Best TWAS P=1.11e-13 · Best GWAS P=4.69e-24 conditioned to 1.91e-10
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | C11orf30 | 0.07 | 0.06 | lasso | 6 | 0.06 | 2.1e-07 | 6.4 | -5.9 | 3.3e-09 | -0.68 | 0.72 | 0.28 | TRUE |
2 | GTEx | Adipose Visceral Omentum | LRRC32 | 0.21 | 0.00 | enet | 15 | 0.01 | 1.5e-01 | 9.9 | 7.4 | 1.1e-13 | 0.62 | 0.01 | 0.84 | TRUE |
3 | YFS | Blood | LRRC32 | 0.02 | 0.00 | bslmm | 481 | 0.00 | 9.1e-02 | 6.5 | -6.5 | 1.0e-10 | -0.62 | 0.07 | 0.75 | FALSE |