TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Crohns Disease (2017)
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chr5:158,501,850-159,005,439
Best TWAS P=1.17e-18 · Best GWAS P=7.54e-22 conditioned to 0.00012
158.5M
158.6M
158.7M
158.8M
158.9M
159M
0
5
10
15
20
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
The Cancer Genome Atlas
Lung Adenocarcinoma
IL12B
0.07
0.00
blup
48
0.04
8.0e-06
-5.3
8.8
1.2e-18
-0.89
0.02
0.64
TRUE
2
The Cancer Genome Atlas
Lung Squamous Cell Carcinoma
IL12B
0.15
0.04
blup
48
0.08
8.9e-10
-5.3
7.1
1.7e-12
-0.51
0.03
0.97
FALSE