[Hub]/) : Traits : Crohns Disease (2017) : ← →

chr3:52,242,902-53,860,103

Best TWAS P=4.55e-09 · Best GWAS P=7.93e-09 conditioned to 0.303

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
14	GTEx	Muscle Skeletal	RFT1	0.17	0.16	enet	17	0.15	3.0e-14	5.2	5.9	4.6e-09	0.91	0.03	0.97	TRUE
8	GTEx	Breast Mammary Tissue	RFT1	0.24	0.14	lasso	8	0.15	3.1e-08	5.8	5.8	7.3e-09	0.99	0.00	1.00	FALSE
21	GTEx	Thyroid	RFT1	0.36	0.33	enet	17	0.35	2.4e-27	5.2	5.6	2.4e-08	0.93	0.02	0.98	FALSE
9	GTEx	Breast Mammary Tissue (Male)	RFT1	0.23	0.12	enet	8	0.13	5.5e-04	5.2	5.5	3.7e-08	0.94	0.01	0.87	FALSE
12	GTEx	Esophagus Gastroesophageal Junction	RFT1	0.43	0.37	enet	18	0.34	7.0e-13	5.2	5.5	4.4e-08	0.92	0.02	0.98	FALSE
20	GTEx	Testis	RFT1	0.20	0.12	enet	8	0.10	2.9e-05	5.2	5.5	4.5e-08	0.95	0.01	0.98	FALSE
10	GTEx	Cells Transformed fibroblasts	RFT1	0.22	0.21	enet	16	0.22	2.8e-16	5.2	5.4	5.9e-08	0.94	0.01	0.99	FALSE
3	GTEx	Adipose Visceral Omentum	RFT1	0.16	0.15	enet	12	0.10	1.0e-05	5.2	5.4	7.6e-08	0.84	0.04	0.96	FALSE
4	GTEx	Adrenal Gland	RFT1	0.15	0.02	enet	11	0.03	4.0e-02	5.2	5.3	9.0e-08	0.93	0.01	0.95	FALSE
11	GTEx	Colon Sigmoid	RFT1	0.55	0.45	enet	15	0.43	1.0e-16	5.2	5.3	1.1e-07	0.91	0.03	0.97	FALSE
13	GTEx	Lung	RFT1	0.24	0.23	enet	12	0.23	2.7e-17	5.2	5.3	1.1e-07	0.91	0.03	0.97	FALSE
23	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	RFT1	0.15	0.21	lasso	8	0.22	1.4e-24	5.2	5.3	1.2e-07	0.91	0.05	0.95	FALSE
6	GTEx	Brain Frontal Cortex BA9	RFT1	0.23	0.10	enet	17	0.10	1.4e-03	5.2	5.3	1.5e-07	0.85	0.02	0.93	FALSE
2	GTEx	Adipose Subcutaneous	RFT1	0.21	0.19	enet	24	0.17	3.7e-14	5.2	5.2	1.6e-07	0.86	0.04	0.96	FALSE
15	GTEx	Nerve Tibial	RFT1	0.35	0.31	enet	17	0.27	1.9e-19	5.2	5.2	1.8e-07	0.89	0.04	0.96	FALSE
17	GTEx	Skin Sun Exposed Lower leg	RFT1	0.18	0.16	enet	7	0.13	1.1e-10	5.2	5.2	2.2e-07	0.88	0.03	0.96	FALSE
19	GTEx	Spleen	RFT1	0.23	0.22	enet	7	0.13	3.6e-04	5.2	5.2	2.2e-07	0.88	0.03	0.89	FALSE
1	CommonMind	Brain Pre-frontal Cortex	RFT1	0.21	0.22	lasso	3	0.22	5.7e-26	5.2	5.2	2.5e-07	0.87	0.06	0.94	FALSE
18	GTEx	Small Intestine Terminal Ileum	RFT1	0.20	0.20	enet	19	0.11	2.2e-03	5.2	5.2	2.5e-07	0.86	0.03	0.90	FALSE
22	METSIM	Adipose	RFT1	0.13	0.19	lasso	7	0.18	7.8e-27	5.2	5.2	2.6e-07	0.88	0.06	0.94	FALSE
16	GTEx	Nerve Tibial	SFMBT1	0.21	0.10	enet	11	0.07	1.4e-05	5.2	-5.2	2.7e-07	-0.88	0.03	0.97	FALSE
5	GTEx	Artery Coronary	RFT1	0.38	0.33	lasso	5	0.34	2.6e-12	5.2	5.1	2.8e-07	0.88	0.04	0.96	FALSE
24	The Cancer Genome Atlas	Thyroid Carcinoma	RFT1	0.25	0.30	lasso	4	0.29	3.8e-28	5.2	5.1	2.9e-07	0.87	0.06	0.93	FALSE
7	GTEx	Brain Nucleus accumbens basal ganglia	RFT1	0.26	0.16	lasso	4	0.10	1.1e-03	5.2	5.1	3.1e-07	0.87	0.02	0.92	FALSE