.2	0.8	0.8	2.4	1.2	0.3	2.4	1.8	0.5	2.2	-2.0	2.2	2.1	1.8	1.4	1.2	1.6	1.6
Mouth/teeth dental problems: Loose teeth	0.8	1.0	2.6	-1.6	-0.9	-0.8	-1.0	-0.8	-1.5	-0.4	-1.1	-0.8	-1.6	-1.3	-0.4	-0.9	-1.0	-0.7	-0.1	-0.6	-0.7	-0.9	-1.1	-0.8	-1.0	-0.9
Hypertension (Self-reported)	0.8	2.1	7.3	1.8	1.3	0.9	0.7	0.2	-0.7	2.1	2.7	0.7	2.0	1.5	-0.1	1.4	2.7	1.3	-2.6	0.3	0.5	0.0	1.8	-1.1	-0.0	0.9
Financial situation satisfaction	0.8	1.0	4.8	0.6	1.2	0.3	1.0	0.4	-0.2	1.0	-0.3	1.1	0.6	0.2	1.2	1.4	0.2	1.5	-2.2	1.1	1.6	0.6	1.0	-0.2	0.7	1.0
Fasting Glucose	0.7	0.8	2.6	0.1	0.8	1.3	0.7	1.2	1.1	0.6	0.1	1.2	0.3	0.8	1.4	0.4	0.7	0.7	-1.0	0.9	0.9	0.9	1.1	1.6	0.6	0.3
Number of treatments/medications taken	0.7	1.3	4.9	0.8	1.2	1.5	0.9	0.9	0.9	1.2	1.8	0.9	0.9	1.0	0.8	0.9	1.9	1.1	-2.2	0.4	0.8	0.6	1.5	0.3	0.3	0.6
Eye problems/disorders: Diabetes related eye disease	0.7	0.7	2.6	1.0	0.8	0.3	1.0	0.7	0.6	0.7	0.1	0.9	0.8	0.2	1.0	0.7	0.9	0.9	-0.9	0.5	0.7	1.6	0.7	1.2	1.0	0.6
Serious illness, injury or assault to yourself	0.7	0.9	3.8	-1.4	-0.7	-0.4	-0.7	0.1	0.8	-2.0	-1.3	-0.2	-1.5	-0.2	-0.0	-1.1	-0.9	-1.0	1.3	-0.5	-0.6	-0.9	-0.4	1.3	0.1	-0.7
Trunk fat-free mass	0.7	3.8	25.6	-0.1	-0.9	-1.9	-1.3	-1.9	-2.3	0.1	2.7	-1.9	-1.0	-0.5	-3.5	-0.3	0.8	-1.1	-1.8	-2.1	-2.2	-1.9	-1.2	-5.1	-1.5	0.2
Hair/balding pattern: Pattern 3	0.7	1.0	2.1	0.4	1.2	1.3	1.2	1.2	0.6	0.5	0.4	1.2	0.6	0.6	1.0	1.2	0.8	1.2	-0.2	1.3	1.2	0.6	0.9	1.1	1.4	1.4
Noisy workplace	0.7	0.9	2.5	1.3	1.0	0.6	0.7	0.4	0.7	1.0	1.4	0.8	1.2	1.1	0.1	1.1	1.2	0.9	-1.6	0.5	0.5	0.1	1.4	-0.1	0.2	0.8
Illnesses of mother	0.7	0.8	2.0	0.1	1.0	1.3	1.2	1.0	-0.4	1.0	1.4	0.8	0.3	0.5	0.5	1.1	1.2	1.1	-0.8	1.0	0.5	1.2	1.0	-0.4	0.8	1.2
Trunk predicted mass	0.7	3.7	25.6	-0.0	-0.9	-1.9	-1.3	-1.9	-2.3	0.2	2.8	-1.9	-1.0	-0.4	-3.5	-0.2	0.8	-1.1	-1.9	-2.1	-2.1	-1.8	-1.1	-5.1	-1.5	0.2
Glaucoma (self-reported)	0.7	0.9	3.3	-0.5	-0.7	-1.1	-0.6	-0.4	1.0	-1.5	-1.8	-0.3	-0.3	-0.8	0.7	-1.0	-1.7	-0.5	1.2	-0.7	-0.2	-1.0	-0.6	0.7	-0.3	-1.2
Whole body fat mass	0.7	3.1	6.7	1.3	2.2	1.1	1.9	1.5	0.0	2.3	2.6	1.9	1.4	1.4	1.1	2.2	1.8	2.3	-2.6	1.7	1.6	1.1	1.8	-0.8	1.2	2.2
Illness, injury, bereavement, stress in last 2 years	0.7	0.9	4.6	1.1	-0.2	-0.8	-0.2	-1.1	-0.7	1.0	1.6	-0.9	1.1	0.3	-1.5	0.3	0.7	-0.2	-0.7	-1.4	-1.0	0.1	0.0	-2.1	-0.7	0.0
Average weekly champagne plus white wine intake	0.7	1.0	5.2	0.9	0.9	0.9	0.6	0.1	-0.5	2.1	2.3	0.2	0.7	0.8	-0.0	0.7	1.7	0.8	-0.2	-0.0	-0.0	1.7	1.0	-0.5	0.4	0.9
Vascular/heart problems diagnosed by doctor	0.7	1.8	7.1	-1.5	-1.4	-1.2	-0.8	-0.2	0.4	-2.0	-2.0	-0.8	-1.8	-1.3	-0.3	-1.4	-2.7	-1.4	2.2	-0.6	-0.9	-0.1	-1.9	0.7	-0.1	-1.0
Lung FEV1/FVC ratio	0.6	3.1	22.9	1.8	1.7	1.5	1.0	0.7	-0.3	1.6	4.8	0.6	1.5	1.2	-0.5	2.0	2.9	1.5	-2.2	0.4	0.4	0.1	1.2	-2.9	0.1	1.5
Supplements: Zinc	0.6	0.7	2.0	0.7	0.7	0.8	0.4	0.8	0.8	-0.2	0.2	0.7	0.5	1.0	1.3	0.6	1.3	0.8	-0.3	0.9	1.1	1.0	1.4	0.9	0.5	0.4
High blood pressure	0.6	1.7	6.7	1.4	1.2	0.7	0.5	-0.0	-0.6	1.9	2.4	0.5	1.7	1.5	-0.1	1.2	2.6	1.2	-2.1	0.2	0.5	-0.1	1.8	-1.0	-0.1	0.8
Hair/balding pattern: Pattern 2	0.6	0.8	4.1	1.3	0.5	0.7	0.6	0.5	-0.1	1.3	2.0	0.2	1.2	0.9	-0.3	0.7	1.6	0.6	-0.3	0.5	0.9	0.1	0.8	-0.6	0.2	0.6
Weight	0.6	3.0	14.1	1.4	1.8	0.4	1.3	0.9	-0.7	2.5	3.8	1.1	1.0	1.3	-0.2	2.0	2.0	1.8	-3.2	0.8	0.5	0.5	1.4	-2.5	0.6	2.1
Breastfed as a baby	0.6	0.8	1.6	1.0	1.1	0.5	1.1	0.3	-0.0	1.0	1.3	0.7	1.1	0.9	0.4	1.2	1.2	1.0	-0.0	0.9	0.5	0.7	1.3	0.2	1.0	1.2
Wheeze or whistling in the chest in last year	0.6	1.1	3.0	-0.6	-0.9	-1.7	-1.0	-1.2	-1.0	-1.1	-0.9	-1.0	-1.0	-0.7	-1.1	-0.7	-1.5	-0.8	-0.8	-1.1	-0.5	-1.4	-0.3	-1.3	-1.7	-1.2
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	3.4	-1.6	-0.4	-1.5	-0.2	0.1	-1.4	-1.0	-0.6	-0.2	-1.9	-1.0	0.1	-0.2	-1.1	-0.0	0.6	-0.0	-0.2	0.1	-0.6	-0.6	-0.2	-0.2
Medication for pain relief, constipation, heartburn	0.6	1.0	3.2	0.9	1.0	0.9	1.1	0.5	-0.6	0.6	0.9	0.9	1.5	0.7	0.5	1.1	1.2	0.9	-0.0	1.3	1.8	1.7	0.7	0.5	1.2	1.3
Angina (self-reported)	0.6	0.8	2.2	-0.8	-0.9	-0.4	-0.9	-1.2	-0.8	-0.3	0.0	-1.3	-0.9	-0.5	-1.5	-0.8	0.2	-0.9	0.4	-1.2	-0.9	-0.7	-0.7	-1.2	-1.3	-1.1
Irritability	0.6	1.1	5.4	0.2	1.1	1.1	0.7	0.5	-0.5	2.1	2.3	0.7	-0.2	0.8	0.1	1.1	1.5	1.0	-1.1	1.0	0.7	0.9	0.9	-1.0	0.0	0.8
Commuting to job workplace: Cycle	0.6	0.7	2.4	1.0	-0.3	0.4	-0.4	-1.1	0.4	0.2	0.7	-0.9	1.5	1.4	-1.5	-0.3	1.1	-0.4	-0.6	-0.4	0.0	-0.3	0.8	-1.4	-0.8	-0.3
Angina	0.5	0.7	1.9	-0.6	-0.8	-0.3	-0.8	-1.2	-0.7	-0.2	0.0	-1.3	-0.7	-0.4	-1.4	-0.8	0.3	-0.7	0.3	-1.1	-0.9	-0.4	-0.6	-1.1	-1.2	-1.0
Leg fat-free mass (left)	0.5	2.6	14.2	1.2	0.9	-0.3	0.4	-0.2	-1.1	2.4	3.8	-0.0	0.4	1.1	-1.6	1.3	1.9	0.8	-3.0	-0.2	-0.5	-0.2	0.6	-3.6	-0.3	1.6
Hayfever, allergic rhinitis or eczema	0.5	1.0	4.5	-1.3	-0.7	-0.8	-0.2	-0.2	-0.6	-2.1	-2.0	-0.2	-1.1	-1.5	0.3	-0.9	-1.7	-0.7	0.7	0.2	0.6	-0.3	-1.0	1.0	-0.1	-0.7
Leg predicted mass (left)	0.5	2.6	14.4	1.3	0.9	-0.3	0.5	-0.2	-1.1	2.4	3.8	0.0	0.5	1.2	-1.6	1.3	2.0	0.9	-3.0	-0.2	-0.5	-0.1	0.7	-3.6	-0.2	1.6
Medication: Ramipril	0.5	0.7	4.5	1.3	0.5	0.5	0.8	0.4	-0.7	0.3	1.0	0.4	1.4	-0.5	-0.3	1.0	0.9	0.4	-2.1	0.5	0.8	-0.7	0.1	-0.9	-0.1	0.6
Medication: Simvastatin	0.5	0.7	2.3	0.2	1.1	0.6	0.7	0.8	0.8	0.5	1.2	1.0	0.3	0.1	1.0	1.1	0.9	1.1	-0.7	1.0	1.5	0.3	0.9	0.2	0.8	1.1
Illnesses of siblings	0.5	0.7	2.1	-0.2	0.6	0.7	1.0	1.2	0.3	-0.1	0.1	1.1	0.2	-0.1	1.0	0.5	-0.4	0.4	1.3	1.2	0.2	1.0	0.0	1.5	1.4	1.0
Father’s age at death	0.5	0.7	1.7	-0.9	-1.0	-1.0	-0.7	0.0	0.6	-0.6	-0.4	-0.7	-1.1	-1.0	-0.1	-1.1	-1.0	-0.9	1.3	-0.6	-0.9	0.2	-1.3	0.5	-0.2	-0.7
Neck or shoulder pain in last month	0.5	0.7	2.2	0.1	0.8	0.7	0.7	1.1	1.4	0.2	-0.2	1.1	-0.1	1.5	1.1	0.8	0.0	0.9	-0.6	1.3	0.6	1.0	1.0	0.3	0.6	0.6
Medication: Ibuprofen	0.5	0.6	2.8	1.0	0.2	-0.1	0.2	0.2	1.2	1.7	1.7	-0.2	0.8	0.6	-0.4	0.1	0.8	0.2	-0.9	-0.9	-1.1	0.5	0.2	-0.5	-0.2	0.0
Whole body fat-free mass	0.5	2.7	20.2	0.5	-0.2	-1.3	-0.6	-1.2	-1.8	1.1	3.1	-1.1	-0.4	0.2	-2.7	0.4	1.2	-0.3	-2.4	-1.3	-1.5	-1.1	-0.4	-4.5	-1.0	0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.0	3.2	-0.8	-1.0	-0.9	-1.0	-1.0	-0.6	-1.8	-0.7	-1.0	-0.8	-1.7	-0.6	-0.8	-0.8	-0.9	1.5	-1.2	-0.9	-1.0	-1.3	-0.5	-0.5	-0.9
Miserableness	0.5	0.9	3.3	-0.9	-0.3	-0.0	-0.8	-1.1	-0.7	1.1	1.6	-0.9	-1.2	0.3	-0.9	-0.5	0.3	-0.0	-0.8	-0.4	-1.2	-0.2	0.4	-1.8	-1.8	-1.0
Fractured/broken bones in last 5 years	0.5	0.7	2.9	0.6	0.7	0.2	0.4	0.3	0.8	1.7	1.2	0.5	0.5	0.8	0.1	0.5	0.8	0.6	-1.7	0.0	-0.3	1.7	0.8	-0.5	0.2	0.6
Pain experienced in last month	0.5	0.9	3.0	-1.2	-0.9	-0.7	-0.7	-1.0	-0.4	-0.2	-1.7	-0.8	-0.6	-1.7	-0.4	-1.1	-0.5	-1.0	1.4	-1.0	-0.6	-0.4	-1.2	0.8	-0.3	-0.9
Alcohol drinker status: Previous	0.5	0.6	1.6	0.1	1.0	0.9	1.0	0.7	1.1	0.6	0.1	1.1	-0.2	0.5	1.0	0.8	-0.1	0.9	-1.3	1.1	0.7	0.7	0.6	0.4	0.8	0.6
Reaction Time	0.4	0.8	3.5	1.1	1.1	0.1	0.9	0.2	-0.4	1.9	0.6	1.0	0.7	1.7	0.2	1.0	0.6	1.1	-0.1	0.6	-0.1	0.9	1.5	0.3	0.6	0.8
Ovarian Cancer	0.4	0.6	1.8	0.2	0.4	0.2	0.4	1.2	0.9	0.0	-1.0	0.9	0.4	-0.2	1.4	0.5	-1.0	0.5	0.9	0.8	0.0	0.0	-0.7	1.4	0.9	0.5
Lupus	0.4	0.6	2.7	-0.5	0.5	1.0	0.7	0.6	0.4	1.0	0.8	0.6	-1.1	0.2	0.5	0.2	0.9	0.6	-0.2	1.0	1.0	1.6	0.3	0.1	0.9	0.9
Hearing difficulty/problems: Yes	0.4	0.6	2.2	1.1	0.7	-0.2	0.5	-0.2	0.9	-0.1	-0.2	0.6	0.8	1.4	-0.2	0.7	0.6	0.5	-1.5	-0.0	0.7	0.7	1.2	0.1	0.6	0.7
Medication: Co-codamol	0.4	0.5	3.3	0.5	0.1	1.0	0.3	0.6	0.5	-0.8	-0.8	0.4	0.4	0.3	1.1	-0.0	-0.5	0.3	1.1	0.6	0.2	0.3	0.5	1.8	0.7	-0.1
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	2.0	-1.4	-0.5	-0.9	-0.4	-0.5	0.4	-0.5	-0.3	-0.5	-1.3	0.1	-0.5	-0.5	-1.1	-0.4	0.3	-0.4	-0.6	-0.6	-0.1	-0.6	-0.6	-0.6
Diverticular disease/diverticulitis (self-reported)	0.4	0.4	4.1	-0.2	0.0	0.1	0.1	0.4	1.1	-2.0	-1.2	0.3	-0.2	-0.2	0.0	0.0	-0.3	-0.3	0.3	0.3	-0.1	-0.7	0.3	1.2	0.6	0.3
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	3.0	-0.3	0.6	0.5	0.5	0.3	0.7	-0.1	-0.1	0.7	-0.8	-0.1	0.9	0.3	0.2	0.5	-0.2	0.6	1.0	1.7	0.6	1.2	0.8	0.4
Allergy	0.4	0.9	4.1	1.2	0.7	1.4	0.1	0.6	0.5	1.8	2.0	0.3	1.3	1.5	0.1	0.7	1.9	0.6	0.2	0.0	-0.3	0.2	0.6	-0.2	0.6	0.9
Pain all over the body in last month	0.4	0.5	2.2	1.5	0.3	-0.1	0.4	0.0	0.5	0.9	-1.1	0.3	1.1	0.2	0.9	0.3	-0.3	0.5	-0.6	-0.0	0.7	0.8	0.5	1.1	0.3	-0.1
Qualifications: A levels/AS levels or equivalent	0.4	0.9	4.2	-1.0	-1.1	-0.4	-0.9	-0.4	-0.1	-1.0	0.1	-1.1	-0.7	-1.5	-0.8	-0.9	-0.4	-1.2	1.2	-0.8	-1.2	-0.2	-2.0	-0.8	-0.1	-0.3
Mouth/teeth dental problems: Dentures	0.4	0.7	6.8	0.3	0.3	0.5	0.4	-0.6	0.6	1.2	1.0	-0.1	0.2	0.8	-0.6	0.2	0.7	0.4	-2.6	0.0	0.1	0.2	0.9	-1.6	-0.8	-0.1
Medication: Lansoprazole	0.4	0.4	1.7	-0.7	-0.3	0.2	-0.6	0.4	1.3	-1.1	-0.2	0.1	-0.6	-0.5	0.3	-0.5	-0.6	-0.4	1.2	0.1	-0.6	-0.2	-0.3	1.3	0.3	-0.4
Exposure to tobacco smoke at home	0.4	0.4	1.7	0.1	-0.4	-1.0	-0.5	-1.2	-0.8	-0.0	-0.3	-0.5	-0.2	-0.8	-0.6	-0.4	-0.5	-0.4	1.0	-1.0	-1.3	0.0	-0.1	-0.3	-0.4	-0.3
Birth weight of first child	0.4	0.8	2.6	-1.4	-0.6	-1.1	-0.4	-0.3	0.1	-1.2	-1.4	-0.3	-1.4	-0.9	0.1	-0.5	-1.4	-0.5	1.6	-0.4	-0.7	-0.3	-1.2	-0.1	0.3	-0.1
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	2.1	-0.7	-0.6	-0.7	-0.5	-0.1	0.4	-1.0	-1.2	-0.2	-0.3	-1.3	-0.1	-0.4	-1.3	-0.7	1.2	0.1	-0.9	-0.1	-1.5	0.2	0.1	-0.1
Blood clot in the leg (DVT)	0.4	0.5	1.8	-0.5	-0.5	-1.3	-0.1	-0.3	-0.5	-1.1	-1.3	-0.3	-0.7	-1.1	-0.2	-0.0	-0.8	-0.1	-1.0	-0.2	0.2	-0.6	-0.8	-0.8	-0.5	-0.4
Medication: Amlodipine	0.4	0.6	3.4	0.4	0.2	0.5	-0.4	-0.7	0.1	1.5	1.3	-0.2	0.5	0.6	-0.5	-0.3	1.6	0.0	-1.9	-0.7	0.1	0.9	0.7	-0.4	-0.5	-0.4
Medication: Ventolin 100micrograms inhaler	0.4	0.5	2.2	-0.9	-0.6	-0.1	-0.7	-0.5	0.4	-0.9	-1.5	-0.6	-0.4	-0.2	-0.3	-0.9	-0.3	-0.8	0.8	-0.8	-0.7	-0.8	0.1	0.6	-0.6	-1.1
Arm fat-free mass (right)	0.4	1.9	13.2	0.6	0.4	-0.7	0.0	-0.6	-1.4	1.6	3.1	-0.4	-0.2	0.5	-1.7	0.8	1.4	0.4	-2.5	-0.5	-0.9	-0.6	0.1	-3.6	-0.5	1.0
Health satisfaction	0.4	0.5	1.1	0.7	0.9	0.2	0.7	0.5	0.9	0.2	0.2	1.0	0.5	0.4	0.9	0.9	0.5	0.9	-0.8	0.6	0.6	0.6	1.0	0.6	0.8	0.7
Arm predicted mass (right)	0.4	1.9	14.4	0.3	0.3	-0.7	-0.2	-0.8	-1.4	1.5	3.1	-0.6	-0.4	0.5	-1.8	0.6	1.4	0.3	-2.3	-0.7	-1.0	-0.6	0.0	-3.8	-0.6	0.9
Age at last live birth	0.4	0.6	1.4	0.2	-1.0	-1.0	-0.7	-0.6	-0.5	-1.0	0.1	-1.2	0.2	-0.6	-0.8	-1.1	-0.2	-0.8	0.8	-1.0	-0.6	-0.9	-1.1	-0.7	-0.9	-0.9
Illnesses of siblings: Diabetes	0.4	0.4	1.2	0.5	0.7	0.6	0.6	0.6	-0.6	-0.4	1.0	0.4	0.3	0.1	0.3	1.1	1.0	0.9	-0.8	0.6	1.0	-0.1	0.5	-0.1	0.5	0.9
Leg fat-free mass (right)	0.4	2.3	13.3	1.0	0.6	-0.6	0.1	-0.4	-1.3	2.1	3.4	-0.3	0.2	1.0	-1.9	0.9	1.7	0.5	-2.9	-0.4	-0.7	-0.2	0.4	-3.6	-0.5	1.2
Handedness (chirality/laterality): Left-handed	0.4	0.5	1.9	-0.2	-0.6	-0.6	-0.8	-0.3	-0.3	-0.7	0.3	-0.6	-0.3	-1.3	-0.9	-0.4	-0.5	-0.9	-0.5	-0.7	-0.5	-1.4	-1.1	-0.7	-0.4	-0.3
Qualifications: nursing, teaching	0.4	0.6	2.9	0.7	-0.0	0.4	0.2	0.6	1.0	-0.6	0.5	0.1	0.5	-1.0	0.6	-0.0	-0.2	-0.1	1.4	-0.2	-0.3	0.7	-1.3	1.7	1.5	0.6
Whole body water mass	0.4	2.5	19.1	0.6	0.0	-1.1	-0.4	-1.0	-1.5	1.3	3.2	-0.9	-0.3	0.3	-2.5	0.5	1.4	-0.1	-2.5	-1.1	-1.3	-1.0	-0.2	-4.4	-0.8	0.9
Leg predicted mass (right)	0.4	2.3	13.3	1.1	0.6	-0.5	0.2	-0.4	-1.2	2.1	3.5	-0.2	0.3	1.0	-1.8	1.0	1.7	0.6	-3.0	-0.4	-0.7	-0.2	0.4	-3.6	-0.4	1.3
Number of self-reported non-cancer illnesses	0.4	0.7	1.7	-0.7	-0.8	-0.6	-1.2	-1.2	0.2	-0.6	-0.6	-1.0	-0.5	-0.5	-0.6	-0.9	-0.1	-0.8	0.3	-1.2	-1.3	-1.1	-0.5	-0.8	-1.3	-1.3
Basal metabolic rate	0.4	2.2	15.4	0.7	0.3	-0.9	-0.1	-0.6	-1.4	1.5	3.3	-0.5	-0.1	0.5	-2.0	0.8	1.4	0.3	-2.6	-0.7	-1.0	-0.7	0.1	-3.9	-0.5	1.1
Arm fat-free mass (left)	0.4	1.9	13.3	0.6	0.3	-0.7	-0.1	-0.6	-1.3	1.5	3.2	-0.5	-0.2	0.5	-1.8	0.7	1.4	0.3	-2.4	-0.7	-0.9	-0.6	0.0	-3.6	-0.5	1.0
Average weekly beer plus cider intake	0.4	0.6	5.7	-0.7	-0.3	-0.7	-0.1	-1.2	-2.4	-0.5	-1.1	-0.3	-0.5	-0.7	-0.0	-0.5	-0.9	-0.0	-0.2	-0.3	-0.0	-0.2	-0.2	-0.8	-0.8	-0.7
Arm predicted mass (left)	0.4	1.9	12.2	0.9	0.6	-0.6	0.1	-0.4	-1.1	1.6	3.2	-0.2	0.1	0.7	-1.5	1.0	1.5	0.6	-2.6	-0.5	-0.7	-0.4	0.3	-3.5	-0.2	1.2
Alzheimer’s Disease (in father)	0.3	0.3	2.5	0.1	0.1	-0.7	0.0	-0.5	-1.6	-0.8	0.6	0.1	-0.4	-0.3	-0.8	0.4	0.3	-0.0	-0.6	0.2	-0.1	0.1	0.7	-1.0	-0.5	0.0
Coronary Artery Disease (CAD)	0.3	0.3	1.0	0.1	-0.8	-0.5	-0.7	-0.5	-0.0	-0.3	-0.3	-0.7	0.4	-1.0	-0.3	-0.8	-0.1	-0.5	-0.4	-0.9	-0.3	-0.6	-0.6	-0.0	-0.7	-0.8
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	1.8	-0.9	-0.3	0.1	-0.3	-0.6	0.1	-0.7	-1.3	-0.1	-1.2	-0.9	0.2	-0.7	-0.8	-0.3	1.1	0.0	-0.2	0.6	-0.3	0.7	-0.2	-0.6
Vitamin and mineral supplements	0.3	0.4	2.8	-0.4	-0.2	-0.4	-0.1	-0.3	-0.3	0.3	-1.7	0.2	-0.3	-0.9	0.7	-0.4	-1.5	-0.1	-0.4	-0.1	0.2	0.2	-0.7	0.8	-0.2	-0.6
Pack years adult smoking proportion	0.3	0.4	2.1	0.1	-0.1	0.4	-0.1	0.4	-1.4	0.0	-1.0	0.3	-0.0	-0.3	0.7	-0.3	-1.5	0.0	-1.4	0.3	0.3	-0.5	-0.0	-0.0	-0.9	-0.9
Qualifications: CSEs or equivalent	0.3	0.4	2.3	-0.6	-0.2	-0.6	-0.3	-0.1	-0.7	-0.3	-0.3	0.1	-0.4	-0.9	0.0	-0.1	-1.5	-0.2	-0.4	0.1	-0.9	-1.0	-0.5	-0.7	-0.5	-0.4
Chronic bronchitis/emphysema (father)	0.3	0.3	2.5	-0.2	0.3	0.3	0.1	-0.5	-0.1	0.0	-1.6	0.4	-0.4	0.4	0.7	0.4	-0.2	0.6	0.6	0.8	1.0	0.6	0.4	-0.0	0.1	0.3
Mouth/teeth dental problems	0.3	0.4	1.6	0.3	-0.4	-0.5	-0.5	0.1	-0.5	-1.0	0.7	-0.4	0.4	-1.1	-0.8	-0.2	0.3	-0.8	1.2	-0.9	-0.6	-1.3	-0.7	-0.1	0.0	-0.2
Number of live births	0.3	0.4	3.6	0.1	-0.0	-0.4	0.2	-0.7	-0.6	-0.7	-1.9	-0.0	0.1	-1.3	0.4	0.2	-0.5	0.0	0.1	-0.6	0.1	-0.6	-0.6	0.0	0.0	-0.1
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	2.0	0.5	-0.1	-0.6	-0.0	0.2	1.0	1.1	1.2	-0.3	0.3	0.1	-0.4	-0.2	-0.1	-0.1	-0.5	-1.0	-1.4	0.1	-0.2	-0.3	-0.2	-0.2
Medication: Seretide 50 evohaler	0.3	0.4	3.2	0.1	-0.3	-0.0	-0.4	-0.5	-0.7	-0.7	0.1	-0.4	0.2	-0.5	-0.8	-0.3	0.4	-0.6	-1.8	-0.3	0.1	0.2	0.2	-1.0	-1.0	-0.8
Mean time to correctly identify matches	0.3	0.7	3.5	1.1	0.9	-0.3	0.6	-0.1	-0.7	1.9	0.7	0.6	0.8	1.7	-0.2	0.9	0.7	0.8	-0.0	0.0	-0.4	0.5	1.1	-0.2	0.3	0.7
Alcohol intake frequency.	0.3	0.7	2.0	-1.3	-0.7	-0.3	-0.6	-0.6	0.2	-1.4	-1.0	-0.5	-1.2	-0.2	-0.4	-0.9	-1.4	-0.6	0.1	-0.1	-0.7	-1.4	-0.1	-0.2	-0.9	-1.1
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.3	2.1	-0.3	-0.0	0.8	0.2	0.7	0.0	-0.3	-0.7	0.5	-0.1	0.3	0.8	-0.3	-0.5	-0.0	0.6	0.8	1.0	0.7	-0.3	1.4	0.4	0.0
Supplements: Vitamin C	0.3	0.3	1.6	-1.3	-0.4	0.0	-0.7	0.3	0.5	-0.8	0.6	-0.4	-0.8	0.2	0.0	-0.4	-0.1	-0.5	0.6	-0.1	-0.5	-1.1	-0.1	-0.6	-0.3	-0.2
Average weekly red wine intake	0.3	0.4	1.9	-0.1	0.6	0.3	0.7	0.7	0.7	1.4	0.9	0.5	-0.2	0.7	0.0	0.6	0.9	0.4	0.5	0.1	0.6	-0.1	0.4	0.9	0.8	0.7
Medication: Blood pressure	0.3	0.6	1.7	0.5	1.0	0.9	0.5	0.7	0.7	0.7	1.3	0.8	0.6	0.3	0.9	0.9	1.1	1.0	-0.9	0.6	0.3	0.3	0.8	0.3	0.6	0.8
Medication: Atorvastatin	0.3	0.4	1.8	0.5	0.7	0.9	0.4	-0.3	0.0	0.5	0.5	0.4	0.3	1.0	0.2	0.4	1.3	0.6	-0.5	0.4	0.1	1.2	1.4	0.0	0.2	0.3
Diastolic blood pressure, automated reading	0.3	0.8	2.7	-0.3	-0.7	-1.2	-1.1	-0.6	-0.4	-0.6	-1.0	-0.6	0.2	-0.7	0.0	-0.9	-1.5	-0.6	-1.0	-1.3	-0.7	-0.9	-0.5	-0.0	-1.3	-1.7
Cholesterol lowering medication	0.3	0.4	1.3	0.1	0.8	0.1	0.8	0.3	0.7	-0.0	0.6	0.7	-0.4	0.3	1.0	0.8	0.2	1.0	0.0	0.5	0.3	0.8	1.1	0.1	0.5	0.6
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	2.1	-0.2	-0.4	-1.4	-0.0	-0.1	-0.3	-1.0	-1.1	-0.2	-0.4	-1.0	-0.2	0.0	-0.9	-0.0	-1.1	-0.2	0.2	-0.6	-0.7	-0.6	-0.3	-0.3
Heart disease (siblings)	0.3	0.4	2.5	-1.2	-0.3	-0.2	-0.6	-1.0	0.0	-0.6	-0.5	-0.6	-1.6	-0.1	-0.5	-0.4	-0.4	-0.2	0.3	-0.2	-0.1	-1.1	0.1	-0.7	-0.6	-0.4
Pack years of smoking	0.3	0.5	2.5	0.0	-0.3	0.0	-0.4	-0.1	-1.6	-0.0	-0.7	-0.1	-0.1	-0.4	0.0	-0.4	-1.2	-0.3	-1.5	-0.1	0.0	-0.8	-0.2	-0.8	-1.2	-1.1
Schizophrenia vs Biploar Disorder	0.2	0.3	1.7	0.3	-0.1	0.0	-0.2	-0.9	-0.7	0.6	0.3	-0.5	0.2	0.5	-0.8	-0.1	1.3	-0.0	-0.4	-0.3	-0.3	0.3	1.0	-0.4	-0.8	-0.4
Alzheimer’s Disease (in mother)	0.2	0.2	0.9	-0.1	0.1	-0.7	0.3	0.0	1.0	0.2	-0.4	0.3	-0.2	-0.9	0.3	0.2	-0.7	0.1	-0.2	-0.1	-0.3	0.6	-0.4	-0.0	0.2	0.3
Alzheimer’s Disease (including proxy)	0.2	0.3	1.9	0.1	-0.1	-1.3	0.0	-0.6	-0.2	-0.6	-0.3	0.0	-0.3	-1.4	-0.5	0.3	-0.7	-0.0	-0.3	-0.1	-0.5	0.4	-0.4	-0.7	-0.1	0.3
Allergy or Eczema	0.2	0.5	2.3	-0.5	0.3	0.2	0.9	0.8	-0.5	-0.8	-1.0	0.8	-0.3	-0.9	1.0	0.3	-0.8	0.4	-0.2	1.2	1.5	0.7	-0.2	0.8	0.6	0.5
Hypothyroidism (self reported)	0.2	0.3	3.7	-0.4	-0.4	0.7	-0.4	-0.5	-1.9	0.6	0.1	-0.5	0.2	-0.1	-0.6	-0.3	0.7	-0.5	0.2	-0.2	-0.5	-0.2	-0.3	-0.7	-0.5	-0.1
Respiratory disease	0.2	0.3	1.3	1.0	0.3	-1.2	0.6	-0.3	1.1	0.1	0.4	0.1	0.7	0.7	-0.2	0.2	-0.3	0.3	-1.0	-0.2	-0.5	0.3	0.9	-0.3	-0.3	-0.3
Relative age of first facial hair	0.2	0.4	1.8	0.2	0.3	0.4	0.4	-0.1	0.2	-0.3	-0.8	0.5	-0.2	-0.4	0.5	0.1	0.3	0.3	0.7	0.8	0.6	1.4	0.4	1.1	0.9	0.6
Trunk fat percentage	0.2	0.8	2.1	0.0	1.3	0.4	1.1	1.1	-0.2	0.9	0.7	1.4	0.4	0.2	1.2	1.2	0.2	1.4	-1.2	1.3	1.1	0.4	0.7	-0.1	0.6	1.1
Fed-up feelings	0.2	0.4	2.4	-0.2	-0.3	-0.5	-0.6	-1.0	0.1	-0.0	0.4	-0.5	-0.6	0.1	-0.9	-0.3	-0.2	-0.2	-0.5	-0.3	-0.8	-1.0	0.3	-1.6	-1.3	-0.7
Supplements: Glucosamine	0.2	0.2	1.3	0.9	0.3	0.8	0.5	0.5	0.4	-0.0	0.8	0.2	1.1	0.6	-0.0	0.4	0.5	0.2	-0.2	0.2	-0.1	-0.1	0.3	-0.1	0.3	0.3
Medication: Levothyroxine sodium	0.2	0.4	2.3	0.2	-0.2	-0.0	-0.3	-1.1	-1.5	0.3	0.4	-0.5	0.3	0.3	-0.9	-0.2	0.9	-0.2	-0.4	-0.3	-0.7	-0.5	-0.0	-1.5	-0.6	0.0
Trunk fat mass	0.2	0.8	2.9	0.1	1.1	-0.1	0.8	0.7	-0.7	1.1	1.6	0.9	0.2	0.3	0.3	1.2	0.6	1.2	-1.7	0.8	0.6	-0.0	0.5	-1.5	0.3	1.3
Had menopause	0.2	0.2	1.3	-0.6	0.1	0.7	-0.2	-0.2	-1.1	1.0	0.1	0.0	-0.8	0.6	-0.0	0.0	0.4	-0.1	-0.1	0.0	-0.4	0.3	0.1	-0.7	-0.4	-0.2
Financial difficulties in last 2 years	0.2	0.3	1.2	0.2	0.5	1.1	0.6	0.5	-0.3	0.2	-0.7	0.7	0.1	0.2	0.7	0.2	0.0	0.5	-0.6	0.8	0.7	0.6	0.4	0.7	0.6	0.3
Asthma	0.2	0.5	2.2	0.9	0.7	0.1	0.9	0.2	0.8	0.5	0.1	0.5	0.8	1.1	0.4	0.7	0.6	0.8	-0.9	0.3	0.5	0.8	1.5	0.3	0.2	0.1
Chronic bronchitis/emphysema (mother)	0.2	0.3	2.9	0.8	0.1	-0.8	0.0	-0.6	-0.6	-0.4	-1.7	0.1	0.8	0.3	0.1	0.5	-0.2	0.2	-0.1	-0.1	0.2	-0.3	0.2	-0.2	-0.0	-0.1
High blood pressure (siblings)	0.2	0.3	1.5	0.6	-0.1	-0.3	-0.4	-0.3	0.5	1.1	0.5	-0.4	0.2	1.0	-0.3	-0.1	0.8	0.2	-1.2	-0.8	-0.3	0.1	0.6	-0.7	-0.6	-0.4
Age at first live birth	0.2	0.4	1.1	-0.1	-0.8	-0.5	-0.7	-0.3	0.0	-0.8	0.7	-0.8	-0.1	-0.1	-0.7	-0.9	0.1	-0.7	1.0	-0.4	-0.5	-0.4	-1.0	-0.9	-0.6	-0.5
Number of full sisters	0.2	0.3	1.6	0.1	0.5	0.3	0.4	-0.3	-0.9	0.6	0.5	0.3	-0.2	-0.2	0.3	0.4	0.6	0.7	-1.2	0.2	1.0	0.3	0.3	-0.7	-0.1	0.2
Commuting to job workplace: Car/motor vehicle	0.2	0.2	1.3	-0.4	0.1	-0.7	-0.1	-0.9	-0.0	-0.4	-0.1	-0.0	-0.5	-0.5	-0.1	-0.0	-0.3	0.1	1.1	-0.2	-0.5	-0.5	-0.2	-0.5	0.1	0.2
Illnesses of father: Heart disease	0.2	0.3	1.8	-1.0	-0.2	0.5	-0.5	0.4	-0.5	0.1	0.2	-0.1	-0.7	-0.4	0.5	-0.5	-0.1	-0.2	1.4	-0.0	-0.3	-0.7	-0.5	0.8	0.0	-0.3
Asthma (self-reported)	0.2	0.3	1.5	0.7	0.5	-0.2	0.7	0.0	1.0	0.4	-0.2	0.3	0.7	1.0	0.3	0.5	0.2	0.6	-0.6	0.1	0.3	0.7	1.2	0.3	0.0	-0.0
Illnesses of father: None of the above (group 1)	0.2	0.2	1.5	0.1	-0.1	-0.2	0.3	0.1	1.1	-1.2	-0.3	-0.0	0.3	-0.4	-0.2	0.3	-0.8	-0.2	-0.3	-0.3	-0.0	-0.4	-0.1	0.1	0.3	0.2
Number of operations (self-reported)	0.2	0.3	1.9	0.2	-0.4	0.1	-0.3	-0.3	0.2	-0.3	-0.8	-0.5	0.1	-0.0	-0.2	-0.4	-0.4	-0.4	1.0	-0.7	-1.4	-0.3	0.0	1.1	0.1	-0.4
Risk taking	0.2	0.3	1.5	-0.3	-0.3	-0.6	-0.0	-0.1	-0.5	-0.7	0.1	-0.5	-0.8	-1.2	-0.1	-0.5	-0.5	-0.1	-0.2	-0.7	0.8	-0.0	-0.0	0.5	-0.1	-0.5
Ever depressed for a whole week	0.2	0.2	1.9	-0.8	0.0	0.1	-0.1	-0.3	0.1	-0.6	-0.6	0.1	-1.4	-0.8	0.3	0.0	-0.7	-0.1	0.0	-0.1	0.1	0.2	-0.5	0.4	0.3	-0.0
Unable to work because of sickness or disability	0.2	0.3	1.8	0.1	-0.3	-0.5	-0.2	-0.6	-0.1	-0.1	-1.4	-0.2	0.2	-0.5	0.4	-0.6	-0.5	-0.2	0.0	-0.7	-0.3	1.1	-0.1	0.4	-0.4	-0.9
Medication: Omeprazole (e.g. Zanprol)	0.2	0.3	2.1	-1.2	-0.1	0.1	-0.4	-0.1	0.1	-0.6	-0.7	-0.1	-1.4	-0.3	0.3	-0.4	-0.4	-0.0	-0.4	-0.3	-0.7	-0.1	0.0	-0.2	-0.3	-0.4
Lung FVC	0.1	0.5	2.3	0.1	0.7	1.2	0.5	-0.2	-0.3	0.7	-0.0	0.2	0.3	0.8	0.4	-0.1	1.4	0.7	-1.5	-0.0	0.4	1.1	1.0	-0.5	0.1	-0.4
Taking other prescription medications	0.1	0.1	0.6	-0.2	0.4	0.4	0.4	0.1	-0.0	-0.8	-0.2	0.5	-0.5	-0.2	0.3	0.4	0.4	0.3	-0.7	0.2	0.2	-0.3	0.5	-0.3	-0.1	0.0
Had other major operations	0.1	0.1	0.4	0.0	0.3	0.5	0.5	0.3	0.5	-0.1	-0.4	0.4	-0.2	0.4	0.6	0.3	-0.1	0.2	0.4	0.1	-0.4	0.0	-0.2	0.7	0.6	0.2
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	2.4	0.0	-0.1	0.2	-0.1	-0.5	-1.6	0.4	0.5	-0.2	0.3	0.3	-0.6	0.1	0.8	-0.1	-0.2	0.0	-0.3	-0.4	0.0	-0.8	-0.3	0.2
Exposure to tobacco smoke outside home	0.1	0.2	0.9	-0.9	0.1	-0.6	-0.2	-0.4	-0.1	0.5	0.6	-0.0	-0.8	-0.2	0.2	-0.1	-0.2	0.2	0.1	-0.3	-0.8	-0.0	0.5	-0.7	-0.4	-0.4
Medication: Omeprazole	0.1	0.1	0.6	-0.2	0.3	0.5	0.2	0.1	0.5	-0.1	-0.4	0.3	-0.6	-0.0	0.4	-0.0	-0.1	0.3	-0.8	-0.0	-0.2	0.2	0.5	0.0	-0.0	-0.0
Heart disease (mother)	0.1	0.2	1.5	-0.5	0.4	0.2	-0.0	-0.3	0.6	0.1	0.1	0.2	-0.5	1.2	-0.0	0.1	0.4	0.2	0.5	-0.0	-0.2	-0.1	0.6	0.3	0.3	0.3
Overall health rating	0.1	0.2	2.5	-0.1	0.0	0.2	-0.3	-0.1	0.4	-1.6	-0.9	0.2	-0.0	-0.3	0.2	0.0	-0.8	-0.0	-0.5	0.2	0.1	-0.8	0.4	0.0	-0.3	-0.3
Medication: Aspirin	0.1	0.2	0.6	0.3	0.5	0.4	0.2	0.3	0.6	0.7	0.7	0.3	-0.1	0.2	0.6	0.3	0.5	0.5	-0.4	0.2	0.5	0.0	0.8	0.3	-0.0	0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.2	0.6	-0.1	0.3	0.7	0.1	0.5	0.5	0.1	-0.1	0.5	0.0	0.4	0.4	0.2	0.1	0.2	-0.2	0.8	-0.2	0.8	0.1	0.6	0.4	0.5
Breast cancer (self-reported)	0.1	0.2	1.3	-0.2	-0.0	0.4	-0.1	0.4	1.1	-0.5	-0.3	0.4	-0.1	0.1	0.4	-0.2	-0.1	-0.3	0.6	0.3	0.2	0.3	-0.1	0.8	0.5	0.1
Osteoporosis (self-reported)	0.1	0.2	0.7	-0.2	-0.3	0.3	-0.4	-0.2	0.8	-0.5	-0.7	-0.2	-0.1	-0.8	0.0	-0.5	-0.0	-0.5	0.2	-0.2	-0.1	-0.1	-0.4	0.6	0.1	-0.4
Medication: Aspirin	0.1	0.2	0.7	0.1	0.3	0.5	-0.0	0.3	0.5	0.8	0.7	0.2	-0.2	0.2	0.5	0.2	0.6	0.4	-0.4	0.2	0.6	-0.1	0.7	0.2	-0.2	0.0
Commuting to job workplace: Public transport	0.1	0.2	1.2	0.3	0.0	0.2	0.1	0.7	1.1	-0.1	-0.1	0.1	0.3	0.3	0.3	0.2	-0.1	0.1	0.5	0.1	-0.3	-0.2	0.1	0.8	0.6	0.3
Supplements: Calcium	0.1	0.1	0.8	-0.5	-0.1	-0.0	-0.1	0.1	-0.1	-0.5	-0.1	-0.0	-0.7	-0.5	-0.3	0.3	0.2	-0.1	0.0	0.1	-0.2	-0.9	-0.2	-0.5	0.4	0.5
Hair Pigment	0.0	1.1	5.6	0.6	1.2	0.3	1.3	0.4	-0.3	2.1	0.2	1.1	0.4	0.8	1.2	0.8	0.6	1.3	-1.8	0.6	0.7	2.4	1.2	0.2	0.4	0.6

Hub : Genes

ITIH4-AS1

Models

Trait associations