690 significantly associated models · 109 unique genes
.
# | chr | p0 | p1 | # assoc genes | # joint genes | best TWAS P | best SNP P | cond SNP P | % var exp | joint genes |
---|---|---|---|---|---|---|---|---|---|---|
1 | 1 | 7715776 | 9571422 | 2 | 1 | 3.3e-08 | 1.8e-08 | 1.0e+00 | 100 | RP5-1115A15.1 |
2 | 1 | 86635245 | 88508392 | 2 | 2 | 1.7e-07 | 3.1e-06 | 2.4e-02 | 77 | LMO4 SEP15 |
3 | 1 | 242590540 | 244112606 | 1 | 1 | 2.7e-07 | 1.6e-06 | 4.1e-01 | 97 | CEP170 |
4 | 2 | 23453834 | 25141538 | 4 | 1 | 1.3e-11 | 5.4e-11 | 9.0e-03 | 84 | UBXN2A |
5 | 2 | 147993969 | 149475737 | 2 | 1 | 7.1e-08 | 9.5e-10 | 2.4e-03 | 76 | ORC4L |
6 | 2 | 202952678 | 204421284 | 1 | 1 | 2.3e-07 | 2.2e-06 | 6.0e-01 | 99 | ICA1L |
7 | 2 | 219863589 | 220358586 | 2 | 1 | 4.9e-08 | 3.7e-07 | 7.4e-02 | 88 | GLB1L |
8 | 3 | 16154636 | 17814553 | 1 | 1 | 8.2e-08 | 3.3e-10 | 1.5e-04 | 64 | PLCL2 |
9 | 3 | 48335857 | 50800146 | 22 | 1 | 8.3e-15 | 4.2e-10 | 3.0e-01 | 97 | GPX1 |
10 | 3 | 135806811 | 136715468 | 1 | 1 | 1.1e-09 | 2.6e-09 | 1.0e+00 | 100 | STAG1 |
11 | 5 | 87104604 | 88677293 | 1 | 1 | 8.9e-08 | 1.9e-09 | 6.4e-03 | 79 | LINC00461 |
12 | 5 | 119109286 | 120721018 | 1 | 1 | 7.4e-09 | 1.7e-08 | 1.0e+00 | 100 | PRR16 |
13 | 7 | 1580921 | 2977732 | 1 | 1 | 6.9e-08 | 6.3e-08 | 3.5e-03 | 71 | FTSJ2 |
14 | 7 | 11553163 | 12967449 | 1 | 1 | 1.2e-10 | 5.1e-11 | 1.0e+00 | 100 | TMEM106B |
15 | 8 | 21720054 | 22214508 | 1 | 1 | 2.8e-08 | 8.4e-06 | 6.8e-01 | 99 | NUDT18 |
16 | 8 | 141421996 | 142253369 | 1 | 1 | 1.9e-07 | 6.6e-07 | 8.7e-01 | 100 | PTK2 |
17 | 9 | 95502571 | 96898436 | 1 | 1 | 9.7e-08 | 3.9e-08 | 1.2e-05 | 37 | RP11-165J3.6 |
18 | 9 | 119768572 | 121177842 | 1 | 1 | 5.9e-10 | 2.3e-09 | 1.8e-02 | 84 | TLR4 |
19 | 11 | 12611333 | 14105497 | 1 | 1 | 6.6e-08 | 6.1e-07 | 8.0e-01 | 100 | ARNTL |
20 | 11 | 46010847 | 48559571 | 18 | 8 | 1.9e-15 | 6.0e-14 | NaN | NaN | ARHGAP1 C1QTNF4 LRP4 MADD NUP160 |
21 | 11 | 112135760 | 113969669 | 5 | 2 | 9.1e-14 | 1.8e-13 | 1.0e+00 | 100 | DRD2 RP11-159N11.4 |
22 | 12 | 109295508 | 110704487 | 2 | 1 | 4.3e-08 | 5.1e-09 | 3.9e-02 | 88 | MMAB |
23 | 13 | 66643767 | 68053176 | 1 | 1 | 2.3e-08 | 1.9e-06 | 1.1e-04 | 34 | PCDH9 |
24 | 14 | 74531485 | 76089054 | 3 | 1 | 1.0e-09 | 2.1e-10 | 6.6e-02 | 92 | DLST |
25 | 15 | 77207277 | 78806023 | 1 | 1 | 3.1e-07 | 3.8e-10 | 2.3e-05 | 54 | LINGO1 |
26 | 16 | 70624483 | 72022941 | 1 | 1 | 2.2e-07 | 2.3e-06 | 3.5e-01 | 96 | CMTR2 |
27 | 16 | 88523815 | 89030118 | 1 | 1 | 1.5e-07 | 9.9e-07 | 2.5e-01 | 94 | CTU2 |
28 | 17 | 42607368 | 45796313 | 20 | 1 | 1.1e-22 | 1.4e-21 | 9.3e-02 | 97 | WNT3 |
29 | 17 | 78843139 | 79380547 | 1 | 1 | 1.4e-07 | 4.0e-07 | 1.0e+00 | 100 | AATK |
30 | 18 | 34614002 | 35378540 | 1 | 1 | 1.1e-07 | 3.5e-12 | 5.6e-06 | 57 | CELF4 |
31 | 18 | 49172179 | 51753106 | 1 | 1 | 2.5e-08 | 3.9e-12 | 4.3e-06 | 56 | DCC |
32 | 18 | 52209411 | 54028036 | 1 | 1 | 1.9e-08 | 8.3e-17 | 8.1e-15 | 13 | TCF4 |
33 | 19 | 32151452 | 33668090 | 2 | 1 | 2.1e-11 | 1.1e-10 | 1.0e+00 | 100 | DPY19L3 |
34 | 20 | 43958786 | 45456440 | 2 | 2 | 9.4e-11 | 1.8e-11 | 1.0e+00 | 100 | CD40 SLC12A5 |
35 | 22 | 38388203 | 39770597 | 1 | 1 | 6.6e-08 | 1.9e-07 | 1.0e+00 | 100 | TOMM22 |
Trait | chisq ratio | # genes+ | # genes++ | % genes++ | corr | corr P | genes |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|---|---|---|---|
GTEx | Uterus | 7 | 1.23 | 2.9 |
GTEx | Small Intestine Terminal Ileum | 5 | 1.08 | 2.7 |
GTEx | Artery Coronary | 11 | 0.93 | 2.6 |
GTEx | Brain Hippocampus | 6 | 1.15 | 2.6 |
GTEx | Brain Hypothalamus | 6 | 1.02 | 2.6 |
GTEx | Ovary | 9 | 0.99 | 2.6 |
GTEx | Brain Cortex | 12 | 1.16 | 2.5 |
GTEx | Brain Frontal Cortex BA9 | 7 | 0.76 | 2.5 |
GTEx | Brain Putamen basal ganglia | 5 | 0.80 | 2.5 |
GTEx | Esophagus Gastroesophageal Junction | 14 | 0.97 | 2.5 |
GTEx | Prostate | 9 | 1.08 | 2.5 |
GTEx | Vagina | 5 | 0.79 | 2.5 |
GTEx | Brain Caudate basal ganglia | 10 | 1.08 | 2.4 |
GTEx | Brain Nucleus accumbens basal ganglia | 7 | 0.81 | 2.4 |
GTEx | Cells EBV-transformed lymphocytes | 13 | 0.92 | 2.4 |
GTEx | Skin Not Sun Exposed Suprapubic | 16 | 0.65 | 2.4 |
GTEx | Spleen | 12 | 0.85 | 2.4 |
The Cancer Genome Atlas | Esophageal Carcinoma | 4 | 0.59 | 2.4 |
GTEx | Adipose Visceral Omentum | 12 | 0.59 | 2.3 |
GTEx | Brain Cerebellar Hemisphere | 10 | 0.67 | 2.3 |
GTEx | Brain Cerebellum | 11 | 0.55 | 2.3 |
GTEx | Breast Mammary Tissue | 11 | 0.56 | 2.3 |
GTEx | Breast Mammary Tissue (Female) | 11 | 0.67 | 2.3 |
GTEx | Colon Sigmoid | 10 | 0.68 | 2.3 |
GTEx | Heart Left Ventricle | 9 | 0.59 | 2.3 |
GTEx | Liver | 6 | 0.84 | 2.3 |
GTEx | Pituitary | 8 | 0.72 | 2.3 |
GTEx | Skin Sun Exposed Lower leg | 18 | 0.50 | 2.3 |
GTEx | Stomach | 9 | 0.62 | 2.3 |
GTEx | Artery Aorta | 11 | 0.37 | 2.2 |
GTEx | Breast Mammary Tissue (Male) | 7 | 0.59 | 2.2 |
GTEx | Colon Transverse | 10 | 0.48 | 2.2 |
GTEx | Esophagus Mucosa | 16 | 0.48 | 2.2 |
GTEx | Esophagus Muscularis | 19 | 0.59 | 2.2 |
GTEx | Heart Atrial Appendage | 10 | 0.63 | 2.2 |
GTEx | Lung | 18 | 0.63 | 2.2 |
GTEx | Pancreas | 8 | 0.49 | 2.2 |
GTEx | Testis | 15 | 0.48 | 2.2 |
GTEx | Adipose Subcutaneous | 15 | 0.43 | 2.1 |
GTEx | Adrenal Gland | 7 | 0.48 | 2.1 |
GTEx | Artery Tibial | 14 | 0.37 | 2.1 |
GTEx | Cells Transformed fibroblasts | 21 | 0.50 | 2.1 |
GTEx | Muscle Skeletal | 11 | 0.38 | 2.1 |
GTEx | Thyroid | 16 | 0.40 | 2.1 |
GTEx | Whole Blood | 10 | 0.50 | 2.1 |
The Cancer Genome Atlas | Bladder Urothelial Carcinoma | 3 | 0.18 | 2.1 |
The Cancer Genome Atlas | Colon Adenocarcinoma | 4 | 0.19 | 2.1 |
The Cancer Genome Atlas | Glioblastoma Multiforme | 6 | 0.59 | 2.1 |
The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | 13 | 0.48 | 2.1 |
The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | 5 | 0.32 | 2.1 |
The Cancer Genome Atlas | Rectum Adenocarcinoma | 2 | 0.29 | 2.1 |
The Cancer Genome Atlas | Soft Tissue Sarcoma | 4 | 0.38 | 2.1 |
The Cancer Genome Atlas | Stomach Adenocarcinoma | 6 | 0.36 | 2.1 |
The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | 2 | 0.39 | 2.1 |
GTEx | Nerve Tibial | 13 | 0.30 | 2.0 |
NTR | Blood | 7 | 0.29 | 2.0 |
ROSMAP | Brain Pre-frontal Cortex | 13 | 0.30 | 2.0 |
CommonMind | Brain Pre-frontal Cortex | 10 | 0.19 | 2.0 |
The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | 3 | 0.27 | 2.0 |
The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | 6 | 0.29 | 2.0 |
The Cancer Genome Atlas | Lung Adenocarcinoma | 9 | 0.31 | 2.0 |
The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | 5 | 0.20 | 2.0 |
The Cancer Genome Atlas | Pancreatic Adenocarcinoma | 4 | 0.24 | 2.0 |
The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | 6 | 0.45 | 2.0 |
The Cancer Genome Atlas | Prostate Adenocarcinoma | 13 | 0.28 | 2.0 |
METSIM | Adipose | 12 | 0.26 | 1.9 |
The Cancer Genome Atlas | Breast Invasive Carcinoma | 10 | 0.23 | 1.9 |
The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | 12 | 0.29 | 1.9 |
The Cancer Genome Atlas | Brain Lower Grade Glioma | 13 | 0.30 | 1.9 |
The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | 5 | 0.45 | 1.9 |
The Cancer Genome Atlas | Thyroid Carcinoma | 13 | 0.25 | 1.9 |
YFS | Blood | 5 | 0.11 | 1.8 |
The Cancer Genome Atlas | Testicular Germ Cell Tumors | 4 | 0.31 | 1.8 |
The Cancer Genome Atlas | Skin Cutaneous Melanoma | 1 | 0.19 | 1.7 |