Best TWAS P=1.68e-10 · Best GWAS P=3.05e-24 conditioned to 3.9e-15
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | CRISPLD1 | 0.04 | 0.01 | lasso | 4 | 0.02 | 0.00161 | 4.1 | 5.5 | 4.1e-08 | -0.06 | 0.22 | 0.02 | TRUE |
| 2 | The Cancer Genome Atlas | Esophageal Carcinoma | HNF4G | 0.15 | 0.04 | enet | 13 | 0.10 | 0.00043 | -7.4 | -6.4 | 1.7e-10 | 0.43 | 0.04 | 0.17 | TRUE |