Best TWAS P=8.17e-08 · Best GWAS P=3.26e-10 conditioned to 0.000149
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | PLCL2 | 0.10 | 0.06 | lasso | 5 | 0.09 | 4.5e-07 | 5.8 | 5.4 | 8.2e-08 | 0.61 | 0.21 | 0.79 | TRUE |
| 2 | GTEx | Skin Sun Exposed Lower leg | PLCL2 | 0.06 | 0.00 | enet | 1 | 0.00 | 5.0e-01 | 5.2 | 5.2 | 1.9e-07 | 0.78 | 0.06 | 0.66 | FALSE |
| 3 | METSIM | Adipose | PLCL2 | 0.08 | 0.03 | lasso | 6 | 0.04 | 2.3e-06 | 5.6 | 5.3 | 1.0e-07 | 0.69 | 0.15 | 0.85 | FALSE |