Best TWAS P=9.73e-08 · Best GWAS P=3.91e-08 conditioned to 1.24e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | RP11-165J3.6 | 0.22 | 0.20 | lasso | 2 | 0.19 | 4.9e-15 | 5.2 | 5.2 | 2.4e-07 | -0.22 | 0.04 | 0.96 | FALSE |
| 2 | GTEx | Breast Mammary Tissue (Female) | RP11-165J3.6 | 0.21 | 0.02 | lasso | 3 | 0.00 | 2.3e-01 | 5.2 | 5.1 | 2.8e-07 | -0.22 | 0.04 | 0.42 | FALSE |
| 3 | GTEx | Esophagus Gastroesophageal Junction | RP11-165J3.6 | 0.34 | 0.26 | lasso | 8 | 0.27 | 3.0e-10 | 5.2 | 5.2 | 2.0e-07 | -0.22 | 0.04 | 0.96 | FALSE |
| 4 | GTEx | Lung | RP11-165J3.6 | 0.25 | 0.16 | lasso | 7 | 0.17 | 4.1e-13 | 5.2 | 5.3 | 9.7e-08 | -0.23 | 0.04 | 0.95 | TRUE |
| 5 | GTEx | Thyroid | RP11-165J3.6 | 0.35 | 0.27 | lasso | 3 | 0.29 | 1.2e-22 | 5.2 | 5.2 | 1.5e-07 | -0.25 | 0.05 | 0.95 | FALSE |