Best TWAS P=3.68e-14 · Best GWAS P=1.58e-16 conditioned to 0.00102
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | IGHEP2 | 0.08 | 0.07 | enet | 12 | 0.08 | 3.7e-10 | 7.4 | -7.6 | 3.7e-14 | -0.91 | 1.00 | 0.00 | TRUE |
| 2 | YFS | Blood | JAK2 | 0.03 | 0.03 | lasso | 4 | 0.03 | 1.4e-10 | -4.1 | 5.7 | 1.0e-08 | 0.71 | 0.99 | 0.01 | FALSE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | JAK2 | 0.07 | 0.00 | blup | 83 | 0.02 | 2.2e-03 | 7.4 | 5.5 | 3.8e-08 | 0.70 | 0.03 | 0.08 | FALSE |