[Hub]/) : Traits : Breast Cancer :

chr7:143,425,361-144,768,633

Best TWAS P=4.84e-12 · Best GWAS P=1.2e-11 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Caudate basal ganglia ARHGEF5 0.33 0.23 lasso 4 0.21 1.1e-06 6.8 6.9 4.8e-12 0.98 0.00 1.00 TRUE
2 GTEx Brain Cortex ARHGEF5 0.27 0.00 lasso 7 0.03 4.4e-02 -2.0 5.7 1.5e-08 0.73 0.02 0.71 FALSE
3 The Cancer Genome Atlas Brain Lower Grade Glioma ARHGEF5 0.14 0.08 lasso 1 0.08 4.3e-09 6.8 6.8 1.2e-11 1.00 0.00 1.00 FALSE
4 The Cancer Genome Atlas Prostate Adenocarcinoma ARHGEF5 0.10 0.07 enet 17 0.07 4.2e-08 6.8 5.3 1.0e-07 0.88 0.00 1.00 FALSE