Best TWAS P=3.28e-08 · Best GWAS P=1.75e-08 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Esophagus Mucosa | RP5-1115A15.1 | 0.06 | 0.06 | lasso | 4 | 0.05 | 3.0e-04 | 4.9 | -5.2 | 2.1e-07 | -0.95 | 0.01 | 0.96 | FALSE |
2 | GTEx | Lung | RP5-1115A15.1 | 0.05 | 0.08 | lasso | 1 | 0.07 | 1.0e-05 | 5.5 | -5.5 | 4.2e-08 | -1.00 | 0.00 | 1.00 | FALSE |
3 | GTEx | Thyroid | RP5-1115A15.1 | 0.09 | 0.12 | lasso | 2 | 0.09 | 1.5e-07 | 5.5 | -5.5 | 3.3e-08 | -0.99 | 0.00 | 1.00 | TRUE |
4 | YFS | Blood | RERE | 0.09 | 0.15 | lasso | 4 | 0.16 | 5.7e-49 | 5.6 | -5.2 | 1.9e-07 | -0.98 | 0.00 | 1.00 | FALSE |