Best TWAS P=8.07e-08 · Best GWAS P=2.42e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Nucleus accumbens basal ganglia | COX4I2 | 0.13 | 0.14 | lasso | 5 | 0.05 | 0.022 | -4.9 | -5.2 | 1.8e-07 | 0.85 | 0.04 | 0.71 | FALSE |
| 2 | GTEx | Heart Left Ventricle | COX4I2 | 0.06 | 0.05 | lasso | 6 | 0.01 | 0.062 | -5.6 | -5.4 | 8.1e-08 | 0.96 | 0.02 | 0.97 | TRUE |