Best TWAS P=1.22e-09 · Best GWAS P=6.34e-08 conditioned to 0.0685
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellar Hemisphere | BBS2 | 0.24 | 0.17 | lasso | 10 | 0.17 | 3.2e-05 | -5.3 | -5.2 | 1.7e-07 | 0.94 | 0.03 | 0.96 | FALSE |
| 2 | GTEx | Muscle Skeletal | OGFOD1 | 0.14 | 0.14 | lasso | 5 | 0.15 | 9.7e-15 | -5.4 | 5.5 | 4.2e-08 | -0.98 | 0.02 | 0.98 | FALSE |
| 3 | GTEx | Pituitary | BBS2 | 0.26 | 0.00 | enet | 13 | 0.00 | 2.9e-01 | 3.0 | -6.1 | 1.2e-09 | 0.67 | 0.04 | 0.46 | TRUE |
| 4 | YFS | Blood | AMFR | 0.22 | 0.28 | lasso | 18 | 0.34 | 1.0e-116 | -5.1 | 5.2 | 1.5e-07 | -0.91 | 0.05 | 0.94 | FALSE |