[Hub]/) : Traits : Breast Cancer :

chr3:98,838,914-100,872,536

Best TWAS P=1.8e-10 · Best GWAS P=5.17e-10 conditioned to 0.115

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Coronary LNP1 0.15 0.00 lasso 3 -0.01 5.7e-01 2.4 -5.5 4.5e-08 0.72 0.04 0.41 FALSE
2 GTEx Cells Transformed fibroblasts FILIP1L 0.15 0.21 enet 19 0.20 5.5e-15 -5.3 5.5 5.2e-08 -0.68 0.78 0.22 FALSE
3 GTEx Cells Transformed fibroblasts CMSS1 0.08 0.02 enet 17 0.05 1.5e-04 5.4 -5.2 1.9e-07 0.48 0.54 0.28 FALSE
4 GTEx Esophagus Mucosa CMSS1 0.06 0.08 lasso 4 0.08 4.2e-06 5.6 -5.8 5.7e-09 0.49 0.42 0.48 FALSE
5 GTEx Esophagus Muscularis NIT2 0.12 0.01 enet 12 0.03 9.7e-03 -2.2 -5.2 2.0e-07 0.61 0.13 0.64 FALSE
6 GTEx Spleen NIT2 0.26 0.00 enet 41 0.10 2.0e-03 -2.8 -6.0 2.6e-09 0.68 0.08 0.62 FALSE
7 GTEx Stomach TBC1D23 0.08 0.02 lasso 3 0.02 3.5e-02 -4.7 -5.3 1.2e-07 0.59 0.10 0.39 FALSE
8 The Cancer Genome Atlas Breast Invasive Carcinoma C3orf26 0.03 0.02 blup 163 0.02 5.8e-06 5.4 -6.1 1.2e-09 0.65 0.50 0.47 FALSE
9 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma C3orf26 0.02 0.01 blup 163 0.01 3.4e-02 -5.2 -6.1 1.1e-09 0.83 0.09 0.60 FALSE
10 The Cancer Genome Atlas Brain Lower Grade Glioma COL8A1 0.03 0.03 enet 6 0.01 9.2e-03 -5.8 5.3 1.3e-07 -0.87 0.01 0.96 FALSE
11 The Cancer Genome Atlas Lung Adenocarcinoma C3orf26 0.05 0.01 blup 163 0.03 2.2e-04 5.4 -6.4 1.8e-10 0.84 0.06 0.87 TRUE
12 The Cancer Genome Atlas Pancreatic Adenocarcinoma C3orf26 0.10 0.02 blup 163 0.05 4.6e-03 -4.9 -6.2 6.5e-10 0.78 0.07 0.66 FALSE
13 The Cancer Genome Atlas Prostate Adenocarcinoma C3orf26 0.03 0.01 blup 163 0.02 2.2e-03 -4.3 -5.5 4.9e-08 0.69 0.22 0.25 FALSE