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Depressed Affect (Nagel 2018)
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chr9:119,768,572-121,177,842
Best TWAS P=5.9e-10 · Best GWAS P=2.27e-09 conditioned to 0.0181
119.8M
120M
120.2M
120.4M
120.6M
120.8M
121M
121.2M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
NTR
Blood
TLR4
0.07
0.09
lasso
4
0.09
1.1e-26
5.8
-6.2
5.9e-10
-0.69
0.00
1.00
TRUE
3
YFS
Blood
TLR4
0.55
0.23
bslmm
565
0.39
9.2e-136
5.8
-5.6
2.2e-08
-0.48
0.00
1.00
FALSE
1
GTEx
Whole Blood
TLR4
0.13
0.14
lasso
2
0.13
9.8e-12
5.2
-5.2
1.5e-07
-0.65
0.02
0.98
FALSE