Hub : Genes

COX4I2

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.0920	0.0350	2.6e-06	0.107	NA	0.087	NA	0.106	4.3e-09	NA	1.3e-07	NA	5.3e-09
2	GTEx	Brain Caudate basal ganglia	0.2350	0.0930	3.7e-04	0.029	NA	0.009	NA	0.055	5.1e-02	NA	1.7e-01	NA	1.1e-02
3	GTEx	Brain Nucleus accumbens basal ganglia	0.1260	0.0600	3.4e-03	0.138	NA	-0.010	NA	0.046	1.6e-04	NA	7.7e-01	NA	2.2e-02
4	GTEx	Cells EBV-transformed lymphocytes	0.4970	0.1160	2.2e-03	-0.008	NA	0.025	NA	-0.004	7.0e-01	NA	5.2e-02	NA	4.8e-01
5	GTEx	Esophagus Gastroesophageal Junction	0.3720	0.1370	1.1e-03	-0.008	NA	0.016	NA	0.023	8.3e-01	NA	8.7e-02	NA	5.1e-02
6	GTEx	Esophagus Muscularis	0.0920	0.0350	1.1e-05	0.125	NA	0.090	NA	0.089	5.3e-08	NA	4.1e-06	NA	4.6e-06
7	GTEx	Heart Left Ventricle	0.0581	0.0288	2.0e-03	0.054	NA	0.013	NA	0.013	7.5e-04	NA	6.5e-02	NA	6.2e-02
8	GTEx	Lung	0.0477	0.0279	3.1e-03	0.014	NA	0.031	NA	0.022	2.5e-02	NA	1.8e-03	NA	8.2e-03
9	GTEx	Muscle Skeletal	0.1010	0.0349	4.7e-08	0.078	NA	0.087	NA	0.090	4.4e-08	NA	7.5e-09	NA	3.5e-09
10	GTEx	Nerve Tibial	0.1340	0.0481	7.4e-07	0.101	NA	0.065	NA	0.074	1.4e-07	NA	2.2e-05	NA	6.6e-06
11	GTEx	Skin Not Sun Exposed Suprapubic	0.0770	0.0340	9.4e-04	0.055	NA	0.034	NA	0.046	6.0e-04	NA	6.0e-03	NA	1.5e-03
12	GTEx	Skin Sun Exposed Lower leg	0.0320	0.0160	2.3e-03	0.045	NA	0.038	NA	0.038	1.3e-04	NA	3.7e-04	NA	3.8e-04
13	GTEx	Thyroid	0.0440	0.0230	3.1e-03	0.048	NA	0.027	NA	0.031	1.4e-04	NA	3.3e-03	NA	1.8e-03
14	GTEx	Vagina	0.1690	0.0860	2.8e-03	0.115	NA	0.093	NA	0.162	1.4e-03	NA	3.9e-03	NA	1.5e-04
15	ROSMAP	Brain Pre-frontal Cortex	0.1204	0.0427	4.3e-08	0.043	0.064	0.074	0.067	0.071	2.7e-06	1.3e-08	7.8e-10	5.4e-09	2.1e-09
16	TCGA	Bladder Urothelial Carcinoma	0.0600	0.0360	1.1e-04	0.024	0.040	0.024	NA	0.036	3.9e-03	2.6e-04	3.9e-03	NA	4.5e-04
17	TCGA	Breast Invasive Carcinoma	0.0838	0.0446	1.4e-11	0.065	0.061	0.065	NA	0.064	3.6e-13	1.6e-12	3.4e-13	NA	4.4e-13
18	TCGA	Esophageal Carcinoma	0.1670	0.0960	1.2e-03	0.073	0.100	0.049	NA	0.088	2.5e-03	4.5e-04	1.1e-02	NA	9.4e-04
19	TCGA	Kidney Renal Clear Cell Carcinoma	0.0647	0.0430	7.6e-05	0.028	0.029	0.020	NA	0.032	3.4e-04	2.9e-04	2.3e-03	NA	1.6e-04
20	TCGA	Lung Adenocarcinoma	0.0373	0.0214	7.2e-06	0.056	0.046	0.052	NA	0.051	3.8e-07	3.7e-06	9.8e-07	NA	1.2e-06
21	TCGA	Lung Squamous Cell Carcinoma	0.0392	0.0243	1.6e-05	0.034	0.039	0.034	NA	0.036	9.3e-05	2.5e-05	9.3e-05	NA	4.9e-05
22	TCGA	Prostate Adenocarcinoma	0.0695	0.0437	3.1e-07	0.073	0.064	0.064	NA	0.066	4.6e-08	3.0e-07	2.9e-07	NA	2.0e-07
23	TCGA	Stomach Adenocarcinoma	0.0890	0.0660	8.3e-03	0.026	0.028	0.017	NA	0.019	5.4e-03	3.8e-03	2.0e-02	NA	1.5e-02
24	TCGA	Testicular Germ Cell Tumors	0.0960	0.0560	2.7e-03	0.026	0.045	0.033	NA	0.029	4.0e-02	1.0e-02	2.5e-02	NA	3.4e-02
25	TCGA	Thyroid Carcinoma	0.0240	0.0180	4.3e-03	0.025	0.019	0.012	NA	0.027	1.5e-03	5.7e-03	2.3e-02	NA	1.0e-03

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25
Commuting to job workplace: Public transport	13.0	15.5	25.7	-4.4	-3.1	-4.4	-2.4	-4.6	-4.8	-4.7	-5.1	-4.6	-4.7	-4.1	-4.2	-3.9	-4.0	-2.4	-3.5	-0.0	-4.2	-3.8	-4.5	-4.3	-4.7	-2.0	-4.3
Blood Platelet Count	11.1	129.1	282.2	-10.0	-10.0	-11.2	-7.2	-11.8	-14.1	-11.1	-11.6	-9.5	-9.9	-11.7	-10.8	-12.4	-16.8	-13.1	-13.2	-8.8	-13.3	-9.4	-13.8	-12.0	-8.9	-12.3	-11.0
Mean Putamen Volume	10.5	12.0	28.8	-3.5	-1.1	-5.2	-2.1	-3.6	-5.4	-3.4	-3.6	-2.9	-4.5	-3.4	-3.2	-1.9	-2.4	-4.0	-3.3	-2.6	-4.2	-2.4	-4.6	-3.4	-3.6	-3.8	-3.3
Sitting height	8.2	58.0	89.7	7.7	6.3	8.0	6.8	8.4	9.4	9.0	8.9	8.2	9.5	8.5	8.1	6.4	7.0	6.3	7.0	2.3	8.6	7.7	9.2	8.4	7.2	6.1	8.1
Gout (self-reported)	7.3	10.1	16.4	-3.3	-2.9	-2.9	-1.9	-3.5	-3.1	-3.1	-3.5	-3.6	-2.6	-3.7	-3.5	-3.7	-3.3	-3.1	-4.1	-1.7	-3.7	-3.0	-3.6	-3.7	-2.7	-2.7	-3.5
Back pain experienced in last month	7.2	10.5	17.6	4.0	2.2	3.1	2.3	4.1	3.5	3.3	4.0	4.1	3.5	3.6	3.8	4.2	3.3	1.6	2.6	-0.3	3.5	3.0	3.4	3.6	4.0	1.3	3.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	6.6	13.9	21.4	-3.7	-2.5	-3.9	-2.8	-4.3	-4.5	-3.7	-4.6	-4.5	-4.5	-4.1	-4.2	-3.1	-3.5	-3.0	-3.5	-1.0	-4.4	-3.2	-4.4	-4.3	-4.1	-2.7	-4.2
Blood Red Count	6.5	62.6	104.0	-9.3	-8.3	-10.2	-4.3	-9.3	-8.9	-10.1	-9.4	-8.3	-9.3	-8.8	-8.7	-8.2	-5.3	-4.3	-6.5	0.3	-8.4	-9.1	-8.8	-8.8	-7.9	-4.2	-8.8
Medication: Ventolin 100micrograms inhaler	6.2	8.0	16.5	2.9	1.5	2.3	1.9	3.0	2.8	3.0	3.2	3.3	2.9	3.4	3.2	1.8	1.6	3.1	4.1	1.9	3.5	2.9	3.4	3.4	2.4	2.7	3.2
Lung FVC	6.1	31.0	49.1	-4.6	-3.6	-5.3	-3.6	-5.8	-7.0	-5.2	-5.8	-5.6	-5.7	-6.0	-5.6	-4.7	-6.5	-7.0	-6.6	-4.9	-6.9	-4.2	-7.0	-6.2	-4.5	-6.5	-5.6
Commuting to job workplace: Car/motor vehicle	5.9	6.8	11.6	3.3	1.3	3.1	1.5	3.1	3.4	3.3	3.1	2.8	3.2	2.7	3.0	2.1	1.9	1.6	2.2	0.2	3.0	2.2	3.0	2.8	3.4	1.4	3.0
Loneliness, isolation	4.9	6.8	10.5	2.2	2.6	2.2	1.7	2.7	2.8	2.4	3.1	2.7	2.6	2.9	2.7	2.4	3.1	2.9	3.2	1.8	3.0	2.4	3.1	3.0	2.0	2.7	2.7
Medication: Blood pressure	4.8	8.4	18.2	-4.3	-2.2	-4.3	-1.3	-3.6	-3.0	-3.1	-2.9	-3.1	-3.7	-3.6	-3.9	-2.5	-0.2	-1.0	-2.4	0.5	-3.2	-2.8	-2.8	-3.2	-3.6	-0.9	-3.6
Hearing difficulty/problems: Yes	4.7	7.2	10.9	3.0	3.0	2.6	1.0	3.3	2.8	3.1	3.1	3.1	3.2	3.1	3.1	2.8	2.8	1.2	2.0	-0.4	3.0	3.0	2.9	3.1	2.9	1.2	3.2
Hypertension (Self-reported)	4.6	12.8	21.6	-4.5	-2.6	-4.4	-3.2	-4.4	-3.4	-4.0	-3.6	-4.1	-3.7	-4.4	-4.6	-4.1	-2.5	-1.5	-3.2	0.3	-4.0	-3.7	-3.4	-4.1	-4.0	-1.4	-4.5
Medication: Gliclazide	4.6	5.2	9.6	-2.4	-2.0	-2.6	-1.2	-2.7	-2.7	-2.9	-2.1	-2.3	-3.1	-2.7	-2.7	-1.5	-1.5	-1.7	-1.9	-0.8	-2.8	-2.3	-2.6	-2.7	-2.1	-1.9	-2.8
High blood pressure	4.5	12.6	20.6	-4.4	-3.0	-4.4	-2.9	-4.3	-3.4	-4.1	-3.6	-3.9	-3.8	-4.4	-4.5	-4.0	-2.3	-1.5	-3.1	0.3	-3.9	-3.9	-3.5	-4.1	-3.8	-1.4	-4.4
Vascular/heart problems diagnosed by doctor	4.4	12.0	20.6	4.3	3.1	4.3	2.8	4.3	3.1	4.1	3.5	3.7	3.7	4.3	4.5	4.0	2.1	1.3	3.0	-0.5	3.8	3.8	3.3	4.0	3.7	1.2	4.3
Illnesses of father: None of the above (group 1)	4.2	5.2	9.3	2.4	1.0	2.7	1.3	2.6	3.0	2.7	2.4	2.3	2.5	2.5	2.3	2.2	2.1	2.3	2.3	1.3	2.7	1.9	2.8	2.5	2.2	2.2	2.4
Age started oral contraceptive pill	4.2	5.3	13.8	-2.0	-1.8	-1.6	-1.9	-2.5	-2.3	-2.4	-2.5	-2.3	-2.0	-2.6	-2.3	-3.4	-3.7	-2.1	-2.8	-1.1	-2.5	-2.3	-2.5	-2.4	-1.9	-1.8	-2.3
Diastolic blood pressure, automated reading	4.2	13.1	25.6	-3.8	-4.7	-3.8	-0.8	-4.3	-3.2	-4.5	-3.7	-4.1	-4.1	-4.5	-4.3	-4.3	-2.6	-1.6	-3.3	0.3	-3.9	-5.1	-3.7	-4.3	-2.9	-1.7	-4.3
Medication: Allopurinol	4.1	5.5	9.4	-2.1	-2.8	-1.7	-0.8	-2.6	-2.0	-2.4	-2.5	-2.5	-1.7	-2.8	-2.6	-3.0	-2.6	-2.4	-3.1	-1.5	-2.7	-2.4	-2.6	-2.8	-1.5	-2.2	-2.5
Medication for pain relief, constipation, heartburn	3.9	6.7	10.1	2.5	2.3	3.0	1.4	2.8	3.0	3.0	2.1	2.3	3.0	3.2	2.8	2.7	2.5	2.6	2.8	1.8	3.1	2.8	3.0	2.9	1.5	2.8	2.8
Heel T-Score	3.8	30.0	51.4	7.2	5.4	5.6	3.5	6.7	5.0	7.0	6.9	6.2	6.0	6.1	6.5	6.3	4.1	1.7	4.8	-1.8	5.4	6.3	5.4	6.2	6.3	1.1	6.5
Cardiovascular Disease	3.8	12.6	20.4	-4.2	-3.1	-4.5	-2.7	-4.2	-3.8	-4.3	-3.5	-3.5	-3.8	-4.4	-4.4	-3.7	-2.0	-2.6	-3.4	-1.0	-4.1	-3.5	-3.8	-4.2	-3.2	-2.5	-4.2
Falls in the last year	3.7	5.0	9.4	-2.4	-1.2	-2.3	-2.4	-2.3	-2.0	-2.5	-2.0	-2.7	-2.5	-2.8	-2.7	-0.9	-0.2	-2.3	-3.1	-1.6	-2.7	-2.5	-2.5	-2.8	-1.2	-2.3	-2.7
Seen a psychiatrist for nerves, anxiety, tension or depression	3.7	4.9	7.0	-2.5	-1.5	-2.0	-1.8	-2.5	-2.4	-2.5	-2.2	-2.3	-2.5	-2.6	-2.6	-2.2	-2.3	-1.9	-2.4	-1.0	-2.6	-2.0	-2.4	-2.5	-2.2	-1.6	-2.6
Respiratory disease	3.6	8.1	15.9	2.9	2.8	2.0	1.2	2.9	2.7	3.1	2.7	2.9	2.8	3.4	3.0	1.8	2.4	3.4	4.0	2.4	3.5	3.2	3.4	3.4	1.5	3.3	3.1
Medication: Paracetamol	3.6	5.9	9.4	-2.2	-2.6	-2.9	-1.4	-2.7	-2.7	-2.8	-2.3	-2.3	-2.8	-2.9	-2.6	-2.7	-2.1	-2.2	-2.4	-1.3	-2.7	-3.1	-2.9	-2.7	-1.2	-2.4	-2.6
Exposure to tobacco smoke outside home	3.6	4.8	9.6	-1.9	-1.0	-2.2	-3.1	-2.5	-2.4	-2.6	-2.1	-2.0	-1.6	-2.5	-2.4	-2.8	-2.3	-2.2	-2.6	-1.4	-2.6	-1.7	-2.4	-2.4	-1.9	-2.0	-2.3
Asthma (self-reported)	3.6	7.2	12.3	2.5	2.0	2.2	0.6	2.7	3.1	2.8	2.7	2.6	2.8	3.0	2.5	1.6	2.5	3.5	3.5	2.5	3.3	2.8	3.5	3.0	1.5	3.4	2.7
Maternal smoking around birth	3.5	5.0	12.7	-2.6	-2.8	-2.1	-2.0	-2.4	-1.7	-3.2	-2.0	-2.0	-2.2	-2.7	-2.4	-3.2	-2.2	-1.2	-2.0	-0.1	-2.1	-3.6	-2.3	-2.5	-0.7	-1.5	-2.3
Hearing difficulty/problems with background noise	3.5	5.5	9.2	2.7	2.5	1.9	0.3	2.6	2.1	2.1	2.3	2.8	2.2	2.9	2.7	2.5	2.8	2.1	3.0	1.2	2.8	2.4	2.5	2.8	1.9	2.0	2.8
Asthma	3.5	7.0	11.6	2.6	2.0	2.4	0.5	2.8	3.1	2.9	2.7	2.7	3.0	2.9	2.6	1.7	2.2	3.1	3.3	2.1	3.2	2.9	3.4	3.0	1.7	3.1	2.8
Smoking Status	3.4	8.2	17.2	2.9	2.6	2.3	1.8	3.1	3.0	3.5	3.5	4.1	3.9	3.3	3.1	2.2	2.9	1.7	2.6	0.0	3.0	3.7	3.2	3.2	2.4	1.7	3.1
High cholesterol (Self-reported)	3.4	6.0	9.1	-2.4	-2.7	-3.0	-0.6	-2.6	-2.9	-3.0	-2.2	-2.1	-2.8	-2.8	-2.6	-2.2	-1.5	-2.7	-2.7	-1.9	-3.0	-2.5	-3.0	-2.7	-1.4	-2.8	-2.6
Fractured/broken bones in last 5 years	3.4	4.4	11.5	-2.3	-1.0	-2.3	-3.4	-2.4	-2.2	-2.3	-2.4	-2.3	-2.2	-2.2	-2.4	-1.7	-2.0	-1.4	-2.2	-0.4	-2.3	-1.7	-2.2	-2.3	-2.4	-1.1	-2.3
Ever used hormone-replacement therapy (HRT)	3.3	4.2	9.7	1.5	1.8	1.6	0.4	1.9	2.7	1.6	1.9	1.7	2.0	2.1	1.7	1.4	2.2	3.1	2.5	2.5	2.5	1.8	2.8	2.2	0.9	3.1	1.8
Length of working week for main job	3.3	3.7	7.7	-2.8	-1.4	-1.9	-1.2	-2.4	-1.7	-2.4	-1.9	-1.9	-2.0	-2.5	-2.6	-2.0	-0.9	-0.8	-1.9	0.1	-2.2	-2.0	-1.8	-2.4	-2.0	-0.7	-2.5
Ever highly irritable/argumentative for 2 days	3.3	4.0	6.5	1.9	2.2	1.9	0.6	1.9	2.2	1.7	2.0	2.0	1.9	2.2	1.9	1.7	2.6	2.5	2.3	1.8	2.3	2.0	2.5	2.1	0.9	2.5	1.8
Medication for cholesterol, blood pressure or diabetes	3.3	5.5	11.9	3.4	1.9	3.5	0.8	2.8	2.4	2.8	2.1	2.3	3.1	3.0	3.1	1.7	-0.1	1.1	2.0	0.1	2.7	2.4	2.3	2.6	2.5	1.2	2.9
Average weekly red wine intake	3.1	4.6	6.6	-2.4	-1.3	-2.1	-1.1	-2.5	-2.5	-2.6	-2.2	-2.5	-2.3	-2.3	-2.3	-2.3	-2.3	-1.8	-2.3	-0.9	-2.5	-1.7	-2.4	-2.4	-2.4	-1.5	-2.4
HDL Cholesterol	3.0	5.0	8.4	2.5	2.5	2.3	0.8	2.6	2.2	2.7	2.7	2.4	2.9	2.5	2.5	2.2	1.4	1.4	2.3	0.2	2.5	2.6	2.4	2.6	2.2	1.3	2.6
Systolic Blood Pressure	3.0	15.0	28.4	-3.6	-5.3	-3.4	-1.4	-4.0	-3.4	-4.4	-3.4	-3.9	-3.9	-5.0	-4.4	-3.5	-3.2	-3.7	-4.8	-2.3	-4.5	-5.3	-4.3	-4.6	-1.5	-3.9	-4.2
Serious illness, injury or assault to yourself	2.9	3.5	5.7	-2.4	-1.4	-2.1	-1.8	-2.3	-1.8	-2.0	-1.8	-1.7	-1.6	-2.2	-2.3	-2.4	-2.0	-1.5	-1.8	-0.8	-2.2	-1.4	-1.9	-2.2	-1.6	-1.4	-2.2
Mouth/teeth dental problems: Loose teeth	2.9	3.5	11.2	1.8	0.2	1.6	3.4	2.0	2.0	1.6	2.1	2.3	1.5	1.8	2.0	1.4	2.4	1.7	2.2	0.9	2.1	1.0	2.0	2.0	2.2	1.3	2.0
Heel bone mineral density (BMD) T-score, automated (left)	2.7	6.0	12.0	3.5	1.2	2.6	1.6	3.0	2.4	2.8	2.8	3.1	2.5	2.8	3.0	2.9	2.1	1.1	2.5	-0.3	2.6	2.4	2.4	2.7	3.0	0.7	2.9
Wheeze or whistling in the chest in last year	2.7	4.8	11.7	0.9	1.1	1.3	2.1	1.8	2.6	1.7	2.1	1.9	2.0	2.2	1.8	1.2	3.3	3.4	3.0	2.9	2.6	1.7	2.8	2.2	1.0	3.3	1.8
Eye problems/disorders: Cataract	2.7	3.1	5.0	1.4	1.3	2.1	0.9	1.9	2.0	1.7	1.4	1.6	1.5	2.1	1.9	1.8	2.0	2.1	2.1	1.6	2.2	1.7	2.1	2.0	0.9	2.2	1.9
Frequency of unenthusiasm / disinterest in last 2 weeks	2.6	3.5	7.3	1.9	2.6	1.8	0.2	2.0	2.2	2.3	2.7	1.8	2.1	1.8	1.7	2.1	2.2	1.3	1.4	0.1	1.9	2.2	2.3	2.0	1.7	1.3	1.8
Triglycerides	2.5	4.1	12.0	-2.4	-3.5	-1.7	0.3	-2.3	-1.7	-2.6	-2.1	-2.2	-2.8	-2.4	-2.2	-1.8	-0.5	-0.7	-1.8	0.4	-2.0	-3.2	-2.0	-2.3	-1.2	-0.9	-2.2
Heel bone mineral density (BMD) T-score, automated (right)	2.5	5.7	13.4	3.3	0.2	2.9	2.1	3.0	2.5	2.7	2.7	2.9	2.6	2.5	3.0	2.8	1.7	0.6	1.9	-0.8	2.4	1.8	2.1	2.5	3.7	0.1	2.9
Exposure to tobacco smoke at home	2.5	2.8	5.1	-2.0	-1.3	-1.5	-2.3	-2.0	-1.5	-2.1	-1.8	-1.8	-1.4	-2.0	-2.0	-2.1	-1.2	-1.0	-1.7	-0.1	-1.8	-1.6	-1.6	-1.9	-1.7	-0.8	-2.0
Breast cancer (self-reported)	2.5	2.9	6.7	-1.2	-0.8	-2.5	-1.9	-1.7	-2.6	-1.8	-1.8	-1.1	-1.8	-1.5	-1.4	-1.3	-2.1	-2.1	-1.6	-1.4	-2.0	-1.1	-2.3	-1.7	-1.4	-2.1	-1.5
Medication: Paracetamol	2.4	3.7	8.0	-1.8	-2.1	-2.4	-1.4	-2.1	-1.9	-2.4	-1.7	-1.7	-2.0	-2.3	-1.9	-2.8	-1.8	-1.6	-1.7	-0.8	-2.0	-2.6	-2.2	-2.1	-0.5	-1.8	-1.9
Medication: Simvastatin	2.3	3.3	7.3	-2.0	-2.0	-2.7	0.1	-2.2	-2.2	-2.4	-1.8	-1.7	-2.6	-2.0	-2.0	-1.9	-1.2	-0.7	-1.3	0.2	-1.9	-2.1	-1.9	-1.9	-1.9	-0.8	-2.0
Alcohol intake versus 10 years previously	2.2	3.3	6.9	-1.9	-2.5	-1.0	-2.1	-1.9	-1.4	-2.2	-1.8	-1.9	-1.7	-2.2	-1.9	-2.1	-1.6	-1.5	-1.9	-0.7	-1.9	-2.6	-2.0	-2.2	-0.5	-1.7	-1.9
Reason for reducing amount of alcohol drunk: Health precaution	2.2	2.5	4.8	-2.0	-1.3	-1.5	-0.0	-2.0	-1.4	-1.8	-1.6	-2.2	-1.7	-2.0	-2.1	-1.6	-1.4	-1.0	-1.7	-0.3	-1.9	-1.4	-1.6	-1.9	-1.7	-0.9	-2.0
Family relationship satisfaction	2.1	2.6	4.1	1.6	1.6	1.5	0.3	1.8	2.0	1.8	2.0	1.7	2.0	1.7	1.6	1.4	1.6	1.3	1.5	0.5	1.9	1.6	2.0	1.8	1.6	1.3	1.7
Eye problems/disorders: Glaucoma	2.1	2.4	4.5	-1.5	0.3	-1.7	-1.2	-1.6	-2.1	-1.3	-1.3	-1.6	-1.2	-1.6	-1.8	-1.3	-2.0	-1.9	-1.9	-1.5	-2.0	-0.5	-1.7	-1.6	-1.8	-1.6	-1.6
Alzheimer’s Disease (in mother)	2.0	2.3	5.4	-1.4	-0.4	-1.1	-0.9	-1.5	-1.8	-1.4	-1.7	-2.1	-1.2	-1.5	-1.4	-1.2	-1.1	-2.0	-2.3	-1.5	-1.9	-1.2	-1.8	-1.7	-1.3	-1.7	-1.5
Systolic blood pressure, automated reading	2.0	5.9	19.7	-2.2	-4.4	-1.6	0.4	-2.6	-1.6	-2.9	-2.1	-2.6	-2.4	-3.2	-2.8	-2.7	-2.1	-1.4	-2.6	-0.4	-2.5	-4.0	-2.4	-2.9	-0.8	-1.7	-2.7
Supplements: Zinc	2.0	2.1	3.5	-1.6	-1.7	-1.7	-1.8	-1.6	-1.4	-1.9	-1.8	-1.1	-1.7	-1.7	-1.7	-1.1	-0.6	-1.0	-1.4	-0.2	-1.6	-1.5	-1.6	-1.7	-1.5	-0.9	-1.7
Illness, injury, bereavement, stress in last 2 years	2.0	2.4	4.5	2.1	2.0	1.4	1.2	1.9	1.2	1.9	1.9	1.7	1.9	1.9	2.0	1.3	0.2	0.3	1.0	-0.7	1.5	2.0	1.5	1.9	1.4	0.3	2.0
Cholesterol lowering medication	2.0	3.0	5.6	-1.8	-1.7	-2.4	-1.0	-2.2	-2.1	-2.3	-1.7	-1.8	-2.0	-2.0	-2.0	-2.1	-1.4	-0.8	-1.1	0.1	-1.9	-1.9	-1.8	-1.9	-1.7	-0.9	-2.1
Average weekly spirits intake	1.9	2.3	6.4	-1.6	-1.4	-2.5	-1.3	-1.7	-1.8	-2.0	-1.6	-1.1	-1.9	-1.7	-1.7	-1.4	-0.9	-1.0	-1.1	-0.2	-1.6	-1.6	-1.8	-1.6	-1.3	-1.1	-1.6
Depressed Affect (Nagel 2018)	1.8	3.9	8.9	1.8	2.5	1.3	1.8	2.1	1.8	2.3	2.6	2.4	2.2	2.1	1.9	1.6	3.0	1.3	2.0	0.2	2.0	2.3	2.2	2.1	1.5	1.3	2.0
Had other major operations	1.8	2.2	4.0	-1.5	-1.2	-1.8	-1.3	-1.9	-1.5	-1.6	-2.0	-1.4	-1.7	-1.5	-1.7	-1.7	-1.6	-0.6	-1.2	0.3	-1.6	-1.4	-1.6	-1.7	-1.9	-0.5	-1.7
Tinnitus: Yes, now most or all of the time	1.8	2.1	5.7	0.8	1.8	0.9	0.3	1.0	1.5	1.4	0.9	1.0	0.6	1.5	1.0	1.7	2.0	2.3	2.0	2.1	1.5	1.6	1.8	1.4	-0.2	2.4	1.0
Medication: Lisinopril	1.8	2.4	5.9	-0.8	-1.7	-1.5	-0.3	-1.3	-1.8	-1.2	-0.8	-0.9	-1.5	-1.9	-1.4	-1.0	-1.6	-2.3	-2.2	-2.2	-1.9	-1.6	-1.8	-1.5	-0.3	-2.4	-1.3
Alzheimer’s Disease (including proxy)	1.7	2.4	6.6	-1.4	-0.6	-1.7	-0.1	-1.5	-2.6	-1.5	-1.7	-1.8	-1.2	-1.5	-1.3	-1.3	-1.2	-2.1	-1.9	-1.4	-1.8	-1.4	-2.1	-1.6	-1.6	-1.8	-1.5
Pain all over the body in last month	1.7	1.9	3.3	-1.6	-1.0	-1.8	-1.6	-1.6	-1.6	-1.8	-1.4	-1.1	-1.7	-1.5	-1.5	-1.7	-1.1	-0.7	-0.9	-0.0	-1.5	-1.3	-1.5	-1.4	-1.4	-0.8	-1.5
Fed-up feelings	1.6	2.9	7.1	1.6	2.7	1.0	0.5	1.9	1.4	2.2	2.3	2.4	2.1	1.7	1.7	1.9	2.2	0.6	1.3	-0.6	1.5	2.3	1.8	1.9	1.3	0.6	1.8
Medication: Atenolol	1.6	2.0	6.9	-1.3	-2.6	-1.6	-0.4	-1.7	-1.2	-2.0	-1.5	-1.3	-1.5	-1.7	-1.8	-1.5	-0.9	0.1	-0.6	1.0	-1.3	-1.9	-1.2	-1.5	-1.5	-0.1	-1.7
Mouth/teeth dental problems: Dentures	1.6	2.7	7.5	1.1	0.7	1.8	1.5	1.3	2.7	1.6	1.8	1.5	2.1	1.3	1.2	-0.3	1.7	2.4	1.5	1.8	1.9	0.8	2.4	1.4	1.4	2.3	1.2
Standing height	1.6	16.1	29.9	4.0	2.7	4.7	4.3	4.4	5.5	4.9	4.8	4.4	5.5	4.3	4.4	2.4	2.8	3.1	2.9	0.8	4.6	3.5	4.9	4.3	4.4	3.0	4.3
Birth weight of first child	1.6	3.0	6.1	-2.0	-1.2	-1.3	-2.1	-2.0	-1.6	-2.1	-2.3	-1.8	-1.7	-1.7	-1.7	-2.5	-2.0	-0.7	-1.9	0.4	-1.6	-1.9	-1.8	-1.8	-2.1	-0.4	-1.8
Illnesses of father: Heart disease	1.6	2.2	3.6	-1.6	-0.5	-1.7	-1.8	-1.8	-1.7	-1.8	-1.6	-1.5	-1.4	-1.6	-1.6	-1.9	-1.6	-1.0	-1.3	-0.3	-1.6	-1.4	-1.7	-1.6	-1.4	-1.0	-1.6
Mother’s age at death	1.6	2.0	4.3	1.6	1.0	2.1	1.4	1.6	1.5	1.7	1.4	1.5	1.8	1.7	1.7	1.5	0.4	0.5	1.3	-0.2	1.4	1.5	1.4	1.5	1.6	0.5	1.6
Depression (Nagel 2018)	1.5	2.2	4.8	1.7	1.8	1.4	1.0	1.7	1.8	1.9	2.2	1.8	1.9	1.4	1.4	1.4	1.5	0.4	0.7	-0.7	1.4	1.7	1.6	1.5	1.8	0.4	1.5
Breast Cancer	1.5	3.5	5.8	1.3	1.7	2.3	0.8	1.9	2.4	2.2	1.7	1.6	2.4	2.1	1.9	2.1	2.2	2.0	1.4	1.3	2.1	1.9	2.4	2.0	0.9	2.3	1.8
Medication: Metformin	1.5	2.1	7.1	-1.5	-2.7	-1.5	0.8	-1.5	-1.5	-1.9	-1.3	-1.2	-2.0	-1.7	-1.5	-0.7	-0.0	-0.8	-0.9	-0.1	-1.5	-2.2	-1.7	-1.7	-0.6	-1.2	-1.6
Illnesses of mother	1.5	1.9	3.7	1.7	1.6	1.5	1.1	1.7	0.9	1.7	1.6	1.8	1.6	1.5	1.7	1.9	0.9	-0.3	0.5	-1.2	1.1	1.6	1.0	1.5	1.5	-0.2	1.6
Illnesses of siblings: Diabetes	1.5	1.9	3.9	-1.3	-1.6	-1.6	-1.1	-1.5	-1.2	-1.7	-1.3	-1.4	-1.2	-1.7	-1.5	-2.0	-0.9	-1.0	-1.4	-0.4	-1.5	-1.8	-1.5	-1.6	-0.7	-1.1	-1.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.5	1.8	3.0	-1.2	-0.0	-1.4	-1.6	-1.4	-1.4	-1.6	-1.0	-1.7	-1.2	-1.5	-1.5	-1.1	-0.7	-1.4	-1.6	-1.0	-1.7	-1.1	-1.5	-1.6	-1.2	-1.3	-1.6
Wears glasses or contact lenses	1.5	1.7	3.2	1.1	1.1	1.7	1.1	1.3	1.8	1.0	1.4	1.1	1.2	1.3	1.1	1.1	1.7	1.7	1.3	1.2	1.5	1.1	1.7	1.3	0.8	1.7	1.1
Hearing aid user	1.5	1.7	3.6	1.6	0.4	1.4	1.0	1.7	1.4	1.4	1.6	1.6	1.1	1.4	1.7	1.3	1.6	0.4	1.0	-0.3	1.6	0.9	1.2	1.6	1.9	0.4	1.7
Myopia	1.5	2.2	7.0	-2.2	-0.0	-1.8	-1.7	-1.9	-1.2	-1.1	-1.6	-1.7	-1.6	-1.4	-2.0	-1.8	-1.4	0.6	-0.2	1.6	-1.2	-0.7	-0.9	-1.4	-2.6	0.8	-1.8
Blood Eosinophil Count	1.4	11.0	25.9	-4.2	-1.4	-5.1	-2.1	-4.1	-4.3	-3.7	-3.5	-3.0	-3.8	-3.6	-3.8	-3.9	-1.0	-2.2	-2.9	-0.5	-3.8	-2.8	-3.7	-3.6	-3.9	-2.0	-3.8
Height	1.4	26.0	45.7	5.3	3.2	6.0	4.9	5.8	6.8	6.1	6.2	5.8	6.4	5.5	5.6	3.9	3.9	3.9	4.2	1.1	5.8	4.5	6.1	5.5	5.7	3.7	5.5
Sensitivity / hurt feelings	1.4	2.4	4.3	1.4	1.8	1.6	1.6	1.5	1.4	2.1	1.9	1.9	1.8	1.7	1.4	1.3	0.6	1.3	1.9	0.5	1.6	1.9	1.7	1.7	1.1	1.1	1.5
Had menopause	1.4	1.8	6.4	-1.6	-2.0	-0.4	-0.1	-1.5	-0.4	-1.8	-1.1	-1.2	-1.2	-1.6	-1.5	-2.5	-1.8	-0.2	-1.1	0.4	-1.2	-2.3	-1.0	-1.5	-0.4	-0.4	-1.5
Breastfed as a baby	1.4	1.7	5.1	-0.7	-0.3	-1.2	-1.2	-0.9	-1.7	-1.0	-1.4	-1.3	-1.2	-1.1	-1.0	-0.2	-1.4	-2.3	-1.7	-1.9	-1.6	-0.7	-1.8	-1.3	-0.8	-2.0	-1.0
Chronic bronchitis/emphysema (mother)	1.4	1.7	2.9	-1.7	-1.0	-1.5	-0.5	-1.6	-1.4	-1.6	-1.2	-1.3	-1.5	-1.5	-1.5	-1.7	-1.5	-0.6	-1.1	-0.1	-1.4	-1.4	-1.3	-1.4	-1.3	-0.7	-1.5
Pulse rate, automated reading	1.4	4.6	10.8	-2.8	-1.0	-3.2	-2.3	-2.8	-2.1	-2.5	-2.7	-2.0	-2.2	-2.0	-2.6	-2.5	-1.2	0.1	-0.7	1.6	-2.0	-1.7	-1.9	-2.3	-3.3	0.2	-2.7
Medication: Blood pressure	1.4	2.6	4.3	-1.2	-1.5	-1.6	-1.8	-1.8	-1.5	-2.0	-1.3	-2.1	-1.4	-2.1	-2.0	-1.5	-1.8	-1.1	-1.6	-0.4	-1.9	-1.9	-1.6	-1.9	-1.2	-1.1	-2.0
Commuting to job workplace: Cycle	1.4	1.7	2.9	-1.0	-1.5	-1.0	-0.4	-1.2	-1.4	-1.3	-1.4	-1.4	-1.2	-1.4	-1.2	-1.3	-1.0	-1.7	-1.6	-1.2	-1.4	-1.6	-1.7	-1.5	-0.3	-1.7	-1.2
Mouth/teeth dental problems	1.3	2.0	5.4	-0.2	-1.2	-0.5	-2.0	-0.8	-1.7	-1.4	-1.4	-1.6	-1.3	-1.2	-0.9	0.0	-2.2	-2.3	-1.9	-1.9	-1.5	-1.1	-1.9	-1.2	-0.4	-2.2	-0.9
Health satisfaction	1.3	1.7	4.5	0.9	1.4	1.3	1.2	1.1	1.9	1.7	1.9	1.2	1.2	1.0	0.8	0.9	2.1	1.5	1.3	0.8	1.3	1.4	1.8	1.2	0.9	1.4	0.9
Illnesses of father: High blood pressure	1.3	1.6	4.4	-1.5	-0.6	-2.1	-1.7	-1.3	-1.6	-1.5	-1.3	-1.2	-1.8	-1.4	-1.4	0.1	-0.1	-0.9	-0.9	-0.2	-1.4	-1.1	-1.5	-1.3	-1.4	-0.9	-1.4
Major Depression (MDD)	1.2	1.4	2.6	-1.2	-1.4	-1.1	0.2	-1.4	-1.2	-1.2	-1.3	-1.4	-1.2	-1.3	-1.6	-1.2	-0.3	-1.4	-0.9	-1.0	-1.3	-1.4	-1.3	-1.4	-0.8	-1.3	-1.5
Pulse wave Arterial Stiffness index	1.2	1.3	3.9	1.4	1.0	1.6	2.0	1.3	1.3	1.4	1.6	1.0	1.6	1.2	1.3	0.7	1.0	0.1	0.4	-0.8	0.9	1.1	1.2	1.0	1.6	0.1	1.1
Eye problems/disorders: None of the above	1.2	1.4	3.1	-0.8	-0.6	-1.5	-1.6	-1.3	-1.4	-1.2	-1.4	-1.2	-1.3	-1.2	-1.2	-1.1	-1.8	-1.0	-1.1	-0.3	-1.3	-0.8	-1.3	-1.2	-1.4	-0.8	-1.2
Emphysema/chronic bronchitis	1.2	1.4	3.9	1.1	0.8	0.4	1.4	1.3	0.5	1.0	1.2	2.0	1.1	1.6	1.7	0.2	1.4	0.7	1.6	0.2	1.4	1.2	0.9	1.5	1.0	0.6	1.5
Ever had stillbirth, spontaneous miscarriage or termination	1.2	1.3	2.8	-1.5	-1.2	-1.1	-0.4	-1.3	-1.1	-1.3	-1.2	-1.1	-1.1	-1.4	-1.4	-0.9	-0.7	-1.0	-1.7	-0.5	-1.3	-1.0	-1.2	-1.4	-1.3	-0.7	-1.3
Medication: Omeprazole (e.g. Zanprol)	1.2	1.5	4.3	-0.7	-1.3	-0.9	-1.2	-1.2	-1.1	-1.4	-0.7	-0.4	-1.0	-1.4	-1.1	-1.9	-2.1	-1.3	-1.2	-1.1	-1.4	-1.4	-1.3	-1.3	-0.1	-1.5	-1.2
Bipolar Disorder (2011)	1.1	1.1	2.4	1.3	1.2	0.6	0.0	1.2	0.5	1.4	1.2	1.6	0.9	1.4	0.0	1.1	1.1	0.3	1.3	-0.3	1.1	1.5	0.9	1.3	0.9	0.2	1.3
Pack years adult smoking proportion	1.1	1.7	5.9	0.8	0.7	0.3	-0.1	0.9	0.9	0.6	0.4	1.2	0.7	1.5	1.1	1.1	2.1	2.3	2.1	2.4	1.5	1.1	1.4	1.3	-0.5	2.4	1.0
Average weekly fortified wine intake	1.1	1.3	3.0	1.4	1.5	0.9	0.6	1.2	0.6	1.7	1.1	1.5	1.1	1.3	1.4	1.0	-0.4	-0.1	0.9	-0.8	1.0	1.7	0.9	1.4	1.0	-0.1	1.5
Medication: Ibuprofen (e.g. Nurofen)	1.1	1.4	6.4	-0.4	-0.6	-1.2	-0.1	-0.6	-1.6	-0.7	-0.4	-0.4	-0.8	-0.9	-0.6	-0.4	-1.1	-2.4	-2.1	-2.5	-1.4	-0.6	-1.4	-0.9	-0.0	-2.3	-0.6
Qualifications: O levels/GCSEs or equivalent	1.1	1.7	3.5	-1.1	-0.6	-1.0	-0.6	-1.3	-1.9	-1.4	-1.3	-1.4	-1.4	-1.2	-1.1	-1.5	-1.7	-1.8	-1.4	-1.3	-1.5	-1.1	-1.7	-1.3	-0.8	-1.7	-1.1
Worry too long after embarrassment	1.1	1.9	3.0	1.0	0.8	1.5	1.4	1.3	1.7	1.5	1.4	1.3	1.4	1.3	1.2	1.2	1.7	1.7	1.7	1.3	1.6	1.1	1.7	1.4	0.9	1.6	1.2
Medication: Ibuprofen	1.1	1.3	5.6	-0.3	-0.6	-1.1	-0.2	-0.6	-1.5	-0.5	-0.3	-0.2	-0.5	-0.8	-0.5	-0.9	-1.6	-2.2	-1.8	-2.4	-1.3	-0.5	-1.3	-0.8	0.0	-2.2	-0.5
Ever had bowel cancer screening	1.1	1.3	5.6	0.7	1.0	0.9	0.4	0.7	1.5	0.6	1.0	0.7	0.8	0.8	0.5	0.6	2.4	2.0	1.6	1.8	1.2	0.3	1.4	0.9	0.7	1.7	0.6
Smoking status: Current	1.1	1.7	5.8	1.1	1.3	0.6	1.0	1.4	1.1	1.3	1.6	1.8	1.3	1.4	1.2	1.9	2.4	0.6	1.3	-0.1	1.2	1.7	1.3	1.4	1.2	0.6	1.3
Alcohol drinker status: Never	1.1	1.4	2.7	1.2	1.2	1.6	0.5	1.2	1.5	1.3	1.1	0.8	1.1	1.4	1.2	1.0	0.7	1.2	1.1	0.8	1.3	1.4	1.5	1.3	0.5	1.4	1.1
Heart disease (siblings)	1.1	1.3	3.0	-1.6	-0.4	-1.6	-1.6	-1.4	-1.1	-1.4	-1.0	-0.9	-1.7	-1.4	-1.6	-0.7	-0.0	0.2	-0.2	0.8	-1.1	-1.0	-0.9	-1.2	-1.6	0.1	-1.5
Pack years of smoking	1.1	1.7	4.7	1.0	0.8	0.4	0.2	1.0	0.8	0.8	0.5	1.3	0.9	1.6	1.2	1.1	1.9	2.0	1.9	2.0	1.5	1.3	1.4	1.4	-0.4	2.2	1.1
BMI	1.0	6.0	13.8	-3.7	-2.9	-2.8	-0.3	-3.0	-1.6	-3.3	-2.2	-2.8	-2.5	-2.9	-3.2	-3.0	-1.1	0.3	-1.7	1.7	-2.2	-2.9	-1.7	-2.7	-2.9	0.4	-3.1
Medication: Co-codamol	1.0	1.2	2.7	1.6	1.2	0.4	-0.9	1.2	1.0	1.4	1.2	1.3	1.4	1.1	1.1	0.6	1.3	0.9	1.1	0.4	1.2	1.1	1.2	1.4	0.8	0.8	1.3
Current tobacco smoking	1.0	1.6	6.1	1.0	1.0	0.6	1.0	1.4	1.2	1.2	1.5	1.9	1.3	1.3	1.2	1.7	2.5	0.6	1.2	-0.1	1.2	1.5	1.3	1.3	1.2	0.5	1.3
Chronic bronchitis/emphysema (father)	1.0	1.2	3.5	-1.2	-0.8	-0.8	-0.8	-1.4	-0.8	-1.7	-1.5	-1.1	-1.1	-0.9	-1.2	-1.6	-0.8	0.4	-0.6	1.3	-0.8	-0.9	-0.7	-1.1	-1.9	0.7	-1.3
Allergy	1.0	2.2	4.5	-0.8	-1.8	-1.1	-1.2	-1.4	-2.1	-1.5	-2.0	-1.3	-1.8	-1.4	-1.2	-0.9	-2.1	-1.7	-1.4	-0.9	-1.6	-1.3	-2.0	-1.5	-1.2	-1.6	-1.3
Hair/balding pattern: Pattern 3	1.0	1.4	2.8	1.3	1.0	0.8	1.7	1.4	0.6	1.6	1.0	1.2	1.0	1.5	1.5	1.4	1.6	0.7	1.2	0.3	1.4	1.4	1.0	1.4	0.6	0.8	1.5
Forced expiratory volume in 1-second (FEV1)	1.0	3.4	9.0	-1.1	-1.6	-1.4	0.4	-1.5	-2.3	-1.5	-1.8	-1.6	-1.8	-1.7	-1.3	-0.9	-2.3	-3.0	-2.7	-2.5	-2.2	-1.3	-2.5	-1.9	-0.9	-2.8	-1.5
Loud music exposure frequency	1.0	1.0	2.1	-1.4	-0.5	-1.5	-1.4	-1.3	-1.0	-1.4	-1.0	-0.9	-1.0	-1.1	-1.3	-1.1	-0.6	-0.0	-0.7	0.5	-1.0	-1.0	-0.8	-1.1	-1.3	-0.0	-1.3
Chest pain or discomfort	1.0	1.5	9.8	-0.7	-0.6	0.3	0.2	-0.5	1.5	-0.1	-0.0	0.0	0.5	0.0	-0.4	-1.4	1.8	2.7	1.3	3.1	0.7	-0.3	1.2	-0.0	-0.6	2.7	-0.5
Basal cell carcinoma (self-reported)	1.0	1.1	3.3	-0.6	-1.8	0.2	0.9	-0.7	-0.7	-1.0	-0.8	-0.9	-0.6	-1.1	-0.8	-0.6	-1.0	-1.7	-1.7	-1.5	-1.2	-1.0	-1.2	-1.2	0.1	-1.6	-0.9
Eye problems/disorders: Diabetes related eye disease	0.9	0.9	2.3	0.6	-0.9	1.0	1.2	0.9	1.2	0.2	0.6	0.9	0.8	0.8	1.0	0.5	0.7	1.5	1.2	1.4	1.3	-0.5	1.0	0.9	1.2	1.2	0.9
Medication for hormone replacement therapy	0.9	1.0	4.2	1.1	0.9	-0.3	0.7	1.1	0.6	1.0	1.0	0.9	0.0	0.9	0.9	2.0	2.0	0.7	1.0	0.3	0.9	1.1	0.9	1.1	0.4	0.6	1.0
Vitamin and mineral supplements	0.9	1.2	6.2	-0.2	1.4	0.2	-0.1	0.2	0.9	0.2	0.2	0.2	0.5	0.8	0.2	-0.3	1.0	2.3	1.5	2.5	1.0	1.1	1.3	0.7	-1.1	2.5	0.2
Noisy workplace	0.9	1.2	4.4	1.1	-0.2	0.9	2.1	1.1	1.1	0.7	1.4	1.3	1.1	1.0	1.1	0.8	1.9	0.6	1.1	-0.0	0.9	0.5	1.0	1.0	1.6	0.2	1.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.9	3.0	6.6	-1.1	-1.4	-1.5	0.2	-1.6	-2.2	-1.4	-1.9	-1.8	-1.9	-1.6	-1.4	-1.0	-1.9	-2.6	-2.1	-1.9	-2.1	-1.4	-2.4	-1.9	-0.9	-2.5	-1.5
Qualifications: NVQ or HND or HNC or equivalent	0.9	1.0	6.4	0.1	-0.1	-0.0	0.4	0.1	1.2	0.4	0.3	-0.0	0.6	0.6	0.2	-0.8	0.6	2.3	1.6	2.5	1.0	0.2	1.2	0.6	-0.2	2.2	0.2
Bipolar Disorder (2018)	0.8	1.2	6.2	0.1	-0.6	-1.2	0.6	-0.3	-1.5	-0.7	-0.5	0.4	-0.6	-0.5	-0.0	-0.6	-1.0	-2.4	-1.3	-2.5	-0.9	-0.5	-1.4	-0.5	0.6	-2.5	-0.0
Bipolar Disorder or Schizophrenia	0.8	1.9	5.3	-1.0	-2.0	-2.3	0.3	-1.1	-1.9	-1.3	-1.7	-0.5	-1.8	-1.4	-1.1	-0.6	-0.1	-1.8	-1.5	-1.2	-1.3	-1.3	-1.8	-1.4	-0.5	-1.8	-1.1
Type 2 Diabetes (T2D) (2018)	0.8	1.6	3.6	-1.8	-1.6	-1.9	1.0	-1.5	-1.4	-1.6	-1.1	-1.0	-1.8	-1.4	-1.4	-1.2	-0.1	-0.0	-0.3	0.7	-1.2	-1.7	-1.3	-1.3	-1.2	-0.3	-1.4
Ever had hysterectomy (womb removed)	0.8	0.9	5.5	-0.5	-2.3	-1.5	0.7	-0.8	-0.4	-1.3	-0.9	-0.1	-1.0	-0.6	-0.5	-1.4	0.3	0.6	0.4	1.3	-0.2	-1.7	-0.6	-0.6	-0.2	0.3	-0.6
Angina	0.8	1.0	2.2	-1.3	-1.5	-1.2	-0.1	-1.4	-0.2	-1.4	-0.5	-0.7	-1.0	-1.3	-1.5	-1.3	0.5	0.7	-0.3	1.2	-0.9	-1.2	-0.4	-1.1	-1.1	0.6	-1.4
Impedance of leg (right)	0.8	4.0	6.7	2.2	1.1	1.8	0.8	2.4	1.7	2.0	1.7	2.5	1.5	2.5	2.6	2.3	2.5	1.6	2.6	0.9	2.4	2.0	2.0	2.5	1.8	1.4	2.5
Arm fat percentage (right)	0.8	3.2	7.6	-2.6	-2.7	-1.4	0.3	-2.1	-0.7	-2.5	-1.6	-1.9	-1.8	-2.1	-2.2	-2.4	-0.2	0.7	-1.1	1.8	-1.3	-2.6	-1.1	-1.9	-1.8	0.7	-2.2
Number of live births	0.8	1.1	2.0	1.3	0.8	1.1	0.6	1.2	1.2	1.0	1.2	1.1	1.4	1.4	1.3	0.5	0.3	0.9	1.0	0.4	1.3	1.4	1.3	1.3	0.8	1.0	1.3
Comparative body size at age 10	0.8	2.3	7.2	-1.5	-1.0	0.3	-1.9	-1.4	-0.2	-1.4	-1.2	-2.1	-0.4	-1.8	-1.6	-2.5	-2.3	-1.2	-2.7	-0.7	-1.5	-1.8	-1.1	-1.7	-0.8	-0.8	-1.6
Number of full brothers	0.8	1.0	5.7	0.7	2.4	-0.1	-0.5	0.6	0.6	1.1	0.8	1.0	1.2	1.2	0.7	0.9	1.3	0.7	1.0	0.3	0.7	2.1	1.0	0.9	-0.5	1.0	0.6
Overall health rating	0.8	1.7	5.3	-1.6	-0.8	-2.3	-1.8	-1.5	-1.2	-1.4	-1.1	-1.2	-1.7	-1.5	-1.8	-0.8	0.3	0.3	-0.6	1.0	-1.2	-0.9	-0.9	-1.2	-2.1	0.3	-1.6
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.7	3.8	0.9	0.6	1.3	1.0	1.3	1.9	1.6	1.6	1.5	1.6	1.4	1.2	0.7	1.0	1.6	1.4	1.0	1.5	1.0	1.7	1.3	1.2	1.4	1.1
Friendships satisfaction	0.8	1.0	3.9	0.8	2.0	0.6	0.1	0.8	1.2	1.5	1.2	0.7	1.7	0.8	0.5	0.2	0.3	0.9	0.6	0.3	0.9	1.5	1.4	0.9	0.2	1.1	0.7
Supplements: Fish oil (including cod liver oil)	0.8	1.0	8.2	-0.0	0.0	-0.3	0.8	0.0	-1.0	-0.1	0.3	0.0	-0.1	-0.4	-0.1	0.7	-0.2	-2.4	-1.3	-2.9	-1.0	0.2	-1.0	-0.4	0.7	-2.4	-0.1
Schizophrenia (2018)	0.7	1.5	4.3	-1.4	-2.1	-2.0	-0.0	-1.2	-1.3	-1.0	-1.8	-1.0	-1.8	-1.3	-1.4	-0.3	0.6	-0.4	-0.9	0.5	-1.0	-1.3	-1.2	-1.4	-1.2	-0.3	-1.3
Crohns Disease (2017)	0.7	1.6	4.8	-0.0	1.4	-0.2	1.0	0.7	1.0	1.0	1.1	1.2	0.8	1.2	0.7	0.6	2.1	2.2	2.0	2.0	1.2	1.3	1.6	1.2	-0.4	2.2	0.7
Waist Hip Ratio (WHR)	0.7	3.0	13.0	1.3	0.9	1.4	2.1	1.7	2.0	1.6	1.8	2.2	1.5	1.8	1.6	1.8	3.6	1.6	1.6	1.0	1.9	1.2	1.8	1.7	1.5	1.6	1.6
Hair Pigment	0.7	21.4	47.3	-3.9	-3.3	-3.1	-2.7	-4.4	-5.6	-4.7	-4.5	-4.8	-4.5	-4.9	-4.3	-3.2	-6.9	-5.9	-5.3	-4.3	-5.5	-4.5	-5.9	-5.0	-2.4	-6.0	-4.4
Relative age of first facial hair	0.7	1.4	3.0	1.6	1.1	1.1	1.4	1.3	0.4	1.3	1.4	1.4	1.3	1.1	1.3	1.2	-0.8	-0.8	0.4	-1.7	0.6	1.3	0.5	1.0	1.7	-1.0	1.3
Body mass index (BMI)	0.7	3.0	5.8	-2.3	-2.4	-1.7	0.1	-2.1	-1.1	-2.3	-1.4	-1.9	-1.5	-2.2	-2.2	-2.4	-1.2	-0.5	-1.8	0.3	-1.8	-2.3	-1.4	-2.1	-1.5	-0.5	-2.2
Impedance of leg (left)	0.7	3.3	8.0	1.8	1.1	1.0	0.4	1.9	1.3	1.6	1.1	2.2	1.0	2.3	2.2	1.9	2.7	2.0	2.8	1.7	2.3	1.8	1.8	2.2	1.0	1.8	2.1
Neuroticism score	0.7	1.4	6.4	1.1	2.5	0.9	0.3	1.2	0.8	1.5	1.6	1.5	1.4	1.3	1.1	1.2	0.9	0.5	1.2	-0.3	1.0	1.8	1.2	1.3	0.7	0.4	1.2
Medication: Cholesterol lowering	0.7	1.1	3.2	-1.6	-1.2	-1.8	0.6	-1.2	-1.0	-1.5	-0.7	-0.8	-1.7	-1.3	-1.4	-0.5	0.3	-0.1	-0.8	0.3	-1.1	-1.2	-0.8	-1.0	-1.2	-0.2	-1.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.0	3.6	-1.0	-0.1	-1.3	-1.9	-1.1	-0.9	-1.5	-1.0	-1.1	-1.5	-0.9	-1.2	0.2	0.6	-0.1	-0.4	0.5	-1.0	-0.5	-0.7	-1.0	-1.6	0.1	-1.3
Mouth/teeth dental problems: Bleeding gums	0.7	1.0	4.1	-0.5	0.6	0.1	0.4	0.4	0.9	0.4	0.5	0.8	0.0	0.7	0.4	0.5	1.8	1.9	1.3	2.0	1.1	0.4	1.1	0.7	-0.2	2.0	0.4
Glaucoma (self-reported)	0.7	0.9	2.2	-0.6	0.5	-1.2	-0.5	-0.8	-1.3	-0.6	-0.5	-0.8	-0.7	-0.9	-1.0	-0.6	-0.8	-1.5	-1.3	-1.5	-1.3	-0.1	-1.0	-0.9	-0.8	-1.4	-0.8
Forced vital capacity (FVC), Best measure	0.7	2.5	5.7	-1.1	-0.9	-1.8	-0.3	-1.5	-2.1	-1.1	-1.7	-1.5	-1.6	-1.4	-1.3	-1.1	-1.8	-2.4	-1.9	-1.9	-2.0	-1.0	-2.1	-1.7	-1.0	-2.3	-1.5
Arm fat percentage (left)	0.7	2.7	7.1	-2.4	-2.7	-1.4	0.5	-1.9	-0.7	-2.3	-1.5	-1.7	-1.6	-1.9	-2.0	-2.3	-0.3	0.6	-1.0	1.6	-1.2	-2.4	-1.0	-1.7	-1.6	0.6	-2.0
Commuting to job workplace: Walk	0.7	0.7	3.6	-0.8	-1.1	-0.9	-0.2	-0.8	-0.9	-1.1	-1.1	-0.9	-1.9	-0.7	-0.8	0.3	-0.0	0.3	-0.2	0.9	-0.6	-1.1	-0.7	-0.7	-1.1	0.3	-0.8
Number of self-reported non-cancer illnesses	0.7	1.2	2.8	-1.2	-0.9	-1.7	0.1	-1.4	-0.8	-1.1	-1.0	-0.9	-1.4	-1.4	-1.6	-1.0	0.4	0.2	-0.6	0.7	-1.2	-0.9	-0.7	-1.2	-1.7	0.2	-1.5
Medication: Bendroflumethiazide	0.7	1.0	2.9	-0.6	-1.6	-0.6	-0.8	-0.9	-0.5	-0.9	-0.7	-0.8	-0.5	-1.4	-1.0	-1.7	-1.2	-0.9	-1.5	-0.6	-1.0	-1.6	-0.9	-1.1	-0.1	-0.9	-1.0
Heart attack/myocardial infarction (self-reported)	0.7	0.8	1.7	-1.2	-1.3	-1.2	0.3	-0.9	-0.8	-1.3	-0.6	-1.0	-1.2	-1.2	-1.2	0.1	0.1	-0.4	-0.9	-0.1	-1.1	-1.2	-0.8	-1.1	-0.7	-0.6	-1.1
Impedance of whole body	0.7	3.8	8.2	1.8	1.4	1.6	0.9	2.0	1.6	1.8	1.3	2.1	1.2	2.3	2.2	2.0	2.6	2.3	2.9	1.9	2.5	1.8	2.0	2.3	1.1	2.2	2.2
Intelligence (Savage-Jansen 2018)	0.6	2.0	5.3	-2.3	-0.4	-1.1	0.2	-1.7	-1.6	-1.4	-1.6	-2.0	-2.1	-1.5	-1.6	-1.1	-1.2	-0.7	-1.4	0.0	-1.5	-1.2	-1.5	-1.6	-1.8	-0.6	-1.7
Coronary Artery Disease (CAD)	0.6	0.7	3.1	-1.8	0.3	-0.1	-0.2	-1.0	0.1	-0.7	-0.3	-0.9	-0.2	-1.0	-1.4	-1.0	0.4	0.6	-0.4	1.0	-0.6	-0.3	-0.0	-1.1	-1.4	0.8	-1.4
Number of treatments/medications taken	0.6	1.0	3.8	-0.7	-2.0	-1.5	0.2	-0.9	-0.9	-1.3	-0.6	-0.3	-1.5	-1.3	-1.0	-0.6	0.1	-0.8	-1.0	-0.5	-1.0	-1.5	-1.1	-1.0	-0.2	-1.0	-0.9
Townsend deprivation index at recruitment	0.6	0.8	2.7	-1.5	-0.1	-1.2	-1.2	-1.0	-0.7	-1.3	-0.6	-0.8	-0.9	-0.8	-1.1	-0.5	0.5	0.5	0.0	1.0	-0.8	-0.3	-0.4	-0.7	-1.6	0.5	-1.1
Stomach or abdominal pain in last month	0.6	0.7	1.6	-0.7	-1.0	-0.9	-0.2	-0.7	-0.7	-0.7	-0.8	-0.6	-0.9	-1.0	-0.9	0.1	0.3	-1.2	-1.2	-0.9	-1.1	-0.8	-1.0	-1.1	-0.3	-1.1	-0.9
Number of incorrect matches in round	0.6	0.9	3.1	-0.2	-0.2	-1.7	0.1	-0.8	-1.7	-0.5	-0.3	-0.1	-1.0	-1.0	-0.9	-0.4	-0.8	-1.5	-0.5	-1.4	-1.3	-0.3	-1.3	-0.8	-0.5	-1.7	-0.8
Past tobacco smoking	0.6	1.1	3.8	-0.9	-1.4	-0.7	-0.7	-1.0	-0.9	-1.2	-1.4	-1.6	-1.9	-1.2	-1.0	-0.5	-0.9	-0.2	-0.7	0.5	-0.8	-1.8	-1.1	-1.1	-0.6	-0.3	-1.0
Forced vital capacity (FVC)	0.6	2.4	7.3	-0.8	-0.9	-1.6	0.3	-1.2	-2.1	-0.9	-1.4	-1.1	-1.4	-1.2	-1.0	-0.9	-1.9	-2.7	-2.2	-2.4	-1.9	-0.7	-2.1	-1.5	-0.8	-2.5	-1.1
Diabetes (self-reported)	0.6	0.9	2.1	-1.0	-1.5	-1.4	1.3	-1.1	-1.0	-1.1	-1.0	-0.8	-1.3	-1.0	-1.0	-0.4	0.3	-0.0	-0.3	0.6	-0.9	-1.2	-0.9	-1.0	-1.1	-0.1	-1.1
Time employed in main current job	0.6	0.7	2.6	0.9	-0.5	0.7	1.6	0.7	0.9	0.6	0.6	0.6	0.7	0.8	0.8	0.4	0.8	1.1	1.3	1.0	1.0	0.2	0.8	0.7	0.9	0.9	0.7
Medication: Lansoprazole	0.6	0.7	2.0	0.2	1.2	-0.1	0.9	0.4	0.6	0.6	0.8	0.7	0.7	0.7	0.4	-0.1	1.1	1.4	1.4	1.2	0.8	0.8	1.0	0.8	0.1	1.2	0.5
Pulse wave peak to peak time	0.6	0.7	2.8	-1.0	-0.6	-1.2	-1.7	-0.9	-0.8	-1.0	-1.2	-0.6	-1.1	-0.8	-0.9	-0.4	-0.7	0.2	-0.1	0.9	-0.5	-0.7	-0.7	-0.6	-1.3	0.2	-0.7
Migraine (self-reported)	0.6	0.7	4.2	0.4	2.1	0.7	-0.6	0.6	1.1	0.9	0.9	0.4	0.9	0.7	0.4	0.2	1.1	0.8	0.5	0.4	0.7	1.3	1.2	0.7	-0.0	1.1	0.5
Medication: Seretide 50 evohaler	0.6	0.7	3.2	-0.9	-0.5	-0.3	-1.2	-0.7	-0.1	-1.0	-1.1	-1.2	-0.8	-0.5	-0.6	-0.9	-0.0	1.0	0.2	1.8	0.0	-0.9	-0.1	-0.4	-1.0	1.2	-0.6
Medication: Aspirin	0.6	0.8	2.1	-1.0	-1.1	-1.4	-0.3	-0.9	-1.0	-1.2	-0.4	-0.6	-1.1	-1.2	-1.0	-0.3	-0.1	-0.7	-0.7	-0.4	-1.1	-1.3	-1.0	-1.0	-0.2	-1.0	-1.0
Prostate Cancer	0.5	0.7	2.6	0.1	0.9	-0.9	-1.0	-0.1	-1.3	-0.5	-0.7	-0.3	-0.7	-0.1	0.2	-0.2	-1.1	-1.6	-0.7	-1.5	-0.7	-0.0	-1.2	-0.2	-0.2	-1.6	0.1
Body Mass Index (BMI) (2010)	0.5	0.7	1.9	-0.9	-1.2	-0.2	0.1	-0.9	-0.3	-0.5	-0.5	-0.8	-0.3	-1.2	-1.1	-1.3	-1.1	-0.9	-1.4	-0.8	-1.1	-0.7	-0.6	-1.0	-0.4	-0.7	-1.1
HbA1C	0.5	0.5	3.6	0.7	-0.2	0.3	1.9	0.6	0.5	0.8	0.7	1.0	0.4	0.7	0.7	0.6	1.0	0.7	0.7	0.4	0.8	0.5	0.8	0.7	0.5	0.6	0.6
LDL Cholesterol	0.5	0.8	2.4	1.2	-0.4	0.7	1.5	1.0	0.4	0.7	1.1	1.4	0.8	1.0	1.3	0.8	-0.4	-0.1	0.5	-0.7	0.7	0.8	0.6	1.1	1.2	-0.2	1.2
Type 2 Diabetes (T2D) (2012)	0.5	0.6	1.1	-0.7	-0.9	-0.8	0.6	-0.9	-1.0	-0.9	-0.7	-1.0	-0.7	-0.9	-0.9	-0.7	-0.7	-0.5	-0.4	-0.1	-0.9	-0.9	-1.0	-1.0	-0.5	-0.7	-1.0
Frequency of depressed mood in last 2 weeks	0.5	0.7	2.5	0.7	0.6	0.6	0.5	1.0	0.9	0.9	1.5	1.2	0.9	0.6	0.8	0.8	0.8	0.1	0.7	-0.6	0.7	0.6	0.8	0.8	1.6	-0.2	0.8
Other serious medical condition/disability diagnosed by doctor	0.5	0.6	2.3	-1.0	-0.4	-0.4	-0.6	-0.7	-0.3	-0.4	-0.5	-0.6	-0.2	-1.1	-1.0	-0.4	0.1	-1.1	-1.5	-1.0	-1.0	-0.7	-0.7	-1.0	-0.2	-1.0	-0.9
Relative age voice broke	0.5	0.8	3.8	0.0	-0.6	-0.3	0.9	-0.3	-1.2	-0.4	-0.1	0.2	-0.6	-0.3	0.0	-0.2	-1.9	-1.7	-0.5	-1.8	-0.8	-0.3	-1.1	-0.4	0.6	-2.0	-0.1
Illnesses of siblings	0.5	0.8	2.8	0.6	1.7	1.1	0.7	0.8	0.5	0.9	0.7	0.2	0.8	1.2	0.9	0.9	-0.3	0.8	0.9	0.5	0.8	1.5	1.0	1.0	-0.2	0.9	0.8
Father’s age at death	0.5	0.6	2.6	1.2	-0.4	1.6	0.4	1.0	0.8	0.5	0.2	0.6	0.8	0.9	1.1	0.4	-0.7	0.4	0.9	0.3	1.0	0.3	0.5	0.8	1.2	0.3	1.1
Headache pain in last month	0.5	0.9	1.6	-1.0	-0.4	-1.3	-0.9	-1.0	-0.8	-0.9	-0.7	-0.8	-0.8	-1.2	-1.2	-0.7	-0.1	-1.0	-1.1	-0.8	-1.2	-1.0	-1.0	-1.2	-0.3	-1.1	-1.2
Birth weight	0.5	1.1	6.3	0.0	-0.8	0.3	1.3	-0.0	-0.6	-0.1	-0.2	-0.2	-0.0	-0.5	-0.0	0.1	-1.1	-2.3	-1.9	-2.5	-0.9	-0.5	-1.1	-0.7	0.8	-2.2	-0.2
Angina (self-reported)	0.5	0.6	1.4	-0.9	-1.2	-0.8	0.1	-1.0	0.1	-1.0	-0.2	-0.3	-0.6	-0.9	-1.1	-1.1	0.7	0.8	-0.1	1.1	-0.5	-0.9	-0.1	-0.7	-0.7	0.7	-1.1
Smoking status: Previous	0.5	0.7	2.9	0.9	0.6	0.9	0.6	0.9	1.0	1.1	1.1	1.3	1.7	1.0	0.9	0.0	0.3	0.3	0.5	-0.3	0.8	1.0	0.9	0.9	0.8	0.3	0.9
Handedness (chirality/laterality): Left-handed	0.5	0.6	1.7	1.1	0.8	0.6	0.8	0.9	0.2	0.7	0.8	0.4	0.8	0.8	0.9	1.3	0.6	-0.6	0.2	-1.1	0.3	1.0	0.2	0.7	0.8	-0.7	0.8
Long-standing illness, disability or infirmity	0.5	0.7	2.4	-1.0	-1.6	-1.4	0.3	-0.9	-0.5	-0.9	-0.6	-0.4	-1.2	-1.1	-1.2	-0.2	1.1	0.1	-0.4	0.5	-0.7	-1.0	-0.6	-0.9	-0.8	0.0	-1.1
Miserableness	0.5	0.9	5.6	-0.1	1.6	0.3	1.8	0.7	0.8	1.0	1.5	0.7	0.8	0.6	0.4	1.0	2.4	0.5	0.4	-0.1	0.6	1.1	1.1	0.7	0.4	0.6	0.5
Guilty feelings	0.5	0.8	3.2	-1.0	1.7	-1.2	-1.3	-1.0	-1.1	-0.4	-0.6	-0.7	-0.5	-0.7	-1.0	-0.4	-0.6	-0.6	-0.6	-0.4	-1.1	0.5	-0.7	-0.7	-1.8	-0.4	-1.0
Pain type(s) experienced in last month: Hip pain	0.5	0.6	2.2	0.4	0.8	0.3	-0.2	0.3	1.2	0.7	0.9	0.7	1.0	0.5	0.1	-0.0	0.3	1.4	0.8	1.1	0.6	0.9	1.2	0.6	-0.3	1.5	0.1
Ever smoked	0.5	0.8	2.6	0.8	1.3	0.5	-0.0	0.9	0.6	1.0	1.0	1.3	1.5	1.1	0.9	0.9	0.9	0.2	0.6	-0.3	0.8	1.6	0.9	1.0	0.3	0.4	0.9
Irritability	0.5	0.9	8.2	0.7	2.9	-0.1	-0.9	0.7	-0.0	1.0	1.3	1.4	1.2	0.7	0.5	0.8	-0.2	-0.2	0.6	-0.9	0.3	1.6	0.6	0.8	0.2	-0.3	0.7
Risk taking	0.5	0.7	4.2	-1.1	-2.0	-0.5	-0.1	-0.7	-0.2	-1.1	-1.0	-0.8	-0.8	-1.0	-0.8	-0.1	-0.4	-0.6	-1.4	-0.1	-0.7	-1.4	-0.8	-1.0	-0.2	-0.3	-0.9
Neuroticism (Nagel 2018)	0.4	1.0	4.1	0.9	2.0	0.9	1.0	0.9	0.9	1.3	1.6	1.2	1.6	0.9	0.8	0.0	0.4	0.4	0.9	-0.3	0.8	1.3	1.0	0.9	0.9	0.3	0.9
Worry (Nagel 2018)	0.4	0.8	4.5	-0.4	0.3	0.2	-0.3	-0.7	-0.8	-0.4	-0.2	-0.7	-0.0	-0.8	-0.6	-1.4	-2.1	-1.4	-0.9	-1.4	-0.9	-0.5	-0.9	-0.9	0.2	-1.5	-0.6
Rheumatoid Arthritis	0.4	0.6	2.2	0.5	-0.2	0.1	0.6	0.5	0.7	0.5	0.3	0.7	0.2	0.8	0.7	-0.0	0.6	1.4	1.3	1.5	1.1	0.2	0.8	0.9	0.3	1.4	0.7
Ulcerative Colitis	0.4	0.6	2.7	0.1	-0.1	-0.1	1.3	0.4	0.5	0.7	0.4	1.2	0.4	0.7	0.5	0.4	1.6	1.0	1.4	1.0	0.8	0.4	0.7	0.6	0.4	0.8	0.5
Neuroticism	0.4	0.9	2.4	1.0	1.4	0.8	0.9	0.9	0.7	1.1	1.6	1.4	1.3	0.9	0.9	-0.0	-0.0	0.1	1.0	-0.6	0.8	1.0	0.8	1.0	1.3	-0.2	1.0
Chronotype (morning person)	0.4	0.8	4.4	-0.0	0.1	0.3	0.5	-0.2	-0.8	-0.3	0.3	-0.5	-0.5	-0.6	-0.2	-0.4	-1.8	-1.7	-1.0	-2.1	-0.8	-0.5	-0.9	-0.5	1.0	-2.0	-0.2
Tanning	0.4	4.4	18.3	0.6	0.8	-0.8	1.8	0.9	1.9	1.4	1.4	2.3	1.3	1.7	1.1	-0.2	4.3	3.7	3.3	3.6	2.2	1.3	2.4	1.8	0.1	3.5	1.2
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.7	2.1	0.8	1.3	0.3	0.2	0.7	0.9	0.9	1.2	1.2	1.1	0.7	0.6	0.8	1.5	0.3	0.6	-0.3	0.6	1.0	0.9	0.6	0.9	0.2	0.6
Financial difficulties in last 2 years	0.4	0.5	4.5	-0.3	0.9	-0.4	-1.0	0.1	0.4	0.3	0.3	0.2	0.1	0.2	-0.1	0.8	2.1	1.1	0.8	1.1	0.4	0.7	0.6	0.3	-0.5	1.2	-0.0
Heart attack	0.4	0.5	1.3	-0.9	-1.1	-1.0	0.3	-0.6	-0.5	-1.1	-0.5	-0.8	-1.1	-0.9	-0.9	0.5	0.4	-0.1	-0.5	0.2	-0.8	-0.9	-0.5	-0.8	-0.6	-0.3	-0.9
Worrier / anxious feelings	0.4	0.8	4.1	0.1	-0.6	0.4	-0.2	-0.3	-0.7	-0.1	-0.4	-0.0	-0.1	-0.6	-0.2	-1.0	-2.0	-1.7	-1.2	-1.8	-0.7	-0.5	-1.0	-0.6	0.6	-1.8	-0.2
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	5.9	0.2	0.9	-0.1	0.3	0.7	0.4	0.5	1.1	0.8	0.2	0.4	0.3	1.9	2.4	0.4	0.5	-0.1	0.3	0.8	0.7	0.6	0.2	0.3	0.4
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	2.6	-0.3	-1.6	-0.6	0.4	-0.4	-0.7	-0.7	-0.9	-0.4	-0.5	-0.4	-0.2	-0.7	-0.4	-0.8	-0.6	-0.4	-0.5	-1.0	-0.9	-0.7	0.2	-0.8	-0.3
Pulse wave reflection index	0.4	0.4	3.2	0.6	-0.4	-0.1	1.8	0.2	-0.4	0.2	0.3	-0.0	0.3	0.0	0.3	-0.5	-0.3	-1.2	-0.7	-1.6	-0.2	0.1	-0.3	0.1	0.7	-1.2	0.3
Number of children fathered	0.4	0.5	3.1	0.0	-0.5	0.3	0.8	-0.0	0.7	-0.1	0.2	0.4	-0.0	0.3	0.2	-0.9	-0.1	1.6	1.2	1.8	0.6	-0.3	0.7	0.3	0.1	1.3	0.1
Alcohol intake frequency.	0.4	0.9	2.3	-0.8	-1.3	-0.7	-1.3	-0.9	-0.5	-1.2	-1.0	-1.3	-1.1	-1.2	-1.1	-0.8	0.2	-0.4	-0.8	0.1	-0.9	-1.5	-0.9	-1.1	-0.3	-0.5	-1.1
Comparative height size at age 10	0.4	2.0	5.1	1.7	0.1	1.6	1.4	1.7	2.3	1.9	1.8	1.5	2.2	1.3	1.6	0.1	-0.0	0.6	0.3	-0.3	1.6	0.7	1.7	1.5	2.2	0.6	1.7
Leg pain on walking	0.4	0.5	1.3	-0.7	-0.8	-0.5	-0.4	-0.7	-0.5	-0.7	-0.1	-0.2	-0.3	-1.0	-0.8	-1.1	-0.5	-0.6	-1.1	-0.6	-0.8	-1.0	-0.6	-0.8	-0.1	-0.7	-0.8
Medication: Aspirin	0.4	0.6	1.3	-0.9	-1.1	-1.1	0.0	-0.8	-0.7	-1.0	-0.1	-0.5	-1.0	-1.2	-1.0	-0.0	0.2	-0.3	-0.4	-0.2	-0.9	-1.1	-0.7	-0.8	-0.1	-0.7	-0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	1.2	-1.0	-0.8	-0.6	-0.2	-1.0	-0.5	-0.8	-0.7	-0.4	-0.6	-0.9	-0.9	-1.1	-0.6	-0.1	-0.5	0.3	-0.7	-0.7	-0.6	-0.9	-0.7	-0.1	-1.0
Mood swings	0.4	0.7	4.8	0.7	1.0	0.2	0.7	0.9	0.4	0.6	0.9	1.0	0.7	0.8	0.7	1.5	2.2	0.1	0.5	-0.3	0.6	0.8	0.6	0.7	0.7	0.1	0.8
Diabetes diagnosed by doctor	0.4	0.7	1.8	-1.0	-1.3	-1.3	0.8	-0.9	-0.7	-1.0	-0.8	-0.6	-1.3	-0.9	-0.9	-0.2	0.7	0.4	-0.0	1.0	-0.6	-1.2	-0.6	-0.8	-0.9	0.2	-0.9
Medication for cholesterol	0.4	0.6	2.6	0.1	0.2	1.6	1.1	0.7	1.1	0.9	0.4	0.7	1.0	0.9	0.8	0.2	0.5	0.7	0.5	0.5	1.0	0.5	0.8	0.7	0.7	0.8	0.8
Mineral and other dietary supplements	0.4	0.6	2.5	-0.6	-0.6	-0.5	-0.9	-0.8	-0.2	-0.7	-1.1	-0.9	-1.1	-0.6	-0.8	-0.9	-0.1	0.9	0.1	1.6	-0.2	-0.8	-0.2	-0.6	-1.1	0.9	-0.8
Financial situation satisfaction	0.4	0.5	1.4	-0.7	0.5	-0.8	-0.5	-0.6	-0.9	-0.7	0.2	-0.1	-0.2	-0.6	-0.6	-0.7	-0.9	-1.0	-0.5	-1.2	-0.9	0.4	-0.6	-0.5	-0.5	-1.0	-0.6
Medication: Atorvastatin	0.4	0.6	1.9	-1.4	-1.2	-0.6	-1.0	-0.8	-0.1	-1.3	-0.3	-0.5	-0.7	-1.0	-1.0	-0.5	0.2	0.3	-0.2	0.5	-0.6	-1.0	-0.3	-0.8	-0.3	0.1	-1.0
Number of operations (self-reported)	0.4	0.6	1.9	0.8	-0.5	0.4	1.4	0.8	0.7	0.2	0.6	1.1	0.4	0.9	0.9	0.8	0.8	0.7	1.0	0.5	0.9	0.2	0.6	0.7	0.9	0.5	0.8
Unable to work because of sickness or disability	0.4	0.5	2.7	0.5	-0.3	-0.0	-0.1	0.6	0.1	0.2	0.6	1.0	0.1	0.0	0.4	1.2	1.3	-1.2	-0.7	-1.6	-0.1	-0.2	-0.2	0.1	1.4	-1.3	0.4
Supplements: Calcium	0.4	0.5	1.9	0.6	-1.0	0.6	0.8	0.7	0.8	0.1	0.7	0.8	0.5	0.5	0.7	0.5	1.0	0.5	0.9	0.3	0.7	-0.3	0.5	0.6	1.4	0.1	0.7
Alzheimer’s Disease (in father)	0.3	0.4	1.8	-0.2	-0.6	-1.2	0.8	-0.4	-1.3	-0.3	-0.2	0.0	-0.6	-0.3	-0.0	-0.5	-0.2	-0.8	-0.2	-0.7	-0.6	-0.6	-0.8	-0.3	-0.0	-1.1	-0.1
Irritable Bowel Disease (IBD)	0.3	0.8	3.1	-0.4	-0.1	-0.6	1.3	0.4	0.5	0.4	0.3	1.0	-0.1	0.7	0.4	0.3	1.8	1.6	1.5	1.7	0.8	0.3	0.8	0.6	-0.2	1.5	0.4
Ulcerative Colitis (UC)	0.3	0.5	2.7	-1.0	-1.7	-0.9	1.0	-0.6	-0.4	-0.7	-0.9	-0.2	-1.0	-0.4	-0.5	-0.8	0.3	0.3	0.3	0.9	-0.2	-1.1	-0.5	-0.6	-0.3	0.2	-0.5
Age at First Birth	0.3	0.4	2.6	-0.6	0.5	0.1	-1.6	-0.4	-0.7	-0.3	-0.8	-0.8	-0.4	-0.5	-0.6	-0.2	-0.7	-0.7	-1.1	-0.5	-0.6	-0.0	-0.5	-0.6	-1.0	-0.3	-0.6
Fasting Glucose	0.3	0.4	1.6	-0.7	0.3	0.1	-0.7	-0.6	0.0	-0.5	-0.5	-1.2	-0.3	-0.2	-0.7	-0.2	0.3	0.9	0.3	1.3	-0.2	-0.2	0.2	-0.4	-1.0	1.0	-0.8
Diabetes (father)	0.3	0.4	1.8	0.2	-0.9	-0.2	0.9	-0.1	-0.3	-0.3	-0.3	-0.2	-0.3	-0.5	-0.0	-0.1	-0.5	-1.3	-1.1	-1.3	-0.5	-0.8	-0.7	-0.4	0.6	-1.3	-0.1
Severe depression (siblings)	0.3	0.3	2.3	-0.5	-0.1	0.1	-0.3	-0.3	0.5	-0.2	-0.1	0.2	0.1	-0.1	-0.2	-0.9	0.2	1.2	0.4	1.5	0.3	-0.2	0.5	-0.0	-0.6	1.3	-0.3
Trunk fat percentage	0.3	1.1	5.7	-0.9	-1.6	-0.1	1.9	-0.3	0.9	-0.5	0.1	0.0	-0.1	-0.2	-0.4	-1.0	1.4	2.0	0.7	2.4	0.6	-0.9	0.7	-0.0	-0.4	2.0	-0.3
Age when periods started (menarche)	0.3	0.8	2.4	-0.6	-1.6	-0.9	0.4	-0.8	-1.3	-1.5	-1.1	-0.6	-1.4	-0.6	-0.4	-0.6	-1.1	-0.6	-0.6	-0.0	-0.6	-1.2	-1.1	-0.8	-0.5	-0.6	-0.6
Multivitamins +/- minerals	0.3	0.4	2.1	0.3	-0.8	0.2	0.6	0.3	-0.2	0.4	-0.0	0.3	-0.3	-0.2	0.2	0.9	-0.1	-1.3	-0.7	-1.5	-0.3	-0.5	-0.6	-0.2	1.0	-1.4	0.1
High blood pressure (mother)	0.3	0.4	2.3	-0.7	-0.4	-0.3	-0.4	-0.2	0.7	-0.1	0.0	-0.2	-0.1	-0.1	-0.3	0.1	1.5	1.3	0.6	1.5	0.3	-0.2	0.5	-0.1	-0.3	1.2	-0.3
Trunk fat mass	0.3	1.2	5.1	-0.6	-1.4	0.3	2.2	0.0	1.4	-0.1	0.6	0.3	0.5	0.0	-0.1	-0.9	1.5	2.1	0.6	2.3	0.8	-0.7	1.2	0.2	0.0	2.1	-0.1
Hair/balding pattern: Pattern 2	0.3	0.4	1.5	0.7	1.1	0.5	-1.2	0.4	-0.1	0.3	0.4	0.4	0.5	0.1	0.3	0.5	-0.6	-0.8	0.1	-1.1	-0.1	0.5	-0.1	0.2	0.9	-1.0	0.4
Medication: Ramipril	0.3	0.4	1.1	-1.1	-1.0	-0.4	0.1	-0.7	0.2	-0.7	-0.5	-0.5	-0.5	-0.8	-0.9	-0.4	0.2	0.6	-0.7	0.9	-0.4	-0.8	-0.1	-0.7	-0.8	0.7	-0.9
Fluid intelligence score	0.3	0.7	1.9	-1.2	0.2	-0.4	0.1	-0.9	-0.9	-0.6	-0.8	-1.2	-0.4	-0.7	-0.8	-1.0	-1.4	-0.9	-1.3	-0.6	-1.0	-0.1	-0.7	-0.8	-1.3	-0.5	-0.9
Trunk fat-free mass	0.3	1.4	5.2	0.8	0.1	1.6	2.2	1.0	2.3	1.4	1.8	1.0	2.2	0.8	0.8	-0.2	0.1	0.8	-0.1	-0.1	1.0	0.5	1.6	0.8	1.6	0.8	0.8
Pulse rate	0.3	0.5	1.4	-1.2	0.1	-0.7	-0.8	-1.0	-0.4	-0.7	-0.6	-0.9	-0.5	-0.7	-0.9	-1.1	-0.4	-0.1	-0.4	0.3	-0.7	-0.6	-0.5	-0.9	-0.7	-0.1	-1.0
Prospective memory result	0.3	0.4	1.4	0.7	-0.5	1.2	0.0	0.8	0.9	0.3	0.5	0.2	0.2	0.5	0.6	1.2	0.4	0.6	0.4	0.5	0.8	-0.2	0.6	0.6	0.9	0.6	0.6
Arm fat mass (right)	0.3	1.3	5.1	-1.7	-2.3	-0.6	1.0	-1.2	0.2	-1.5	-0.6	-1.0	-0.5	-1.3	-1.4	-2.0	-0.0	0.7	-0.9	1.2	-0.6	-1.9	-0.3	-1.2	-0.7	0.7	-1.3
Blood clot in the leg (DVT)	0.3	0.3	2.3	0.3	0.7	0.1	0.2	0.5	-0.0	0.4	0.6	0.4	0.2	0.2	0.3	1.5	0.7	-0.9	-0.5	-1.4	-0.1	0.5	0.0	0.2	0.5	-0.8	0.3
Medication: Amlodipine	0.3	0.4	1.9	-1.0	0.7	-1.2	0.1	-0.8	-0.4	-0.1	-0.3	-0.6	-0.3	-0.4	-0.9	-0.6	0.9	0.5	0.3	0.8	-0.5	0.2	-0.2	-0.5	-1.4	0.6	-0.8
Shortness of breath walking on level ground	0.3	0.3	1.8	-0.1	0.7	0.4	0.3	-0.1	0.5	-0.1	0.2	0.0	-0.3	0.2	-0.2	0.4	0.7	1.3	0.8	1.4	0.2	0.3	0.6	0.1	-0.6	1.2	-0.3
Neck or shoulder pain in last month	0.3	0.5	1.6	-0.4	-0.6	-1.3	0.8	-0.6	-1.0	-0.7	-0.1	0.0	-0.5	-0.7	-0.5	-0.6	-0.1	-0.9	-0.6	-0.9	-0.7	-0.8	-0.8	-0.6	0.1	-1.1	-0.5
Medication: Omeprazole	0.3	0.4	1.7	0.3	-0.8	0.0	-0.2	-0.2	-0.3	-0.4	0.3	0.5	-0.0	-0.5	-0.2	-0.9	-1.0	-1.0	-0.5	-1.2	-0.5	-0.7	-0.5	-0.5	1.0	-1.3	-0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	2.0	0.0	-0.1	1.4	0.4	0.3	1.2	0.2	0.3	-0.3	0.9	0.4	0.2	-0.2	0.3	1.0	0.5	1.0	0.7	0.2	0.8	0.3	0.3	1.1	0.2
Arm predicted mass (right)	0.3	1.5	5.5	0.8	0.1	1.2	2.3	1.1	2.2	1.4	2.0	1.3	2.2	1.0	0.9	-0.2	0.3	0.9	0.1	-0.1	1.1	0.8	1.7	1.0	1.5	0.9	0.9
Number of full sisters	0.3	0.4	1.3	1.1	0.1	0.5	0.4	0.4	0.4	0.5	0.6	0.9	0.7	0.7	0.6	-0.4	-0.5	0.7	1.1	0.5	0.6	0.4	0.6	0.6	0.5	0.5	0.6
Supplements: Vitamin C	0.3	0.3	0.9	-0.0	-0.9	0.0	-0.4	-0.4	-0.2	-0.9	-0.2	-0.6	-0.1	-0.7	-0.5	-0.5	-0.5	-0.8	-0.7	-0.7	-0.6	-0.9	-0.6	-0.7	0.5	-0.9	-0.5
Arm fat mass (left)	0.3	1.4	5.3	-1.7	-2.3	-0.8	1.2	-1.2	0.2	-1.5	-0.6	-1.0	-0.6	-1.3	-1.4	-1.9	0.1	0.8	-0.8	1.4	-0.6	-1.8	-0.3	-1.2	-0.8	0.8	-1.4
Ever taken oral contraceptive pill	0.3	0.3	2.0	-0.8	-0.5	-1.0	0.5	-0.3	0.2	0.0	-0.2	0.4	-0.1	-0.1	-0.4	-0.3	0.7	1.1	0.5	1.4	0.2	-0.2	0.3	-0.0	-0.7	1.1	-0.3
Leg fat percentage (left)	0.3	1.1	5.4	-1.3	-1.9	-1.0	0.8	-0.8	0.1	-1.2	-0.5	-0.5	-0.8	-0.6	-0.9	-1.1	1.1	1.7	0.4	2.3	-0.0	-1.2	0.2	-0.5	-1.1	1.7	-0.8
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	2.4	0.5	0.7	0.2	0.3	0.6	0.1	0.5	0.7	0.6	0.4	0.3	0.4	1.6	0.6	-0.8	-0.4	-1.3	0.1	0.6	0.1	0.3	0.7	-0.7	0.5
Schizophrenia vs Biploar Disorder	0.2	0.3	0.8	0.6	0.5	0.6	-0.8	0.6	0.9	0.7	0.5	0.2	0.7	0.5	0.5	0.6	0.5	0.6	0.5	0.4	0.6	0.3	0.7	0.5	0.6	0.5	0.5
Ovarian Cancer	0.2	0.2	2.4	-0.2	0.3	-0.8	0.2	0.3	-0.3	0.6	0.1	0.4	-0.2	0.3	0.3	1.0	1.6	-0.3	0.3	-0.4	0.0	0.6	-0.1	0.2	0.0	-0.3	0.3
Crohns Disease (2012)	0.2	0.3	2.1	-0.0	1.5	-0.9	-0.4	0.2	-0.2	0.5	0.5	0.8	0.3	0.5	0.3	0.4	0.8	0.4	0.8	0.3	0.3	1.0	0.3	0.5	-0.5	0.4	0.3
Lupus	0.2	0.4	3.3	0.2	-0.4	-0.3	0.3	0.1	-0.5	-0.2	0.1	0.3	-0.4	0.2	0.4	-0.8	-1.8	-0.9	-0.1	-1.2	-0.1	0.1	-0.5	0.2	0.6	-1.1	0.4
Neuroticism (2016)	0.2	0.3	1.0	0.3	0.6	0.2	1.0	0.4	0.6	0.8	0.6	0.6	0.1	0.5	0.5	0.3	1.0	0.5	0.8	0.3	0.6	0.2	0.6	0.5	0.7	0.4	0.5
Primary Biliary Cirrhosis	0.2	0.3	1.5	0.8	-0.4	-0.5	1.2	0.5	-0.2	0.1	0.2	0.8	-0.1	0.5	0.7	0.4	1.0	-0.4	0.3	-0.5	0.2	0.3	-0.1	0.4	0.5	-0.5	0.6
Schizophrenia (2014)	0.2	0.4	1.9	-0.6	-1.4	-1.1	0.4	-0.5	-0.7	-0.6	-0.8	-0.3	-0.9	-0.7	-0.6	0.3	0.7	-0.6	-0.6	-0.4	-0.5	-0.8	-0.7	-0.7	-0.0	-0.7	-0.6
Lung FEV1/FVC ratio	0.2	1.0	5.8	0.3	-2.4	1.6	2.1	0.5	0.8	-0.7	0.1	-0.4	-0.2	-0.3	0.3	1.2	0.8	-0.3	-0.3	-0.3	0.2	-1.6	-0.2	-0.3	2.1	-0.7	0.1
Hand grip strength (left)	0.2	0.5	2.2	-0.5	-0.9	-0.3	-0.1	-0.3	-0.2	-0.5	-0.1	-0.6	-0.3	-0.7	-0.5	0.1	-0.4	-1.3	-1.3	-1.5	-0.9	-0.8	-0.7	-0.8	0.5	-1.4	-0.5
Diabetes (mother)	0.2	0.3	1.4	-0.2	-1.2	0.4	0.1	-0.0	0.9	-0.2	0.0	-0.1	-0.3	-0.3	-0.2	-0.6	0.6	0.9	0.1	1.1	0.3	-0.8	0.3	-0.1	0.4	0.7	-0.1
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	0.8	0.3	0.7	-0.5	0.2	0.1	0.4	0.2	0.2	0.3	-0.0	0.3	0.3	-0.3	0.8	0.9	0.7	0.9	0.5	0.2	0.5	0.5	-0.1	0.9	0.3
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	1.0	-0.1	0.2	0.3	0.2	0.1	0.6	-0.4	0.2	-0.1	0.3	0.2	0.0	0.1	0.8	1.0	0.4	1.0	0.5	-0.2	0.5	0.2	0.1	0.9	0.1
Qualifications: CSEs or equivalent	0.2	0.3	1.2	0.2	-0.0	-1.0	0.8	-0.1	-0.9	-0.1	-0.1	-0.3	-0.2	-0.0	0.1	-0.2	-0.1	-1.1	-0.4	-1.1	-0.5	-0.0	-0.7	-0.2	0.0	-1.1	0.0
Medication: Levothyroxine sodium	0.2	0.4	1.7	0.2	-0.9	0.0	0.8	-0.2	-0.3	-0.0	0.0	-0.1	-0.1	-0.5	-0.3	-0.1	-0.8	-1.1	-0.8	-1.3	-0.7	-0.4	-0.6	-0.5	0.5	-1.2	-0.3
Waist circumference	0.2	0.9	2.6	-1.5	-1.6	-0.6	1.4	-1.0	0.2	-1.1	-0.2	-0.7	-0.3	-1.2	-1.2	-1.6	0.4	0.4	-1.0	0.6	-0.7	-1.5	-0.2	-1.0	-0.6	0.4	-1.2
Alcohol usually taken with meals	0.2	0.4	1.5	-0.4	0.2	1.0	0.5	-0.2	1.0	0.1	0.1	-0.6	0.6	0.0	-0.2	-1.0	-0.3	1.1	0.4	1.2	0.3	-0.3	0.6	-0.1	0.0	1.1	-0.3
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	1.5	0.2	1.1	-0.0	0.2	0.3	0.2	0.4	0.6	0.4	0.4	0.2	0.2	0.7	1.2	-0.3	-0.4	-0.6	0.0	0.5	0.3	0.2	0.2	-0.1	0.2
Qualifications: None of the above	0.2	0.5	1.7	1.3	-0.1	0.8	-0.4	0.8	0.9	0.4	0.9	1.3	0.9	0.4	0.7	0.3	0.0	0.1	-0.0	-0.4	0.6	0.2	0.6	0.7	1.1	-0.0	0.8
Impedance of arm (right)	0.2	0.8	4.5	0.1	0.2	0.8	0.2	0.4	0.7	0.1	-0.2	0.3	-0.3	0.6	0.5	0.6	1.7	1.7	1.4	2.1	1.0	-0.1	0.7	0.6	0.0	1.6	0.5
Happiness	0.2	0.2	1.3	0.3	1.1	0.3	0.5	0.4	0.6	0.6	0.9	0.3	0.5	0.2	0.1	0.2	0.7	0.4	0.3	0.0	0.3	0.5	0.7	0.4	0.2	0.4	0.2
Qualifications: A levels/AS levels or equivalent	0.2	0.3	1.4	-0.4	1.0	0.7	0.6	0.2	0.8	0.5	-0.0	-0.2	0.6	0.5	0.2	0.0	1.2	0.7	0.3	0.8	0.5	0.6	0.6	0.2	-0.3	1.0	0.2
Impedance of arm (left)	0.2	0.9	2.6	0.6	0.7	0.8	0.4	0.8	0.6	0.6	0.2	0.8	0.0	1.0	1.0	0.8	1.4	1.4	1.6	1.5	1.2	0.6	0.8	1.0	0.3	1.4	1.0
Trunk predicted mass	0.2	1.4	5.2	0.8	0.1	1.6	2.1	1.0	2.3	1.4	1.8	1.0	2.2	0.8	0.8	-0.2	0.1	0.8	-0.1	-0.1	1.0	0.4	1.6	0.8	1.6	0.8	0.8
Hair/balding pattern: Pattern 4	0.2	0.5	1.6	-0.8	-0.2	-1.1	-1.3	-0.7	-0.2	-0.5	-0.7	-0.4	-0.6	-0.4	-0.7	-0.5	1.0	0.8	0.3	1.3	-0.3	-0.3	-0.1	-0.4	-1.1	0.8	-0.7
Peak expiratory flow (PEF)	0.2	0.5	4.1	-0.6	-2.0	0.2	0.1	-0.7	-0.2	-0.8	-1.0	-0.8	-0.6	-0.7	-0.7	-0.5	-0.4	-0.1	-0.8	0.4	-0.5	-1.1	-0.6	-0.8	-0.5	0.0	-0.7
High blood pressure (siblings)	0.2	0.3	3.2	0.2	-1.8	-0.0	0.4	0.1	0.5	-0.2	-0.0	0.4	-0.2	-0.3	-0.0	-0.3	0.5	-0.0	-0.2	0.0	0.1	-1.1	-0.1	-0.2	1.0	-0.2	0.0
Body fat percentage	0.2	1.0	4.6	-1.1	-1.7	-0.3	1.6	-0.5	0.6	-0.9	-0.0	-0.2	-0.3	-0.5	-0.7	-1.2	1.0	1.7	0.4	2.1	0.2	-1.1	0.5	-0.3	-0.6	1.7	-0.6
Leg fat percentage (right)	0.2	0.7	3.5	-0.9	-1.9	-0.4	1.2	-0.4	0.5	-0.9	0.0	-0.1	-0.3	-0.4	-0.5	-0.9	1.0	1.4	0.3	1.7	0.2	-0.9	0.4	-0.2	-0.5	1.4	-0.5
Arm fat-free mass (right)	0.2	1.0	4.5	0.5	-0.2	1.0	2.1	0.8	1.9	1.1	1.7	1.0	1.9	0.6	0.6	-0.4	-0.1	0.6	-0.3	-0.2	0.8	0.4	1.4	0.6	1.3	0.6	0.6
Qualifications: College or University degree	0.2	0.6	1.7	-1.3	1.3	-0.7	-0.7	-0.6	-1.0	0.1	-0.8	-0.7	-0.8	-0.5	-0.7	0.1	0.1	-0.9	-0.8	-0.6	-0.9	0.2	-0.8	-0.7	-1.2	-0.6	-0.7
Heart disease (mother)	0.2	0.2	1.1	0.4	0.1	0.0	-0.4	0.3	0.4	0.3	0.5	0.6	0.4	0.4	0.4	-0.2	-0.0	0.9	1.1	0.8	0.6	0.2	0.5	0.5	0.4	0.6	0.4
Whole body fat mass	0.2	0.8	3.3	-0.9	-1.5	0.0	1.8	-0.3	1.1	-0.4	0.4	0.1	0.4	-0.3	-0.4	-1.2	0.9	1.7	0.2	1.8	0.4	-0.8	0.8	-0.1	-0.2	1.7	-0.4
Leg fat mass (right)	0.2	0.6	2.8	-0.7	-1.5	0.0	1.7	-0.2	1.0	-0.4	0.5	0.1	0.3	-0.3	-0.4	-0.9	0.9	1.4	0.1	1.4	0.3	-0.7	0.7	-0.1	-0.1	1.4	-0.3
Had major operations	0.2	0.2	1.3	0.6	-0.0	0.1	0.1	0.6	0.1	0.0	0.4	1.1	0.1	0.5	0.7	0.7	0.3	0.1	0.7	-0.1	0.6	0.2	0.2	0.6	0.9	-0.1	0.7
Whole body fat-free mass	0.2	1.0	5.0	0.3	-0.2	1.2	2.2	0.7	2.0	1.0	1.6	0.7	1.8	0.5	0.4	-0.5	0.1	0.9	-0.2	0.2	0.8	0.2	1.4	0.5	1.2	0.9	0.4
Qualifications: nursing, teaching	0.2	0.3	1.4	-1.0	0.3	-0.4	-0.3	-0.5	0.1	-0.3	-0.5	-0.2	-0.5	-0.3	-0.6	-0.2	1.2	0.7	-0.0	1.1	-0.0	-0.3	0.1	-0.4	-0.9	0.9	-0.5
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	1.0	-0.4	0.8	-0.6	0.4	0.1	-0.2	0.9	0.1	0.8	-0.0	0.4	0.2	0.6	1.0	0.6	0.9	0.6	0.3	0.8	0.3	0.4	-0.6	0.6	0.2
Osteoarthritis (self-reported)	0.2	0.3	1.4	-0.4	0.5	-0.9	-0.6	-0.6	-0.7	-0.1	-0.4	-0.3	-0.4	-0.5	-0.6	-0.9	-0.6	-0.2	-0.5	0.1	-0.6	-0.1	-0.4	-0.4	-1.2	0.0	-0.6
Average weekly champagne plus white wine intake	0.2	0.3	1.5	-0.4	0.0	0.6	0.6	-0.0	0.8	0.2	-0.0	-0.3	0.0	0.0	-0.1	-0.0	1.2	1.0	0.2	1.2	0.3	-0.3	0.5	-0.0	-0.2	1.1	-0.2
Basal metabolic rate	0.2	0.9	5.4	0.1	-0.4	1.0	2.3	0.5	1.9	0.8	1.4	0.6	1.7	0.4	0.3	-0.7	0.1	0.9	-0.2	0.3	0.7	0.0	1.3	0.4	1.0	0.9	0.3
Arm fat-free mass (left)	0.2	0.9	4.1	0.2	-0.5	1.0	2.0	0.6	1.9	0.8	1.4	0.7	1.8	0.4	0.4	-0.6	0.0	0.7	-0.4	0.1	0.7	0.0	1.3	0.4	1.2	0.8	0.4
Average weekly beer plus cider intake	0.2	0.3	2.1	0.8	0.3	0.3	-0.5	0.2	-0.3	-0.0	0.2	0.1	0.4	0.1	0.3	-0.3	-0.5	-1.1	-0.6	-1.4	-0.1	0.2	-0.3	0.1	0.6	-1.1	0.3
Ever had prostate specific antigen (PSA) test	0.2	0.2	1.1	-0.4	1.0	0.4	-0.2	-0.4	0.1	0.3	0.1	-0.3	0.4	-0.2	-0.5	-0.9	-1.0	0.2	-0.1	0.2	-0.3	0.6	0.2	-0.2	-0.7	0.4	-0.5
Alcohol drinker status: Previous	0.2	0.3	3.1	-0.2	-0.5	-0.4	0.2	0.2	0.2	-0.6	0.2	0.1	-0.7	-0.0	0.1	0.9	1.8	0.6	0.5	0.6	0.3	-0.4	0.2	0.2	0.3	0.3	0.1
Leg fat mass (left)	0.2	0.8	3.5	-1.0	-1.5	-0.4	1.3	-0.4	0.8	-0.7	0.1	-0.2	-0.0	-0.4	-0.6	-1.0	1.0	1.6	0.2	1.9	0.2	-0.9	0.6	-0.3	-0.5	1.6	-0.6
Arm predicted mass (left)	0.2	0.8	3.7	0.2	-0.6	1.0	1.9	0.5	1.8	0.7	1.4	0.6	1.7	0.3	0.3	-0.7	-0.1	0.6	-0.4	-0.0	0.6	-0.1	1.2	0.3	1.2	0.6	0.3
Reaction Time	0.1	0.3	2.0	0.0	0.1	0.3	0.5	-0.0	-0.2	0.1	0.2	-0.3	0.0	-0.4	-0.2	0.3	0.3	-1.1	-0.8	-1.4	-0.6	-0.1	-0.4	-0.3	0.5	-1.2	-0.2
Verbal and Numeric Reasoning (VNR)	0.1	0.3	1.2	-0.3	0.8	1.0	1.1	0.0	0.1	0.5	0.4	-0.4	0.4	0.2	0.2	-0.5	-1.0	-0.5	-0.7	-0.9	-0.1	0.5	0.1	0.1	-0.0	-0.3	0.0
Blood White Count	0.1	0.9	6.9	0.0	2.6	-1.4	-0.1	0.2	-0.4	1.2	0.9	1.5	1.4	0.6	0.3	-0.5	0.9	0.0	0.5	-0.5	0.1	2.0	0.5	0.7	-0.8	0.2	0.5
Allergy or Eczema	0.1	0.2	0.8	-0.5	0.9	-0.8	0.4	-0.4	-0.1	-0.2	-0.1	-0.4	0.0	-0.3	-0.4	-0.4	0.6	0.0	-0.4	0.1	-0.3	-0.2	-0.1	-0.3	-0.6	0.2	-0.4
Hypothyroidism (self reported)	0.1	0.2	1.5	-0.1	-1.0	0.2	0.6	-0.2	0.4	0.0	-0.3	-0.1	0.0	-0.1	-0.2	-0.1	-0.1	0.9	0.3	1.2	0.1	-0.3	0.3	-0.1	-0.5	1.0	-0.3
Leg fat-free mass (left)	0.1	0.7	5.5	-0.2	-0.4	0.8	2.3	0.3	1.6	0.6	1.2	0.3	1.3	0.1	0.0	-0.7	0.1	0.9	-0.3	0.5	0.5	-0.1	1.1	0.2	0.7	1.0	0.0
Hand grip strength (right)	0.1	0.2	0.8	-0.3	0.1	0.3	0.0	0.1	0.6	0.0	0.5	-0.1	0.6	-0.2	-0.2	0.3	0.4	-0.5	-0.8	-0.9	-0.2	-0.0	0.2	-0.3	0.6	-0.4	-0.2
Taking other prescription medications	0.1	0.2	1.7	0.4	-0.6	-0.7	-0.6	0.1	0.2	-0.1	-0.2	0.3	-0.3	-0.0	-0.1	0.4	1.3	0.5	0.2	0.6	0.2	-0.0	0.2	0.1	-0.2	0.6	0.0
Hayfever, allergic rhinitis or eczema	0.1	0.1	0.6	-0.4	0.4	-0.1	0.8	-0.2	0.5	0.0	0.2	-0.4	0.5	-0.3	-0.3	-0.6	0.3	-0.1	-0.7	-0.3	-0.2	-0.3	0.1	-0.3	0.1	-0.0	-0.3
Supplements: Glucosamine	0.1	0.1	0.4	-0.2	-0.6	0.3	0.4	0.0	-0.1	0.0	0.1	0.0	-0.4	-0.2	-0.1	0.2	0.1	-0.3	-0.1	-0.3	-0.2	-0.6	-0.2	-0.2	0.6	-0.5	-0.1
Diverticular disease/diverticulitis (self-reported)	0.1	0.2	1.1	-0.2	-0.2	-0.2	-0.1	-0.4	0.2	-0.2	-0.1	0.0	0.1	-0.0	-0.2	-0.8	-0.0	0.9	0.4	1.1	0.1	-0.3	0.2	-0.0	-0.5	0.8	-0.3
Leg predicted mass (left)	0.1	0.6	5.2	-0.3	-0.4	0.7	2.3	0.2	1.5	0.5	1.1	0.3	1.2	0.0	-0.1	-0.7	0.1	0.9	-0.4	0.4	0.4	-0.2	1.0	0.1	0.6	0.9	-0.1
Nervous feelings	0.1	0.2	2.4	-0.0	0.5	0.5	-0.3	-0.2	-0.3	-0.2	0.0	-0.2	0.1	-0.2	-0.0	-0.7	-1.5	-0.7	-0.2	-0.8	-0.3	-0.3	-0.4	-0.3	0.4	-0.8	-0.1
Hayfever/allergic rhinitis (self-reported)	0.1	0.2	0.5	-0.2	-0.7	-0.0	0.5	-0.2	-0.1	-0.4	-0.4	-0.5	-0.5	-0.5	-0.4	0.4	0.1	-0.4	-0.7	-0.3	-0.4	-0.4	-0.3	-0.5	-0.2	-0.3	-0.4
Weight	0.1	0.6	4.2	-0.5	-1.0	0.4	2.0	-0.0	1.4	0.0	0.8	0.1	1.0	-0.1	-0.2	-1.2	0.2	1.0	-0.3	0.8	0.3	-0.6	0.9	-0.0	0.4	1.1	-0.2
Hip circumference	0.1	0.5	2.1	-1.0	-0.9	0.0	1.1	-0.6	0.7	-0.5	0.2	-0.7	0.2	-0.8	-0.8	-1.4	-0.0	0.7	-0.7	0.7	-0.3	-0.9	0.3	-0.6	-0.3	0.7	-0.8
Depression (self-reported)	0.1	0.1	0.4	0.3	-0.0	-0.3	-0.6	0.2	0.0	0.1	0.1	0.5	-0.3	0.2	0.3	0.1	0.7	0.3	0.5	0.3	0.4	0.1	0.1	0.4	0.1	0.2	0.3
Lung cancer (father)	0.1	0.1	1.1	-0.1	-0.1	0.2	-1.0	0.0	0.4	0.0	0.0	0.1	0.0	-0.2	-0.1	-0.1	0.0	0.4	0.1	0.4	0.2	-0.2	0.2	-0.0	0.2	0.4	-0.1
Tense / ‘highly strung’	0.1	0.2	1.6	0.2	1.3	-0.7	-0.9	-0.2	-0.4	-0.1	0.1	0.2	0.2	0.2	0.0	-0.7	-0.8	0.0	0.4	-0.0	0.0	0.6	-0.0	0.2	-0.5	0.0	0.1
Hypothyroidism/myxoedema (self-reported)	0.1	0.3	0.8	0.5	0.2	0.7	0.9	0.4	0.7	0.8	0.6	0.5	0.8	0.4	0.3	0.6	0.2	0.6	0.5	0.3	0.4	0.5	0.7	0.4	0.2	0.6	0.3
Mean time to correctly identify matches	0.1	0.2	1.0	0.2	0.6	0.7	1.0	0.2	0.2	0.5	0.5	-0.3	0.2	-0.0	0.1	0.4	0.6	-0.6	-0.5	-0.9	-0.2	0.3	0.1	0.0	0.3	-0.5	0.1
Suffer from ‘nerves’	0.1	0.1	1.1	0.2	0.2	0.8	-0.7	0.0	0.4	-0.1	0.2	-0.1	0.1	0.1	0.0	-0.2	-1.0	0.4	0.2	0.4	0.2	-0.1	0.3	0.0	0.1	0.4	-0.0
Knee pain experienced in last month	0.1	0.2	1.2	0.9	-0.2	0.1	0.3	0.5	0.4	0.4	0.8	0.5	0.5	0.0	0.2	0.5	0.3	-0.4	-0.2	-0.9	0.1	-0.1	0.2	0.2	1.1	-0.6	0.3
Leg fat-free mass (right)	0.1	0.4	3.3	-0.6	-0.4	0.1	1.8	-0.2	1.1	0.2	0.7	-0.0	0.9	-0.2	-0.4	-1.1	-0.2	0.8	-0.4	0.7	0.1	-0.4	0.7	-0.2	0.1	0.9	-0.4
Osteoporosis (self-reported)	0.1	0.1	0.6	-0.1	-0.6	-0.0	0.0	-0.1	0.1	-0.3	-0.1	-0.4	0.2	-0.3	-0.2	-0.6	-0.2	-0.6	-0.8	-0.7	-0.3	-0.3	-0.2	-0.3	0.2	-0.5	-0.2
Whole body water mass	0.1	0.8	4.5	0.2	-0.3	1.0	2.1	0.5	1.8	0.9	1.4	0.6	1.7	0.3	0.3	-0.6	-0.0	0.7	-0.4	0.0	0.6	0.0	1.2	0.3	1.1	0.7	0.3
Leg predicted mass (right)	0.1	0.5	3.3	-0.6	-0.4	0.2	1.8	-0.2	1.1	0.2	0.7	-0.0	0.9	-0.2	-0.4	-1.1	-0.1	0.9	-0.4	0.7	0.2	-0.4	0.7	-0.2	0.1	1.0	-0.4
Ever depressed for a whole week	0.1	0.1	1.3	-0.5	0.6	-0.4	-0.2	-0.2	0.1	-0.2	0.1	-0.5	-0.2	-0.2	-0.4	0.1	1.1	0.2	-0.2	0.3	-0.2	-0.3	0.0	-0.3	-0.2	0.2	-0.4
Pain experienced in last month	0.1	0.1	0.8	-0.3	0.7	0.5	0.0	-0.1	-0.1	-0.0	-0.3	-0.8	-0.1	0.1	0.1	-0.6	-0.9	0.1	-0.0	0.2	0.1	0.2	0.0	0.1	-0.5	0.3	0.1
Age at first live birth	0.0	0.1	0.3	-0.2	0.4	-0.1	0.2	0.1	-0.2	0.4	-0.5	-0.1	-0.0	0.4	0.3	0.4	-0.2	-0.1	-0.3	0.1	0.2	0.4	-0.1	0.2	-0.6	0.2	0.2
Age at last live birth	0.0	0.1	0.3	-0.1	-0.1	0.1	0.4	0.1	-0.2	0.3	-0.5	0.0	0.1	0.3	0.3	0.2	-0.4	-0.4	-0.4	-0.3	0.0	0.3	-0.2	0.0	-0.2	-0.1	0.2