TWAS hub - LRRC32

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Visceral Omentum	0.2130	0.0750	0.0089	-0.002	NA	0.006	NA	0.001	0.46	NA	0.15	NA	0.28
2	YFS	Blood	0.0164	0.0069	0.0044	-0.001	0.001	0.000	0.001	-0.001	0.66	0.092	0.52	0.091	0.77

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Allergy	53.8	123.7	185.0	-13.6	7.9
Allergy or Eczema	51.6	135.9	194.2	13.9	-8.8
Hayfever, allergic rhinitis or eczema	50.1	108.6	156.6	12.5	-7.8
Asthma	35.8	70.7	114.5	10.7	-5.2
Asthma (self-reported)	33.9	67.4	108.2	10.4	-5.2
Respiratory disease	33.3	74.1	117.8	10.9	-5.5
Hayfever/allergic rhinitis (self-reported)	28.4	37.5	53.8	7.3	-4.6
Irritable Bowel Disease (IBD)	23.8	56.7	57.7	7.5	-7.6
Blood Eosinophil Count	22.3	172.0	272.2	16.5	-8.5
Crohns Disease (2017)	22.1	48.5	55.2	7.4	-6.5
Medication: Ventolin 100micrograms inhaler	13.3	17.1	22.1	4.7	-3.5
Ulcerative Colitis (UC)	12.7	23.8	28.4	4.4	-5.3
Crohns Disease (2012)	11.8	18.9	25.0	5.0	-3.6
Rheumatoid Arthritis	10.5	14.4	20.5	-2.9	4.5
Ulcerative Colitis	10.2	14.8	19.3	3.2	-4.4
Chronic bronchitis/emphysema (mother)	10.2	11.9	13.0	3.3	-3.6
Shortness of breath walking on level ground	9.4	11.2	20.0	4.5	-1.5
Wheeze or whistling in the chest in last year	8.4	14.9	28.5	5.3	-1.2
Number of self-reported non-cancer illnesses	8.3	14.4	23.0	4.8	-2.4
Prostate Cancer	6.3	8.8	9.4	-2.9	3.1
Illnesses of mother	5.7	7.0	8.6	-2.3	2.9
Eye problems/disorders: None of the above	5.0	5.7	8.9	1.6	-3.0
Relative age of first facial hair	4.7	9.7	16.1	1.8	-4.0
Impedance of arm (right)	4.7	22.1	28.4	5.3	-4.0
Severe depression (siblings)	4.5	5.1	9.4	3.1	-0.8
Age when periods started (menarche)	4.5	10.8	11.5	3.2	-3.4
Impedance of arm (left)	4.3	20.1	24.0	4.9	-4.0
Long-standing illness, disability or infirmity	4.2	6.4	10.7	3.3	-1.4
Mother’s age at death	4.2	5.2	8.7	1.3	-3.0
Medication: Seretide 50 evohaler	4.0	4.6	5.2	2.3	-2.0
Eye problems/disorders: Diabetes related eye disease	3.9	4.3	7.3	-1.1	2.7
Type 2 Diabetes (T2D) (2012)	3.8	4.4	6.1	-2.5	1.6
Serious illness, injury or assault to yourself	3.3	4.0	5.1	2.3	-1.7
Relative age voice broke	3.2	4.9	6.3	1.9	-2.5
Multivitamins +/- minerals	3.2	4.0	4.6	2.1	-1.9
Taking other prescription medications	3.1	4.9	9.0	3.0	-0.8
Diabetes (mother)	2.9	3.7	6.9	-0.8	2.6
Medication: Simvastatin	2.9	4.3	5.9	-2.4	1.6
Supplements: Zinc	2.8	3.1	5.7	2.4	-0.7
Heart disease (siblings)	2.8	3.5	4.5	2.1	-1.6
Alzheimer’s Disease (in father)	2.7	2.9	3.6	1.5	-1.9
Number of treatments/medications taken	2.7	4.8	7.9	2.8	-1.3
Commuting to job workplace: Cycle	2.6	3.2	5.9	-2.4	0.7
Type 2 Diabetes (T2D) (2018)	2.5	4.7	5.3	-2.0	2.3
Illnesses of siblings	2.5	3.6	5.8	-2.4	1.2
Ever smoked	2.5	4.4	7.6	2.8	-1.1
Unable to work because of sickness or disability	2.5	3.3	6.4	2.5	-0.5
Cholesterol lowering medication	2.5	3.7	4.5	-2.1	1.7
Impedance of whole body	2.5	12.6	16.9	4.1	-2.9
Medication: Amlodipine	2.4	3.3	3.6	1.9	-1.7
Irritability	2.4	4.1	4.7	1.9	-2.2
Medication: Co-codamol	2.3	2.7	4.9	2.2	-0.6
Mood swings	2.3	4.2	7.8	2.8	-0.7
Hypothyroidism (self reported)	2.2	5.0	5.7	2.1	2.4
Mouth/teeth dental problems	2.2	3.3	4.8	-2.2	1.4
Medication: Ibuprofen (e.g. Nurofen)	2.2	2.8	3.0	-1.6	1.7
Mouth/teeth dental problems: Bleeding gums	2.1	2.8	4.6	2.1	-1.0
Guilty feelings	2.1	3.2	4.2	2.0	-1.5
Neuroticism (Nagel 2018)	2.0	4.7	8.0	2.8	-1.2
Chronic bronchitis/emphysema (father)	2.0	2.4	4.6	2.1	-0.4
Frequency of tenseness / restlessness in last 2 weeks	2.0	3.1	4.6	2.1	-1.3
Mean time to correctly identify matches	2.0	3.8	6.3	2.5	-1.2
Loneliness, isolation	2.0	2.8	3.2	1.8	-1.6
Age started oral contraceptive pill	2.0	2.5	4.0	-2.0	1.0
Reaction Time	1.9	3.7	6.9	2.6	-0.6
Hearing difficulty/problems: Yes	1.9	2.8	3.8	1.3	-2.0
Handedness (chirality/laterality): Left-handed	1.9	2.2	4.4	-0.1	2.1
Schizophrenia (2018)	1.8	3.7	6.7	2.6	-0.9
Breast Cancer	1.8	4.3	5.2	-1.8	2.3
Ever had hysterectomy (womb removed)	1.8	2.1	3.9	-0.5	2.0
Medication: Lansoprazole	1.8	2.0	2.2	1.3	-1.5
Tense / ‘highly strung’	1.8	2.9	5.5	2.4	-0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	1.8	2.7	5.1	-0.7	2.2
Pulse rate, automated reading	1.8	5.9	11.6	-0.4	3.4
Diabetes diagnosed by doctor	1.8	2.9	3.6	-1.5	1.9
Neuroticism score	1.7	3.6	5.7	2.4	-1.2
Exposure to tobacco smoke outside home	1.7	2.3	2.9	1.7	1.3
Medication: Ibuprofen	1.7	2.1	2.1	-1.4	1.4
Suffer from ‘nerves’	1.7	2.7	4.9	2.2	-0.7
Supplements: Fish oil (including cod liver oil)	1.7	2.3	2.6	1.6	-1.4
Depressed Affect (Nagel 2018)	1.6	3.3	5.2	2.3	-1.2
High blood pressure (mother)	1.6	2.3	2.5	1.4	-1.6
Fluid intelligence score	1.6	3.3	5.4	-2.3	1.1
Comparative body size at age 10	1.6	4.5	6.0	-2.4	1.8
Osteoarthritis (self-reported)	1.6	2.0	2.2	-1.5	1.4
Neuroticism	1.5	3.6	4.1	2.0	-1.8
Past tobacco smoking	1.5	2.8	5.6	-2.4	0.4
Health satisfaction	1.5	2.0	4.0	2.0	0.1
Illnesses of siblings: Diabetes	1.5	1.9	3.7	1.9	-0.1
High cholesterol (Self-reported)	1.5	2.7	4.5	-2.1	0.9
Alcohol drinker status: Previous	1.5	1.7	3.0	1.7	-0.6
Mean Putamen Volume	1.4	1.6	2.2	1.5	-1.0
Systolic Blood Pressure	1.4	7.0	8.1	2.8	-2.5
Vitamin and mineral supplements	1.4	1.9	2.6	-1.6	1.1
Medication: Atenolol	1.4	1.7	2.8	-0.8	1.7
Diabetes (self-reported)	1.4	2.2	3.6	-0.9	1.9
Qualifications: A levels/AS levels or equivalent	1.4	3.1	3.3	-1.8	1.7
Breastfed as a baby	1.4	1.7	3.3	-1.8	-0.4
Glaucoma (self-reported)	1.4	1.6	3.2	-1.8	0.2
Hypothyroidism/myxoedema (self-reported)	1.4	2.7	3.4	1.4	1.8
High blood pressure (siblings)	1.4	2.0	2.2	1.4	-1.5
Worry too long after embarrassment	1.4	2.4	2.7	1.4	-1.7
Chest pain or discomfort	1.4	2.1	2.9	1.7	-1.1
Alcohol drinker status: Never	1.4	1.7	1.8	-1.3	1.4
Schizophrenia (2014)	1.3	2.9	4.7	2.2	-1.1
Tinnitus: Yes, but not now, but have in the past	1.3	1.4	2.0	-0.9	1.4
Heart attack	1.3	1.7	3.2	1.8	-0.5
Supplements: Vitamin C	1.3	1.5	1.9	-1.4	1.1
Miserableness	1.3	2.2	4.2	2.0	-0.5
Coronary Artery Disease (CAD)	1.2	1.4	2.3	1.5	-0.8
Fasting Glucose	1.2	1.4	2.4	1.6	-0.7
Lung FEV1/FVC ratio	1.2	5.9	10.9	-3.3	1.0
Pack years adult smoking proportion	1.2	1.8	2.7	1.0	1.6
Medication: Levothyroxine sodium	1.2	2.1	3.2	1.8	1.0
Exposure to tobacco smoke at home	1.2	1.3	2.5	1.6	-0.3
Had major operations	1.2	1.4	1.7	1.0	-1.3
Age at last live birth	1.2	1.7	2.8	0.8	-1.7
BMI	1.1	6.3	9.3	-1.8	3.0
Medication: Metformin	1.1	1.5	2.5	-0.7	1.6
Current tobacco smoking	1.1	1.7	2.9	1.7	-0.8
Nervous feelings	1.1	2.0	3.8	1.9	-0.5
Forced expiratory volume in 1-second (FEV1)	1.1	3.7	7.0	-2.6	-0.7
Birth weight of first child	1.1	1.9	3.9	-2.0	-0.1
Peak expiratory flow (PEF)	1.1	2.7	4.4	-2.1	1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.1	1.3	1.5	1.2	1.0
Leg pain on walking	1.1	1.4	2.3	1.5	0.7
Heart attack/myocardial infarction (self-reported)	1.1	1.4	2.6	1.6	-0.5
Pack years of smoking	1.1	1.7	2.0	1.1	1.4
Depression (Nagel 2018)	1.0	1.6	2.0	1.4	-1.1
Ovarian Cancer	1.0	1.3	2.5	-0.4	1.6
Height	1.0	19.4	29.6	3.0	-5.4
Hand grip strength (right)	1.0	2.6	3.5	-1.9	1.3
Had other major operations	1.0	1.2	2.3	-1.5	-0.1
Friendships satisfaction	1.0	1.2	1.9	-1.4	0.7
Bipolar Disorder or Schizophrenia	0.9	2.1	3.9	2.0	-0.6
HDL Cholesterol	0.9	1.5	2.9	-1.7	-0.1
Blood Platelet Count	0.9	10.3	11.3	3.4	3.1
Hand grip strength (left)	0.9	2.3	2.4	-1.5	1.5
Other serious medical condition/disability diagnosed by doctor	0.9	1.2	2.2	0.4	-1.5
Hair/balding pattern: Pattern 2	0.9	1.2	1.8	-0.8	1.3
Father’s age at death	0.9	1.1	1.2	-1.0	1.1
Gout (self-reported)	0.9	1.2	2.2	1.5	-0.6
Birth weight	0.9	1.9	3.2	-1.8	0.7
Arm fat-free mass (right)	0.9	4.7	6.5	-2.5	1.7
Overall health rating	0.9	1.9	3.7	1.9	-0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.9	0.9	1.1	1.1	-0.9
Medication: Aspirin	0.9	1.1	1.3	1.0	-1.1
Tinnitus: Yes, now most or all of the time	0.9	1.0	1.2	0.9	-1.1
Fractured/broken bones in last 5 years	0.9	1.2	2.0	-1.4	0.6
Primary Biliary Cirrhosis	0.8	1.2	1.9	0.7	-1.4
Triglycerides	0.8	1.2	2.2	-0.5	1.5
Smoking Status	0.8	2.0	3.8	1.9	-0.4
Chronotype (morning person)	0.8	1.8	2.9	-1.7	0.9
Trunk fat percentage	0.8	3.3	6.7	2.6	0.1
Average weekly fortified wine intake	0.8	1.0	1.9	0.2	1.4
Supplements: Glucosamine	0.8	1.0	1.6	1.3	-0.6
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.4	2.5	1.6	-0.5
Pulse wave Arterial Stiffness index	0.8	1.0	1.3	-1.2	0.8
Blood clot in the leg (DVT)	0.8	1.0	1.8	1.4	-0.4
Emphysema/chronic bronchitis	0.8	0.9	1.8	1.3	-0.3
Smoking status: Previous	0.8	1.1	2.2	1.5	-0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.7	3.2	0.4	-1.8
Wears glasses or contact lenses	0.8	0.9	1.6	-1.2	0.6
Eye problems/disorders: Glaucoma	0.8	0.9	1.8	-1.3	-0.3
LDL Cholesterol	0.7	1.1	1.2	1.1	1.0
Lupus	0.7	1.0	1.6	-0.7	1.3
Frequency of depressed mood in last 2 weeks	0.7	1.0	1.5	1.2	-0.8
Impedance of leg (right)	0.7	3.3	5.9	2.4	-0.9
Townsend deprivation index at recruitment	0.7	1.0	1.8	1.4	-0.4
Fed-up feelings	0.7	1.3	1.8	1.4	-0.9
Stomach or abdominal pain in last month	0.7	0.8	1.3	-1.1	0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.6	2.1	1.5	-1.0
Ever unenthusiastic/disinterested for a whole week	0.7	0.8	1.1	-0.7	1.0
Pulse rate	0.7	1.2	2.1	0.5	1.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.3	2.9	-1.7	-1.4
Qualifications: O levels/GCSEs or equivalent	0.7	1.1	1.3	-1.0	1.1
Pulse wave peak to peak time	0.7	0.8	0.8	0.9	-0.9
Angina (self-reported)	0.7	0.9	1.2	-0.8	1.1
Arm predicted mass (right)	0.7	3.8	5.2	-2.3	1.5
Illness, injury, bereavement, stress in last 2 years	0.7	0.9	1.2	-0.7	1.1
Medication: Aspirin	0.7	0.9	1.3	0.7	-1.1
Ever had bowel cancer screening	0.7	0.8	1.6	0.2	-1.3
Qualifications: nursing, teaching	0.7	1.1	1.9	-1.4	0.6
Mineral and other dietary supplements	0.7	0.9	1.7	-1.3	0.3
Smoking status: Current	0.7	1.1	2.1	1.5	-0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.6	3.0	-1.7	0.3
Ever taken oral contraceptive pill	0.7	0.8	1.3	1.1	-0.6
Average weekly beer plus cider intake	0.7	1.0	2.1	0.0	1.4
Risk taking	0.7	1.0	2.0	-0.1	-1.4
Diastolic blood pressure, automated reading	0.7	2.3	4.2	0.6	-2.0
Ever depressed for a whole week	0.7	0.9	1.0	-1.0	0.9
Age at First Birth	0.6	0.8	1.7	-1.3	0.1
Blood White Count	0.6	4.7	4.8	2.1	2.2
Systolic blood pressure, automated reading	0.6	1.9	2.1	1.3	-1.5
Angina	0.6	0.8	0.9	-0.9	0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	1.6	1.3	-0.2
Qualifications: CSEs or equivalent	0.6	0.8	0.9	-0.9	0.9
Impedance of leg (left)	0.6	3.1	5.3	2.3	-0.9
Hearing difficulty/problems with background noise	0.6	1.0	1.5	0.7	-1.2
Arm fat percentage (right)	0.6	2.3	4.5	2.1	0.2
Depression (self-reported)	0.6	0.7	1.1	0.5	1.0
Lung cancer (father)	0.6	0.7	1.4	0.3	-1.2
Hair/balding pattern: Pattern 4	0.6	1.4	2.0	-1.4	0.9
Ever highly irritable/argumentative for 2 days	0.6	0.7	0.9	-0.6	1.0
Leg fat percentage (right)	0.6	2.1	3.8	0.7	1.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.6	0.9	0.9	0.7
Commuting to job workplace: Walk	0.6	0.7	1.2	-1.1	0.4
Illnesses of father: None of the above (group 1)	0.6	0.8	1.4	0.4	1.2
Deep venous thrombosis (DVT) (self-reported)	0.6	0.8	1.5	1.2	-0.2
Schizophrenia vs Biploar Disorder	0.5	0.7	1.4	0.1	-1.2
Worry (Nagel 2018)	0.5	1.1	2.1	1.5	-0.4
Body Mass Index (BMI) (2010)	0.5	0.7	1.4	1.2	-0.1
High blood pressure	0.5	1.4	1.7	1.3	-1.1
Forced vital capacity (FVC)	0.5	1.9	2.1	-1.5	-1.3
Hair/balding pattern: Pattern 3	0.5	0.8	1.4	-1.2	0.3
Prospective memory result	0.5	0.7	1.0	-0.5	1.0
Forced vital capacity (FVC), Best measure	0.5	1.9	3.5	-0.5	-1.9
Body fat percentage	0.5	2.0	3.5	1.9	0.7
Age at first live birth	0.5	0.9	1.6	0.3	-1.3
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	1.4	1.2	0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	1.2	-0.2	1.1
Medication: Blood pressure	0.5	1.0	2.0	1.4	0.3
Medication: Atorvastatin	0.5	0.6	1.0	0.4	-1.0
Leg fat percentage (left)	0.5	1.8	3.3	0.6	1.8
Number of operations (self-reported)	0.5	0.8	1.5	-0.4	-1.2
Major Depression (MDD)	0.4	0.5	0.9	1.0	0.1
Waist Hip Ratio (WHR)	0.4	1.8	2.1	1.4	1.2
Average weekly spirits intake	0.4	0.4	0.5	-0.6	0.7
Ever used hormone-replacement therapy (HRT)	0.4	0.5	0.5	0.7	0.7
Medication for hormone replacement therapy	0.4	0.5	1.0	1.0	-0.1
Body mass index (BMI)	0.4	1.9	3.7	-0.1	1.9
Trunk fat mass	0.4	1.5	2.9	1.7	0.4
Medication: Ramipril	0.4	0.5	1.1	0.0	-1.0
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.5	0.9	0.9	0.1
Standing height	0.4	3.6	6.0	1.1	-2.5
Medication: Paracetamol	0.4	0.7	1.2	1.1	-0.5
Number of full brothers	0.4	0.5	0.6	0.8	-0.7
Qualifications: College or University degree	0.4	1.4	2.5	-1.6	0.6
Medication: Blood pressure	0.4	0.8	1.2	0.6	-1.1
Family relationship satisfaction	0.4	0.5	0.6	-0.8	0.6
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	0.7	-0.4	0.9
Hypertension (Self-reported)	0.4	1.1	1.1	1.1	-1.0
Arm fat percentage (left)	0.4	1.7	3.1	1.8	0.6
Breast cancer (self-reported)	0.4	0.5	0.9	0.3	-0.9
Average weekly champagne plus white wine intake	0.4	0.6	0.9	-0.6	-1.0
Commuting to job workplace: Public transport	0.4	0.5	0.9	1.0	0.1
Medication: Paracetamol	0.4	0.6	1.1	1.0	-0.4
Illnesses of father: High blood pressure	0.4	0.5	0.8	-0.9	-0.4
Arm fat-free mass (left)	0.4	1.8	2.4	-1.5	1.1
Arm predicted mass (left)	0.4	1.9	2.3	-1.5	1.2
Heel T-Score	0.3	2.8	3.5	1.4	-1.9
Lung FVC	0.3	1.5	2.8	-1.7	-0.5
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	0.6	0.8	0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.6	0.8	0.9	-0.6
Waist circumference	0.3	1.0	1.6	1.3	0.7
Qualifications: None of the above	0.3	0.7	1.0	1.0	-0.5
Pain all over the body in last month	0.3	0.3	0.6	0.8	-0.3
Alcohol intake versus 10 years previously	0.3	0.5	0.9	1.0	0.1
Happiness	0.3	0.3	0.5	0.4	0.7
Pulse wave reflection index	0.3	0.4	0.7	-0.8	-0.3
Loud music exposure frequency	0.3	0.3	0.5	0.4	0.7
Headache pain in last month	0.3	0.6	0.7	0.7	-0.9
Mouth/teeth dental problems: Loose teeth	0.3	0.3	0.6	0.8	-0.2
Medication: Omeprazole	0.3	0.3	0.5	-0.4	0.7
Heart disease (mother)	0.3	0.3	0.6	0.8	-0.2
Leg fat mass (right)	0.3	1.3	2.6	0.3	1.6
Eye problems/disorders: Cataract	0.3	0.4	0.4	0.6	0.6
Pain type(s) experienced in last month: Hip pain	0.3	0.4	0.8	0.9	0.1
Basal cell carcinoma (self-reported)	0.3	0.3	0.5	0.3	-0.7
Leg fat mass (left)	0.3	1.2	2.3	0.3	1.5
Intelligence (Savage-Jansen 2018)	0.2	0.6	0.8	0.7	-0.9
Bipolar Disorder (2011)	0.2	0.2	0.4	0.0	0.6
Tanning	0.2	2.3	3.1	-1.8	1.2
Maternal smoking around birth	0.2	0.3	0.4	0.6	-0.4
Diverticular disease/diverticulitis (self-reported)	0.2	0.3	0.5	0.3	0.7
Number of incorrect matches in round	0.2	0.3	0.4	-0.6	0.4
Alcohol usually taken with meals	0.2	0.3	0.3	0.6	-0.5
Financial difficulties in last 2 years	0.2	0.3	0.6	-0.7	0.3
Trunk fat-free mass	0.2	1.1	2.0	-1.4	0.4
Noisy workplace	0.2	0.2	0.2	0.4	0.5
Mouth/teeth dental problems: Dentures	0.2	0.4	0.7	0.8	-0.1
Arm fat mass (right)	0.2	0.9	1.3	1.1	0.7
Trunk predicted mass	0.2	1.3	2.3	-1.5	0.4
Medication for pain relief, constipation, heartburn	0.2	0.3	0.5	0.7	-0.1
Neck or shoulder pain in last month	0.2	0.3	0.4	-0.4	0.7
Medication: Allopurinol	0.2	0.3	0.3	0.5	-0.5
Whole body fat mass	0.2	1.0	1.3	1.1	0.9
Comparative height size at age 10	0.2	1.1	1.5	0.8	-1.2
Whole body fat-free mass	0.2	0.9	1.6	-1.3	0.5
Back pain experienced in last month	0.2	0.3	0.5	0.7	-0.2
Whole body water mass	0.2	1.0	1.7	-1.3	0.6
Arm fat mass (left)	0.2	0.7	1.1	1.1	0.6
Ever had prostate specific antigen (PSA) test	0.2	0.2	0.3	0.6	-0.4
Myopia	0.2	0.3	0.5	-0.1	0.7
Vascular/heart problems diagnosed by doctor	0.2	0.5	0.8	-0.9	0.5
Pain experienced in last month	0.2	0.4	0.4	0.6	-0.6
Supplements: Calcium	0.2	0.2	0.3	0.6	0.3
Alzheimer’s Disease (in mother)	0.1	0.1	0.3	-0.5	-0.1
Verbal and Numeric Reasoning (VNR)	0.1	0.2	0.4	-0.6	0.1
HbA1C	0.1	0.1	0.2	-0.4	0.1
Neuroticism (2016)	0.1	0.2	0.3	0.5	0.3
Blood Red Count	0.1	0.8	1.6	-1.3	-0.0
Cardiovascular Disease	0.1	0.2	0.4	0.2	-0.7
Hair Pigment	0.1	3.4	6.4	0.7	-2.5
Sensitivity / hurt feelings	0.1	0.2	0.2	0.4	-0.5
Diabetes (father)	0.1	0.1	0.2	0.5	-0.1
Leg fat-free mass (left)	0.1	0.3	0.4	-0.6	0.4
Leg predicted mass (left)	0.1	0.3	0.5	-0.7	0.4
Had menopause	0.1	0.2	0.2	-0.3	0.5
Weight	0.1	0.4	0.8	0.2	0.9
Hip circumference	0.1	0.4	0.4	0.7	0.6
Worrier / anxious feelings	0.1	0.2	0.4	-0.1	0.6
Number of live births	0.1	0.1	0.2	0.4	-0.1
Medication: Cholesterol lowering	0.1	0.2	0.3	-0.6	0.0
Length of working week for main job	0.1	0.2	0.3	-0.1	0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.2	0.4	0.6	-0.0
Number of children fathered	0.1	0.1	0.3	-0.5	-0.0
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.1	0.3	-0.2
Migraine (self-reported)	0.1	0.2	0.3	-0.6	0.0
Alcohol intake frequency.	0.1	0.3	0.4	0.5	0.6
Number of full sisters	0.1	0.1	0.2	0.5	-0.2
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.2	0.3	-0.5
Knee pain experienced in last month	0.1	0.2	0.2	0.5	-0.3
Illnesses of father: Heart disease	0.1	0.1	0.2	-0.5	-0.2
Leg fat-free mass (right)	0.1	0.5	1.0	-1.0	0.3
Medication for cholesterol	0.1	0.2	0.3	-0.3	-0.6
Leg predicted mass (right)	0.1	0.5	0.9	-0.9	0.3
Financial situation satisfaction	0.1	0.1	0.2	0.0	0.4
Medication: Bendroflumethiazide	0.1	0.1	0.2	0.5	0.0
Basal metabolic rate	0.1	0.5	0.6	-0.8	0.6
Medication: Omeprazole (e.g. Zanprol)	0.1	0.1	0.2	0.2	0.4
Bipolar Disorder (2018)	0.0	0.1	0.1	-0.3	0.1
Alzheimer’s Disease (including proxy)	0.0	0.0	0.1	-0.2	-0.2
Sitting height	0.0	0.1	0.1	-0.1	-0.4
Time employed in main current job	0.0	0.0	0.1	-0.3	-0.1
Falls in the last year	0.0	0.0	0.0	-0.1	-0.1
Medication for cholesterol, blood pressure or diabetes	0.0	0.0	0.0	0.0	-0.2
Average weekly red wine intake	0.0	0.0	0.0	0.2	-0.1
Osteoporosis (self-reported)	0.0	0.0	0.0	-0.2	-0.2
Medication: Gliclazide	0.0	0.0	0.0	0.0	-0.2
Hearing aid user	0.0	0.0	0.0	0.2	-0.1
Medication: Lisinopril	0.0	0.0	0.1	-0.0	0.3

Hub : Genes

LRRC32

Models

Trait associations