TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Crohns Disease (2017)
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chr22:36,500,899-37,910,395
Best TWAS P=4.89e-10 · Best GWAS P=1.76e-08 conditioned to 0.491
36.6M
36.8M
37M
37.2M
37.4M
37.6M
37.8M
0
2
4
6
8
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Prostate Adenocarcinoma
NCF4
0.05
0.02
lasso
4
0.04
1.9e-05
5.6
-6.2
4.9e-10
-0.85
0
0.99
TRUE
1
NTR
Blood
PVALB
0.09
0.08
bslmm
674
0.07
6.8e-23
5.6
-5.8
5.0e-09
-0.99
0
1.00
FALSE
3
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
NCF4
0.08
0.06
enet
4
0.05
1.4e-06
5.4
-5.7
9.4e-09
-0.89
0
1.00
FALSE
2
The Cancer Genome Atlas
Breast Invasive Carcinoma
NCF4
0.06
0.05
lasso
3
0.04
1.7e-09
5.6
-5.7
1.2e-08
-0.99
0
1.00
FALSE