Best TWAS P=5.38e-09 · Best GWAS P=3.05e-09 conditioned to 0.113
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue | RP11-250B2.5 | 0.13 | 0.11 | enet | 16 | 0.08 | 5.1e-05 | 4.8 | 5.3 | 1.2e-07 | 0.74 | 0.04 | 0.93 | FALSE |
| 2 | METSIM | Adipose | RP11-250B2.5 | 0.03 | 0.03 | lasso | 4 | 0.01 | 3.5e-03 | 5.8 | 5.8 | 5.4e-09 | 0.89 | 0.01 | 0.97 | TRUE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | RP11-250B2.5 | 0.09 | 0.06 | lasso | 7 | 0.08 | 4.6e-11 | 4.2 | 5.6 | 2.6e-08 | 0.86 | 0.01 | 0.99 | FALSE |