Hub : Genes

AMFR

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1910	0.0420	1.4e-09	0.115	0.101	0.105	0.105	0.102	8.2e-14	2.8e-12	9.6e-13	9.6e-13	2.2e-12
2	GTEx	Artery Coronary	0.2420	0.0920	8.7e-03	0.023	NA	-0.009	NA	-0.005	5.5e-02	NA	9.8e-01	NA	5.0e-01
3	GTEx	Artery Tibial	0.1963	0.0528	4.0e-05	0.063	NA	0.069	NA	0.093	1.2e-05	NA	4.0e-06	NA	9.0e-08
4	GTEx	Cells Transformed fibroblasts	0.1670	0.0540	8.7e-04	0.103	NA	0.062	NA	0.094	4.2e-08	NA	1.9e-05	NA	1.6e-07
5	GTEx	Heart Left Ventricle	0.1795	0.0678	4.2e-03	0.075	NA	0.004	NA	0.026	8.0e-05	NA	1.8e-01	NA	1.5e-02
6	GTEx	Skin Sun Exposed Lower leg	0.1620	0.0520	1.1e-04	0.005	NA	0.030	NA	0.044	1.2e-01	NA	1.6e-03	NA	1.5e-04
7	GTEx	Thyroid	0.0730	0.0310	6.3e-03	-0.003	NA	0.000	NA	-0.002	5.9e-01	NA	3.1e-01	NA	5.7e-01
8	YFS	Blood	0.2195	0.0287	0.0e+00	0.277	0.336	0.340	0.333	0.341	3.0e-91	1.7e-114	3.0e-116	4.5e-113	1.0e-116
9	TCGA	Brain Lower Grade Glioma	0.0612	0.0353	4.3e-03	0.056	0.021	0.035	NA	0.047	5.9e-07	1.8e-03	6.1e-05	NA	4.0e-06
10	TCGA	Prostate Adenocarcinoma	0.0379	0.0203	1.2e-03	0.038	0.027	0.016	NA	0.029	7.5e-05	7.7e-04	7.4e-03	NA	4.5e-04

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Bipolar Disorder (2018)	0.3	0.4	1.1	0.7	-1.0	-0.0	-0.1	0.3	-0.9	0.4	-0.8	-1.0	-0.1
Bipolar Disorder or Schizophrenia	0.4	1.1	2.4	1.5	-1.0	1.0	-0.4	-0.6	0.8	0.8	-1.4	-1.2	1.1
Depressed Affect (Nagel 2018)	0.2	0.4	1.1	0.1	-0.7	-0.4	-0.5	0.2	0.1	0.9	-1.1	-0.9	-0.2
Depression (Nagel 2018)	0.2	0.3	1.3	0.4	-1.1	-0.5	0.3	0.3	-0.6	-0.3	0.2	-0.4	-0.3
Intelligence (Savage-Jansen 2018)	0.3	0.9	3.3	-0.9	-0.2	-1.3	-0.9	-0.1	-1.8	-0.3	1.5	0.6	0.1
Neuroticism (Nagel 2018)	0.3	0.7	1.7	0.7	-1.2	-0.2	-0.5	-0.5	0.8	0.9	-1.1	-1.3	0.5
Schizophrenia (2018)	0.6	1.2	2.9	1.4	-0.5	1.3	-0.4	-1.1	1.7	0.7	-1.2	-0.7	1.5
Schizophrenia vs Biploar Disorder	0.4	0.5	1.1	-0.7	0.7	-1.0	-0.1	0.7	-0.6	-0.3	1.0	0.6	-1.0
Worry (Nagel 2018)	1.1	2.3	5.5	2.3	-1.1	0.6	0.1	-0.5	2.2	1.9	-2.4	-1.2	0.7
Alzheimer’s Disease (in mother)	2.0	2.3	6.7	-0.2	-2.6	-1.6	-1.7	-1.0	1.1	1.4	-1.0	-2.2	0.9
Alzheimer’s Disease (in father)	0.6	0.7	2.1	1.1	0.5	0.6	1.1	1.4	-0.1	-0.1	0.2	-0.0	-1.2
Alzheimer’s Disease (including proxy)	1.5	2.2	5.9	0.5	-2.3	-0.9	-1.1	0.1	1.4	2.1	-1.3	-2.4	-0.1
Crohns Disease (2017)	0.2	0.5	1.3	0.4	-0.3	-0.2	-0.9	-1.1	0.5	-0.2	-0.8	-0.5	1.2
Irritable Bowel Disease (IBD)	0.6	1.4	2.9	1.0	-0.7	-0.1	-1.4	-1.2	1.6	0.6	-1.7	-1.0	1.5
Ulcerative Colitis (UC)	0.7	1.2	3.4	1.0	-0.8	0.1	-1.0	-0.5	1.8	1.1	-1.8	-1.1	0.7
Major Depression (MDD)	1.9	2.3	6.1	2.5	-0.2	0.8	-0.8	-1.4	2.3	2.0	-1.8	0.2	1.1
Reaction Time	0.7	1.3	4.8	-0.6	0.2	-0.1	0.7	0.9	-0.3	-1.6	2.2	2.0	-0.6
Verbal and Numeric Reasoning (VNR)	0.4	1.0	2.8	-1.5	-0.2	-1.6	-1.3	-0.3	-1.7	0.1	0.9	-0.2	0.1
Breast Cancer	4.7	11.3	27.5	-3.2	1.2	-0.8	3.1	3.3	-3.8	-4.9	5.2	1.6	-3.4
Ovarian Cancer	0.2	0.2	0.8	-0.7	0.5	-0.4	0.1	-0.2	0.5	0.6	0.3	0.9	-0.0
Prostate Cancer	0.3	0.4	1.2	1.1	-1.1	-0.2	0.0	-0.4	-0.8	-0.5	-0.3	-0.6	0.7
Age at First Birth	0.6	0.9	2.6	1.2	-0.8	1.1	0.7	0.3	1.1	1.1	-1.6	-0.6	-0.3
Bipolar Disorder (2011)	0.6	0.5	1.5	1.2	-0.5	0.3	-0.3	-0.9	0.4	0.3	-1.0	-0.2	1.2
Body Mass Index (BMI) (2010)	1.3	1.8	4.4	-1.5	-2.1	-1.1	-0.2	0.2	-1.5	-1.3	1.8	-1.7	-0.1
Coronary Artery Disease (CAD)	0.5	0.5	1.6	-0.2	1.3	0.9	0.9	0.1	-0.6	-1.1	0.4	0.5	-0.3
Crohns Disease (2012)	0.3	0.5	2.1	0.1	-0.2	-0.6	-0.4	-0.2	-1.1	-1.4	0.5	0.6	0.6
Mean Putamen Volume	0.6	0.7	2.5	-1.6	0.1	-0.9	-1.2	-1.0	0.2	0.0	0.5	-0.5	0.6
Fasting Glucose	0.3	0.4	1.1	-0.8	0.3	-0.3	-0.6	-0.8	1.1	0.0	-0.1	-0.4	0.6
HbA1C	0.4	0.5	1.3	0.5	1.1	0.9	0.2	0.3	1.1	0.5	-0.0	0.9	0.2
HDL Cholesterol	1.7	2.9	7.1	2.0	0.2	-0.1	-0.3	2.5	1.8	2.2	-1.8	0.6	-2.7
LDL Cholesterol	1.4	2.2	5.9	2.3	-0.4	1.0	1.1	1.0	1.0	2.4	-2.1	0.9	-0.7
Lupus	3.0	4.6	10.1	1.4	-1.5	-0.0	-1.8	-3.2	2.2	2.2	-2.6	-2.2	2.6
Neuroticism (2016)	2.0	2.9	7.0	1.6	-0.9	1.4	-0.7	-1.2	1.5	2.6	-2.6	-1.8	1.5
Primary Biliary Cirrhosis	1.2	1.7	4.8	2.2	-1.2	0.1	-0.9	-0.1	0.9	1.2	-1.8	-1.9	0.5
Rheumatoid Arthritis	0.7	0.9	4.1	0.0	2.0	1.2	0.9	0.8	-0.4	-0.3	0.4	1.0	-0.9
Schizophrenia (2014)	0.5	1.1	4.0	2.0	-0.3	1.2	-0.4	-0.3	0.9	1.0	-1.7	-0.1	0.8
Triglycerides	0.3	0.5	1.4	1.0	-0.7	0.4	0.5	-0.4	-1.2	0.0	-0.8	-0.0	0.8
Type 2 Diabetes (T2D) (2012)	5.5	6.4	16.1	-3.1	-2.7	-4.0	-2.2	0.8	-2.1	-2.1	2.4	-2.9	-1.5
Ulcerative Colitis	0.6	0.8	1.8	0.4	-1.0	-0.9	-1.4	-0.5	1.1	0.8	-1.0	-0.8	0.8
Blood Eosinophil Count	0.1	0.5	2.2	-0.1	0.3	-0.9	0.1	-0.4	-1.5	-0.8	0.9	0.8	0.2
Blood Platelet Count	0.4	5.2	10.7	1.5	3.1	2.3	3.3	3.2	-0.5	-0.0	0.0	2.5	-2.7
Blood Red Count	0.1	1.0	3.1	0.5	-1.8	-1.6	-1.1	1.0	-0.3	-0.1	-0.0	-0.9	-1.1
Blood White Count	0.3	2.3	3.9	1.9	1.5	1.2	1.9	2.0	-0.8	-0.2	-0.5	1.9	-1.9
Heel T-Score	0.5	4.2	12.0	1.4	1.3	1.9	3.5	2.4	-1.6	-2.6	1.6	1.2	-1.8
BMI	1.8	10.3	15.9	-4.0	-3.9	-3.5	-3.3	-2.8	-1.7	-3.3	3.3	-3.5	2.0
Height	0.1	2.6	5.2	0.3	1.7	0.5	2.0	2.3	-1.8	-1.3	0.1	2.2	-2.0
Waist Hip Ratio (WHR)	0.9	4.1	11.3	2.7	3.0	2.3	2.4	0.4	0.3	-0.1	-1.5	3.4	0.0
Systolic Blood Pressure	0.7	3.6	6.8	-0.8	-2.6	-0.3	-2.0	-2.4	1.7	2.1	-1.6	-2.1	2.2
Smoking Status	0.3	0.7	1.9	-0.9	0.7	-0.2	0.6	0.8	-0.2	-1.1	1.4	0.3	-1.1
Allergy or Eczema	1.2	3.2	10.2	3.2	1.3	2.4	1.8	0.6	0.4	1.8	-2.0	2.0	-0.1
Cardiovascular Disease	1.3	4.3	11.8	-1.7	-3.4	-3.0	-2.9	-1.7	-0.4	0.1	-0.4	-2.6	1.3
Hypothyroidism (self reported)	0.2	0.5	1.4	0.1	-0.2	0.8	0.6	-0.2	-1.2	1.2	-0.3	0.3	0.9
Respiratory disease	0.3	0.6	2.3	0.6	0.2	1.3	1.5	-0.2	0.7	0.3	-0.5	0.9	-0.0
Type 2 Diabetes (T2D) (2018)	0.5	1.0	3.2	-0.9	-0.3	-0.0	-0.5	-1.8	-0.9	-1.0	0.8	-1.3	1.3
Lung FEV1/FVC ratio	0.4	2.2	9.9	-0.5	1.2	1.1	1.4	1.0	-3.1	-1.5	1.1	1.6	-0.6
Lung FVC	0.3	1.4	5.2	-1.8	-1.0	-2.3	-1.4	0.9	-0.1	-0.4	0.6	-0.9	-0.7
Neuroticism	1.5	3.7	9.0	2.1	-1.3	0.4	-0.9	-1.3	2.8	2.8	-3.0	-1.3	1.2
Chronotype (morning person)	3.3	7.7	32.7	0.3	5.7	1.8	3.3	2.6	-1.1	-1.5	0.6	3.9	-2.0
Hair Pigment	0.0	1.2	2.8	-1.5	-0.8	-1.3	-0.5	-0.1	0.8	-1.4	1.0	-1.7	-0.6
Tanning	0.0	0.3	1.1	-0.8	1.1	0.0	0.2	-0.3	-0.3	0.3	0.2	0.6	0.2
Hand grip strength (left)	0.1	0.3	0.8	0.4	-0.9	-0.3	0.3	0.4	-0.1	0.7	-0.6	0.7	-0.2
Number of treatments/medications taken	0.4	0.8	2.0	0.5	-1.0	0.1	-0.5	-0.4	0.9	1.4	-1.2	-1.1	0.5
Average weekly spirits intake	2.4	2.9	11.0	2.8	0.9	3.3	2.4	0.8	0.3	0.1	-0.5	1.6	-0.2
Sensitivity / hurt feelings	1.0	1.7	7.3	0.0	-1.0	-0.1	-1.2	-1.4	2.7	0.5	-1.1	-1.2	1.5
Frequency of depressed mood in last 2 weeks	0.5	0.6	2.7	0.7	-1.6	-0.5	-0.1	-0.2	0.3	1.1	-0.9	-0.8	0.2
Hearing difficulty/problems: Yes	2.0	3.0	7.7	1.4	-1.6	1.3	-1.2	-2.2	1.1	1.9	-2.8	-1.3	1.9
Relative age of first facial hair	0.3	0.7	2.8	-1.6	0.0	-0.5	-0.3	0.5	1.7	-0.4	0.5	-0.3	-0.5
Other serious medical condition/disability diagnosed by doctor	3.5	4.5	8.7	1.8	-2.9	-0.7	-1.7	-2.0	2.4	2.5	-2.9	-1.5	1.7
Ever used hormone-replacement therapy (HRT)	0.8	1.0	4.5	1.2	1.0	2.1	1.3	0.2	0.7	0.5	-0.4	0.6	-0.1
Ever had hysterectomy (womb removed)	0.7	0.7	4.7	-0.2	0.9	0.1	-0.1	-0.1	2.2	0.9	-0.9	0.5	0.1
Systolic blood pressure, automated reading	0.4	1.2	3.6	-1.1	-1.9	-0.4	-1.4	-0.7	-0.7	-0.3	0.8	-1.8	0.6
Eye problems/disorders: Diabetes related eye disease	2.7	3.0	7.7	-0.9	-2.2	-0.2	-1.5	-2.5	0.6	0.7	-1.3	-2.4	2.8
Angina	0.8	1.0	2.9	0.4	-0.6	-0.5	-1.0	-1.7	-0.1	0.7	-1.5	-0.8	1.6
Medication for hormone replacement therapy	2.5	2.8	7.0	2.1	1.8	2.6	1.6	0.4	1.0	2.0	-2.1	1.0	0.3
Vitamin and mineral supplements	0.4	0.5	1.1	-0.1	-1.0	-1.0	-0.6	-1.1	0.2	1.0	-0.8	-0.4	0.2
Supplements: Zinc	0.5	0.5	1.2	-0.8	0.2	0.8	-0.3	-1.1	0.5	-1.0	0.6	0.4	1.0
Medication: Co-codamol	0.2	0.3	1.1	-0.8	0.0	-0.6	-0.6	-0.2	0.3	0.2	-0.1	-1.0	0.0
Medication: Metformin	1.1	1.5	4.6	-1.2	-1.1	-0.7	-0.6	-0.9	-2.2	-1.2	0.8	-1.8	0.9
Diabetes (father)	1.2	1.4	4.5	-1.6	-0.5	-1.6	-0.9	-0.2	-0.0	-2.1	1.5	-1.1	0.1
Diabetes (mother)	1.2	1.6	3.7	-0.1	1.9	0.7	1.1	1.9	-1.2	-1.1	0.6	0.5	-1.9
Severe depression (siblings)	0.4	0.5	1.9	-1.0	-0.2	-1.1	0.0	-0.1	0.1	1.4	-0.3	-0.0	-0.7
Pack years adult smoking proportion	1.8	2.7	5.8	0.4	2.1	1.6	2.2	1.8	-1.5	-0.8	1.1	2.4	-1.4
Impedance of leg (right)	1.3	6.3	13.2	3.4	2.3	1.9	2.0	1.9	1.5	3.6	-3.1	2.7	-1.6
Leg fat-free mass (left)	1.8	9.5	15.5	-3.9	-3.3	-3.7	-2.7	-1.2	-3.2	-3.8	3.4	-3.1	0.7
Trunk fat percentage	1.3	5.4	10.7	-2.5	-2.9	-3.3	-2.3	-1.1	-2.2	-2.6	2.1	-2.5	0.6
Hand grip strength (right)	0.1	0.3	0.7	-0.3	-0.6	-0.8	0.2	0.5	-0.6	0.1	0.3	0.4	-0.7
Townsend deprivation index at recruitment	2.7	3.8	8.5	-2.2	0.8	-0.8	1.2	1.8	-2.5	-2.1	2.9	1.9	-2.0
Current tobacco smoking	0.6	1.0	2.4	-0.2	0.6	-0.0	1.5	1.1	-1.3	-0.5	1.0	1.5	-1.1
Average weekly fortified wine intake	0.6	0.7	2.7	1.0	0.8	0.8	1.1	0.4	-0.8	-0.5	0.4	1.7	0.0
Maternal smoking around birth	0.9	1.3	4.5	0.6	-1.0	0.7	-0.8	-1.8	-1.1	0.2	-1.1	-0.9	2.1
Fed-up feelings	0.5	0.9	2.4	-1.2	-1.0	-1.2	-1.6	-0.6	0.3	0.9	-0.6	-0.8	0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.2	0.7	0.9	-0.5	0.1	0.6	0.2	-0.5	-0.1	0.0	-0.0	-0.0
Relative age voice broke	0.5	0.7	5.5	-0.3	-0.0	0.1	-0.3	0.3	2.3	0.2	-0.1	-1.2	-0.0
Taking other prescription medications	0.8	1.2	5.2	0.4	-0.2	-0.2	-0.5	-1.2	0.3	1.9	-2.3	-0.1	1.1
Age when periods started (menarche)	0.9	2.2	5.2	0.4	-0.5	-1.2	-1.9	0.0	1.8	2.3	-2.0	-1.9	-0.0
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	1.8	-1.3	-0.9	-0.9	-0.4	0.8	-0.3	-0.5	0.6	-1.1	-0.5
Heel bone mineral density (BMD) T-score, automated (left)	1.2	2.8	7.4	0.3	1.5	1.4	1.9	1.7	-2.7	-2.0	1.6	1.1	-1.4
Tinnitus: Yes, but not now, but have in the past	2.9	3.1	5.9	0.9	2.3	1.5	2.2	2.3	1.2	-0.1	0.5	2.4	-2.3
Qualifications: CSEs or equivalent	1.5	2.0	4.1	-0.0	-0.4	-0.8	-2.0	-1.8	2.0	1.6	-1.8	-0.7	1.2
Serious illness, injury or assault to yourself	0.6	0.7	2.7	1.6	-0.1	0.3	0.1	-0.5	-0.5	0.5	-1.6	-0.7	0.3
High blood pressure	0.5	1.4	3.4	-1.3	-1.9	-1.3	-1.1	-0.6	-0.7	-1.6	1.2	-0.9	0.6
Hayfever, allergic rhinitis or eczema	1.2	2.6	8.1	2.8	0.4	2.4	1.5	-0.4	1.1	1.6	-1.9	1.3	0.7
Multivitamins +/- minerals	0.6	0.7	1.8	-0.1	1.1	1.4	0.9	1.0	-0.5	-1.1	0.8	0.7	-0.1
Stomach or abdominal pain in last month	2.2	2.7	7.3	1.7	2.6	2.7	1.9	0.5	0.7	0.7	-0.0	2.4	-0.2
Supplements: Glucosamine	0.6	0.8	3.3	-1.8	-0.9	-0.3	-1.0	-0.7	-0.4	-0.4	0.7	-0.9	0.7
Diverticular disease/diverticulitis (self-reported)	2.1	2.4	6.7	1.6	1.6	2.6	1.1	0.7	1.8	1.9	-1.3	1.6	-0.1
Medication: Atenolol	0.5	0.7	1.9	-0.4	-1.4	-0.4	-0.6	-0.8	-0.8	-1.1	0.5	-0.8	0.8
Medication: Levothyroxine sodium	0.3	0.5	1.4	0.6	-0.8	0.2	-0.0	-0.5	-0.7	1.2	-1.1	-0.2	0.7
Sitting height	0.2	1.2	4.6	-1.0	-0.5	-1.6	-0.4	0.8	-2.1	-1.2	0.9	0.4	-0.7
Chronic bronchitis/emphysema (father)	0.5	0.6	2.1	-0.1	-0.6	-0.4	-1.0	-1.4	0.6	-0.3	-0.3	-0.7	1.3
High blood pressure (mother)	0.3	0.4	1.8	0.2	0.4	1.3	1.0	-0.1	-0.2	-0.4	-0.0	0.5	0.3
Body mass index (BMI)	2.5	10.7	16.7	-4.1	-3.8	-3.6	-3.2	-2.0	-2.3	-3.9	3.5	-3.7	1.5
Impedance of leg (left)	1.7	8.2	17.4	4.2	3.0	2.5	2.7	2.1	1.4	3.5	-3.0	3.6	-1.6
Leg predicted mass (left)	1.8	9.5	16.0	-4.0	-3.2	-3.6	-2.5	-1.1	-3.3	-4.0	3.5	-2.9	0.6
Trunk fat mass	1.8	7.9	13.7	-3.2	-3.2	-3.7	-2.6	-1.1	-2.8	-3.4	2.9	-2.8	0.6
Waist circumference	1.4	5.2	12.2	-2.3	-2.5	-3.0	-1.9	-0.9	-2.1	-3.5	2.6	-2.0	0.5
Number of incorrect matches in round	0.5	0.8	4.3	0.3	0.4	0.9	0.5	-0.3	2.1	0.6	-0.6	1.3	0.2
Past tobacco smoking	0.2	0.4	1.1	-0.0	0.9	-0.6	0.2	0.4	0.1	1.0	-0.8	0.8	-0.5
Alcohol usually taken with meals	0.3	0.4	1.1	0.5	1.1	0.8	1.0	-0.5	-0.1	0.3	0.7	0.6	0.5
Nervous feelings	2.8	5.3	14.2	1.3	-2.1	-0.1	-1.6	-2.1	3.8	2.8	-3.3	-1.3	2.2
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	1.2	1.1	-0.5	0.8	0.4	-0.4	-0.5	0.9	-0.7	-0.2	0.9
Hearing difficulty/problems with background noise	1.5	2.3	6.8	2.6	-0.4	2.4	1.1	-0.4	0.4	1.8	-2.3	-0.1	0.7
Hair/balding pattern: Pattern 2	0.5	0.6	1.7	0.3	0.2	1.3	1.2	1.0	0.5	0.2	0.4	-0.6	-1.0
Had menopause	0.4	0.5	1.3	-0.9	0.3	0.2	0.6	0.9	-0.1	-0.6	1.0	-0.2	-1.1
Had other major operations	1.3	1.6	6.6	1.7	0.3	0.2	0.2	0.3	1.0	2.6	-1.9	0.9	-0.6
Forced vital capacity (FVC)	0.1	0.5	1.4	0.6	-0.6	-0.8	-0.8	0.3	-0.3	1.2	-1.1	-0.2	0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.8	1.7	5.3	0.7	1.0	1.2	1.7	1.5	-2.3	-1.3	0.8	0.7	-1.3
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	1.5	0.7	-0.8	-1.2	-0.6	0.5	0.7	0.4	-0.5	-0.1	-1.1
Qualifications: None of the above	0.3	0.7	2.8	-1.7	-0.8	-0.9	-0.8	-0.6	-0.5	-0.7	0.5	-0.5	0.3
Financial difficulties in last 2 years	1.1	1.4	3.0	0.2	1.2	0.0	1.6	1.7	-0.6	-1.4	1.0	1.1	-1.7
Mouth/teeth dental problems	0.5	0.8	3.2	1.8	0.8	0.3	0.5	0.9	0.4	0.3	-0.3	1.1	-1.1
Heart attack	0.6	0.7	2.8	-0.3	-0.4	-0.6	-1.2	-1.7	-0.4	-0.1	-0.1	-0.8	1.3
Allergy	1.1	2.4	6.8	-2.5	1.0	-1.7	-0.8	0.9	-0.9	-2.0	2.6	0.1	-1.0
Pain all over the body in last month	2.1	2.3	6.4	0.1	-2.5	-1.2	-1.7	-1.4	-1.0	1.9	-1.5	-1.2	1.4
Diabetes (self-reported)	1.4	2.1	7.0	-0.5	-1.6	-0.5	-1.7	-2.1	-0.0	-0.3	-0.4	-2.6	1.9
Hayfever/allergic rhinitis (self-reported)	2.5	3.4	9.1	2.6	0.7	2.1	1.5	-0.3	2.0	3.0	-2.4	0.7	0.8
Medication: Ramipril	0.3	0.3	1.4	0.3	1.2	0.5	0.2	-0.7	0.1	-0.2	-0.4	0.7	0.8
Medication: Simvastatin	0.4	0.6	2.3	-0.9	-0.2	0.4	0.3	-1.1	-1.5	-1.0	0.3	0.1	0.9
Fluid intelligence score	0.8	1.7	5.9	-1.4	-0.6	-2.4	-1.4	0.1	-2.0	-0.1	1.6	-0.1	-0.5
Illnesses of siblings	1.5	2.1	3.0	0.8	-1.7	-1.1	-1.7	-1.6	1.3	1.6	-1.5	-1.4	1.5
Neuroticism score	2.4	5.0	12.0	1.8	-2.0	0.4	-1.6	-1.8	3.5	2.9	-3.2	-1.7	1.9
Weight	2.2	11.0	18.5	-4.3	-3.6	-4.2	-3.0	-1.1	-3.2	-4.1	3.6	-3.2	0.6
Impedance of arm (right)	0.6	3.0	9.3	2.2	1.3	0.6	0.7	1.2	1.1	3.0	-3.0	1.2	-0.9
Arm fat percentage (right)	2.0	8.0	13.1	-2.9	-3.6	-3.5	-3.2	-2.0	-2.0	-2.8	2.3	-3.6	1.5
Trunk fat-free mass	1.1	6.3	12.1	-3.5	-2.3	-3.0	-1.7	-0.3	-3.0	-3.2	3.3	-1.8	-0.0
Hip circumference	2.4	10.5	18.7	-3.7	-4.3	-4.3	-3.6	-1.9	-2.3	-3.1	2.9	-3.6	1.3
Time employed in main current job	0.7	0.8	1.8	1.4	1.2	1.1	0.7	0.2	-1.2	-0.3	-0.7	0.8	0.0
Alcohol intake versus 10 years previously	1.1	1.6	4.1	-0.6	0.9	-0.3	1.0	2.0	0.4	-1.5	1.7	0.8	-2.0
Father’s age at death	0.8	1.1	3.8	-0.7	1.0	0.6	0.9	1.9	-0.4	-0.4	0.6	-0.2	-1.9
Worrier / anxious feelings	1.7	3.2	7.7	2.3	-1.8	0.2	-0.7	-1.3	1.8	2.5	-2.8	-1.8	1.1
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	1.6	1.3	-0.7	-0.0	0.5	1.0	-0.1	0.7	-0.3	0.7	-0.8
Falls in the last year	0.2	0.3	1.1	0.7	1.0	0.3	-0.2	0.1	0.1	0.1	-0.9	-0.1	-0.1
Hair/balding pattern: Pattern 3	0.8	1.1	4.6	2.1	0.5	1.8	0.9	-0.7	0.1	0.5	-0.6	0.8	0.8
Number of live births	1.3	1.8	8.1	-0.7	-2.0	0.3	-1.2	-0.7	0.2	1.5	-0.6	-2.8	0.9
Forced expiratory volume in 1-second (FEV1)	0.1	0.4	1.1	0.1	-0.7	-0.5	-1.1	-0.0	-0.7	0.8	-0.7	-0.3	0.7
Pulse rate	1.6	2.8	6.8	-1.9	-1.9	-2.6	-2.2	0.2	-0.4	-1.0	1.7	-2.0	-0.6
Happiness	2.9	3.5	10.6	3.3	-1.3	2.0	0.3	-1.3	1.7	2.5	-2.1	-0.1	1.8
Noisy workplace	0.6	0.7	3.1	-1.8	0.5	-0.5	-0.3	-0.5	-0.9	-1.3	0.7	-0.0	0.2
Qualifications: A levels/AS levels or equivalent	1.0	2.2	5.9	1.4	-0.7	0.1	-1.1	-1.1	2.4	2.1	-2.2	-0.8	1.0
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	4.4	0.2	0.2	-0.5	0.6	-0.2	-2.1	-1.3	1.0	0.7	-0.1
Mouth/teeth dental problems: Dentures	1.6	2.6	6.9	-2.5	-2.1	-1.6	-1.6	-1.4	-0.6	-0.2	-0.1	-2.6	1.4
Asthma	0.4	0.8	2.4	0.4	-0.8	0.7	0.4	-0.8	1.5	1.2	-1.2	-0.5	0.6
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.7	2.3	1.2	1.5	0.6	0.7	0.2	0.6	0.3	0.2	1.5	0.1
Medication: Cholesterol lowering	1.2	1.8	3.8	-0.7	-1.9	-1.6	-1.9	-1.4	-0.3	-0.3	-0.9	-1.8	1.1
Depression (self-reported)	3.7	4.4	9.8	1.1	-3.1	-1.5	-2.3	-1.1	1.9	2.4	-2.9	-2.3	1.1
Medication: Lansoprazole	0.5	0.6	2.0	0.7	-0.7	-0.3	-0.4	-0.0	0.9	1.4	-1.4	-0.0	-0.2
Prospective memory result	2.9	3.6	7.5	1.2	2.7	2.7	2.6	1.5	-1.2	-1.4	1.2	2.4	-0.8
Lung cancer (father)	0.5	0.6	2.2	-0.0	1.5	1.3	0.6	-0.3	0.2	-0.2	-0.7	0.8	0.8
Illnesses of mother	0.4	0.5	2.2	-0.4	1.1	0.3	0.3	-0.1	1.5	0.5	0.0	0.8	-0.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.6	1.9	-1.0	-0.2	-0.9	-0.5	1.4	-1.1	0.0	0.2	0.4	-0.7
Pulse wave Arterial Stiffness index	1.5	1.8	5.0	-2.2	-0.6	-2.2	-0.7	0.4	-1.1	-1.5	1.5	-0.6	-0.9
Impedance of arm (left)	0.7	3.1	6.7	2.0	1.9	0.7	1.2	1.3	0.9	2.5	-2.6	2.0	-1.2
Arm fat mass (right)	2.4	9.7	15.3	-3.7	-3.7	-3.9	-3.1	-1.7	-2.6	-3.6	3.1	-3.4	1.1
Trunk predicted mass	1.1	6.2	12.0	-3.5	-2.3	-2.9	-1.6	-0.3	-3.0	-3.1	3.3	-1.8	-0.0
Standing height	0.2	1.7	4.5	-1.0	-0.2	-1.8	0.1	1.8	-2.1	-0.8	0.6	0.7	-1.8
Length of working week for main job	1.2	1.4	3.6	1.4	1.9	0.9	1.2	1.0	0.8	0.2	-0.5	1.8	-0.9
Exposure to tobacco smoke at home	0.2	0.2	0.9	-0.5	0.8	-0.3	0.2	0.1	-0.2	-0.2	0.9	0.4	-0.4
Breastfed as a baby	1.1	1.3	5.9	-0.8	-1.3	-2.4	-1.0	1.0	-0.0	0.8	0.3	-0.6	-1.3
Tense / ‘highly strung’	3.2	5.4	12.0	3.1	-0.3	2.0	-0.1	-1.4	3.2	3.4	-3.5	0.2	2.0
Seen doctor (GP) for nerves, anxiety, tension or depression	2.6	4.0	13.8	3.4	-0.9	0.9	-0.2	-0.4	0.8	3.7	-3.5	0.2	0.5
Hair/balding pattern: Pattern 4	1.1	2.6	6.8	-0.8	-2.1	-2.6	-2.5	-1.7	-0.0	0.4	-0.8	-1.4	1.4
Birth weight of first child	1.3	2.3	5.0	-1.7	0.3	-1.4	0.7	1.6	-1.2	-2.1	2.2	0.8	-1.8
Peak expiratory flow (PEF)	0.3	0.8	1.9	0.5	-0.9	-0.1	-1.2	-0.8	-0.7	-0.2	-0.2	-1.4	1.4
Pulse wave reflection index	0.4	0.5	2.1	-0.4	1.5	0.2	0.6	0.8	-0.5	-0.5	0.1	1.1	-0.7
Ever highly irritable/argumentative for 2 days	0.5	0.5	1.2	0.9	-0.6	0.2	-0.3	-1.1	0.8	0.6	-1.1	-0.4	0.8
Loud music exposure frequency	0.4	0.4	1.0	1.0	0.5	0.1	0.3	0.8	-0.8	-0.7	-0.4	0.7	-0.6
Qualifications: O levels/GCSEs or equivalent	2.3	3.7	7.5	1.6	-2.1	0.0	-1.6	-2.0	2.0	1.7	-2.7	-2.2	2.0
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	1.5	-1.2	0.6	0.1	0.1	0.1	-0.0	-0.4	0.4	0.7	-0.1
Blood clot in the leg (DVT)	0.3	0.3	1.4	1.2	0.1	0.1	0.1	-0.6	-0.7	0.2	-0.6	-0.7	0.6
Medication: Paracetamol	1.5	2.5	6.7	2.6	0.8	2.5	1.2	-0.2	2.2	1.5	-1.4	0.9	0.6
Headache pain in last month	1.3	2.2	6.4	2.5	0.7	1.9	1.7	1.2	1.0	1.3	-1.9	0.8	-0.6
Medication for cholesterol, blood pressure or diabetes	0.7	1.1	2.1	1.2	1.2	1.4	1.3	0.9	1.0	1.1	-0.2	0.9	-0.7
Glaucoma (self-reported)	1.1	1.3	5.7	1.6	0.5	2.4	0.6	-0.5	0.7	1.3	-1.0	-0.5	1.0
Gout (self-reported)	0.8	1.1	2.0	0.2	-1.3	-0.9	-1.2	-0.7	-1.1	0.9	-1.2	-1.4	0.7
Hypothyroidism/myxoedema (self-reported)	0.2	0.3	1.3	0.4	-0.1	0.6	0.7	0.4	-0.7	1.1	-0.7	-0.0	0.1
Medication: Amlodipine	0.7	1.0	3.2	-0.8	-0.7	-1.5	-1.8	-1.4	0.3	0.5	0.2	-0.6	1.1
Medication: Ventolin 100micrograms inhaler	0.3	0.4	1.0	0.3	-1.0	-0.7	-0.5	-0.4	0.9	0.6	-0.5	-0.9	0.2
Birth weight	0.7	1.6	5.3	-1.4	-1.2	-2.3	-1.5	0.4	-0.9	-0.9	1.3	-1.0	-0.7
Chronic bronchitis/emphysema (mother)	0.7	0.8	2.8	1.0	0.0	0.7	-0.6	-1.4	-0.1	0.3	-0.8	-0.7	1.7
High blood pressure (siblings)	0.8	1.2	2.2	-0.2	1.1	0.8	1.5	1.4	-0.2	-1.1	1.3	1.2	-1.3
Forced vital capacity (FVC), Best measure	0.1	0.5	1.4	-0.5	-0.6	-1.2	-0.8	0.9	-0.8	0.6	-0.2	0.1	-0.3
Body fat percentage	1.5	6.0	9.7	-2.6	-3.1	-3.1	-2.5	-1.4	-2.0	-2.7	2.3	-2.8	0.9
Leg fat percentage (right)	2.0	7.2	11.0	-3.1	-3.3	-3.1	-2.5	-1.1	-2.3	-3.0	3.1	-3.2	0.7
Arm fat-free mass (right)	1.0	5.4	11.6	-3.0	-2.0	-2.5	-1.2	-0.3	-2.8	-3.4	3.4	-1.3	-0.1
Exposure to tobacco smoke outside home	1.4	1.9	7.7	-0.6	0.2	-0.7	0.7	0.1	-1.9	-2.4	2.8	-0.2	-0.4
Comparative body size at age 10	1.0	2.9	7.9	-2.1	-2.8	-2.5	-1.8	-1.0	0.3	-0.8	1.2	-1.9	0.7
Number of full brothers	0.6	0.7	2.7	-0.4	-0.8	-0.2	-0.7	-0.7	1.6	0.7	-0.8	-1.0	0.7
Worry too long after embarrassment	2.9	4.9	8.8	-0.6	-2.7	-0.8	-2.4	-2.7	3.0	2.0	-1.7	-2.4	2.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.7	2.6	1.3	0.0	0.4	0.1	-0.2	-0.7	1.6	-0.9	0.8	0.4
Wheeze or whistling in the chest in last year	0.8	1.5	3.1	1.4	-1.6	0.6	-0.4	-0.7	1.5	1.6	-1.7	-1.0	0.6
Number of children fathered	0.6	0.7	1.6	1.0	1.3	-0.1	-0.1	1.2	-0.9	-0.3	-0.3	0.4	-1.1
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.4	2.2	-0.8	-0.2	-0.3	-0.7	-0.2	1.5	-0.2	-0.3	-0.8	0.3
Age at first live birth	0.6	1.0	2.8	0.2	-1.7	-1.7	-1.5	-0.3	0.8	-0.1	-0.3	-1.1	0.1
Pulse wave peak to peak time	1.3	1.5	4.7	2.2	0.6	2.0	0.6	-0.3	0.7	1.5	-1.4	0.7	0.8
Health satisfaction	0.7	0.9	2.8	1.6	-0.1	1.1	-0.3	-1.4	0.5	-0.1	-0.1	-0.1	1.7
Shortness of breath walking on level ground	0.7	0.8	3.3	0.3	-0.5	-0.8	-1.8	-0.4	-0.4	0.9	-1.6	-0.5	0.5
Qualifications: College or University degree	0.1	0.2	1.2	1.1	0.1	0.4	0.3	0.4	0.6	0.5	-0.4	0.0	-0.4
Eye problems/disorders: None of the above	0.4	0.5	1.8	-1.3	-0.5	-0.9	-0.6	0.2	0.8	-0.3	0.4	0.3	-0.6
Mouth/teeth dental problems: Loose teeth	2.7	3.2	8.1	-2.8	-1.4	-1.7	-1.3	-1.1	-1.7	-1.5	1.9	-2.7	0.7
Emphysema/chronic bronchitis	0.4	0.4	2.0	0.4	-0.4	-0.0	-0.2	-0.6	1.4	0.6	-0.9	0.2	0.5
Medication for pain relief, constipation, heartburn	1.6	2.8	6.9	-2.4	-2.1	-2.6	-1.5	0.5	-0.7	-1.1	1.0	-2.2	-0.8
Neck or shoulder pain in last month	2.0	2.8	9.4	1.2	3.1	2.5	1.8	-0.0	1.4	0.8	-0.6	2.2	0.0
Medication: Blood pressure	0.2	0.4	2.4	-0.0	-1.6	-0.8	-0.7	0.0	-0.3	-0.3	-0.2	-0.6	0.2
Angina (self-reported)	0.6	0.8	2.0	0.2	-0.7	-0.8	-1.0	-1.4	-0.3	0.5	-1.3	-0.8	1.3
Migraine (self-reported)	0.5	0.7	1.6	-0.2	-0.9	-1.3	-1.0	-1.1	-0.2	0.4	-0.0	-1.1	0.9
Medication: Ibuprofen	0.6	0.7	2.2	1.1	1.5	-0.0	0.6	0.6	0.3	-0.5	0.7	1.4	-0.4
Medication: Allopurinol	0.4	0.6	1.4	-1.2	-1.0	-0.9	-0.6	-0.2	-0.8	-0.4	-0.3	-1.2	-0.2
Medication: Omeprazole	2.6	3.1	6.3	2.4	2.5	1.9	1.8	0.6	1.2	1.7	-1.4	2.2	-0.8
Medication: Seretide 50 evohaler	0.6	0.7	1.9	-0.6	1.0	0.5	1.4	1.1	-0.7	-0.5	0.6	0.3	-1.2
Mean time to correctly identify matches	0.9	1.7	5.8	-0.9	0.6	0.6	1.1	0.9	-0.5	-2.1	2.4	1.5	-0.7
Heart disease (mother)	0.3	0.4	1.3	0.8	-0.4	0.1	0.6	0.7	-1.2	-0.5	0.2	0.4	-0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.3	0.9	0.6	-1.0	0.3	-0.0	0.6	0.1	0.4	-0.8	-0.3	-0.3
Whole body fat mass	2.1	8.6	13.7	-3.3	-3.4	-3.4	-2.6	-1.4	-3.0	-3.7	3.2	-3.0	0.9
Leg fat mass (right)	2.8	10.8	16.4	-3.8	-3.8	-3.9	-3.0	-1.4	-3.2	-4.0	3.8	-3.5	0.8
Arm predicted mass (right)	1.1	5.4	11.2	-3.0	-2.0	-2.6	-1.6	-0.5	-2.7	-3.2	3.4	-1.4	0.2
Pulse rate, automated reading	2.4	7.7	20.1	-2.5	-3.8	-4.2	-4.5	-1.0	-0.1	-0.6	1.6	-3.8	0.4
Alcohol intake frequency.	0.2	0.4	1.4	-1.2	0.3	0.2	0.1	0.7	-0.4	-1.0	0.6	0.5	-0.2
Comparative height size at age 10	1.1	6.0	11.6	-0.8	2.1	0.4	2.8	3.2	-3.2	-2.0	1.8	3.4	-2.8
Number of full sisters	1.0	1.3	3.4	-0.6	-1.1	-0.8	-1.5	-1.7	1.2	0.2	-0.2	-0.6	1.8
Suffer from ‘nerves’	0.8	1.3	3.1	0.2	-0.8	0.2	-0.8	-1.8	1.3	1.2	-1.0	-1.1	1.7
Overall health rating	0.2	0.5	1.9	1.0	-1.4	0.3	-0.2	-0.8	-0.0	0.5	-0.6	-0.5	0.8
Chest pain or discomfort	0.4	0.6	1.9	1.4	-0.2	-1.0	-0.5	0.3	-0.3	1.1	-0.9	0.5	-0.6
Had major operations	0.8	0.9	4.4	2.1	0.9	0.4	0.4	-0.3	-0.9	1.0	-1.0	0.6	-0.1
Age at last live birth	1.0	1.4	8.8	0.4	-3.0	-1.0	-0.5	-0.4	-0.3	-0.5	-0.1	-1.8	0.4
Family relationship satisfaction	0.7	0.9	2.5	1.0	0.5	1.3	1.6	0.9	0.8	-0.3	0.5	1.2	-0.3
Leg pain on walking	0.8	1.0	5.0	2.2	0.2	1.5	1.4	0.0	-0.1	0.9	-0.7	-0.0	0.2
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.2	3.9	-1.7	0.1	-2.0	-1.2	0.2	-1.4	-0.8	0.9	-0.2	-0.6
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.4	-0.2	0.7	-0.3	0.3	0.0	-0.0	-0.4	-0.1	-0.3	-0.3
Illness, injury, bereavement, stress in last 2 years	1.3	1.6	6.1	0.3	0.2	1.9	-0.3	-0.1	2.5	2.2	-0.9	0.5	0.8
Medication: Aspirin	0.6	0.8	4.0	0.3	0.7	0.6	0.6	-0.1	-2.0	0.2	-0.3	1.5	-0.0
Supplements: Vitamin C	0.3	0.4	1.2	-0.9	-0.0	-0.4	-0.0	0.2	0.3	-0.7	1.1	-0.9	-0.3
Knee pain experienced in last month	0.1	0.2	0.6	0.2	-0.3	-0.5	-0.2	-0.1	0.7	0.7	-0.3	-0.6	-0.2
Hypertension (Self-reported)	0.4	1.1	3.0	-1.1	-1.7	-1.1	-0.9	-0.5	-0.5	-1.5	1.1	-0.7	0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	1.2	-0.1	0.5	-0.4	-0.9	-0.7	-0.0	1.1	-0.6	0.4	0.3
Illnesses of father: Heart disease	0.3	0.4	1.4	0.9	-1.2	-0.4	-0.4	-0.4	-0.9	0.2	-0.2	-0.3	0.4
Illnesses of siblings: Diabetes	0.2	0.3	0.9	-0.9	-0.1	-0.1	-0.5	-0.1	-0.3	-0.8	0.0	-1.0	0.3
Smoking status: Previous	0.4	0.7	2.1	-0.0	-0.5	0.8	-0.8	-1.3	0.5	-0.1	-0.1	-1.1	1.4
Forced expiratory volume in 1-second (FEV1), predicted	0.9	1.8	6.2	-0.5	2.2	-1.1	0.4	1.7	-0.6	0.5	0.2	2.5	-1.5
Whole body fat-free mass	1.3	7.5	13.2	-3.6	-2.7	-3.2	-2.0	-0.7	-3.2	-3.5	3.5	-2.2	0.3
Leg fat-free mass (right)	1.6	8.3	14.7	-3.7	-2.9	-3.3	-2.4	-1.2	-3.1	-3.8	3.4	-2.6	0.8
Arm fat percentage (left)	1.8	7.2	10.3	-3.0	-3.1	-3.2	-2.7	-1.8	-2.2	-3.1	2.7	-3.0	1.3
Average weekly red wine intake	0.5	0.8	4.0	2.0	0.7	0.8	0.9	0.7	-0.6	0.4	-0.4	1.0	-0.2
Handedness (chirality/laterality): Left-handed	0.8	1.0	5.0	0.8	-2.2	0.5	-0.6	-0.2	-0.2	0.2	-0.4	-1.4	1.2
Mood swings	1.1	1.9	6.8	0.9	-0.9	-0.2	-1.0	-0.3	1.9	2.6	-2.1	-1.0	0.4
Loneliness, isolation	0.3	0.4	1.0	1.0	-0.8	0.7	0.5	0.2	1.0	0.5	-0.5	-0.4	0.4
Long-standing illness, disability or infirmity	0.3	0.4	1.7	-0.5	-1.3	-0.4	-0.3	-0.3	0.3	0.1	-0.6	-1.1	-0.3
Ever had bowel cancer screening	0.2	0.2	0.6	-0.5	0.8	0.8	0.4	-0.2	-0.4	0.6	-0.1	-0.1	-0.1
Diabetes diagnosed by doctor	0.9	1.5	4.4	-0.2	-0.9	-0.0	-1.0	-2.1	-0.5	-0.6	-0.2	-2.1	1.9
Ever had stillbirth, spontaneous miscarriage or termination	0.9	1.0	3.6	-1.2	0.3	-0.9	0.4	1.5	-0.2	0.7	-0.2	1.1	-1.9
Friendships satisfaction	0.4	0.5	1.8	0.5	-0.7	1.3	-0.2	-0.7	0.0	-0.2	0.2	-0.0	1.3
Qualifications: nursing, teaching	0.4	0.6	1.9	0.9	-0.6	-0.5	-0.4	0.4	0.0	1.4	-1.3	-0.7	-0.6
Commuting to job workplace: Walk	0.2	0.3	0.8	0.5	-0.9	-0.0	0.1	0.8	0.5	0.3	0.0	0.1	-0.6
Eye problems/disorders: Cataract	1.1	1.3	2.9	1.7	-0.4	0.6	-0.4	-1.0	0.7	1.6	-1.6	-1.1	1.2
Mouth/teeth dental problems: Mouth ulcers	0.1	0.1	0.5	0.2	0.0	0.6	0.7	0.3	0.3	-0.2	-0.1	-0.1	-0.0
Medication for cholesterol	0.2	0.3	1.0	-0.0	-0.4	-0.1	0.0	0.5	-1.0	-0.9	0.8	0.1	-0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	1.2	0.0	-1.1	0.3	-0.9	-0.7	0.4	-0.1	-0.7	-0.8	0.9
Back pain experienced in last month	0.6	0.9	2.8	1.2	1.1	1.7	1.2	0.5	0.6	0.4	-0.4	1.0	-0.0
Mineral and other dietary supplements	0.2	0.3	1.0	0.8	-0.4	-0.1	0.2	-0.1	0.3	0.7	-1.0	0.1	-0.2
Breast cancer (self-reported)	0.3	0.3	0.8	0.7	0.7	-0.4	0.1	0.6	-0.4	0.4	-0.4	0.8	-0.9
Asthma (self-reported)	0.3	0.6	2.0	0.2	-0.8	0.6	0.4	-0.7	1.4	0.9	-1.0	-0.4	0.5
Osteoporosis (self-reported)	0.6	0.8	2.9	-1.7	-0.9	-1.0	0.1	0.2	0.5	-0.7	0.8	-1.1	-0.6
Osteoarthritis (self-reported)	1.1	1.4	4.5	0.3	-2.1	-0.4	-1.2	-1.6	0.8	1.0	-0.8	-1.3	1.0
Medication: Aspirin	0.6	0.7	5.1	0.3	0.8	0.2	0.3	-0.0	-2.3	0.0	-0.1	1.2	-0.1
Medication: Gliclazide	0.7	0.8	4.2	2.0	-0.4	0.4	-0.2	-0.7	0.5	1.2	-0.6	-0.4	0.9
Illnesses of father: None of the above (group 1)	0.7	0.9	2.5	-0.5	1.6	0.8	0.9	1.4	0.2	0.3	-0.2	1.0	-1.3
Smoking status: Current	1.0	1.6	3.1	-0.2	0.7	-0.1	1.7	1.7	-1.2	-0.9	1.3	1.5	-1.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.0	2.9	0.3	0.1	0.7	1.4	1.7	-1.2	-0.9	0.8	0.8	-1.0
Whole body water mass	1.3	7.1	12.5	-3.5	-2.7	-3.0	-1.9	-0.7	-3.1	-3.5	3.4	-2.2	0.4
Leg predicted mass (right)	1.6	8.3	14.5	-3.6	-2.9	-3.3	-2.4	-1.3	-3.1	-3.8	3.4	-2.6	0.9
Arm fat mass (left)	2.3	9.5	13.9	-3.7	-3.6	-3.7	-3.1	-1.8	-2.6	-3.7	3.1	-3.3	1.3
Number of self-reported non-cancer illnesses	1.6	2.8	6.1	0.3	-2.0	-0.3	-1.1	-2.5	0.7	2.4	-2.1	-1.5	1.9
Average weekly champagne plus white wine intake	0.7	0.9	3.5	-0.6	0.1	0.0	-1.3	-1.9	-0.6	1.0	-0.5	-0.2	1.4
Miserableness	0.9	1.5	3.8	0.7	-1.4	-0.1	-1.2	-0.8	0.8	2.0	-1.7	-1.6	0.7
Guilty feelings	0.6	0.9	4.4	-0.1	-2.1	-0.7	-0.5	-0.2	-0.4	-1.3	1.0	-1.1	0.2
Wears glasses or contact lenses	0.3	0.3	1.5	1.2	0.4	0.9	0.2	-0.3	-0.1	0.7	-0.4	0.5	-0.1
Ever taken oral contraceptive pill	0.5	0.5	1.6	0.8	0.6	1.2	0.8	-0.4	-0.5	0.4	-0.5	0.8	0.7
Hearing aid user	1.1	1.3	4.4	0.4	-0.4	0.0	-1.4	-1.0	1.4	1.6	-2.1	-0.1	0.8
Mother’s age at death	0.2	0.3	1.6	1.3	0.4	0.2	-0.2	-0.3	-0.3	0.3	-0.8	-0.5	0.2
Financial situation satisfaction	2.5	3.1	7.8	2.8	2.4	1.8	2.4	1.0	0.6	0.3	-0.4	2.6	-0.5
Tinnitus: Yes, now most or all of the time	1.5	1.8	4.8	2.0	1.6	2.2	1.3	-0.0	0.5	1.2	-1.5	1.0	0.0
Commuting to job workplace: Public transport	0.7	0.9	5.3	-0.6	-0.3	-0.1	0.0	0.5	-2.3	-0.9	1.0	0.8	-0.2
Eye problems/disorders: Glaucoma	0.3	0.4	2.3	0.5	0.4	1.5	0.4	-0.1	-0.4	0.3	0.1	-0.5	0.6
Medication: Blood pressure	0.4	0.7	1.9	-1.3	-0.1	-1.1	-0.4	-0.3	0.1	-1.4	1.3	-0.4	-0.0
Pain type(s) experienced in last month: Hip pain	0.7	0.9	2.9	0.7	-1.0	0.1	-0.6	-1.7	1.0	1.2	-0.7	-0.8	1.1
Supplements: Fish oil (including cod liver oil)	0.7	0.9	2.2	-1.3	-0.6	-1.0	-1.4	-0.3	-0.5	-1.0	0.8	-1.5	0.5
High cholesterol (Self-reported)	0.5	0.8	2.2	-0.6	-1.1	-0.1	-0.5	-1.5	-0.8	0.0	-0.2	-1.1	1.4
Medication: Bendroflumethiazide	0.5	0.8	3.0	-1.7	-0.7	-1.1	-0.8	-0.8	0.6	-0.8	0.9	-0.5	0.5
Medication: Paracetamol	0.5	0.8	2.9	1.7	0.3	1.4	0.8	0.1	1.3	0.6	-0.6	0.6	0.3
Medication: Lisinopril	0.2	0.3	1.9	-0.2	0.3	1.4	0.7	-0.0	0.2	0.1	0.2	0.2	0.1
Medication: Atorvastatin	1.2	1.5	3.0	0.7	-1.1	-1.3	-1.3	-1.6	1.0	1.7	-1.3	-0.9	1.1
Illnesses of father: High blood pressure	0.4	0.5	2.1	0.7	-0.2	1.4	1.2	-0.2	0.1	0.8	-0.3	0.3	0.7
Alcohol drinker status: Never	0.7	0.9	3.4	-1.9	-0.2	-0.6	0.0	1.0	-1.3	-1.1	0.7	-0.1	-0.8
Ever smoked	0.5	0.9	3.4	-0.3	-1.1	0.4	0.6	0.5	-0.3	-1.9	1.7	-0.7	-0.4
Basal metabolic rate	1.6	8.8	14.8	-3.9	-3.1	-3.5	-2.4	-0.9	-3.2	-3.7	3.5	-2.7	0.5
Leg fat percentage (left)	1.6	5.9	10.2	-2.5	-2.9	-2.5	-2.1	-1.1	-2.2	-3.1	3.2	-2.7	0.7
Arm fat-free mass (left)	1.6	7.9	12.5	-3.5	-3.3	-3.4	-2.4	-0.8	-3.0	-3.3	3.2	-2.7	0.4
Number of operations (self-reported)	2.6	3.9	15.2	2.5	-0.4	-0.4	-0.9	-0.5	2.0	3.9	-3.5	-0.3	-0.2
Average weekly beer plus cider intake	1.7	2.4	6.8	-1.4	1.4	0.8	1.2	0.8	-1.8	-2.6	2.3	1.2	-0.8
Irritability	0.8	1.3	4.2	2.0	1.0	1.5	1.1	0.9	-0.7	0.6	-0.7	1.5	-0.5
Risk taking	1.5	2.2	7.5	0.3	2.7	0.6	1.7	1.3	-0.3	-1.2	0.8	2.3	-1.4
Ever had prostate specific antigen (PSA) test	0.2	0.3	1.0	0.1	0.0	-0.4	-0.3	0.7	-1.0	0.1	0.5	0.1	-0.8
Fractured/broken bones in last 5 years	0.3	0.4	1.5	0.6	-0.7	0.9	1.2	-0.0	0.1	-0.2	0.0	-0.8	-0.1
Age started oral contraceptive pill	0.7	0.8	2.6	-0.9	-1.6	-0.3	-0.7	-0.8	0.7	-1.1	0.5	-1.2	0.6
Diastolic blood pressure, automated reading	3.1	9.7	19.9	-4.5	-3.7	-3.7	-2.7	-0.8	-1.9	-3.6	4.0	-2.9	0.3
Ever depressed for a whole week	0.5	0.7	3.0	0.3	-0.5	-1.7	-0.4	0.8	-0.4	-0.2	0.3	0.3	-1.5
Unable to work because of sickness or disability	0.2	0.2	0.8	0.4	0.4	0.4	0.3	-0.8	0.2	0.5	-0.9	0.2	0.4
Commuting to job workplace: Cycle	2.3	2.7	8.6	-2.9	0.3	-1.8	-0.0	1.4	-0.6	-2.1	2.3	-0.7	-1.6
Myopia	1.2	1.7	4.5	-0.2	1.2	0.0	0.7	1.4	-2.1	-1.5	1.7	1.2	-1.3
Vascular/heart problems diagnosed by doctor	0.5	1.3	3.8	0.9	1.9	1.5	1.4	0.9	0.7	1.1	-0.6	1.1	-0.8
Cholesterol lowering medication	0.3	0.5	1.6	-0.2	0.4	1.0	0.5	-1.2	-0.1	0.5	-0.3	0.5	1.1
Medication: Omeprazole (e.g. Zanprol)	1.6	1.9	4.2	2.1	1.7	1.2	0.9	0.2	0.9	2.0	-1.5	1.5	-0.5
Pain experienced in last month	0.5	0.8	2.9	-1.3	-0.4	-1.1	-1.7	-0.9	-0.3	-0.5	0.1	-0.5	1.0
Supplements: Calcium	0.4	0.4	1.1	1.1	0.2	0.6	0.6	0.8	0.9	0.2	-0.4	0.1	-0.9
Basal cell carcinoma (self-reported)	1.5	1.8	5.4	2.2	1.3	2.3	1.0	-0.3	0.2	1.4	-0.6	1.6	0.5
Heart attack/myocardial infarction (self-reported)	0.9	1.1	3.6	-0.3	-0.7	-1.0	-1.6	-1.9	-0.1	0.0	-0.2	-1.1	1.5
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	0.9	1.0	0.2	0.2	0.2	-0.5	-0.7	-0.1	-0.3	-0.6	0.5
Heart disease (siblings)	0.7	0.8	2.8	-1.2	-1.7	-0.8	-0.2	-0.6	-0.2	-1.0	0.7	-1.0	0.5
Alcohol drinker status: Previous	0.6	0.6	2.6	-0.2	0.6	1.6	0.7	-0.7	0.4	0.3	-0.6	0.5	1.2
Pack years of smoking	1.6	2.3	4.9	0.2	2.0	1.6	1.9	1.7	-1.3	-0.9	1.1	2.2	-1.3
Impedance of whole body	1.3	6.4	11.5	3.4	2.6	1.9	2.1	1.8	1.4	3.4	-3.2	2.9	-1.5
Leg fat mass (left)	2.4	9.5	15.7	-3.4	-3.5	-3.5	-2.7	-1.4	-3.0	-4.0	3.8	-3.1	0.9
Arm predicted mass (left)	1.5	7.7	12.2	-3.5	-3.4	-3.4	-2.6	-1.1	-2.6	-3.0	3.0	-2.9	0.7