Best TWAS P=5.9e-10 · Best GWAS P=2.27e-09 conditioned to 0.0181
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Whole Blood | TLR4 | 0.13 | 0.14 | lasso | 2 | 0.13 | 9.8e-12 | 5.2 | -5.2 | 1.5e-07 | -0.65 | 0.02 | 0.98 | FALSE |
| 2 | NTR | Blood | TLR4 | 0.07 | 0.09 | lasso | 4 | 0.09 | 1.1e-26 | 5.8 | -6.2 | 5.9e-10 | -0.69 | 0.00 | 1.00 | TRUE |
| 3 | YFS | Blood | TLR4 | 0.55 | 0.23 | bslmm | 565 | 0.39 | 9.2e-136 | 5.8 | -5.6 | 2.2e-08 | -0.48 | 0.00 | 1.00 | FALSE |