TWAS
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Usage
Models
Genes
Traits
[Hub]/) :
Traits
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Crohns Disease (2017)
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chr4:122,377,715-123,976,639
Best TWAS P=3.61e-08 · Best GWAS P=2.38e-08 conditioned to 0.173
122.4M
122.6M
122.8M
123M
123.2M
123.4M
123.6M
123.8M
124M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Colon Transverse
KIAA1109
0.25
-0.01
enet
16
0.00
4.1e-01
5.6
-5.5
3.6e-08
-0.91
0.03
0.70
TRUE
2
The Cancer Genome Atlas
Thyroid Carcinoma
KIAA1109
0.05
0.04
enet
3
0.05
5.4e-06
5.6
-5.5
4.8e-08
-0.97
0.01
0.99
FALSE