TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Depressed Affect (Nagel 2018)
:
←
→
chr2:219,863,589-220,358,586
Best TWAS P=4.87e-08 · Best GWAS P=3.66e-07 conditioned to 0.0744
219.9M
220M
220.1M
220.2M
220.3M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Pancreatic Adenocarcinoma
GLB1L
0.19
0.06
enet
14
0.09
0.00020
4.6
-5.5
4.9e-08
-0.70
0
0.32
TRUE
1
The Cancer Genome Atlas
Brain Lower Grade Glioma
STK16
0.05
0.00
enet
10
0.03
0.00053
3.9
-5.2
1.6e-07
-0.77
0
0.22
FALSE