TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Crohns Disease (2017)
:
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chr2:42,753,863-44,157,441
Best TWAS P=4.02e-09 · Best GWAS P=1.52e-11 conditioned to 9.25e-05
42.8M
43M
43.2M
43.4M
43.6M
43.8M
44M
44.2M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Thyroid
AC010883.5
0.11
0.09
lasso
2
0.08
1.5e-06
5.8
5.9
4.0e-09
0.63
0.61
0.38
TRUE
1
GTEx
Nerve Tibial
ZFP36L2
0.06
0.00
lasso
8
0.01
3.5e-02
5.3
-5.7
9.5e-09
-0.80
0.05
0.82
FALSE
3
The Cancer Genome Atlas
Lung Adenocarcinoma
ZFP36L2
0.03
0.01
blup
38
0.01
1.1e-02
4.7
-5.4
7.8e-08
-0.56
0.02
0.52
FALSE