Best TWAS P=3.17e-08 · Best GWAS P=6.24e-12 conditioned to 1.88e-10
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | CYBRD1 | 0.33 | 0.18 | lasso | 7 | 0.27 | 5.2e-33 | 3.7 | 5.2 | 2.6e-07 | 0.13 | 0.65 | 0.30 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | CYBRD1 | 0.37 | 0.16 | lasso | 9 | 0.30 | 3.0e-39 | -4.5 | 5.5 | 3.2e-08 | 0.10 | 0.04 | 0.96 | TRUE |
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | CYBRD1 | 0.08 | 0.07 | enet | 11 | 0.07 | 3.3e-08 | 5.5 | -5.5 | 3.6e-08 | -0.12 | 0.00 | 1.00 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CYBRD1 | 0.08 | 0.06 | blup | 68 | 0.08 | 1.5e-08 | -4.5 | 5.4 | 6.2e-08 | 0.16 | 0.03 | 0.97 | FALSE |