Best TWAS P=4.02e-09 · Best GWAS P=1.52e-11 conditioned to 9.25e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Nerve Tibial | ZFP36L2 | 0.06 | 0.00 | lasso | 8 | 0.01 | 3.5e-02 | 5.3 | -5.7 | 9.5e-09 | -0.80 | 0.05 | 0.82 | FALSE |
| 2 | GTEx | Thyroid | AC010883.5 | 0.11 | 0.09 | lasso | 2 | 0.08 | 1.5e-06 | 5.8 | 5.9 | 4.0e-09 | 0.63 | 0.61 | 0.38 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | ZFP36L2 | 0.03 | 0.01 | blup | 38 | 0.01 | 1.1e-02 | 4.7 | -5.4 | 7.8e-08 | -0.56 | 0.02 | 0.52 | FALSE |