Best TWAS P=7.14e-12 · Best GWAS P=0 conditioned to 3.26e-294
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | ATE1 | 0.19 | 0.02 | enet | 26 | 0.09 | 2.3e-07 | 1.51 | 6.9 | 7.1e-12 | -0.16 | 0.57 | 0.02 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | RP11-500G22.2 | 0.55 | 0.31 | enet | 46 | 0.55 | 1.9e-85 | 0.65 | -5.4 | 5.1e-08 | 0.17 | 1.00 | 0.00 | TRUE |
| 3 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | ATE1 | 0.24 | -0.01 | blup | 126 | 0.03 | 5.0e-02 | -1.41 | 5.3 | 1.1e-07 | -0.18 | 0.02 | 0.04 | TRUE |