TWAS
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About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Crohns Disease (2017)
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chr22:29,585,080-31,118,395
Best TWAS P=2.67e-08 · Best GWAS P=4.19e-07 conditioned to 0.187
29.6M
29.8M
30M
30.2M
30.4M
30.6M
30.8M
31M
31.2M
0
2
4
6
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Thyroid Carcinoma
MTMR3
0.21
0.08
blup
72
0.16
2.5e-15
5.1
-5.6
2.7e-08
-0.75
0.01
0.99
TRUE
1
GTEx
Esophagus Gastroesophageal Junction
MTMR3
0.19
0.06
lasso
4
0.04
1.8e-02
-4.0
-5.2
1.8e-07
-0.54
0.06
0.37
FALSE