TWAS hub - PPP2R1B

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1390	0.0300	0.0e+00	0.181	0.178	0.192	0.180	0.183	1.5e-21	4.2e-21	8.3e-23	1.9e-21	1.0e-21
2	GTEx	Adipose Subcutaneous	0.1060	0.0380	1.6e-05	0.046	NA	0.080	NA	0.076	1.1e-04	NA	4.4e-07	NA	8.7e-07
3	GTEx	Adipose Visceral Omentum	0.0730	0.0320	2.6e-03	-0.001	NA	0.002	NA	0.003	3.5e-01	NA	2.5e-01	NA	2.2e-01
4	GTEx	Artery Tibial	0.1449	0.0482	3.3e-06	0.097	NA	0.104	NA	0.111	4.9e-08	NA	1.5e-08	NA	4.9e-09
5	GTEx	Brain Caudate basal ganglia	0.2730	0.1180	8.5e-04	0.144	NA	0.106	NA	0.149	6.3e-05	NA	6.0e-04	NA	4.8e-05
6	GTEx	Brain Cerebellum	0.1380	0.0640	9.0e-03	0.135	NA	0.116	NA	0.125	8.6e-05	NA	2.7e-04	NA	1.6e-04
7	GTEx	Brain Cortex	0.1590	0.0670	2.9e-03	0.073	NA	0.049	NA	0.090	4.6e-03	NA	1.7e-02	NA	1.8e-03
8	GTEx	Brain Frontal Cortex BA9	0.2669	0.1130	5.9e-03	0.071	NA	0.025	NA	0.057	6.3e-03	NA	7.3e-02	NA	1.3e-02
9	GTEx	Brain Nucleus accumbens basal ganglia	0.3580	0.1090	1.3e-04	0.198	NA	0.138	NA	0.171	5.2e-06	NA	1.6e-04	NA	2.6e-05
10	GTEx	Brain Putamen basal ganglia	0.2630	0.0990	9.4e-04	0.181	NA	0.091	NA	0.139	4.4e-05	NA	3.7e-03	NA	3.5e-04
11	GTEx	Cells Transformed fibroblasts	0.1050	0.0320	5.6e-07	0.071	NA	0.116	NA	0.115	4.9e-06	NA	5.5e-09	NA	5.9e-09
12	GTEx	Esophagus Mucosa	0.0880	0.0390	1.9e-03	0.088	NA	0.019	NA	0.073	1.8e-06	NA	2.0e-02	NA	1.4e-05
13	GTEx	Esophagus Muscularis	0.1510	0.0550	5.2e-05	0.042	NA	0.036	NA	0.035	1.4e-03	NA	2.9e-03	NA	3.4e-03
14	GTEx	Lung	0.1194	0.0412	1.3e-05	0.101	NA	0.096	NA	0.099	3.6e-08	NA	9.1e-08	NA	5.6e-08
15	GTEx	Nerve Tibial	0.1985	0.0895	8.1e-04	0.002	NA	0.026	NA	0.022	2.2e-01	NA	5.9e-03	NA	1.0e-02
16	GTEx	Ovary	0.3990	0.1050	1.1e-04	-0.011	NA	0.105	NA	0.015	7.9e-01	NA	1.5e-03	NA	1.3e-01
17	GTEx	Prostate	0.1760	0.0730	6.4e-03	0.101	NA	0.011	NA	0.024	1.7e-03	NA	1.7e-01	NA	8.2e-02
18	GTEx	Testis	0.3420	0.0640	1.2e-13	0.211	NA	0.296	NA	0.355	9.4e-10	NA	1.3e-13	NA	1.5e-16
19	GTEx	Thyroid	0.3190	0.0640	0.0e+00	0.255	NA	0.238	NA	0.264	1.5e-19	NA	3.6e-18	NA	2.5e-20
20	METSIM	Adipose	0.2006	0.0455	5.6e-17	0.101	0.122	0.155	0.139	0.142	7.8e-15	9.3e-18	1.9e-22	3.5e-20	1.2e-20
21	NTR	Blood	0.0194	0.0080	2.1e-04	0.014	0.013	0.013	0.013	0.009	1.5e-05	3.6e-05	4.5e-05	3.2e-05	3.6e-04
22	ROSMAP	Brain Pre-frontal Cortex	0.3234	0.0443	0.0e+00	0.305	0.333	0.358	0.354	0.361	9.5e-40	3.9e-44	4.6e-48	2.0e-47	1.8e-48
23	TCGA	Brain Lower Grade Glioma	0.0892	0.0483	2.5e-07	0.071	0.068	0.067	NA	0.067	1.8e-08	3.3e-08	4.9e-08	NA	4.6e-08
24	TCGA	Soft Tissue Sarcoma	0.1560	0.0930	1.1e-03	0.059	0.058	0.031	NA	0.046	2.1e-04	2.4e-04	5.6e-03	NA	9.5e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24
Waist Hip Ratio (WHR)	16.2	72.9	118.8	9.5	9.6	10.8	8.6	10.3	6.4	8.4	8.8	8.4	8.3	10.9	8.2	6.8	8.0	6.9	4.5	9.7	1.6	10.4	8.3	9.6	10.0	6.1	8.6
Ever had stillbirth, spontaneous miscarriage or termination	8.8	9.4	12.3	3.2	2.6	2.9	2.9	3.3	3.1	3.1	3.3	3.3	3.4	3.2	3.4	2.6	3.3	3.0	0.9	3.5	2.2	3.4	3.4	3.4	2.9	2.5	3.3
Breast Cancer	8.4	20.3	31.4	-4.7	-3.0	-3.6	-4.8	-4.3	-5.2	-4.8	-5.0	-5.0	-5.0	-3.4	-4.9	-3.8	-4.6	-4.9	-3.9	-4.6	-4.9	-4.6	-3.9	-3.0	-4.7	-5.6	-4.8
Lung cancer (father)	6.7	7.8	10.8	3.2	2.5	2.2	2.8	2.9	2.8	2.6	3.0	3.3	3.1	2.2	3.0	1.9	2.9	2.7	2.4	2.9	3.1	3.1	2.4	2.2	3.0	3.1	3.2
Fractured/broken bones in last 5 years	6.5	8.4	13.2	2.9	3.0	3.3	2.9	2.7	2.6	3.1	2.9	3.2	2.8	2.4	2.6	2.2	2.7	3.4	3.6	2.6	2.4	3.2	2.2	3.1	3.0	2.8	3.1
Alzheimer’s Disease (including proxy)	5.8	8.5	13.2	3.5	2.3	2.9	3.2	3.3	2.5	2.8	3.1	3.1	3.2	2.8	3.0	2.5	2.9	2.7	1.4	3.2	1.9	3.4	2.0	3.6	3.2	2.8	3.1
Heart disease (mother)	4.2	5.1	7.2	-2.3	-1.8	-2.4	-2.4	-2.0	-2.6	-2.6	-2.5	-2.5	-2.4	-1.4	-2.3	-1.2	-2.3	-2.0	-2.1	-2.3	-2.3	-2.3	-2.2	-2.0	-2.5	-2.7	-2.5
Medication: Bendroflumethiazide	4.2	6.4	16.1	-2.6	-1.9	-1.7	-3.2	-1.5	-2.8	-2.4	-3.0	-2.4	-2.5	-0.9	-2.5	-2.6	-2.7	-2.6	-2.1	-2.1	-4.0	-2.3	-1.6	-2.0	-2.8	-3.3	-3.3
Hypothyroidism/myxoedema (self-reported)	4.1	8.0	18.7	-2.8	-2.5	-2.7	-2.9	-2.3	-2.4	-2.7	-2.6	-2.7	-2.5	-2.7	-2.3	-2.5	-2.6	-3.7	-4.3	-2.3	-2.2	-2.9	-3.8	-2.5	-3.0	-3.0	-3.0
Lupus	3.8	5.7	13.0	-2.4	-1.4	-1.2	-2.6	-2.5	-2.9	-2.5	-2.8	-3.2	-2.9	-1.6	-2.6	-1.1	-2.5	-1.6	-1.4	-2.2	-3.4	-2.3	-0.7	-1.3	-2.6	-3.6	-2.7
Supplements: Glucosamine	3.8	4.9	7.9	2.2	2.1	2.0	2.5	2.3	2.4	2.3	2.5	2.2	2.3	1.9	2.3	2.1	2.4	2.4	0.6	2.2	1.9	2.3	1.2	2.8	2.3	2.7	2.3
Ulcerative Colitis (UC)	3.6	6.7	12.5	-2.2	-2.2	-2.1	-3.5	-2.1	-3.1	-3.0	-3.1	-3.0	-2.8	-1.2	-2.7	-2.2	-2.8	-2.4	-1.3	-2.3	-3.3	-2.7	-0.8	-1.8	-2.8	-3.0	-3.4
Hypothyroidism (self reported)	3.6	8.2	16.1	-2.6	-2.8	-2.7	-2.8	-2.7	-2.7	-2.9	-2.6	-2.9	-2.7	-3.1	-2.5	-2.0	-2.9	-3.5	-3.9	-2.6	-2.1	-3.0	-4.0	-2.5	-2.8	-2.6	-3.1
Pulse rate, automated reading	3.6	11.7	23.1	3.6	2.5	2.6	3.6	2.8	3.7	3.6	3.4	3.9	3.6	1.1	3.3	2.8	3.4	4.8	2.9	3.0	4.7	3.2	2.4	4.5	3.0	3.8	3.8
Tinnitus: Yes, but not now, but have in the past	3.3	3.6	6.8	-2.1	-2.6	-2.3	-2.2	-1.9	-1.2	-1.9	-1.8	-1.4	-1.7	-2.3	-1.5	-2.2	-1.9	-1.8	-1.8	-1.7	-0.8	-2.2	-1.6	-1.1	-2.4	-2.1	-1.9
Leg pain on walking	3.3	4.1	9.5	2.0	3.1	1.7	2.5	2.0	1.8	1.9	2.2	1.6	1.8	2.3	1.7	1.4	2.9	2.0	2.5	1.8	0.7	2.1	1.8	1.5	2.2	1.5	2.4
Alzheimer’s Disease (in mother)	3.2	3.8	7.4	2.3	2.0	1.9	2.4	2.3	1.2	1.8	2.1	1.9	2.0	2.3	1.8	1.7	1.8	1.7	0.3	2.1	0.9	2.5	1.2	2.7	2.3	1.7	2.2
Number of children fathered	3.1	3.6	9.1	1.3	2.8	2.4	2.2	1.6	1.8	2.1	1.9	1.2	1.5	1.5	1.6	3.0	1.8	2.0	0.7	1.7	1.0	2.0	2.7	0.9	1.8	1.1	2.3
Unable to work because of sickness or disability	2.9	3.7	5.8	1.8	2.4	1.6	2.2	1.5	2.3	2.1	2.1	1.9	1.9	1.6	2.1	2.0	2.4	1.8	2.3	1.9	1.8	1.9	1.6	1.7	1.6	1.6	1.9
Medication: Blood pressure	2.8	4.9	21.9	-2.0	-0.3	-0.1	-3.0	-0.8	-2.6	-1.8	-2.4	-2.0	-2.0	0.5	-1.7	-1.6	-1.8	-3.4	-1.7	-1.1	-4.7	-1.4	-0.7	-1.6	-2.2	-4.0	-2.7
Forced expiratory volume in 1-second (FEV1), predicted	2.8	5.9	14.9	2.1	2.5	2.0	2.7	2.1	2.6	2.8	2.7	2.4	2.4	1.9	2.3	2.5	2.8	2.8	3.9	2.1	2.2	2.3	2.4	1.1	2.0	1.7	2.5
Ever had bowel cancer screening	2.8	3.2	10.7	-1.9	-1.3	-0.9	-2.6	-0.4	-1.9	-1.9	-1.9	-1.4	-1.4	0.3	-1.2	-1.9	-1.0	-2.8	-2.2	-0.7	-3.3	-1.3	-0.0	-1.1	-1.8	-3.2	-2.0
Miserableness	2.8	4.8	7.7	-2.2	-1.6	-2.8	-2.0	-2.5	-1.8	-2.3	-2.2	-2.5	-2.5	-2.5	-2.3	-2.5	-1.8	-1.6	-1.2	-2.5	-1.6	-2.6	-1.0	-2.1	-2.8	-2.6	-2.1
High blood pressure	2.7	7.6	30.7	-2.5	-0.3	-0.6	-3.1	-1.4	-3.3	-2.3	-3.0	-2.9	-3.0	-0.1	-2.7	-2.9	-2.7	-4.0	-0.6	-2.1	-5.5	-2.4	-0.8	-2.5	-2.4	-4.0	-3.6
Medication: Seretide 50 evohaler	2.7	3.1	6.7	-2.0	-1.5	-1.8	-1.2	-2.6	-1.6	-1.5	-1.5	-1.9	-1.7	-2.4	-1.8	-1.8	-1.8	-1.5	-1.5	-2.1	-0.1	-2.1	-2.6	-1.6	-1.4	-0.5	-1.7
Loud music exposure frequency	2.6	2.8	6.5	1.7	2.2	2.6	2.0	1.4	0.9	1.8	1.7	1.3	1.3	1.3	1.3	1.8	1.4	2.3	1.3	1.5	0.6	2.0	1.3	2.0	2.1	1.1	1.9
HDL Cholesterol	2.5	4.1	8.0	-2.3	-2.8	-2.3	-2.0	-2.4	-1.5	-1.9	-2.1	0.0	-1.8	-2.8	-1.9	-2.1	-2.4	-2.2	-1.4	-2.2	-0.1	-2.5	-1.7	-2.1	-2.0	-0.5	-2.4
Waist circumference	2.5	9.2	21.3	3.0	3.2	3.6	3.2	3.8	2.7	3.0	3.2	3.1	2.8	3.2	3.0	2.2	2.3	3.6	2.2	3.4	0.2	3.6	4.6	3.1	3.1	1.0	2.9
Hypertension (Self-reported)	2.5	6.8	31.6	-2.1	-0.2	-0.3	-2.9	-1.1	-3.2	-2.1	-2.7	-2.6	-2.7	0.3	-2.5	-3.0	-2.5	-3.9	-0.9	-1.8	-5.6	-2.1	-0.7	-2.6	-2.0	-3.8	-3.3
Illnesses of mother	2.4	3.0	6.9	2.0	2.2	2.6	2.2	1.2	1.4	2.1	1.9	1.1	1.4	1.2	1.1	1.6	1.0	1.0	2.4	1.2	1.1	1.8	1.7	1.5	2.3	1.9	2.0
Chronic bronchitis/emphysema (father)	2.3	2.7	4.2	1.3	2.0	1.9	2.0	1.0	1.7	1.9	2.0	2.0	1.7	1.0	1.7	1.1	1.7	1.2	0.9	1.6	1.6	1.7	1.6	1.9	1.7	1.6	1.7
Health satisfaction	2.3	3.0	9.4	1.5	1.6	1.4	1.8	1.8	2.1	2.0	1.9	1.7	1.7	1.2	1.8	1.5	1.9	3.1	0.9	1.7	1.3	1.7	2.1	1.7	1.2	0.8	1.7
Blood Red Count	2.2	21.6	36.1	5.1	6.0	5.6	4.1	4.9	4.2	5.2	4.4	5.0	4.7	4.8	4.6	4.8	5.4	4.0	6.0	4.8	3.0	4.9	1.5	3.1	4.9	3.8	4.1
Hayfever, allergic rhinitis or eczema	2.2	4.7	27.4	1.7	-0.4	0.0	1.9	0.5	2.7	1.8	1.8	1.9	2.1	-0.8	1.8	1.4	1.2	3.5	3.1	1.0	5.2	1.1	0.7	2.0	1.3	3.9	2.0
Number of operations (self-reported)	2.2	3.3	6.4	2.2	1.9	1.8	1.9	1.7	1.8	2.0	1.8	1.7	1.8	1.5	1.6	2.5	2.1	0.7	0.4	1.7	1.6	1.8	1.5	2.5	1.9	2.0	1.9
Irritable Bowel Disease (IBD)	2.1	5.0	11.4	-2.0	-2.6	-2.3	-3.4	-1.5	-2.0	-2.5	-2.5	-2.0	-1.9	-1.4	-1.8	-2.3	-2.2	-2.5	-2.1	-1.6	-1.9	-2.4	-0.8	-1.9	-2.9	-2.7	-3.0
Diabetes diagnosed by doctor	2.1	3.4	11.9	-1.8	-1.8	-1.6	-2.3	-0.9	-1.7	-1.9	-2.0	-1.4	-1.6	-1.1	-1.5	-2.2	-1.9	-1.5	-3.5	-1.2	-2.4	-1.7	-0.4	-0.5	-2.0	-2.2	-2.4
Mouth/teeth dental problems: Mouth ulcers	2.1	3.3	5.2	-1.9	-0.9	-1.5	-1.6	-2.3	-2.1	-2.0	-2.0	-1.9	-2.1	-1.5	-2.0	-0.7	-1.7	-1.7	-1.5	-2.1	-1.6	-1.9	-1.9	-1.8	-1.9	-2.2	-1.9
Tinnitus: Yes, now most or all of the time	2.1	2.5	7.2	1.1	1.8	1.9	1.5	1.3	1.7	1.8	1.5	1.8	1.6	1.4	1.7	2.0	2.7	1.9	0.7	1.5	1.6	1.6	0.1	0.2	1.4	0.7	2.0
Number of live births	2.0	2.9	7.0	-1.9	-1.3	-1.9	-0.7	-1.8	-1.3	-1.4	-1.2	-1.5	-1.6	-2.6	-1.7	-1.2	-1.5	-1.8	-2.6	-2.0	-0.4	-1.8	-2.1	-2.1	-1.6	-1.1	-1.7
Vascular/heart problems diagnosed by doctor	2.0	5.4	28.1	1.9	0.1	0.1	2.6	0.8	2.8	1.7	2.4	2.3	2.3	-0.4	2.0	2.1	2.3	3.5	0.9	1.4	5.3	1.6	0.4	2.0	2.0	3.8	3.0
HbA1C	1.9	2.1	5.7	-2.1	-2.1	-1.0	-2.2	-0.5	-0.7	-1.4	-1.5	-0.9	-0.9	-0.8	-0.6	-2.0	-1.2	-1.1	-1.8	-0.5	-1.7	-1.3	0.8	0.6	-2.1	-2.4	-1.4
Financial difficulties in last 2 years	1.9	2.5	8.5	1.1	0.9	0.5	2.1	0.9	2.1	1.6	2.0	1.9	1.5	0.4	1.6	1.5	1.8	2.9	1.1	1.2	2.1	1.2	1.8	1.0	1.1	1.9	1.6
Risk taking	1.9	2.8	5.6	1.6	1.5	1.9	1.6	1.8	1.5	1.5	1.8	1.8	1.7	2.4	1.8	1.2	2.1	2.1	0.9	2.0	0.3	1.9	1.4	1.6	1.7	1.2	1.3
Supplements: Calcium	1.9	2.1	3.7	1.6	1.3	1.3	0.6	1.5	1.7	1.4	1.2	1.8	1.8	1.7	1.8	1.2	1.9	1.2	0.9	1.8	1.2	1.4	1.1	1.9	0.9	0.6	1.5
Relative age of first facial hair	1.8	3.6	7.6	1.8	2.0	1.8	1.2	2.8	1.8	1.8	1.7	2.2	2.2	2.6	2.0	1.7	2.4	1.7	1.2	2.3	0.9	2.1	1.3	2.1	1.7	1.5	1.8
Diabetes (father)	1.8	2.3	6.5	-1.4	-2.5	-1.9	-1.7	-1.2	-1.1	-1.7	-1.6	-1.3	-1.3	-1.5	-1.5	-1.8	-1.9	-1.6	-1.3	-1.5	-0.7	-1.5	-0.9	-0.7	-1.6	-1.3	-1.2
Maternal smoking around birth	1.8	2.6	5.0	1.1	2.0	1.4	2.2	1.4	1.7	1.7	2.1	1.5	1.7	1.1	1.7	1.1	2.0	0.4	1.6	1.6	1.7	1.6	1.8	0.5	1.9	1.4	1.9
Allergy	1.8	4.2	33.2	-1.2	1.4	0.8	-1.4	0.4	-2.4	-1.4	-1.4	-1.6	-1.8	1.9	-1.4	-0.9	-0.5	-3.6	-2.5	-0.5	-5.8	-0.5	0.5	-1.7	-0.8	-3.5	-1.8
Seen a psychiatrist for nerves, anxiety, tension or depression	1.8	2.3	4.6	1.4	1.0	1.5	2.1	1.2	1.7	1.7	1.9	1.8	1.6	0.8	1.7	1.2	1.7	1.9	0.9	1.4	1.5	1.4	1.4	1.1	1.5	1.6	1.6
Suffer from ‘nerves’	1.8	2.8	8.6	-1.6	-2.6	-2.9	-1.8	-2.2	-0.0	-1.4	-1.4	-1.4	-1.0	-2.9	-1.0	-2.2	-1.6	-0.1	-0.2	-1.7	1.5	-1.8	-1.6	-0.3	-2.2	-0.4	-1.3
Medication: Gliclazide	1.8	2.0	3.9	-1.3	-1.7	-1.6	-1.8	-1.0	-1.6	-1.9	-1.7	-1.3	-1.2	-0.0	-1.4	-1.5	-1.2	-1.2	-1.4	-1.1	-2.0	-1.3	-0.4	-1.2	-1.4	-1.3	-2.0
Medication: Blood pressure	1.8	3.4	17.9	-1.4	0.3	0.1	-1.5	-0.7	-2.8	-1.6	-1.9	-1.8	-2.1	0.3	-2.1	-1.9	-2.0	-2.7	-1.2	-1.5	-4.2	-1.2	-0.6	-1.2	-0.8	-2.2	-2.3
Neuroticism	1.7	4.0	6.9	-1.9	-1.4	-2.2	-1.9	-2.6	-1.8	-2.0	-2.1	-2.5	-2.3	-2.2	-2.2	-2.2	-1.9	-1.6	-0.3	-2.4	-1.6	-2.4	-1.3	-1.5	-2.2	-2.0	-2.3
Multivitamins +/- minerals	1.7	2.2	6.1	1.4	0.7	1.1	1.3	1.0	1.5	1.5	1.5	1.5	1.6	0.5	1.4	1.9	1.2	1.8	0.7	1.2	2.5	1.3	1.1	2.3	1.6	1.8	1.7
Pulse rate	1.7	2.8	8.2	1.6	0.9	0.8	1.4	1.4	2.5	1.9	1.7	2.3	2.1	0.2	2.1	0.7	2.0	1.6	0.8	1.7	2.9	1.4	-0.2	2.2	1.1	1.9	1.6
Wheeze or whistling in the chest in last year	1.7	3.0	22.1	1.0	-0.6	-0.5	1.7	0.5	2.6	1.6	1.7	2.0	2.0	-1.5	1.7	0.8	0.8	2.1	-0.0	0.9	4.7	0.8	0.0	0.9	0.7	2.4	2.0
Qualifications: NVQ or HND or HNC or equivalent	1.7	2.0	4.0	-1.5	-1.3	-1.9	-2.0	-1.6	-1.0	-1.7	-1.8	-1.5	-1.4	-1.4	-1.4	-1.6	-1.0	-1.1	-0.7	-1.4	-0.4	-1.6	-1.2	-0.6	-1.9	-1.6	-1.5
Medication: Levothyroxine sodium	1.6	2.7	7.7	-1.6	-1.4	-1.4	-1.8	-1.1	-1.6	-1.5	-1.4	-1.7	-1.4	-1.8	-1.2	-1.0	-1.3	-2.2	-2.7	-1.2	-1.2	-1.7	-2.8	-1.1	-1.7	-1.8	-1.8
Impedance of leg (left)	1.6	7.6	20.6	3.6	2.0	2.3	2.4	2.5	2.5	2.6	2.5	2.7	3.0	2.7	2.6	1.9	2.8	1.2	3.1	2.6	3.5	2.8	0.3	2.9	3.3	4.5	3.0
Diabetes (self-reported)	1.6	2.4	7.1	-1.5	-1.7	-1.6	-1.9	-1.0	-1.4	-1.6	-1.7	-1.2	-1.3	-1.3	-1.3	-2.1	-1.5	-1.3	-2.7	-1.2	-1.5	-1.6	-0.4	-0.5	-1.7	-1.6	-2.0
Hayfever/allergic rhinitis (self-reported)	1.6	2.1	7.8	1.4	0.4	0.7	1.7	1.0	1.4	1.3	1.5	1.1	1.3	0.4	1.1	1.2	0.9	2.8	1.3	0.9	2.1	1.3	1.5	1.9	1.4	2.1	1.6
Birth weight	1.6	3.5	19.1	0.8	1.4	0.6	2.4	0.5	2.6	2.3	2.2	2.1	1.8	-0.8	1.7	1.3	1.5	2.0	2.1	0.9	4.4	1.1	0.6	0.1	1.1	2.6	2.2
Mean time to correctly identify matches	1.6	3.1	10.1	-1.6	-0.7	-0.2	-2.4	-0.8	-2.3	-1.5	-2.0	-1.5	-1.7	0.2	-1.5	-2.2	-1.9	-2.4	-2.2	-1.1	-3.2	-1.4	-0.5	-1.3	-1.7	-2.3	-2.0
Major Depression (MDD)	1.5	1.8	6.9	-1.3	-1.7	-1.9	-1.0	-1.1	-1.2	-1.4	-1.1	-1.1	-1.0	-1.2	-1.1	-1.0	-1.2	-1.3	-1.7	-1.4	-0.4	-1.1	-2.6	-1.9	-1.1	-0.9	-0.7
Bipolar Disorder (2011)	1.5	1.4	6.5	-0.9	-0.2	-0.4	0.0	-1.2	-1.8	-1.2	-1.2	0.0	-1.3	-0.5	-1.3	-0.4	0.0	-0.7	-2.5	-1.1	-1.6	-1.1	-1.7	-1.2	-0.7	-1.1	-1.8
Systolic Blood Pressure	1.5	7.7	36.2	-2.4	-0.9	-0.8	-2.8	-1.2	-3.7	-3.0	-2.9	-2.9	-3.1	0.6	-2.9	-2.8	-2.5	-4.1	-0.2	-2.1	-6.0	-2.1	-0.6	-2.6	-1.8	-3.1	-3.7
Allergy or Eczema	1.5	3.9	27.2	1.3	-0.8	-0.2	1.4	0.3	2.7	1.7	1.5	1.7	1.9	-1.3	1.6	1.1	0.7	2.9	2.5	0.8	5.2	0.8	0.6	2.4	0.9	3.2	1.8
Cardiovascular Disease	1.5	4.8	29.1	-1.5	-0.1	0.3	-2.2	-0.6	-3.1	-1.9	-2.2	-2.4	-2.3	0.7	-2.1	-1.9	-2.1	-3.0	-1.1	-1.4	-5.4	-1.4	-0.3	-2.0	-1.2	-2.6	-3.0
Vitamin and mineral supplements	1.5	2.1	5.6	-1.6	-1.8	-1.7	-1.1	-1.1	-1.1	-1.4	-1.2	-1.3	-1.4	-1.1	-1.1	-1.4	-1.4	-1.4	-0.8	-1.2	-1.7	-1.3	-1.6	-2.4	-1.8	-1.4	-1.8
Impedance of leg (right)	1.5	7.5	19.9	3.5	2.1	2.1	2.6	2.3	2.5	2.7	2.6	2.6	2.9	2.3	2.4	2.1	2.7	1.5	3.3	2.4	3.6	2.7	0.3	2.6	3.3	4.5	3.1
Mouth/teeth dental problems	1.5	2.3	7.8	1.5	1.6	1.6	0.7	2.4	1.2	1.2	1.4	1.6	1.6	2.8	1.6	1.1	2.1	0.1	0.5	2.0	-0.3	1.8	2.0	0.8	1.6	0.6	1.3
Medication: Ramipril	1.5	1.9	6.3	-1.1	-1.0	-0.4	-1.7	-0.3	-1.4	-1.2	-1.5	-1.1	-1.1	0.0	-1.0	-1.3	-1.5	-2.1	-2.3	-0.6	-2.5	-0.9	-0.8	-1.2	-1.2	-2.2	-1.2
Worrier / anxious feelings	1.5	2.9	4.4	-1.7	-1.4	-1.7	-1.9	-2.0	-1.3	-1.4	-1.8	-1.9	-1.7	-1.8	-1.6	-1.6	-1.7	-1.6	-0.9	-1.8	-1.0	-2.0	-1.7	-2.1	-1.9	-1.7	-1.6
Age at last live birth	1.5	2.1	5.1	-1.7	-1.2	-0.5	-2.1	-1.1	-1.5	-1.4	-1.7	-1.6	-1.5	-0.7	-1.1	-0.8	-1.1	-1.5	-1.2	-1.1	-1.8	-1.1	-2.0	-0.5	-1.9	-2.3	-1.7
Heart disease (siblings)	1.5	1.8	9.8	-1.4	-1.9	-1.8	-0.7	-1.1	-1.3	-1.5	-0.9	-1.1	-1.0	-1.2	-1.1	-1.1	-1.5	-1.2	-3.1	-1.1	-0.9	-1.2	-1.1	-1.4	-1.0	-0.6	-1.3
Alzheimer’s Disease (in father)	1.4	1.5	3.1	1.6	0.1	1.0	1.4	1.1	1.3	1.1	1.3	1.5	1.4	0.7	1.3	0.8	0.7	1.3	1.3	1.3	1.1	1.3	1.1	1.8	1.3	1.6	1.0
Medication: Metformin	1.4	1.9	4.3	-1.2	-1.0	-1.1	-1.4	-1.0	-1.6	-1.3	-1.4	-1.4	-1.4	-0.8	-1.5	-1.4	-1.5	-1.2	-1.7	-1.2	-2.1	-1.3	0.1	-1.6	-1.3	-1.3	-1.9
Medication: Atenolol	1.4	1.8	8.2	-1.2	-0.3	-0.0	-1.4	-0.2	-1.2	-0.8	-1.2	-1.1	-1.2	0.3	-0.9	-1.6	-1.5	-2.0	-0.7	-0.7	-2.9	-0.7	-0.7	-2.0	-1.3	-2.1	-1.7
High blood pressure (mother)	1.4	1.9	4.3	-1.6	-1.3	-1.8	-1.7	-0.7	-1.2	-1.8	-1.5	-1.1	-1.3	-0.2	-1.1	-1.4	-0.8	-1.2	-0.9	-0.9	-2.1	-1.3	-0.2	-2.0	-1.6	-1.8	-1.7
Exposure to tobacco smoke at home	1.4	1.6	5.4	-1.0	-0.6	-1.4	-0.3	-2.3	-1.5	-1.1	-1.0	-1.5	-1.6	-2.3	-1.7	-0.7	-1.6	-0.4	0.1	-2.0	0.1	-1.5	0.2	-0.8	-0.8	0.1	-0.9
Chronic bronchitis/emphysema (mother)	1.4	1.7	8.4	0.9	0.3	0.2	0.7	0.5	2.1	1.1	1.1	1.5	1.5	0.3	1.5	0.5	1.8	1.2	1.2	1.1	2.9	0.9	0.5	1.1	0.7	2.2	1.0
Shortness of breath walking on level ground	1.4	1.7	4.8	-1.6	-0.9	-1.9	-0.6	-1.8	-0.7	-0.9	-1.0	-1.4	-1.3	-2.2	-1.5	-0.8	-1.0	-0.3	-0.3	-1.8	-0.0	-1.6	-0.7	-1.9	-1.7	-1.3	-1.0
Smoking status: Previous	1.4	2.1	4.8	-1.4	-0.2	-0.1	-0.4	-1.7	-2.1	-1.1	-1.1	-1.9	-1.9	-1.7	-1.9	-0.7	-2.2	-0.7	-1.1	-1.8	-2.1	-1.3	-0.7	-0.3	-0.8	-1.3	-2.0
Wears glasses or contact lenses	1.4	1.6	5.2	1.3	1.4	1.7	0.8	1.7	0.4	0.8	0.9	0.8	1.0	2.3	1.0	1.3	0.8	0.9	-1.1	1.4	-0.9	1.5	2.2	1.7	1.3	0.5	0.7
Prostate Cancer	1.3	1.9	4.8	-1.4	-0.3	-0.8	-1.2	-0.8	-1.3	-1.4	-1.3	-1.7	-1.6	-0.7	-1.6	-0.9	-1.4	-1.4	-1.0	-1.2	-2.2	-1.2	-1.8	-1.5	-1.3	-1.8	-1.4
Medication: Ventolin 100micrograms inhaler	1.3	1.7	5.5	-1.3	-2.0	-1.7	-0.7	-1.6	-0.3	-0.9	-0.7	-0.6	-0.6	-2.1	-0.8	-2.3	-1.7	0.0	-2.0	-1.3	1.1	-1.1	-1.8	-0.7	-1.2	0.0	-0.9
Alcohol intake frequency.	1.3	2.9	5.0	-2.1	-2.0	-2.0	-1.5	-1.9	-1.4	-1.8	-1.7	-1.5	-1.8	-1.9	-1.7	-1.3	-2.2	-1.2	-0.2	-1.9	-1.3	-1.9	-1.3	-1.4	-2.0	-1.4	-2.2
Average weekly beer plus cider intake	1.3	1.9	3.7	1.3	1.3	1.3	1.6	1.6	1.1	1.1	1.5	1.6	1.6	1.5	1.4	1.2	1.6	0.8	0.3	1.5	1.4	1.6	0.2	0.8	1.8	1.5	1.9
Hand grip strength (left)	1.2	3.0	5.6	1.6	1.5	2.0	1.4	1.6	2.3	2.0	1.6	2.0	1.9	1.6	1.8	2.0	1.9	1.9	2.4	1.8	1.7	1.8	0.9	0.5	1.4	1.1	2.0
Relative age voice broke	1.2	1.8	2.8	1.2	0.6	0.9	1.1	1.5	1.6	1.4	1.4	1.5	1.7	1.1	1.6	1.6	1.5	1.0	1.0	1.5	1.6	1.4	1.0	1.2	1.2	1.5	1.4
Serious illness, injury or assault to yourself	1.2	1.4	4.3	1.2	0.9	1.2	1.6	0.9	1.1	1.3	1.3	1.2	1.0	0.7	0.9	0.9	1.0	1.8	2.1	1.0	0.7	1.2	1.2	0.8	1.2	1.1	1.4
Frequency of tiredness / lethargy in last 2 weeks	1.2	1.9	4.7	-1.4	-1.6	-1.7	-1.2	-1.7	-0.8	-1.1	-1.3	-1.3	-1.4	-1.7	-1.3	-1.1	-1.5	-0.9	-0.5	-1.5	-1.0	-1.7	-0.5	-2.2	-1.8	-1.1	-1.8
Medication for cholesterol, blood pressure or diabetes	1.2	2.0	17.0	0.7	-0.2	-1.0	1.8	-0.5	1.4	0.7	1.2	0.7	0.8	-1.7	0.4	0.3	0.7	1.9	1.6	-0.2	4.1	0.1	-0.7	0.4	0.9	3.0	1.3
Mouth/teeth dental problems: Loose teeth	1.2	1.5	5.3	1.0	-0.0	0.2	1.3	0.8	1.7	1.2	1.4	1.4	1.4	0.2	1.4	0.8	1.2	1.6	0.4	0.9	2.0	0.9	1.0	2.3	0.7	1.2	1.2
Blood Eosinophil Count	1.1	8.3	23.9	-2.5	-3.1	-2.0	-3.5	-1.1	-3.5	-3.5	-3.1	-2.9	-2.8	-0.7	-2.7	-3.8	-3.4	-2.0	-3.5	-1.8	-4.9	-2.1	-1.0	-1.0	-2.6	-4.5	-2.4
Smoking Status	1.1	2.7	8.0	-1.1	-1.0	-0.9	-0.3	-2.5	-2.4	-1.6	-1.5	-1.9	-2.1	-2.8	-2.4	-1.2	-2.4	0.4	-0.6	-2.5	-0.7	-1.9	-0.8	-0.2	-0.8	-0.3	-1.8
Systolic blood pressure, automated reading	1.1	3.1	12.2	-1.7	-1.3	-0.6	-2.5	-0.4	-2.1	-1.9	-2.1	-1.6	-1.7	0.4	-1.6	-1.9	-1.7	-2.3	-0.1	-1.1	-3.5	-1.4	-0.4	-1.0	-1.4	-2.2	-2.6
Qualifications: CSEs or equivalent	1.1	1.4	5.5	-1.4	-1.4	-1.8	-0.3	-1.7	-0.7	-1.3	-0.8	-1.1	-1.3	-2.3	-1.1	-0.9	-1.4	-0.8	1.0	-1.5	0.4	-1.4	-0.4	-0.9	-1.1	-0.2	-0.8
Asthma	1.1	2.2	19.6	0.5	-1.6	-1.3	1.0	-0.7	1.7	0.7	1.0	1.0	1.1	-2.2	0.8	-0.1	-0.4	1.9	0.6	-0.0	4.4	-0.1	-1.4	0.1	0.5	2.5	1.2
Medication: Ibuprofen (e.g. Nurofen)	1.1	1.4	3.7	-1.2	-1.7	-1.5	-1.0	-1.3	-0.6	-0.9	-1.0	-1.3	-0.9	-1.9	-1.0	-1.1	-1.3	-0.7	-1.1	-1.3	0.2	-1.4	-1.1	-1.1	-1.4	-0.7	-1.2
Glaucoma (self-reported)	1.1	1.3	5.5	-1.1	-0.9	-0.8	-1.4	-1.2	-1.5	-1.3	-1.3	-0.9	-1.1	-0.6	-1.2	-1.2	-1.0	-2.4	-0.2	-1.2	-0.9	-1.1	-1.3	-0.3	-0.8	-0.7	-1.3
Illnesses of father: High blood pressure	1.1	1.4	3.3	-1.2	-1.8	-1.0	-1.4	-0.7	-1.3	-1.1	-1.3	-1.2	-1.1	-0.6	-1.1	-0.9	-1.8	-0.7	-1.8	-0.9	-1.4	-1.0	-0.6	-0.9	-1.0	-0.9	-1.4
Past tobacco smoking	1.0	1.9	4.8	1.1	-0.1	-0.0	0.0	2.1	2.2	1.1	1.0	1.9	2.0	2.0	2.0	0.8	2.0	0.5	0.2	2.0	1.6	1.4	0.5	0.1	0.4	0.8	1.7
Hair/balding pattern: Pattern 2	1.0	1.3	4.2	1.3	1.9	1.5	1.4	0.7	0.8	1.4	1.1	0.5	0.9	1.1	0.6	1.0	0.8	-0.5	0.5	0.6	1.2	0.9	-0.9	1.2	1.6	2.0	1.2
Prospective memory result	1.0	1.2	3.5	-1.2	-1.6	-1.6	-0.4	-1.5	-0.4	-1.0	-0.7	-0.9	-0.9	-1.9	-1.0	-1.6	-1.5	0.3	-1.5	-1.2	-0.2	-1.1	-0.1	-0.5	-1.2	-0.7	-1.2
Pain type(s) experienced in last month: Hip pain	1.0	1.3	3.8	1.0	-0.2	-0.1	1.6	0.9	1.4	0.9	1.5	1.0	1.1	-0.1	1.2	1.1	0.6	1.5	-0.2	0.9	2.0	0.9	0.2	0.7	1.1	1.8	1.6
Ever smoked	1.0	1.8	6.4	-0.9	-0.3	-0.3	0.2	-2.3	-1.9	-1.0	-0.9	-1.7	-1.8	-2.5	-2.0	-0.7	-2.0	-0.2	-0.1	-2.2	-0.6	-1.5	-0.7	-0.3	-0.2	-0.1	-1.4
Cholesterol lowering medication	1.0	1.5	4.0	1.5	1.0	1.6	0.9	1.7	0.7	1.2	1.0	1.5	1.4	1.1	1.2	1.3	0.6	0.5	-0.2	1.5	0.4	1.5	0.9	2.0	1.5	1.1	0.9
Schizophrenia vs Biploar Disorder	0.9	1.1	3.5	-1.1	-1.5	-1.9	-1.4	-1.1	-0.3	-1.1	-1.1	-0.8	-0.7	-1.4	-0.6	-1.7	0.0	-0.9	0.6	-0.9	0.6	-1.3	-0.4	-1.3	-1.2	-0.3	-0.6
Ovarian Cancer	0.9	1.1	2.5	-1.2	-1.3	-1.1	-1.2	-0.8	-1.1	-1.0	-1.2	-0.8	-0.8	-0.5	-1.3	-1.1	-0.9	-1.0	-0.7	-1.1	-0.8	-1.0	-1.6	-1.3	-1.1	-1.0	-0.8
Ever had hysterectomy (womb removed)	0.9	1.0	3.8	-0.8	-0.3	-0.9	-0.4	-1.4	-1.1	-0.8	-0.7	-0.8	-1.0	-1.7	-1.2	-0.9	-0.6	-1.2	-0.6	-1.4	0.5	-1.1	-2.0	-0.5	-0.6	0.1	-0.7
Medication: Co-codamol	0.9	1.1	5.0	0.6	-0.3	-0.3	1.2	0.0	1.5	0.8	0.9	1.0	0.8	-0.6	0.8	1.1	0.7	2.2	0.8	0.4	2.2	0.7	-0.1	1.1	0.2	1.3	1.2
Average weekly fortified wine intake	0.9	1.1	4.2	-0.8	-0.9	-1.4	-1.5	-0.6	-1.0	-1.2	-1.2	-0.8	-0.8	-0.9	-1.0	-0.2	-0.7	-1.3	-2.1	-1.0	-0.3	-1.1	-1.1	-0.3	-0.9	-0.8	-1.2
Illnesses of siblings	0.9	1.2	5.6	1.2	1.4	1.4	0.7	0.5	0.7	1.2	0.8	0.6	0.9	0.8	0.8	1.0	1.1	0.4	2.4	0.7	1.4	0.8	-0.2	1.5	1.3	1.4	0.9
Qualifications: A levels/AS levels or equivalent	0.9	2.1	4.1	1.4	1.0	1.3	0.7	2.0	1.9	1.6	1.3	1.8	1.8	1.8	1.7	1.7	1.5	0.9	1.0	1.8	0.9	1.5	1.1	0.7	1.2	1.2	1.3
Mouth/teeth dental problems: Bleeding gums	0.9	1.2	2.2	-1.0	-1.1	-1.2	-1.1	-1.0	-0.8	-0.8	-1.1	-1.1	-1.0	-1.5	-0.9	-1.1	-1.3	-0.9	-1.3	-1.0	-0.4	-1.1	-1.1	-1.4	-1.4	-1.4	-0.6
Medication: Amlodipine	0.9	1.3	4.7	-0.9	1.3	0.3	-0.1	-1.2	-1.8	-0.6	-0.9	-1.4	-1.6	-0.4	-1.6	-0.9	-0.7	-1.4	-0.6	-1.4	-2.2	-0.9	-0.3	-0.8	-0.3	-1.1	-1.1
Illnesses of father: Heart disease	0.9	1.2	6.0	0.9	1.0	1.4	0.7	1.5	-0.0	0.5	0.8	0.4	0.5	2.4	0.7	0.9	1.0	0.3	0.2	1.3	-2.3	1.4	1.3	0.9	1.0	-0.6	0.5
Asthma (self-reported)	0.9	1.8	15.6	0.1	-1.7	-1.5	0.6	-1.1	1.2	0.3	0.6	0.5	0.7	-2.4	0.4	-0.4	-0.7	1.6	0.1	-0.4	4.0	-0.5	-1.5	-0.2	0.1	2.1	0.8
Diastolic blood pressure, automated reading	0.9	2.8	10.6	-1.8	-1.3	-1.1	-2.1	-0.8	-1.7	-2.0	-1.9	-1.4	-1.8	-0.2	-1.6	-1.4	-1.2	-0.8	0.0	-1.2	-3.2	-1.6	-0.2	-1.9	-1.9	-2.6	-2.2
Height	0.8	15.5	25.5	3.4	4.2	3.1	4.1	3.4	5.0	4.7	4.5	3.8	4.2	2.7	4.4	4.4	5.0	3.5	4.8	3.9	4.2	3.7	3.3	1.9	3.3	3.1	4.0
Average weekly spirits intake	0.8	1.0	2.6	-1.2	-1.2	-1.1	-1.2	-1.0	-0.8	-1.1	-1.1	-0.8	-0.9	-1.1	-0.9	-1.6	-1.2	-0.3	0.2	-1.0	-0.3	-1.1	-0.5	-0.0	-1.1	-0.8	-1.2
Fed-up feelings	0.8	1.4	6.2	-0.8	-1.5	-1.8	-0.5	-1.8	-0.3	-0.7	-0.7	-0.9	-1.1	-2.5	-1.1	-1.2	-1.5	-0.5	0.2	-1.4	0.5	-1.5	-0.8	-1.3	-1.3	-0.3	-0.8
Standing height	0.8	8.0	16.6	2.8	3.1	2.8	2.9	2.4	3.3	3.3	3.0	2.8	2.9	1.9	2.8	2.5	3.1	3.0	4.1	2.7	2.7	2.7	2.8	0.8	2.7	2.2	3.1
Ever highly irritable/argumentative for 2 days	0.8	1.0	3.5	-1.2	-0.6	-0.9	-0.6	-1.8	-0.7	-0.7	-0.7	-0.9	-1.1	-1.9	-0.9	-1.1	-0.7	-0.4	-1.0	-1.4	0.4	-1.3	-0.4	-0.7	-1.1	-0.6	-0.8
Medication: Paracetamol	0.8	1.4	3.3	-1.2	-1.0	-1.3	-1.2	-1.1	-0.5	-1.0	-1.2	-1.1	-1.2	-1.7	-1.1	-0.5	-1.2	-0.6	1.3	-1.2	-0.7	-1.5	-0.7	-0.9	-1.8	-1.8	-1.3
Forced vital capacity (FVC), Best measure	0.8	3.0	10.0	1.7	1.7	1.6	1.7	1.2	2.0	2.1	1.7	1.5	1.7	1.0	1.4	2.0	2.1	1.7	3.2	1.3	2.2	1.4	0.6	0.1	1.6	2.0	1.9
Medication for cholesterol	0.8	1.2	5.6	0.9	0.2	0.2	1.4	0.2	1.3	0.8	1.2	0.9	1.0	0.1	1.0	1.3	1.0	1.6	-0.1	0.7	2.4	0.8	-0.2	0.6	1.0	1.3	1.8
Mineral and other dietary supplements	0.8	1.1	2.2	-0.9	-1.5	-1.2	-0.6	-1.3	-0.8	-0.9	-0.8	-0.9	-0.9	-1.5	-0.9	-0.6	-1.4	-0.5	-0.9	-1.0	-0.3	-0.9	-1.5	-1.5	-1.1	-0.9	-0.5
Medication: Aspirin	0.8	1.0	9.6	0.1	1.4	1.3	-0.2	0.3	-1.2	-0.3	-0.3	-0.5	-0.6	1.2	-0.4	-0.3	-0.1	-1.3	-0.8	0.2	-3.1	0.2	0.2	-0.7	0.1	-2.0	-0.3
Medication: Paracetamol	0.8	1.3	3.0	-1.0	-1.0	-1.4	-0.7	-1.2	-0.7	-0.9	-1.0	-1.2	-1.2	-1.7	-1.1	-0.8	-1.3	-0.6	1.1	-1.3	-0.8	-1.4	-0.9	-0.9	-1.5	-1.6	-1.2
Medication: Lisinopril	0.8	1.0	7.7	-0.6	-0.6	0.2	-0.8	0.2	-1.3	-0.9	-0.9	-0.5	-0.9	0.4	-0.8	-1.1	-1.1	-1.1	-0.9	-0.3	-2.8	-0.3	1.1	0.1	-0.5	-1.4	-1.1
Alcohol drinker status: Never	0.8	1.0	3.6	0.7	0.1	0.7	1.0	0.4	1.3	1.1	1.0	1.1	1.1	0.3	1.0	0.6	0.5	0.9	1.3	0.7	1.6	0.8	1.0	1.1	0.9	1.9	0.8
Basal cell carcinoma (self-reported)	0.8	1.0	2.9	1.3	1.5	1.5	1.4	0.9	-0.0	0.7	0.9	0.3	0.5	1.4	0.5	1.4	0.6	0.1	-0.2	0.8	-0.3	1.2	0.6	1.3	1.7	0.9	1.0
Ulcerative Colitis	0.7	1.0	3.8	-0.8	-0.9	-0.8	-2.0	-0.4	-1.0	-1.1	-1.4	-1.0	-0.8	-0.0	-0.6	-0.7	-0.7	-1.5	-0.1	-0.4	-1.3	-0.9	-0.1	-0.6	-1.2	-1.4	-1.4
Respiratory disease	0.7	1.6	14.1	0.6	-1.2	-0.7	0.9	-0.4	1.4	0.8	1.0	1.0	1.1	-1.8	0.8	0.3	-0.3	2.1	-0.3	0.1	3.8	0.2	-0.7	1.0	0.5	1.9	1.3
Number of treatments/medications taken	0.7	1.3	3.9	-1.0	-0.1	-0.1	-1.1	-1.1	-1.4	-1.0	-1.2	-1.0	-1.2	-0.8	-1.2	-1.6	-1.2	-1.1	-0.2	-1.1	-2.0	-1.1	-0.9	-0.2	-1.2	-2.0	-1.4
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	3.0	1.0	1.7	1.4	0.5	1.3	0.8	0.9	0.7	1.0	0.7	1.4	0.8	1.1	1.2	-0.1	1.1	1.0	-0.1	0.8	0.1	1.0	0.8	0.5	0.7
Fluid intelligence score	0.7	1.5	3.8	1.5	1.3	1.2	0.7	1.5	0.9	0.9	1.0	1.0	1.3	1.5	1.2	1.9	1.9	-0.2	-0.8	1.4	0.7	1.1	-0.3	1.1	1.6	1.3	1.1
Father’s age at death	0.7	0.9	2.5	-1.0	-1.6	-1.4	-1.5	-0.8	-0.2	-0.8	-1.2	-0.9	-0.7	-1.0	-0.8	-0.1	-0.7	-0.7	-1.0	-0.8	0.0	-1.3	-0.0	-1.1	-1.2	-0.8	-1.1
Medication: Aspirin	0.7	0.9	8.2	0.1	0.9	1.1	-0.5	0.5	-1.1	-0.3	-0.3	-0.4	-0.5	1.0	-0.3	-0.7	-0.3	-1.3	-1.0	0.3	-2.9	0.2	-0.0	-0.2	-0.2	-2.0	-0.4
Average weekly red wine intake	0.7	1.0	2.9	-0.7	-0.9	-0.5	-1.4	-0.4	-1.2	-1.2	-1.2	-1.1	-1.0	-0.0	-1.0	-1.4	-1.2	-1.0	0.5	-0.7	-1.7	-0.7	-0.6	-0.9	-0.8	-1.4	-0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.8	2.1	1.0	0.7	1.3	0.3	1.5	0.6	1.0	0.7	1.1	1.0	1.2	1.1	1.2	0.7	0.4	0.7	1.3	-0.1	1.0	1.2	1.0	0.6	0.2	0.3
Depression (Nagel 2018)	0.6	0.9	1.8	-0.6	0.0	-0.8	-0.6	-1.2	-0.9	-0.5	-0.8	-1.2	-1.2	-1.0	-1.2	-0.6	-0.8	-1.0	0.6	-1.3	-1.3	-1.2	-0.8	-1.2	-1.0	-0.6	-1.3
Neuroticism (Nagel 2018)	0.6	1.4	2.8	-1.5	-1.1	-1.5	-1.2	-1.4	-0.3	-0.8	-1.0	-1.1	-1.0	-1.6	-1.0	-1.2	-1.3	-0.6	-0.3	-1.5	-0.3	-1.5	-0.9	-1.0	-1.7	-1.1	-1.4
Type 2 Diabetes (T2D) (2018)	0.6	1.1	4.3	-1.0	-1.0	-0.7	-1.4	-0.3	-0.8	-0.9	-1.2	-0.6	-0.8	-0.9	-0.8	-1.9	-1.2	-0.2	-2.1	-0.7	-1.1	-1.1	-0.3	-0.1	-1.2	-1.1	-1.6
Pack years adult smoking proportion	0.6	1.0	2.1	1.2	1.2	1.5	1.4	1.4	0.5	1.0	1.2	0.8	0.8	0.7	0.7	0.6	0.6	0.0	0.5	0.9	0.1	1.1	1.5	1.0	1.2	0.6	1.0
Forced vital capacity (FVC)	0.6	2.3	8.0	1.5	1.4	1.4	1.5	1.0	1.7	1.7	1.5	1.4	1.5	0.9	1.2	1.5	1.8	1.4	2.8	1.1	2.0	1.2	0.7	0.3	1.6	1.8	1.7
Medication: Simvastatin	0.6	0.8	3.4	0.6	0.8	1.4	-0.3	1.4	-0.2	0.5	0.1	0.7	0.5	1.8	0.6	0.8	0.6	-0.1	-0.7	1.2	-1.8	1.0	0.8	0.9	0.5	-1.0	0.1
Neuroticism score	0.6	1.2	4.0	-0.8	-0.4	-1.1	-0.6	-1.9	-0.7	-0.7	-0.8	-1.4	-1.3	-2.0	-1.1	-1.5	-1.0	0.0	0.2	-1.5	-0.2	-1.4	-0.4	-0.0	-1.4	-1.1	-0.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	1.8	8.2	1.1	1.8	1.2	1.2	0.9	1.5	1.6	1.1	0.9	1.1	0.7	0.9	1.9	1.8	1.3	2.9	0.8	1.5	0.9	0.4	-0.3	1.1	1.3	1.3
High blood pressure (siblings)	0.6	0.8	3.2	-1.0	-1.4	-1.0	-1.2	-0.0	-0.4	-1.1	-1.0	-0.3	-0.6	-0.1	-0.5	-1.2	-0.7	-0.1	-0.8	-0.2	-1.6	-0.5	0.5	-0.6	-1.3	-1.8	-0.8
Exposure to tobacco smoke outside home	0.6	0.9	1.9	-0.8	-0.7	-0.8	-1.1	-1.2	-0.7	-1.0	-1.1	-0.8	-1.0	-1.1	-1.0	-1.4	-0.9	-0.6	0.1	-1.1	-0.6	-0.9	0.7	0.0	-1.2	-0.9	-1.1
Emphysema/chronic bronchitis	0.6	0.7	1.8	0.7	0.4	0.5	0.7	0.6	1.2	1.2	1.1	1.0	1.2	0.0	1.0	0.8	0.6	0.8	0.5	0.9	1.3	0.7	-0.1	0.4	0.5	0.8	0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	2.1	-0.9	-1.0	-1.2	-0.9	-1.0	-0.4	-0.7	-0.7	-0.6	-0.7	-1.2	-0.5	-1.4	-0.6	-0.3	0.1	-0.8	0.1	-1.1	-0.3	-1.4	-1.0	-0.6	-1.1
Long-standing illness, disability or infirmity	0.6	0.8	2.1	-0.9	-0.9	-0.8	-0.8	-1.0	-0.7	-0.8	-0.8	-0.6	-0.8	-1.4	-0.7	-0.8	-0.8	-0.8	-0.9	-0.8	-0.6	-1.1	-1.2	-0.4	-1.3	-1.4	-0.9
Eye problems/disorders: Cataract	0.6	0.7	1.8	0.6	0.6	1.1	0.8	1.3	0.5	0.6	0.7	0.5	0.7	1.1	0.5	1.2	0.3	-0.2	0.1	0.9	-0.3	1.0	1.3	0.3	1.2	0.3	1.0
Osteoarthritis (self-reported)	0.6	0.8	6.9	0.5	0.1	-0.5	0.9	-0.9	0.8	0.1	0.6	0.5	0.3	-1.2	0.2	0.0	0.2	0.2	0.6	-0.3	2.6	-0.1	-1.6	1.0	0.3	1.4	0.9
Medication: Atorvastatin	0.6	0.7	2.3	-0.5	-0.4	-0.5	-0.1	-0.9	-1.1	-0.7	-0.6	-0.9	-1.0	-1.3	-1.0	-0.3	-1.2	0.3	-1.5	-0.9	-1.2	-0.7	-0.2	-1.1	-0.4	-1.1	-0.5
Alcohol drinker status: Previous	0.6	0.7	1.4	-1.0	-0.5	-0.7	-0.5	-0.7	-0.8	-0.8	-0.8	-0.8	-1.1	-0.8	-0.9	-0.3	-1.0	-0.7	0.4	-0.9	-1.1	-0.7	-0.6	-0.5	-1.1	-1.2	-0.8
Bipolar Disorder (2018)	0.5	0.8	3.6	0.0	1.2	1.4	-0.2	1.1	0.3	0.4	0.2	0.5	0.4	1.9	0.6	0.8	0.8	0.5	-0.0	1.0	-1.6	0.8	1.4	0.8	-0.1	-1.1	-0.3
Schizophrenia (2018)	0.5	1.1	2.1	-0.9	-0.4	-0.8	-0.8	-1.4	-1.3	-1.1	-1.2	-1.4	-1.3	-1.0	-1.4	-0.4	-0.8	-0.8	-1.0	-1.3	-0.7	-1.2	-1.2	-1.3	-0.8	-1.0	-0.9
Worry (Nagel 2018)	0.5	1.0	2.1	-1.2	-1.4	-1.4	-1.3	-1.2	-0.1	-0.6	-0.9	-0.9	-0.7	-1.4	-0.8	-0.9	-1.3	-0.8	-0.3	-1.1	0.2	-1.2	-0.9	-0.5	-1.4	-0.6	-0.8
Age at First Birth	0.5	0.8	4.5	0.5	-0.1	0.6	-0.3	1.9	0.8	0.4	0.5	0.0	1.2	2.1	1.3	-0.4	0.8	-0.1	-0.1	1.4	-0.2	1.2	0.6	1.1	0.2	-0.2	0.6
Primary Biliary Cirrhosis	0.5	0.7	5.8	0.3	1.3	0.9	-0.5	0.1	-1.4	-0.4	-0.8	-0.4	-0.8	1.1	-0.7	-0.1	0.4	-0.7	0.1	-0.2	-2.4	-0.0	-0.0	-0.8	-0.1	-1.3	-0.3
Triglycerides	0.5	0.8	3.6	0.9	1.9	1.1	0.9	0.6	0.2	0.8	0.8	0.0	0.5	0.7	0.5	1.7	1.2	1.4	0.7	0.2	0.4	0.7	0.2	1.2	0.5	-0.1	1.0
Blood White Count	0.5	3.3	9.9	2.3	0.3	1.1	1.1	2.3	1.4	1.2	1.6	2.3	2.1	1.4	1.9	0.0	1.1	1.7	0.8	1.9	2.2	1.8	2.0	3.1	2.1	2.8	1.6
Heel T-Score	0.5	3.8	9.4	-2.9	-0.9	-1.4	-1.0	-1.6	-1.8	-1.9	-1.4	-2.5	-2.2	-2.5	-1.6	-0.4	-1.5	-2.2	-3.0	-1.7	-2.6	-1.5	-1.3	0.2	-2.4	-3.1	-1.9
Hair Pigment	0.5	13.7	19.0	-3.5	-2.9	-3.4	-4.0	-3.5	-4.4	-4.3	-4.2	-3.8	-4.1	-2.5	-4.1	-4.3	-3.7	-3.2	-3.2	-3.7	-4.2	-3.9	-2.5	-2.8	-3.6	-4.2	-4.0
Severe depression (siblings)	0.5	0.6	3.1	0.6	1.8	1.2	-0.3	-0.3	-1.1	0.1	-0.4	-0.3	-0.5	1.0	-0.7	0.4	0.5	-0.5	1.6	-0.3	-1.4	-0.2	0.7	-0.5	0.5	0.0	-0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.6	1.9	-0.3	0.1	-0.6	-0.1	-1.3	-0.5	-0.2	-0.5	-1.0	-1.1	-1.4	-0.8	-0.4	-0.8	-0.3	0.4	-1.0	-1.0	-1.1	0.1	-1.1	-1.0	-0.4	-0.8
Had other major operations	0.5	0.6	3.0	0.7	1.4	0.7	0.6	-0.0	0.7	1.2	0.6	0.6	0.6	0.0	0.5	1.1	0.9	0.3	0.1	0.3	1.0	0.3	0.1	1.7	0.1	0.4	0.6
Alcohol intake versus 10 years previously	0.5	0.7	2.5	-0.8	-1.4	-1.4	-0.3	-1.0	-0.1	-0.8	-0.5	-0.2	-0.3	-1.6	-0.4	-1.2	-0.7	-0.0	-1.2	-0.7	0.7	-0.8	-1.2	-0.3	-0.8	-0.3	-0.6
Falls in the last year	0.5	0.6	1.6	-0.5	-0.7	-0.6	-0.7	-0.9	-1.0	-0.9	-0.9	-0.6	-0.8	-1.2	-0.9	-1.3	-1.2	-0.6	-0.2	-0.8	-0.4	-0.7	-0.4	-0.3	-0.7	-0.9	-0.7
Birth weight of first child	0.5	0.9	3.0	-1.1	-1.7	-1.5	-0.9	-0.8	0.5	-0.6	-0.5	-0.1	-0.2	-1.4	-0.2	-0.7	-0.7	-0.5	-1.2	-0.5	0.9	-0.7	0.7	-1.5	-1.3	-0.9	0.1
Medication: Omeprazole	0.5	0.6	1.9	0.7	1.1	1.2	0.6	0.7	0.5	0.6	0.8	0.8	0.6	1.0	0.7	-0.0	0.8	0.1	1.4	0.7	-0.0	0.6	0.9	0.8	0.9	0.4	0.6
Chest pain or discomfort	0.5	0.7	2.9	-0.3	-1.7	-1.3	-0.3	-1.0	0.0	-0.6	-0.4	-0.3	-0.3	-1.6	-0.4	-0.9	-1.0	-0.6	-0.3	-0.7	1.0	-0.8	-1.3	-1.1	-0.5	0.4	-0.1
Breast cancer (self-reported)	0.5	0.6	2.6	0.3	0.4	0.7	-0.3	1.1	0.9	0.6	0.4	0.9	1.0	1.6	1.1	0.6	0.9	-0.1	-0.5	1.2	-0.0	0.8	0.5	0.8	0.3	0.0	0.4
Medication: Omeprazole (e.g. Zanprol)	0.5	0.5	1.5	0.7	1.2	1.2	0.5	0.7	0.4	0.7	0.8	0.7	0.6	1.0	0.7	0.4	0.9	0.2	1.0	0.7	-0.1	0.7	0.7	1.1	0.8	0.2	0.6
Deep venous thrombosis (DVT) (self-reported)	0.5	0.6	1.4	-0.9	-1.2	-1.0	-0.5	-1.2	-0.5	-0.9	-0.9	-0.8	-0.8	-1.1	-0.8	-0.1	-0.7	0.7	0.9	-0.8	-0.1	-0.7	-0.6	0.1	-0.8	-0.8	-0.1
Arm predicted mass (left)	0.5	2.7	12.5	1.1	2.1	1.7	1.9	1.4	1.8	1.9	1.9	1.5	1.3	0.7	1.6	1.7	1.4	2.6	1.6	1.5	0.4	1.5	3.5	0.1	1.1	-0.2	1.4
Depressed Affect (Nagel 2018)	0.4	0.8	2.0	-1.0	-0.8	-1.4	-0.6	-1.1	-0.2	-0.7	-0.7	-0.8	-0.9	-1.4	-0.8	-1.0	-1.0	-0.1	-0.0	-1.1	-0.4	-1.1	-0.2	-0.7	-1.3	-0.9	-0.9
Crohns Disease (2017)	0.4	0.9	2.9	-0.8	-1.6	-1.4	-1.3	-0.3	-0.0	-0.8	-0.5	-0.3	-0.2	-1.1	-0.1	-0.9	-0.5	-1.3	-1.7	-0.3	0.5	-1.0	-0.3	-1.2	-1.3	-0.9	-1.0
Coronary Artery Disease (CAD)	0.4	0.5	3.9	0.1	0.7	0.8	0.1	0.0	-1.3	-0.3	-0.4	0.0	-0.6	0.9	-0.6	0.4	0.0	1.0	-0.6	-0.2	-2.0	0.2	-0.5	0.6	0.1	-0.9	-0.1
Neuroticism (2016)	0.4	0.6	1.6	-1.0	-0.2	-0.9	-0.7	-1.2	0.1	-0.5	-0.6	-0.6	-0.7	-1.1	-0.5	-1.1	0.1	-0.5	0.8	-0.9	0.2	-1.0	-0.9	-0.7	-1.3	-0.8	-0.8
Type 2 Diabetes (T2D) (2012)	0.4	0.4	5.6	-0.2	-0.4	0.0	-0.1	0.2	-0.5	-0.2	-0.2	0.0	-0.2	0.1	-0.1	1.1	-0.6	-0.3	-2.4	0.2	-1.0	-0.0	-1.0	-0.4	-0.2	-0.7	-0.2
Sensitivity / hurt feelings	0.4	0.6	4.4	-0.2	-1.3	-1.1	-0.6	-0.2	1.4	0.1	0.1	0.5	0.7	-1.1	0.7	-0.5	0.1	0.8	0.0	0.1	2.1	-0.3	-0.1	0.9	-1.0	-0.0	-0.0
Frequency of depressed mood in last 2 weeks	0.4	0.6	1.5	-0.4	-0.3	-0.5	-0.2	-1.2	-1.2	-0.6	-0.6	-1.0	-1.1	-1.0	-1.1	-0.8	-0.8	-0.4	0.2	-1.1	-1.0	-1.1	-0.5	-0.4	-0.5	0.1	-1.0
Hand grip strength (right)	0.4	1.1	2.3	0.8	0.9	1.2	0.5	1.0	1.5	1.2	0.8	1.3	1.2	1.2	1.1	1.2	1.3	0.8	1.4	1.1	1.3	1.1	-0.2	0.2	0.8	0.8	1.2
Age when periods started (menarche)	0.4	0.9	2.2	1.1	0.8	1.0	0.9	0.4	0.4	0.9	0.7	0.8	0.9	0.6	0.6	1.1	1.1	0.8	1.2	0.6	1.4	0.7	-1.1	0.6	1.3	1.5	1.0
Stomach or abdominal pain in last month	0.4	0.5	2.2	0.6	0.4	0.3	0.6	-0.3	-0.3	0.0	0.1	0.0	0.0	-0.7	-0.3	0.6	-0.3	0.6	-1.3	-0.4	1.2	-0.3	0.6	1.5	0.8	1.4	0.1
Nervous feelings	0.4	0.7	2.4	-0.6	-0.6	-0.9	-0.6	-1.2	-0.5	-0.5	-0.7	-1.0	-0.8	-1.5	-0.8	-1.2	-0.9	-0.7	-0.5	-1.2	0.6	-1.2	-0.4	-0.7	-0.7	-0.0	-0.5
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	2.4	-0.7	-0.0	-0.7	0.0	-1.4	-0.5	-0.3	-0.4	-0.9	-1.0	-1.3	-0.9	-0.4	-0.7	-0.4	-0.9	-1.1	-0.2	-1.0	-0.4	-1.5	-0.7	-0.2	-0.3
Trunk fat-free mass	0.4	2.1	10.5	0.8	1.8	1.2	1.5	1.4	1.7	1.6	1.6	1.3	1.2	0.5	1.4	1.6	1.2	2.1	1.1	1.4	0.3	1.2	3.2	-0.6	0.8	-0.6	1.3
Forced expiratory volume in 1-second (FEV1)	0.4	1.3	6.1	1.0	1.4	1.1	1.1	0.9	1.2	1.3	1.0	0.8	0.9	0.8	0.7	1.6	1.6	1.1	2.5	0.7	1.2	0.9	0.4	-0.1	1.0	1.1	1.3
Happiness	0.4	0.4	1.9	1.0	1.4	0.7	1.1	0.1	-0.1	0.3	0.7	-0.0	0.1	0.8	-0.0	1.1	0.6	-0.3	0.2	0.1	-0.5	0.5	0.5	0.9	0.9	0.5	0.6
Mouth/teeth dental problems: Dentures	0.4	0.7	3.5	-0.0	-0.5	-0.0	0.5	-0.7	0.3	0.5	0.1	0.3	0.2	-1.3	-0.0	-0.6	-0.5	1.7	1.9	-0.3	1.7	-0.1	-0.2	1.1	0.2	1.4	-0.2
Medication: Cholesterol lowering	0.4	0.6	3.7	0.3	0.4	1.0	-0.1	0.9	-0.1	0.3	0.2	0.3	0.2	1.2	0.5	0.3	0.3	0.0	-0.5	0.8	-1.9	0.7	1.1	-0.1	0.1	-1.6	0.1
Trunk predicted mass	0.4	2.2	10.7	0.9	1.9	1.3	1.6	1.4	1.8	1.7	1.7	1.4	1.2	0.6	1.5	1.7	1.3	2.1	1.1	1.4	0.4	1.3	3.3	-0.6	0.8	-0.5	1.4
Peak expiratory flow (PEF)	0.4	0.9	5.7	1.0	1.3	0.9	0.6	0.8	1.0	1.0	0.6	0.4	0.6	0.8	0.6	1.4	1.4	0.9	2.4	0.6	0.7	0.6	-0.1	0.0	0.7	0.9	0.8
Pulse wave reflection index	0.4	0.4	2.2	-0.6	0.5	0.6	-0.8	-0.1	-0.1	-0.1	-0.4	-0.4	-0.3	1.1	0.1	-0.6	0.5	0.1	0.7	0.3	-1.5	0.1	1.0	-1.1	-0.6	-1.3	-0.1
Blood clot in the leg (DVT)	0.4	0.5	1.3	-0.8	-1.1	-0.9	-0.3	-1.0	-0.3	-0.7	-0.6	-0.6	-0.6	-1.1	-0.6	0.1	-0.6	0.9	1.0	-0.7	-0.0	-0.5	-0.4	0.1	-0.8	-0.9	0.0
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	3.5	0.7	0.4	0.8	-0.2	0.3	0.4	0.4	-0.0	0.6	0.5	0.6	0.4	-0.6	0.2	1.3	1.9	0.5	0.2	0.5	1.2	1.1	0.1	0.3	0.5
Age at first live birth	0.4	0.6	4.4	0.0	0.6	1.0	-1.0	1.1	-0.2	-0.0	-0.3	0.1	0.2	2.1	0.5	0.1	1.0	-0.3	-0.3	0.8	-1.6	0.7	-0.6	0.4	-0.3	-1.2	-0.1
Eye problems/disorders: None of the above	0.4	0.5	3.0	0.6	0.7	0.2	0.8	0.1	0.9	0.8	0.8	0.6	0.6	-0.1	0.8	0.3	0.6	1.7	0.1	0.6	0.7	0.5	0.6	1.2	0.1	0.5	0.6
Medication for pain relief, constipation, heartburn	0.4	0.8	3.5	0.7	-0.0	0.0	0.9	0.7	0.6	0.3	0.7	0.8	0.9	1.2	0.7	0.6	0.8	0.8	-0.6	0.8	1.0	1.0	1.0	0.5	1.3	1.9	1.0
Commuting to job workplace: Car/motor vehicle	0.4	0.5	1.7	0.7	0.4	0.5	0.2	0.8	1.1	0.7	0.6	0.3	0.7	0.5	0.8	1.0	0.5	0.7	1.3	0.8	0.5	0.8	1.0	0.6	0.4	0.3	0.9
Illnesses of siblings: Diabetes	0.4	0.5	2.2	-0.7	-0.9	-1.3	-0.1	-0.7	-0.1	-0.5	-0.3	-0.3	-0.5	-1.5	-0.4	0.1	-0.8	0.6	-0.5	-0.6	-0.1	-0.6	0.6	-0.9	-0.9	-0.4	-0.9
Osteoporosis (self-reported)	0.4	0.4	1.7	-0.4	0.2	-0.3	-0.9	-1.0	-0.9	-0.6	-0.6	-0.4	-0.7	-0.2	-0.6	-0.8	-0.3	-1.3	0.6	-0.7	-0.6	-0.7	-0.6	-0.6	-0.4	-0.7	-0.8
Illnesses of father: None of the above (group 1)	0.4	0.4	1.3	-0.8	-0.1	-1.0	-0.7	-0.7	0.0	-0.4	-0.6	-0.3	-0.4	-0.9	-0.4	-0.4	0.1	-0.7	0.4	-0.7	0.9	-1.0	-0.7	-1.1	-0.9	-0.3	-0.4
Guilty feelings	0.4	0.5	2.1	-0.2	1.3	0.5	0.4	-1.4	-0.7	0.0	-0.1	-0.9	-1.0	-0.8	-0.7	-0.4	0.2	-0.5	0.7	-0.9	-1.1	-0.7	-0.7	-0.7	-0.4	-0.9	-0.3
Mother’s age at death	0.4	0.5	3.3	0.4	0.5	0.7	0.4	0.2	0.4	0.4	0.5	0.3	0.5	1.4	0.6	0.6	0.9	0.6	0.8	0.7	0.1	0.4	1.8	0.3	0.6	0.7	0.2
Financial situation satisfaction	0.4	0.5	1.8	0.3	0.9	0.5	0.6	0.6	1.3	1.1	0.9	1.4	0.9	0.3	1.0	0.3	0.8	0.5	0.4	0.8	1.0	0.5	-0.3	0.5	0.3	0.2	0.7
High cholesterol (Self-reported)	0.4	0.8	2.6	1.0	1.1	1.4	0.4	1.3	-0.1	0.8	0.6	0.5	0.6	1.6	0.7	1.1	0.7	-0.3	-0.1	1.1	-1.5	1.0	0.6	0.5	1.1	-0.1	0.2
Arm fat-free mass (left)	0.4	2.3	11.9	1.1	2.0	1.7	1.6	1.4	1.5	1.6	1.6	1.3	1.1	0.7	1.4	1.5	1.0	2.2	1.6	1.4	0.1	1.4	3.5	-0.1	1.0	-0.4	1.3
Ever had prostate specific antigen (PSA) test	0.4	0.5	1.7	0.7	0.4	0.8	-0.0	0.8	-0.2	-0.1	0.2	0.2	0.3	1.3	0.4	0.1	0.9	-0.7	-0.3	0.8	-0.8	0.6	1.2	1.1	0.8	0.3	0.4
Commuting to job workplace: Cycle	0.4	0.5	2.5	0.4	1.6	0.9	0.4	0.7	0.3	0.5	0.5	0.7	0.5	1.5	0.5	0.9	1.1	0.3	-0.1	0.7	-0.4	0.7	0.9	-0.1	0.6	-0.1	0.3
Myopia	0.4	0.6	4.6	0.1	1.4	1.0	-0.1	0.2	-1.0	-0.3	-0.2	-0.0	-0.4	1.4	-0.2	-0.7	0.3	-0.4	-1.3	0.1	-2.1	0.1	-0.4	0.3	0.2	-0.9	-0.3
Impedance of whole body	0.4	2.1	9.2	1.8	0.4	0.6	0.7	0.8	1.2	1.1	0.9	1.2	1.5	0.9	1.1	0.3	1.4	0.1	2.4	0.9	2.8	1.0	-1.4	1.7	1.5	3.0	1.5
Fasting Glucose	0.3	0.3	2.2	-0.0	-1.5	-0.9	-0.2	0.6	0.4	-0.2	-0.0	0.2	0.3	-0.4	0.2	0.1	-0.0	0.5	-1.0	0.1	1.0	0.0	-0.5	1.2	-0.4	0.2	-0.0
Rheumatoid Arthritis	0.3	0.4	2.0	0.7	0.6	0.7	-0.1	0.5	0.2	0.6	0.4	0.5	0.6	0.5	0.5	1.4	0.2	-0.8	0.0	0.5	0.6	0.4	-1.4	0.1	0.5	0.9	0.1
Blood Platelet Count	0.3	3.5	21.0	1.6	-1.4	-0.7	1.6	0.9	2.2	1.0	1.7	1.9	1.9	-1.1	1.5	-0.8	-0.2	1.7	0.5	1.0	4.6	0.9	1.4	1.9	1.7	4.0	2.2
Ever used hormone-replacement therapy (HRT)	0.3	0.3	1.7	-0.3	-0.4	-0.8	0.8	-0.8	0.1	0.1	0.2	-0.1	-0.1	-1.3	-0.3	0.7	-0.2	0.4	0.3	-0.6	1.2	-0.2	-0.7	-0.3	0.0	0.7	0.5
Current tobacco smoking	0.3	0.5	2.3	1.0	0.0	0.0	1.0	-0.3	-0.1	0.3	0.4	0.5	0.3	-0.6	0.1	0.2	0.2	1.4	1.1	-0.1	1.5	0.1	0.5	0.7	0.8	1.5	0.5
Taking other prescription medications	0.3	0.4	2.0	-0.8	-0.4	-0.1	-0.3	-1.0	-0.7	-0.5	-0.4	-0.4	-0.6	-0.9	-0.5	-0.7	-0.6	-0.1	-0.7	-0.7	-0.4	-0.7	-1.4	0.6	-0.6	-0.6	-0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	2.4	-1.0	0.7	0.5	-0.5	-1.0	-1.0	-0.3	-0.7	-1.0	-1.1	-0.9	-0.8	0.9	-0.3	-0.4	0.1	-0.8	-1.4	-0.6	-0.1	0.2	-1.0	-1.6	-0.8
Sitting height	0.3	2.4	9.5	1.2	1.4	0.8	1.2	1.0	2.5	1.9	1.5	1.5	1.5	-0.2	1.5	1.2	1.7	1.8	3.1	1.1	2.5	0.9	1.9	-0.2	0.7	0.7	1.8
Number of incorrect matches in round	0.3	0.4	1.8	-0.5	-0.6	-0.2	-0.9	-0.6	-0.6	-0.5	-0.8	-0.6	-0.5	-0.4	-0.4	-1.3	-1.1	-0.2	-0.9	-0.3	-0.7	-0.5	-0.3	0.3	-0.6	-1.1	-0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.7	4.2	0.1	1.9	1.5	0.8	-0.3	0.1	0.9	0.5	-0.0	-0.1	-0.2	0.0	2.0	0.7	0.6	1.6	-0.1	-0.3	0.3	0.2	1.0	0.2	-0.2	0.3
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	1.3	0.2	-0.1	-0.4	0.6	0.1	1.1	0.5	0.6	0.8	0.6	-0.3	0.8	0.3	0.7	0.8	-0.3	0.5	1.1	0.1	0.6	-0.5	-0.1	0.2	0.7
Heart attack	0.3	0.3	1.6	0.2	0.4	0.3	0.8	0.4	0.7	0.7	0.8	0.4	0.4	0.0	0.7	0.9	0.1	0.3	-0.5	0.6	-0.2	0.6	1.3	-0.6	0.1	-0.6	0.5
Pain all over the body in last month	0.3	0.4	1.1	-0.6	0.1	-0.3	-0.8	-0.5	-0.4	-0.4	-0.7	-0.4	-0.6	-0.4	-0.5	-1.0	-0.6	0.0	1.0	-0.6	-0.4	-0.4	-1.0	0.4	-0.7	-0.8	-0.4
Noisy workplace	0.3	0.4	2.5	0.4	0.1	0.6	0.2	0.8	0.9	1.0	0.6	0.7	0.7	0.7	0.8	0.0	0.5	-0.2	-0.0	0.9	-0.3	0.8	1.6	-0.0	0.3	-0.2	0.6
Depression (self-reported)	0.3	0.4	1.4	0.5	0.5	0.3	0.4	0.5	0.6	0.4	0.5	0.5	0.6	0.8	0.6	-0.2	0.6	1.2	0.8	0.5	0.5	0.4	0.9	0.1	0.5	0.9	0.4
Pulse wave Arterial Stiffness index	0.3	0.3	1.5	-0.3	0.7	0.3	-0.3	-0.1	0.1	-0.1	-0.2	-0.1	-0.2	0.8	0.1	-0.8	0.8	0.7	0.2	0.3	-1.2	0.2	1.2	-0.2	-0.3	-0.9	-0.0
Breastfed as a baby	0.3	0.3	1.4	0.6	0.9	0.9	0.5	0.4	-0.1	0.1	0.2	0.1	0.2	1.2	0.1	0.6	0.5	-0.1	-0.7	0.4	-0.6	0.6	0.1	0.9	0.8	0.2	0.4
Arm fat-free mass (right)	0.3	1.6	8.2	0.8	1.9	1.4	1.4	1.0	1.1	1.4	1.3	0.9	0.8	0.5	1.0	1.4	0.8	1.9	1.9	1.0	-0.2	1.0	2.9	-0.5	0.7	-0.7	1.0
Pulse wave peak to peak time	0.3	0.3	2.0	0.3	-0.6	-0.3	0.4	0.2	0.1	0.2	0.3	0.2	0.2	-0.8	-0.0	0.9	-0.7	-0.5	-0.1	-0.2	1.3	-0.1	-1.4	0.0	0.3	0.8	0.1
Qualifications: College or University degree	0.3	1.1	6.3	0.7	1.4	1.6	-0.6	1.4	0.1	0.5	0.0	0.3	0.5	2.5	0.7	1.6	1.4	-0.5	-0.4	1.2	-1.7	0.8	0.2	0.1	0.6	-0.7	0.2
Neck or shoulder pain in last month	0.3	0.4	2.9	0.3	-0.6	-0.3	0.7	0.2	0.6	0.1	0.5	0.3	0.3	-0.5	0.3	0.2	-0.0	1.7	0.1	0.2	1.2	0.3	-0.3	1.2	0.3	0.5	0.8
Migraine (self-reported)	0.3	0.4	1.2	0.4	0.3	0.0	0.9	0.2	0.6	0.2	0.9	0.7	0.6	1.1	0.6	1.1	0.7	-0.3	-0.3	0.6	0.3	0.7	0.6	-0.2	0.6	0.4	0.7
Medication: Ibuprofen	0.3	0.4	1.8	-0.5	-1.0	-0.9	-0.2	-0.8	0.1	-0.2	-0.2	-0.5	-0.2	-1.4	-0.3	-0.7	-0.6	0.2	-0.4	-0.6	0.8	-0.7	-0.2	-0.6	-0.7	0.1	-0.5
Comparative height size at age 10	0.3	1.8	4.5	1.2	1.3	1.3	1.4	0.9	1.7	1.6	1.5	1.4	1.3	-0.0	1.4	0.9	1.2	1.6	1.8	1.1	1.9	1.1	2.1	0.4	1.0	0.5	1.5
Number of full sisters	0.3	0.3	1.7	-0.1	-1.2	-0.8	0.2	-0.4	0.6	0.1	0.0	0.3	0.2	-0.5	0.1	0.3	0.0	1.3	1.0	-0.2	1.0	-0.2	-0.1	-0.4	-0.1	0.6	0.2
Handedness (chirality/laterality): Left-handed	0.3	0.3	0.9	0.8	-0.1	0.7	-0.2	1.0	0.4	0.6	0.4	0.7	0.6	0.7	0.6	0.6	0.1	0.3	-0.2	0.8	-0.1	0.5	0.9	0.9	0.3	0.3	0.4
Commuting to job workplace: Walk	0.3	0.4	3.1	-0.6	-0.9	-0.8	-0.4	0.1	-0.6	-0.7	-0.4	0.3	-0.1	0.2	-0.2	-0.8	-0.3	-0.4	-1.8	-0.1	-0.5	-0.3	-0.4	-0.6	-0.3	-0.4	-0.5
Smoking status: Current	0.3	0.5	2.5	0.8	0.0	0.0	0.8	-0.5	-0.2	0.1	0.3	0.4	0.2	-0.8	-0.1	0.2	0.3	1.2	1.1	-0.3	1.6	-0.1	0.3	0.6	0.7	1.4	0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	2.1	0.9	1.5	1.2	0.3	1.0	0.2	0.8	0.5	0.5	0.6	1.2	0.6	1.2	1.0	0.1	0.5	0.7	0.4	0.6	-0.2	0.9	1.0	0.9	0.6
Whole body water mass	0.3	1.4	9.2	0.4	1.4	1.0	1.2	1.0	1.4	1.3	1.2	1.0	0.8	0.2	1.1	1.2	0.9	2.0	1.1	1.0	0.0	0.8	3.0	-0.8	0.4	-1.0	1.0
Average weekly champagne plus white wine intake	0.3	0.4	1.5	0.6	0.5	0.4	0.5	0.9	0.6	0.5	0.6	0.7	0.6	1.2	0.7	0.6	0.7	1.0	-0.2	0.9	-0.1	0.8	0.8	0.3	0.3	0.2	0.6
Hearing aid user	0.3	0.3	2.1	-0.4	-0.3	-0.8	0.3	0.0	-0.3	-0.8	-0.1	-0.5	-0.6	0.0	-0.3	0.1	-0.3	0.2	-1.4	-0.2	-1.3	-0.1	0.1	0.6	-0.4	-1.0	-0.3
Eye problems/disorders: Glaucoma	0.3	0.3	1.7	-0.4	-0.7	-0.4	-0.8	-0.7	-0.8	-0.8	-0.7	-0.4	-0.5	-0.4	-0.6	-0.4	-0.3	-1.3	-0.1	-0.6	-0.1	-0.5	-0.8	0.2	-0.2	-0.0	-0.5
Basal metabolic rate	0.3	1.4	8.7	0.5	1.4	1.0	1.2	1.0	1.4	1.2	1.2	1.0	0.8	0.1	1.0	1.1	0.8	2.1	1.3	1.0	0.1	0.8	3.0	-0.7	0.4	-0.9	1.0
Pain experienced in last month	0.3	0.5	2.6	0.7	-0.1	0.8	-0.6	1.1	0.6	0.7	0.2	1.0	1.0	1.6	1.0	0.2	0.4	-0.8	0.7	1.2	-0.4	0.7	0.1	0.1	0.3	0.3	-0.1
Heart attack/myocardial infarction (self-reported)	0.3	0.4	2.2	0.2	0.5	0.4	0.8	0.4	0.7	0.7	0.7	0.4	0.4	0.1	0.6	0.8	0.1	0.4	-0.5	0.6	-0.4	0.6	1.5	-0.7	0.1	-0.5	0.4
Bipolar Disorder or Schizophrenia	0.2	0.5	2.6	-0.7	0.5	0.2	-0.7	-0.3	-0.9	-0.6	-0.9	-0.8	-0.8	0.4	-0.7	0.1	-0.1	-0.4	-0.7	-0.4	-1.6	-0.5	0.1	-0.5	-0.6	-1.5	-0.9
Reaction Time	0.2	0.4	2.9	0.1	0.4	0.9	-0.8	0.3	-1.0	-0.2	-0.5	-0.2	-0.4	1.1	-0.3	-0.5	-0.6	-0.9	-1.0	0.0	-1.7	-0.1	-0.2	-0.3	-0.2	-0.4	-0.6
Body Mass Index (BMI) (2010)	0.2	0.2	1.5	-0.6	-0.8	-0.7	0.1	-0.2	0.2	-0.1	0.1	0.0	-0.1	-0.7	0.0	0.6	0.0	0.4	-1.2	-0.0	-0.3	-0.2	-0.6	-0.3	-0.6	-1.0	-0.0
Crohns Disease (2012)	0.2	0.4	1.6	-0.6	-0.7	-0.6	-1.3	-0.1	0.2	-0.4	-0.5	-0.1	0.0	-0.4	0.3	-0.6	0.2	-1.0	-0.1	0.1	0.4	-0.6	0.1	-1.2	-0.9	-0.8	-0.6
LDL Cholesterol	0.2	0.3	1.4	0.1	0.9	0.4	0.2	0.2	0.1	0.3	0.2	0.0	0.1	0.4	0.2	0.5	1.1	0.3	1.2	0.4	-0.5	0.2	0.8	0.7	-0.1	-0.5	0.3
Schizophrenia (2014)	0.2	0.4	0.9	-0.5	0.4	-0.1	-0.8	-0.7	-0.8	-0.6	-0.8	-0.9	-0.7	-0.4	-0.7	-0.1	-0.0	-0.6	-0.4	-0.6	-0.3	-0.7	-0.4	-1.0	-0.6	-0.7	-0.5
Lung FVC	0.2	0.9	3.8	-0.6	-0.2	0.0	-0.9	-1.0	-1.6	-1.1	-1.1	-1.2	-1.2	0.1	-1.2	-0.6	-0.6	-0.9	0.5	-0.9	-2.0	-0.8	-0.6	-0.5	-0.6	-0.8	-1.3
Tanning	0.2	2.1	5.6	1.0	2.4	2.1	1.2	1.5	1.0	1.8	1.4	1.0	1.2	1.5	1.2	2.1	1.3	0.1	1.8	1.5	-0.2	1.7	2.2	0.7	1.2	0.1	1.6
Medication for hormone replacement therapy	0.2	0.2	3.0	0.1	0.7	0.2	0.5	0.1	0.2	0.6	0.3	-0.2	0.1	-0.2	0.1	0.8	0.1	-0.1	1.7	-0.0	0.4	0.1	0.2	-0.1	0.1	0.6	0.2
Diabetes (mother)	0.2	0.3	1.5	-0.3	1.2	0.1	0.2	-0.5	-0.6	-0.3	-0.2	-0.5	-0.8	-0.4	-0.7	-0.1	0.3	-0.5	-0.6	-0.7	-0.8	-0.4	-0.5	0.6	0.0	-0.3	-0.5
Townsend deprivation index at recruitment	0.2	0.3	1.4	-0.1	0.3	-0.5	1.0	-1.0	0.1	0.2	0.4	-0.3	-0.3	-1.2	-0.4	0.7	-0.1	0.8	0.4	-0.6	0.5	-0.4	-0.5	-0.7	0.1	0.8	-0.0
Bilateral oophorectomy (both ovaries removed)	0.2	0.3	2.2	0.2	0.4	-0.3	0.4	-0.5	0.3	0.3	0.3	0.2	0.2	-0.6	-0.0	0.4	0.0	-0.5	0.0	-0.3	1.5	-0.2	-1.1	0.1	0.4	1.0	0.2
Body mass index (BMI)	0.2	0.8	3.8	-1.1	-0.6	-0.7	-0.5	-0.3	-0.4	-0.6	-0.6	-0.5	-0.8	-1.2	-0.6	-0.7	-1.3	0.7	-0.5	-0.6	-1.1	-0.7	1.3	-0.7	-1.1	-1.9	-0.8
Alcohol usually taken with meals	0.2	0.3	1.0	0.8	0.6	0.9	0.1	0.8	0.1	0.3	0.0	0.3	0.3	1.0	0.2	0.4	0.6	0.1	0.4	0.5	-0.4	0.5	0.3	0.9	0.7	0.5	0.3
Had menopause	0.2	0.2	1.2	-0.5	0.0	-0.2	0.1	-0.5	-0.7	-0.3	-0.2	-0.5	-0.4	-0.7	-0.6	-0.6	-0.3	-1.1	0.0	-0.6	0.0	-0.3	-0.7	-0.1	0.0	-0.1	-0.3
Weight	0.2	1.0	6.7	0.3	1.0	0.8	0.8	0.9	1.2	1.0	0.9	0.9	0.6	-0.1	0.8	0.5	0.3	2.0	1.4	0.7	0.0	0.6	2.6	-0.3	0.2	-0.9	0.7
Impedance of arm (right)	0.2	0.8	4.9	0.8	-0.5	-0.1	-0.2	0.5	0.8	0.4	0.2	0.8	1.0	0.5	0.6	-0.6	0.9	-0.3	1.1	0.5	2.2	0.4	-1.5	1.3	0.6	1.8	1.0
Arm fat percentage (right)	0.2	0.6	2.6	-1.0	-0.9	-1.0	-0.8	-0.1	0.0	-0.7	-0.7	-0.3	-0.5	-1.0	-0.4	-1.4	-1.0	0.3	-0.3	-0.4	-0.5	-0.6	0.6	-0.5	-1.1	-1.6	-0.5
Time employed in main current job	0.2	0.2	0.7	-0.2	-0.4	-0.0	-0.6	-0.6	-0.5	-0.5	-0.6	-0.6	-0.4	-0.2	-0.5	-0.8	-0.8	0.2	0.3	-0.4	-0.3	-0.3	-0.5	0.1	-0.4	-0.3	-0.2
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	1.6	0.5	0.7	0.6	0.2	0.3	-0.5	0.1	-0.0	0.0	-0.0	1.3	-0.2	0.6	0.4	0.1	-0.2	0.1	-0.9	0.4	-0.5	-0.1	0.5	0.1	-0.0
Impedance of arm (left)	0.2	0.8	5.4	0.5	-0.7	-0.6	-0.4	-0.0	0.4	0.1	-0.2	0.3	0.5	-0.1	0.2	-0.7	0.6	-0.6	1.2	-0.1	2.2	-0.2	-2.3	0.7	0.3	1.8	0.5
Length of working week for main job	0.2	0.2	1.5	-0.4	0.1	0.3	-0.2	0.0	-0.8	-0.1	-0.2	-0.5	-0.3	-0.0	-0.4	0.8	-0.2	-1.2	-0.9	-0.2	-0.8	-0.1	-0.2	0.3	0.1	-0.4	-0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	2.6	0.4	0.1	-0.6	0.6	-0.1	0.8	0.3	0.7	0.3	0.5	-0.3	0.5	-0.6	0.4	0.2	0.4	0.1	1.6	0.1	-0.3	0.2	0.2	0.7	0.8
Hair/balding pattern: Pattern 4	0.2	0.5	3.0	0.8	1.7	1.1	1.0	-0.1	-0.2	0.8	0.8	0.1	-0.0	0.3	0.1	0.4	0.6	0.6	1.2	0.2	-0.9	0.4	1.2	-0.2	0.7	-0.3	0.1
Gout (self-reported)	0.2	0.2	3.0	0.3	0.1	-0.0	-0.1	0.1	0.4	0.0	-0.1	0.2	0.2	0.4	0.1	-0.0	0.3	-0.1	1.7	0.1	0.4	0.1	1.3	0.4	0.3	0.6	0.1
Number of full brothers	0.2	0.3	1.0	-0.1	0.5	-0.7	0.7	-0.2	0.7	-0.1	0.4	0.1	-0.0	-0.9	-0.1	-0.9	0.5	0.9	-0.3	-0.4	1.0	-0.1	-0.4	-0.5	-0.2	-0.1	0.6
Arm predicted mass (right)	0.2	1.3	8.1	0.5	1.6	1.0	1.3	0.8	1.0	1.2	1.1	0.7	0.6	0.1	0.8	1.3	0.6	1.9	1.4	0.7	-0.2	0.8	2.8	-0.7	0.5	-0.8	0.8
Illness, injury, bereavement, stress in last 2 years	0.2	0.3	0.9	0.1	-0.6	0.1	-0.1	0.6	0.3	0.1	0.3	0.4	0.7	-0.1	0.8	0.4	-0.3	-0.3	-0.9	0.7	0.8	0.4	-0.9	0.3	0.3	0.5	-0.1
Supplements: Vitamin C	0.2	0.2	1.0	-0.1	1.0	0.5	-0.4	-0.2	-0.4	-0.1	-0.6	-0.7	-0.4	-0.0	-0.5	-0.3	-0.0	0.2	0.7	-0.4	-0.3	-0.3	0.6	0.1	0.1	-0.4	-0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.3	1.1	-0.7	-0.1	-0.3	-0.1	-0.9	-0.3	-0.4	-0.3	-0.6	-0.6	-1.1	-0.6	-0.4	-0.4	0.1	0.4	-0.8	0.2	-0.6	0.5	-0.0	-0.4	-0.1	-0.2
Whole body fat-free mass	0.2	1.2	8.0	0.4	1.4	0.9	1.1	0.9	1.3	1.2	1.1	0.8	0.7	0.0	0.9	1.1	0.8	1.9	1.0	0.9	-0.0	0.7	2.8	-0.8	0.3	-1.0	0.9
Arm fat percentage (left)	0.2	0.9	3.0	-1.3	-1.1	-1.2	-1.0	-0.4	-0.2	-0.9	-0.9	-0.6	-0.8	-1.4	-0.7	-1.6	-1.3	0.1	-0.2	-0.8	-0.6	-1.0	0.1	-0.8	-1.3	-1.7	-0.8
Loneliness, isolation	0.2	0.3	2.5	0.2	-0.0	-0.2	0.6	-0.4	-0.4	-0.3	0.1	-0.5	-0.5	-0.9	-0.4	0.4	-0.2	0.8	0.0	-0.4	-0.8	-0.4	1.6	0.1	-0.0	0.1	-0.2
Qualifications: nursing, teaching	0.2	0.3	0.9	0.3	0.6	1.0	0.3	0.8	0.8	0.6	0.5	0.5	0.5	0.8	0.7	0.7	0.5	0.4	-0.0	0.8	-0.3	0.7	0.1	0.3	0.2	-0.4	0.8
Back pain experienced in last month	0.2	0.3	1.9	-0.4	0.3	-0.2	0.8	-1.0	-0.6	-0.1	-0.0	-0.6	-0.6	-1.4	-0.8	0.4	-0.4	0.5	-0.3	-1.0	0.7	-0.5	0.1	-0.2	0.1	0.5	-0.0
Ever taken oral contraceptive pill	0.2	0.3	2.4	-0.1	0.2	-0.5	0.6	-0.2	0.5	0.2	0.3	0.2	0.0	-0.8	0.2	-0.8	0.5	1.5	0.4	-0.1	0.9	-0.1	-0.3	0.2	-0.3	0.7	0.3
Commuting to job workplace: Public transport	0.2	0.2	0.6	0.5	0.3	0.4	0.8	0.1	0.1	0.5	0.5	0.6	0.3	0.2	0.3	-0.5	-0.1	0.3	-0.5	0.3	0.5	0.5	-0.6	0.2	0.5	0.3	0.8
Irritability	0.2	0.4	1.8	0.6	1.3	1.2	0.5	0.2	-0.0	0.7	0.5	0.1	0.1	0.3	0.3	0.6	0.2	0.6	1.3	0.3	-0.2	0.5	0.2	0.6	0.4	0.2	0.4
Ever depressed for a whole week	0.2	0.2	0.9	-0.1	-0.3	-0.8	0.2	-0.1	0.9	0.2	0.3	0.3	0.4	-0.3	0.6	0.3	0.8	0.3	-0.5	0.3	0.9	-0.0	-0.2	0.1	-0.4	0.2	0.2
Pack years of smoking	0.2	0.3	1.2	0.7	0.7	1.1	0.7	1.0	-0.1	0.5	0.5	0.3	0.4	0.5	0.3	0.2	0.1	-0.6	0.1	0.6	-0.5	0.7	1.0	0.7	0.7	-0.1	0.5
Intelligence (Savage-Jansen 2018)	0.1	0.4	1.6	0.6	0.1	0.2	0.1	0.6	1.2	0.4	0.4	0.7	0.7	0.2	0.7	0.4	1.1	0.3	0.2	0.7	1.3	0.4	-0.4	0.3	0.3	0.9	1.0
Verbal and Numeric Reasoning (VNR)	0.1	0.2	0.9	0.2	-0.2	-0.1	-0.2	0.3	0.3	-0.1	-0.1	0.0	0.2	0.1	0.1	0.8	0.7	-0.2	-1.0	0.2	0.6	0.0	-0.2	0.1	0.3	0.6	0.3
Mean Putamen Volume	0.1	0.1	0.7	-0.0	-0.1	-0.0	0.4	-0.3	0.1	0.3	0.1	-0.1	-0.1	-0.9	-0.1	0.2	-0.3	0.7	-0.4	-0.2	0.3	-0.2	-0.6	-0.4	-0.1	-0.4	0.1
BMI	0.1	0.3	2.4	-0.1	0.2	0.2	0.2	0.4	0.2	0.1	0.2	0.1	-0.0	-0.3	0.2	-0.3	-0.6	0.9	0.7	0.2	-0.7	0.2	1.3	-0.2	-0.2	-1.6	0.2
Lung FEV1/FVC ratio	0.1	0.5	1.8	-0.8	0.4	-0.5	-0.2	-0.8	-0.6	-0.5	-0.5	-1.1	-0.9	-1.3	-0.9	0.1	-0.2	-0.3	1.3	-1.1	0.0	-0.9	-0.7	-0.0	-0.6	-0.9	-0.4
Hearing difficulty/problems: Yes	0.1	0.2	1.0	0.5	-0.2	0.1	0.4	0.3	0.8	0.2	0.4	0.3	0.4	0.2	0.5	0.3	0.4	-0.1	-0.5	0.5	0.3	0.5	0.0	1.0	0.2	0.3	0.6
Eye problems/disorders: Diabetes related eye disease	0.1	0.2	1.7	-0.1	0.0	-0.5	0.1	0.2	-0.1	-0.3	0.0	0.1	-0.0	-0.1	-0.1	-0.8	0.0	-0.0	-0.5	-0.0	-0.6	0.0	1.3	-0.4	-0.2	-0.5	-0.4
Angina	0.1	0.2	0.6	0.2	0.2	0.7	0.8	0.2	0.0	0.5	0.7	0.4	0.2	0.1	0.4	-0.1	-0.4	-0.3	-0.2	0.4	-0.7	0.6	0.4	-0.2	0.3	-0.5	0.3
Supplements: Zinc	0.1	0.1	0.3	0.0	0.5	-0.2	0.5	-0.2	0.0	-0.1	0.1	-0.4	-0.2	-0.2	-0.1	-0.0	0.3	0.2	-0.5	-0.1	-0.0	-0.2	0.1	-0.4	0.1	0.5	-0.1
Leg fat-free mass (left)	0.1	0.6	4.4	-0.5	0.5	0.1	0.4	-0.1	0.5	0.3	0.3	-0.0	-0.3	-1.0	0.0	0.2	-0.2	1.4	0.8	-0.1	-0.5	-0.2	2.1	-1.4	-0.6	-1.8	0.0
Trunk fat percentage	0.1	0.2	1.5	-0.3	-0.2	-0.1	-0.2	0.2	0.3	0.0	-0.2	0.1	-0.0	-0.7	-0.0	-0.8	-0.6	0.7	1.2	-0.1	0.2	-0.2	1.0	0.2	-0.4	-0.8	-0.0
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	1.2	0.1	-0.3	0.2	-0.1	0.1	-0.1	-0.0	-0.2	0.1	0.1	0.0	-0.2	0.8	-0.2	0.1	0.4	0.1	0.1	0.1	1.1	0.4	0.1	0.0	0.2
Leg predicted mass (left)	0.1	0.6	5.0	-0.4	0.6	0.2	0.5	0.0	0.6	0.4	0.4	0.1	-0.1	-0.9	0.1	0.4	-0.1	1.5	0.9	0.0	-0.4	-0.1	2.2	-1.2	-0.4	-1.7	0.2
Trunk fat mass	0.1	0.4	3.3	-0.1	0.2	0.2	0.2	0.5	0.7	0.4	0.2	0.4	0.3	-0.4	0.3	-0.4	-0.2	1.2	1.5	0.3	0.1	0.2	1.8	-0.0	-0.1	-0.9	0.3
Hearing difficulty/problems with background noise	0.1	0.1	0.6	0.2	0.1	-0.2	0.1	-0.2	-0.1	-0.3	-0.1	-0.4	-0.4	0.2	-0.3	-0.4	-0.1	-0.7	-0.4	-0.1	-0.6	-0.1	-0.3	0.8	0.1	-0.3	0.3
Qualifications: None of the above	0.1	0.3	1.4	-0.4	-0.1	-0.3	0.8	-1.1	-0.4	-0.0	0.2	-0.1	-0.2	-1.2	-0.5	-0.3	-0.7	0.3	-0.2	-0.8	0.8	-0.2	0.7	0.1	0.2	0.6	-0.3
Hip circumference	0.1	0.5	2.4	-0.2	-0.4	-0.6	-0.0	-0.2	0.7	0.0	-0.1	0.1	-0.1	-1.3	-0.1	-0.2	-0.4	1.4	1.4	-0.3	0.6	-0.5	1.5	-0.8	-0.7	-0.9	0.2
Hair/balding pattern: Pattern 3	0.1	0.2	1.5	-0.1	-1.2	-0.4	-0.3	0.2	-0.4	-0.8	-0.2	0.1	-0.1	0.4	-0.0	-0.6	-0.2	0.2	0.2	-0.0	0.1	0.0	0.1	0.0	0.2	0.5	-0.1
Medication: Lansoprazole	0.1	0.1	0.6	0.0	0.6	0.4	0.5	-0.2	-0.5	-0.0	-0.1	-0.3	-0.4	-0.4	-0.4	0.8	-0.4	-0.1	-0.6	-0.3	-0.7	0.1	-0.2	-0.3	0.1	-0.3	0.0
Arm fat mass (right)	0.1	0.4	2.8	-0.5	-0.0	-0.2	0.0	0.3	0.5	0.0	0.0	0.2	-0.0	-0.6	0.1	-0.5	-0.5	1.1	0.7	0.0	-0.4	-0.1	1.7	-0.5	-0.5	-1.4	-0.0
Tense / ‘highly strung’	0.1	0.2	1.1	-0.2	0.3	0.1	0.0	-0.7	-0.4	-0.0	-0.1	-0.3	-0.4	-0.5	-0.5	-1.0	-0.5	0.1	-0.3	-0.6	-0.2	-0.4	-0.2	-0.1	-0.4	-0.6	-0.1
Qualifications: O levels/GCSEs or equivalent	0.1	0.1	0.9	0.1	0.5	0.1	-0.0	0.2	0.3	0.3	0.0	0.2	0.1	-0.1	-0.1	0.3	0.2	-0.5	0.9	-0.0	0.3	-0.2	-0.4	-0.7	0.2	0.2	0.3
Headache pain in last month	0.1	0.2	1.0	0.5	0.5	-0.2	0.9	-0.2	0.3	0.1	0.2	-0.2	-0.2	-0.8	-0.3	0.3	0.1	0.8	1.0	-0.4	0.5	-0.1	0.8	0.1	0.1	-0.1	0.6
Body fat percentage	0.1	0.2	1.2	-0.2	-0.2	-0.2	-0.1	0.3	0.4	0.0	-0.1	0.2	0.1	-0.6	0.1	-0.8	-0.5	0.9	1.0	-0.0	0.1	-0.1	1.1	0.2	-0.3	-0.7	0.0
Leg fat percentage (right)	0.1	0.4	1.7	0.5	0.2	0.3	0.5	0.8	0.8	0.5	0.5	0.7	0.5	-0.2	0.5	-0.1	-0.1	1.2	1.3	0.5	0.5	0.5	1.3	0.8	0.3	-0.0	0.5
Worry too long after embarrassment	0.1	0.2	0.8	-0.2	0.3	-0.1	-0.3	-0.6	-0.2	-0.1	-0.3	-0.7	-0.5	-0.5	-0.4	-0.1	-0.2	0.3	0.1	-0.6	-0.2	-0.5	-0.5	0.9	-0.3	-0.3	-0.6
Angina (self-reported)	0.1	0.1	0.7	0.2	0.1	0.5	0.8	0.1	0.0	0.4	0.7	0.4	0.2	-0.2	0.3	-0.2	-0.4	-0.1	-0.4	0.3	-0.5	0.5	0.4	-0.3	0.3	-0.4	0.3
Medication: Allopurinol	0.1	0.1	0.7	-0.4	0.1	-0.3	-0.0	-0.3	-0.1	-0.3	-0.3	-0.4	-0.4	0.2	-0.4	0.2	0.1	-0.4	0.3	-0.4	-0.5	-0.2	0.2	-0.8	-0.1	-0.1	-0.2
Whole body fat mass	0.1	0.4	2.9	-0.3	0.1	-0.1	0.1	0.3	0.5	0.2	0.1	0.3	0.1	-0.6	0.1	-0.5	-0.4	1.2	1.2	0.1	-0.1	-0.0	1.7	-0.2	-0.4	-1.1	0.1
Leg fat mass (right)	0.1	0.5	3.6	0.3	0.6	0.4	0.6	0.7	0.8	0.5	0.6	0.6	0.4	-0.2	0.5	0.1	-0.1	1.3	1.3	0.5	-0.0	0.5	1.9	0.2	0.2	-0.7	0.5
Overall health rating	0.1	0.2	1.2	0.1	0.1	-0.6	0.6	-0.7	0.3	-0.2	0.2	-0.2	-0.3	-1.1	-0.1	-0.4	-0.1	0.6	-0.3	-0.5	0.5	-0.4	0.5	0.9	-0.5	-0.2	-0.1
Had major operations	0.1	0.2	1.0	0.2	-0.2	0.3	-0.2	0.4	0.4	0.1	0.2	0.3	0.4	0.3	0.5	0.1	0.1	-0.9	-1.0	0.5	0.1	0.3	-0.1	1.0	0.1	-0.1	0.2
Family relationship satisfaction	0.1	0.1	0.6	0.4	0.1	0.6	0.4	0.4	-0.0	0.3	0.4	0.3	0.1	-0.1	0.1	-0.0	-0.1	-0.8	-0.4	0.2	-0.8	0.1	0.1	-0.2	0.2	-0.2	0.0
Knee pain experienced in last month	0.1	0.2	1.1	-0.1	0.9	0.0	1.0	-0.3	0.2	0.2	0.6	-0.1	-0.1	-0.5	-0.0	0.8	0.1	0.5	-0.9	-0.2	0.2	0.0	0.5	0.1	0.2	0.0	0.3
Leg fat-free mass (right)	0.1	0.5	4.0	-0.6	0.5	0.2	0.3	-0.0	0.4	0.2	0.2	-0.1	-0.2	-0.8	0.0	0.2	-0.2	1.2	0.5	-0.1	-0.7	-0.2	2.0	-1.3	-0.6	-1.8	0.0
Mood swings	0.1	0.1	0.5	0.0	0.4	-0.0	0.1	-0.5	0.1	0.0	-0.0	-0.3	-0.3	-0.4	-0.2	-0.4	-0.0	0.7	0.6	-0.3	0.1	-0.2	0.5	0.3	-0.3	-0.3	0.1
Friendships satisfaction	0.1	0.2	0.7	-0.1	0.2	0.3	0.1	-0.4	-0.4	0.1	0.0	-0.4	-0.3	-0.3	-0.4	-0.4	-0.8	-0.4	-0.7	-0.3	-0.7	-0.2	0.3	-0.6	-0.3	-0.8	0.1
Leg predicted mass (right)	0.1	0.5	3.9	-0.6	0.5	0.1	0.2	-0.1	0.4	0.2	0.2	-0.1	-0.3	-0.8	0.0	0.2	-0.2	1.1	0.5	-0.1	-0.7	-0.2	2.0	-1.3	-0.6	-1.9	-0.0
Arm fat mass (left)	0.1	0.4	2.0	-0.6	-0.2	-0.4	-0.1	0.2	0.4	-0.1	-0.1	0.0	-0.2	-0.8	-0.1	-0.7	-0.7	0.9	0.6	-0.2	-0.3	-0.3	1.3	-0.7	-0.7	-1.4	-0.2
Number of self-reported non-cancer illnesses	0.1	0.2	1.2	-0.2	0.1	0.2	-0.2	-0.4	-0.2	-0.1	-0.1	-0.2	-0.3	-0.2	-0.2	-0.8	-0.5	0.2	0.2	-0.2	-0.7	-0.3	-0.3	1.1	-0.4	-0.7	-0.5
Supplements: Fish oil (including cod liver oil)	0.1	0.2	0.5	-0.6	-0.6	-0.5	-0.7	-0.1	-0.1	-0.3	-0.4	-0.2	-0.1	-0.6	-0.1	-0.3	-0.2	-0.4	-0.4	-0.3	0.6	-0.6	0.5	0.2	-0.4	-0.0	-0.7
Leg fat percentage (left)	0.1	0.4	1.6	0.5	0.1	0.3	0.3	0.8	0.7	0.3	0.3	0.7	0.5	-0.0	0.5	-0.3	-0.1	1.1	1.2	0.5	0.2	0.5	1.3	1.0	0.2	-0.1	0.4
Age started oral contraceptive pill	0.1	0.2	1.0	-0.1	-0.5	-0.3	-0.8	0.2	0.2	-0.3	-0.6	0.4	0.1	0.4	-0.1	-0.1	-0.1	-0.7	0.4	0.1	-0.2	-0.0	-0.5	1.0	-0.5	-0.2	-0.4
Leg fat mass (left)	0.1	0.4	3.3	0.2	0.4	0.3	0.4	0.7	0.6	0.4	0.4	0.5	0.3	-0.2	0.4	-0.1	-0.2	1.2	1.3	0.4	-0.2	0.3	1.8	0.2	0.0	-0.8	0.3
Chronotype (morning person)	0.0	0.1	0.6	-0.1	-0.2	0.3	-0.4	0.4	-0.1	0.0	-0.1	-0.0	-0.1	0.1	-0.0	-0.1	-0.3	-0.5	0.1	0.1	-0.8	0.0	0.5	-0.4	-0.3	-0.5	-0.2
Comparative body size at age 10	0.0	0.1	0.5	-0.3	0.3	0.4	0.2	-0.1	-0.2	0.1	0.1	-0.3	-0.2	-0.3	-0.1	0.7	-0.5	0.2	-0.6	-0.1	-0.6	-0.0	0.3	-0.7	-0.1	-0.6	-0.2

Hub : Genes

PPP2R1B

Models

Trait associations