Best TWAS P=4.43e-10 · Best GWAS P=1.37e-09 conditioned to 0.000375
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | RP11-848P1.7 | 0.54 | 0.00 | lasso | 10 | 0.02 | 0.0073 | 5.0 | 6.2 | 4.4e-10 | 0.47 | 0.02 | 0.11 | TRUE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | GOSR1 | 0.02 | 0.01 | enet | 4 | 0.01 | 0.0167 | 5.1 | -5.3 | 1.5e-07 | -0.27 | 0.01 | 0.75 | FALSE |