Best TWAS P=4.26e-21 · Best GWAS P=1.75e-21 conditioned to 0.0461
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | TNFSF15 | 0.05 | 0.06 | lasso | 3 | 0.06 | 5.4e-09 | -9.2 | -9.4 | 4.3e-21 | 0.82 | 0.03 | 0.97 | TRUE |
| 2 | NTR | Blood | TNFSF8 | 0.05 | 0.04 | enet | 4 | 0.04 | 2.3e-13 | 6.7 | -5.7 | 1.3e-08 | 0.11 | 1.00 | 0.00 | TRUE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | TNFSF15 | 0.02 | 0.01 | blup | 54 | 0.01 | 7.6e-03 | -9.2 | -9.2 | 3.6e-20 | 0.73 | 0.01 | 0.62 | FALSE |