Best TWAS P=2.18e-08 · Best GWAS P=2.52e-07 conditioned to 0.737
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellum | PPP2R1B | 0.14 | 0.14 | lasso | 4 | 0.12 | 1.6e-04 | -4.9 | -5.2 | 1.9e-07 | 0.86 | 0.03 | 0.83 | FALSE |
| 2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | PPP2R1B | 0.09 | 0.07 | blup | 12 | 0.07 | 3.3e-08 | -5.2 | -5.6 | 2.2e-08 | 0.94 | 0.00 | 1.00 | TRUE |