[Hub]/) : Traits : Depressed Affect (Nagel 2018) : ← →

chr3:16,154,636-17,814,553

Best TWAS P=8.17e-08 · Best GWAS P=3.26e-10 conditioned to 0.000149

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Cells Transformed fibroblasts	PLCL2	0.10	0.06	lasso	5	0.09	4.5e-07	5.8	5.4	8.2e-08	0.61	0.21	0.79	TRUE
3	METSIM	Adipose	PLCL2	0.08	0.03	lasso	6	0.04	2.3e-06	5.6	5.3	1.0e-07	0.69	0.15	0.85	FALSE
2	GTEx	Skin Sun Exposed Lower leg	PLCL2	0.06	0.00	enet	1	0.00	5.0e-01	5.2	5.2	1.9e-07	0.78	0.06	0.66	FALSE