Best TWAS P=1.17e-18 · Best GWAS P=7.54e-22 conditioned to 0.00012
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Lung Adenocarcinoma | IL12B | 0.07 | 0.00 | blup | 48 | 0.04 | 8.0e-06 | -5.3 | 8.8 | 1.2e-18 | -0.89 | 0.02 | 0.64 | TRUE |
2 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | IL12B | 0.15 | 0.04 | blup | 48 | 0.08 | 8.9e-10 | -5.3 | 7.1 | 1.7e-12 | -0.51 | 0.03 | 0.97 | FALSE |