Best TWAS P=4.89e-10 · Best GWAS P=1.76e-08 conditioned to 0.491
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | NTR | Blood | PVALB | 0.09 | 0.08 | bslmm | 674 | 0.07 | 6.8e-23 | 5.6 | -5.8 | 5.0e-09 | -0.99 | 0 | 1.00 | FALSE |
2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | NCF4 | 0.06 | 0.05 | lasso | 3 | 0.04 | 1.7e-09 | 5.6 | -5.7 | 1.2e-08 | -0.99 | 0 | 1.00 | FALSE |
3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | NCF4 | 0.08 | 0.06 | enet | 4 | 0.05 | 1.4e-06 | 5.4 | -5.7 | 9.4e-09 | -0.89 | 0 | 1.00 | FALSE |
4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | NCF4 | 0.05 | 0.02 | lasso | 4 | 0.04 | 1.9e-05 | 5.6 | -6.2 | 4.9e-10 | -0.85 | 0 | 0.99 | TRUE |