Best TWAS P=2.67e-08 · Best GWAS P=4.19e-07 conditioned to 0.187
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Esophagus Gastroesophageal Junction | MTMR3 | 0.19 | 0.06 | lasso | 4 | 0.04 | 1.8e-02 | -4.0 | -5.2 | 1.8e-07 | -0.54 | 0.06 | 0.37 | FALSE |
2 | The Cancer Genome Atlas | Thyroid Carcinoma | MTMR3 | 0.21 | 0.08 | blup | 72 | 0.16 | 2.5e-15 | 5.1 | -5.6 | 2.7e-08 | -0.75 | 0.01 | 0.99 | TRUE |