Best TWAS P=1.03e-13 · Best GWAS P=2.87e-14 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | ZBTB38 | 0.08 | 0.04 | lasso | 4 | 0.03 | 8.1e-04 | -7.5 | -7.4 | 1.0e-13 | 0.95 | 0.01 | 0.99 | TRUE |
| 2 | GTEx | Testis | ZBTB38 | 0.14 | 0.06 | lasso | 8 | 0.05 | 2.8e-03 | -6.2 | -6.7 | 2.9e-11 | 0.60 | 0.17 | 0.73 | FALSE |
| 3 | GTEx | Thyroid | ZBTB38 | 0.11 | 0.03 | enet | 32 | 0.04 | 2.9e-04 | -5.6 | -5.4 | 7.1e-08 | 0.64 | 0.06 | 0.94 | FALSE |
| 4 | NTR | Blood | ZBTB38 | 0.03 | 0.01 | lasso | 3 | 0.01 | 2.2e-05 | -7.4 | -7.1 | 1.1e-12 | 0.84 | 0.01 | 0.99 | FALSE |
| 5 | The Cancer Genome Atlas | Soft Tissue Sarcoma | ZBTB38 | 0.04 | 0.03 | lasso | 3 | 0.04 | 3.0e-03 | -5.2 | -6.5 | 1.1e-10 | 0.60 | 0.05 | 0.35 | FALSE |